SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3n1t'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_T_TRPT81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 3n1t HIT-LIKE PROTEIN
HINT
(Escherichia
coli) 		4 / 7 GLY A 107
ALA A  73
HIS A  39
THR A  38
 None
 0.91A 1c9sT-3n1tA:
undetectable
1c9sU-3n1tA:
undetectable		 1c9sT-3n1tA:
22.22
1c9sU-3n1tA:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AZX_A_TRPA602_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 3n1t HIT-LIKE PROTEIN
HINT
(Escherichia
coli) 		4 / 8 LEU A  41
GLU A  76
LEU A 104
HIS A 103
 5GP  A 200 (-4.2A)
None
None
5GP  A 200 (-4.1A)
 0.89A 2azxA-3n1tA:
undetectable		 2azxA-3n1tA:
12.86
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3O1C_A_ADNA127_1
(HISTIDINE TRIAD
NUCLEOTIDE-BINDING
PROTEIN 1)		 3n1t HIT-LIKE PROTEIN
HINT
(Escherichia
coli) 		8 / 10 ILE A   6
PHE A   7
ILE A  10
ASP A  31
ILE A  32
SER A  33
LEU A  41
HIS A 103
 5GP  A 200 (-3.6A)
None
None
5GP  A 200 (-2.3A)
5GP  A 200 (-3.6A)
5GP  A 200 (-4.7A)
5GP  A 200 (-4.2A)
5GP  A 200 (-4.1A)
 0.61A 3o1cA-3n1tA:
20.4		 3o1cA-3n1tA:
42.31
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3O1X_A_ADNA1450_1
(HISTIDINE TRIAD
NUCLEOTIDE-BINDING
PROTEIN 1)		 3n1t HIT-LIKE PROTEIN
HINT
(Escherichia
coli) 		7 / 10 ILE A   6
PHE A   7
ILE A  10
ASP A  31
ILE A  32
LEU A  41
HIS A 103
 5GP  A 200 (-3.6A)
None
None
5GP  A 200 (-2.3A)
5GP  A 200 (-3.6A)
5GP  A 200 (-4.2A)
5GP  A 200 (-4.1A)
 0.62A 3o1xA-3n1tA:
20.2		 3o1xA-3n1tA:
42.31
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3O1X_A_ADNA1450_1
(HISTIDINE TRIAD
NUCLEOTIDE-BINDING
PROTEIN 1)		 3n1t HIT-LIKE PROTEIN
HINT
(Escherichia
coli) 		6 / 10 PHE A   7
ILE A  10
ASP A  31
SER A  33
LEU A  41
HIS A 103
 None
None
5GP  A 200 (-2.3A)
5GP  A 200 (-4.7A)
5GP  A 200 (-4.2A)
5GP  A 200 (-4.1A)
 0.63A 3o1xA-3n1tA:
20.2		 3o1xA-3n1tA:
42.31
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3QGZ_A_ADNA127_1
(HISTIDINE TRIAD
NUCLEOTIDE-BINDING
PROTEIN 1)		 3n1t HIT-LIKE PROTEIN
HINT
(Escherichia
coli) 		7 / 10 ILE A   6
PHE A   7
ILE A  10
ASP A  31
ILE A  32
LEU A  41
HIS A 103
 5GP  A 200 (-3.6A)
None
None
5GP  A 200 (-2.3A)
5GP  A 200 (-3.6A)
5GP  A 200 (-4.2A)
5GP  A 200 (-4.1A)
 0.67A 3qgzA-3n1tA:
20.4		 3qgzA-3n1tA:
42.31
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3QGZ_A_ADNA127_1
(HISTIDINE TRIAD
NUCLEOTIDE-BINDING
PROTEIN 1)		 3n1t HIT-LIKE PROTEIN
HINT
(Escherichia
coli) 		7 / 10 PHE A   7
ILE A  10
ASP A  31
ILE A  32
SER A  33
LEU A  41
HIS A 103
 None
None
5GP  A 200 (-2.3A)
5GP  A 200 (-3.6A)
5GP  A 200 (-4.7A)
5GP  A 200 (-4.2A)
5GP  A 200 (-4.1A)
 0.70A 3qgzA-3n1tA:
20.4		 3qgzA-3n1tA:
42.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_L_TRPL101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3n1t HIT-LIKE PROTEIN
HINT
(Escherichia
coli) 		4 / 8 GLY A 107
ALA A  73
HIS A  39
THR A  38
 None
 0.96A 5eevL-3n1tA:
undetectable
5eevV-3n1tA:
undetectable		 5eevL-3n1tA:
22.22
5eevV-3n1tA:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_L_TRPL101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3n1t HIT-LIKE PROTEIN
HINT
(Escherichia
coli) 		4 / 8 GLY A 107
ALA A  73
HIS A  39
THR A  38
 None
 0.96A 5eewL-3n1tA:
undetectable
5eewV-3n1tA:
undetectable		 5eewL-3n1tA:
22.22
5eewV-3n1tA:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_L_TRPL101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3n1t HIT-LIKE PROTEIN
HINT
(Escherichia
coli) 		4 / 8 GLY A 107
ALA A  73
HIS A  39
THR A  38
 None
 0.96A 5ef3L-3n1tA:
undetectable
5ef3V-3n1tA:
undetectable		 5ef3L-3n1tA:
22.22
5ef3V-3n1tA:
22.22
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5KM9_B_ADNB201_1
(HISTIDINE TRIAD
NUCLEOTIDE-BINDING
PROTEIN 2,
MITOCHONDRIAL)		 3n1t HIT-LIKE PROTEIN
HINT
(Escherichia
coli) 		7 / 12 ILE A   6
PHE A   7
ILE A  10
ASP A  31
LEU A  41
VAL A  97
HIS A 103
 5GP  A 200 (-3.6A)
None
None
5GP  A 200 (-2.3A)
5GP  A 200 (-4.2A)
5GP  A 200 (-3.6A)
5GP  A 200 (-4.1A)
 0.34A 5km9B-3n1tA:
20.2		 5km9B-3n1tA:
36.36
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5UVM_B_ADNB207_1
(HISTIDINE TRIAD
(HIT) PROTEIN)		 3n1t HIT-LIKE PROTEIN
HINT
(Escherichia
coli) 		7 / 12 PHE A   7
ILE A  10
ASP A  31
ILE A  32
LEU A  41
VAL A  97
HIS A 103
 None
None
5GP  A 200 (-2.3A)
5GP  A 200 (-3.6A)
5GP  A 200 (-4.2A)
5GP  A 200 (-3.6A)
5GP  A 200 (-4.1A)
 0.37A 5uvmB-3n1tA:
20.1		 5uvmB-3n1tA:
37.75