SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3n26'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Q13_A_TESA501_1
(PROSTAGLANDIN-E2
9-REDUCTASE)		 3n26 AMINO ACID ABC
TRANSPORTER,
PERIPLASMIC AMINO
ACID-BINDING PROTEIN
(Chlamydia
pneumoniae) 		4 / 6 TYR A  41
GLU A 186
PRO A 187
VAL A 192
 ARG  A 500 (-3.5A)
ARG  A 500 (-2.9A)
None
None
 1.14A 1q13A-3n26A:
undetectable		 1q13A-3n26A:
23.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SN5_D_T3D602_1
(TRANSTHYRETIN)		 3n26 AMINO ACID ABC
TRANSPORTER,
PERIPLASMIC AMINO
ACID-BINDING PROTEIN
(Chlamydia
pneumoniae) 		5 / 12 LEU A  95
VAL A 243
LEU A 238
GLU A  66
VAL A  35
 None
 1.07A 1sn5B-3n26A:
undetectable
1sn5D-3n26A:
undetectable		 1sn5B-3n26A:
19.51
1sn5D-3n26A:
19.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F8D_B_BEZB1003_0
(HTH-TYPE
TRANSCRIPTIONAL
REGULATOR BENM)		 3n26 AMINO ACID ABC
TRANSPORTER,
PERIPLASMIC AMINO
ACID-BINDING PROTEIN
(Chlamydia
pneumoniae) 		5 / 10 LEU A 218
GLY A 217
LEU A 110
LEU A 111
LEU A  86
 None
 1.07A 2f8dB-3n26A:
9.1		 2f8dB-3n26A:
26.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3R9S_A_BEZA264_0
(CARNITINYL-COA
DEHYDRATASE)		 3n26 AMINO ACID ABC
TRANSPORTER,
PERIPLASMIC AMINO
ACID-BINDING PROTEIN
(Chlamydia
pneumoniae) 		4 / 6 ALA A  61
ILE A  58
LEU A  72
ALA A  93
 None
 0.87A 3r9sA-3n26A:
undetectable		 3r9sA-3n26A:
22.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3R9S_C_BEZC264_0
(CARNITINYL-COA
DEHYDRATASE)		 3n26 AMINO ACID ABC
TRANSPORTER,
PERIPLASMIC AMINO
ACID-BINDING PROTEIN
(Chlamydia
pneumoniae) 		4 / 6 ALA A  61
ILE A  58
LEU A  72
ALA A  93
 None
 0.86A 3r9sC-3n26A:
undetectable		 3r9sC-3n26A:
22.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A99_A_MIYA392_1
(TETX2 PROTEIN)		 3n26 AMINO ACID ABC
TRANSPORTER,
PERIPLASMIC AMINO
ACID-BINDING PROTEIN
(Chlamydia
pneumoniae) 		5 / 9 LEU A 253
TYR A 114
SER A  99
GLN A 150
VAL A 213
 None
None
ARG  A 500 (-2.9A)
ARG  A 500 ( 4.0A)
None
 1.36A 4a99A-3n26A:
0.6
4a99C-3n26A:
0.6		 4a99A-3n26A:
20.70
4a99C-3n26A:
20.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Y1Y_A_HNQA201_1
(BROMODOMAIN-CONTAINI
NG PROTEIN 4)		 3n26 AMINO ACID ABC
TRANSPORTER,
PERIPLASMIC AMINO
ACID-BINDING PROTEIN
(Chlamydia
pneumoniae) 		4 / 8 VAL A 184
LEU A 205
TYR A 153
ILE A 160
 None
 0.83A 5y1yA-3n26A:
undetectable		 5y1yA-3n26A:
19.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BRD_B_RFPB502_2
(RIFAMPIN
MONOOXYGENASE)		 3n26 AMINO ACID ABC
TRANSPORTER,
PERIPLASMIC AMINO
ACID-BINDING PROTEIN
(Chlamydia
pneumoniae) 		4 / 6 VAL A 171
LEU A 207
ARG A 204
PRO A 187
 None
 1.15A 6brdB-3n26A:
undetectable		 6brdB-3n26A:
21.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FDY_U_DB8U302_1
(-)		 3n26 AMINO ACID ABC
TRANSPORTER,
PERIPLASMIC AMINO
ACID-BINDING PROTEIN
(Chlamydia
pneumoniae) 		5 / 9 LEU A  86
VAL A 220
LEU A  68
GLU A 227
ILE A 231
 None
 1.34A 6fdyU-3n26A:
undetectable		 6fdyU-3n26A:
23.15