SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3n1q'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1E7B_A_HLTA4001_1
(SERUM ALBUMIN)		 3n1q DESERT HEDGEHOG
PROTEIN
(Homo
sapiens) 		4 / 5 ARG B 102
ALA B 188
ASP B 172
GLY B  61
 None
 1.12A 1e7bA-3n1qB:
undetectable		 1e7bA-3n1qB:
14.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NT2_A_SAMA301_0
(FIBRILLARIN-LIKE
PRE-RRNA PROCESSING
PROTEIN)		 3n1q DESERT HEDGEHOG
PROTEIN
(Homo
sapiens) 		5 / 12 GLY B 128
ALA B 146
SER B 185
ALA B  95
ASP B 148
 None
None
None
CA  B 191 ( 4.4A)
ZN  B 190 (-2.5A)
 1.20A 1nt2A-3n1qB:
undetectable		 1nt2A-3n1qB:
23.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3S8P_A_SAMA500_1
(HISTONE-LYSINE
N-METHYLTRANSFERASE
SUV420H1)		 3n1q DESERT HEDGEHOG
PROTEIN
(Homo
sapiens) 		3 / 3 HIS B 141
SER B  60
GLU B  54
 ZN  B 190 (-3.5A)
None
None
 0.73A 3s8pA-3n1qB:
undetectable		 3s8pA-3n1qB:
22.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HVR_A_SALA203_1
(3-HYDROXYANTHRANILAT
E 3,4-DIOXYGENASE)		 3n1q DESERT HEDGEHOG
PROTEIN
(Homo
sapiens) 		4 / 7 HIS B 141
ASP B 148
HIS B 135
GLU B 177
 ZN  B 190 (-3.5A)
ZN  B 190 (-2.5A)
None
ZN  B 190 (-3.6A)
 1.12A 4hvrA-3n1qB:
undetectable		 4hvrA-3n1qB:
21.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O4D_A_ACTA406_0
(INOSITOL
HEXAKISPHOSPHATE
KINASE)		 3n1q DESERT HEDGEHOG
PROTEIN
(Homo
sapiens) 		4 / 7 ASP B  96
THR B 126
ARG B 124
PHE B  87
 CA  B 192 (-2.6A)
None
None
None
 1.44A 4o4dA-3n1qB:
undetectable		 4o4dA-3n1qB:
17.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KGP_A_GCSA407_1
(PREDICTED
ACETYLTRANSFERASE)		 3n1q DESERT HEDGEHOG
PROTEIN
(Homo
sapiens) 		4 / 8 ARG B  69
GLY B 133
ASP B 130
TRP B 129
 None
None
CA  B 191 (-3.8A)
None
 1.11A 5kgpA-3n1qB:
undetectable		 5kgpA-3n1qB:
16.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XXI_A_LSNA501_1
(CYTOCHROME P450 2C9)		 3n1q DESERT HEDGEHOG
PROTEIN
(Homo
sapiens) 		5 / 12 VAL B 182
ASN B 157
GLY B 160
ALA B 163
LEU B 110
 None
 1.09A 5xxiA-3n1qB:
undetectable		 5xxiA-3n1qB:
20.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AK3_A_P2EA1201_1
(PROSTAGLANDIN E2
RECEPTOR EP3
SUBTYPE,SOLUBLE
CYTOCHROME B562)		 3n1q DESERT HEDGEHOG
PROTEIN
(Homo
sapiens) 		4 / 4 PRO B  83
MET B  99
GLY B 128
VAL B 107
 None
 1.37A 6ak3A-3n1qB:
undetectable		 6ak3A-3n1qB:
19.41