SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3n28'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1IE4_B_T44B328_1
(TRANSTHYRETIN)		 3n28 PHOSPHOSERINE
PHOSPHATASE
(Vibrio
cholerae) 		4 / 8 ALA A 280
LEU A 282
ALA A 296
THR A 298
 None
 0.92A 1ie4B-3n28A:
undetectable
1ie4D-3n28A:
undetectable		 1ie4B-3n28A:
18.03
1ie4D-3n28A:
18.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PO5_A_CHDA501_0
(FERROCHELATASE,
MITOCHONDRIAL)		 3n28 PHOSPHOSERINE
PHOSPHATASE
(Vibrio
cholerae) 		5 / 12 LEU A 104
PHE A 193
LEU A 190
LEU A 305
VAL A  68
 None
 1.12A 2po5A-3n28A:
2.4		 2po5A-3n28A:
23.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PO5_B_CHDB501_0
(FERROCHELATASE,
MITOCHONDRIAL)		 3n28 PHOSPHOSERINE
PHOSPHATASE
(Vibrio
cholerae) 		5 / 11 LEU A 104
PHE A 193
LEU A 190
LEU A 305
VAL A  68
 None
 1.10A 2po5B-3n28A:
2.3		 2po5B-3n28A:
23.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V0M_C_KLNC1498_1
(CYTOCHROME P450 3A4)		 3n28 PHOSPHOSERINE
PHOSPHATASE
(Vibrio
cholerae) 		5 / 12 LEU A  88
ILE A  38
ALA A  96
THR A 298
GLU A 182
 None
 1.26A 2v0mC-3n28A:
undetectable		 2v0mC-3n28A:
23.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DL9_A_V2HA602_0
(CYTOCHROME P450 2R1)		 3n28 PHOSPHOSERINE
PHOSPHATASE
(Vibrio
cholerae) 		5 / 12 THR A 298
VAL A 309
TYR A  95
ILE A 110
THR A 189
 None
 1.12A 3dl9A-3n28A:
undetectable		 3dl9A-3n28A:
22.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EM0_B_CHDB150_0
(ILEAL BILE
ACID-BINDING PROTEIN)		 3n28 PHOSPHOSERINE
PHOSPHATASE
(Vibrio
cholerae) 		5 / 12 THR A 105
VAL A  68
LEU A   9
ILE A  11
THR A   8
 None
 1.18A 3em0B-3n28A:
undetectable		 3em0B-3n28A:
18.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IIL_A_RBFA401_2
(MEMBRANE LIPOPROTEIN
TPN38(B))		 3n28 PHOSPHOSERINE
PHOSPHATASE
(Vibrio
cholerae) 		4 / 8 VAL A 159
ASN A 223
GLN A 120
ILE A 127
 None
 0.91A 4iilA-3n28A:
3.1		 4iilA-3n28A:
23.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O1Z_B_MXMB807_1
(PROSTAGLANDIN G/H
SYNTHASE 1)		 3n28 PHOSPHOSERINE
PHOSPHATASE
(Vibrio
cholerae) 		5 / 12 MET A 180
ILE A 199
VAL A 197
LEU A 112
LEU A 215
 None
 1.11A 4o1zB-3n28A:
undetectable		 4o1zB-3n28A:
20.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CFS_A_TOYA203_1
(AAD(2''),GENTAMICIN
2''-NUCLEOTIDYLTRANS
FERASE,GENTAMICIN
RESISTANCE PROTEIN)		 3n28 PHOSPHOSERINE
PHOSPHATASE
(Vibrio
cholerae) 		4 / 8 ASP A 269
ASP A 113
ASP A 273
ILE A 249
 None
 1.05A 5cfsA-3n28A:
undetectable		 5cfsA-3n28A:
21.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HBS_A_RTLA201_1
(RETINOL-BINDING
PROTEIN 1)		 3n28 PHOSPHOSERINE
PHOSPHATASE
(Vibrio
cholerae) 		4 / 8 LEU A  75
TYR A  95
GLN A  48
MET A  52
 None
 1.15A 5hbsA-3n28A:
undetectable		 5hbsA-3n28A:
21.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BQG_A_ERMA1201_2
(5-HYDROXYTRYPTAMINE
RECEPTOR 2C,SOLUBLE
CYTOCHROME B562)		 3n28 PHOSPHOSERINE
PHOSPHATASE
(Vibrio
cholerae) 		4 / 5 VAL A 267
LEU A 186
VAL A  68
LEU A 104
 None
 0.97A 6bqgA-3n28A:
undetectable		 6bqgA-3n28A:
13.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6D8F_A_ACTA803_0
(UNCHARACTERIZED
PROTEIN)		 3n28 PHOSPHOSERINE
PHOSPHATASE
(Vibrio
cholerae) 		3 / 3 GLU A 167
LEU A 170
ARG A 174
 None
 0.82A 6d8fA-3n28A:
undetectable		 6d8fA-3n28A:
18.70