SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3n29'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YC2_E_NCAE507_0
(NAD-DEPENDENT
DEACETYLASE 2)		 3n29 CARBOXYNORSPERMIDINE
DECARBOXYLASE
(Campylobacter
jejuni) 		4 / 7 ILE A 340
LEU A  18
ASN A 244
ILE A  12
 None
 0.96A 1yc2E-3n29A:
undetectable		 1yc2E-3n29A:
22.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QO4_A_CHDA130_0
(LIVER-BASIC FATTY
ACID BINDING PROTEIN)		 3n29 CARBOXYNORSPERMIDINE
DECARBOXYLASE
(Campylobacter
jejuni) 		5 / 12 LEU A 328
ILE A 252
VAL A 282
THR A 309
MET A 319
 None
 1.29A 2qo4A-3n29A:
undetectable		 2qo4A-3n29A:
13.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BA0_A_HAEA477_1
(MACROPHAGE
METALLOELASTASE)		 3n29 CARBOXYNORSPERMIDINE
DECARBOXYLASE
(Campylobacter
jejuni) 		3 / 3 HIS A  79
GLU A 233
HIS A 164
 None
PLP  A1001 (-3.5A)
PLP  A1001 ( 4.8A)
 0.78A 3ba0A-3n29A:
undetectable		 3ba0A-3n29A:
21.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CR4_X_PNTX101_0
(PROTEIN S100-B)		 3n29 CARBOXYNORSPERMIDINE
DECARBOXYLASE
(Campylobacter
jejuni) 		3 / 3 CYH A 124
HIS A 164
PHE A 165
 None
PLP  A1001 ( 4.8A)
None
 0.95A 3cr4X-3n29A:
undetectable		 3cr4X-3n29A:
13.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3H5G_A_LEIA16_0
(COIL SER L16D-PEN)		 3n29 CARBOXYNORSPERMIDINE
DECARBOXYLASE
(Campylobacter
jejuni) 		4 / 6 LEU A 176
GLU A 177
LYS A 214
LEU A 218
 None
 0.94A 3h5gA-3n29A:
undetectable
3h5gC-3n29A:
undetectable		 3h5gA-3n29A:
8.46
3h5gC-3n29A:
8.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KW4_A_TICA600_1
(CYTOCHROME P450 2B4)		 3n29 CARBOXYNORSPERMIDINE
DECARBOXYLASE
(Campylobacter
jejuni) 		5 / 11 ILE A 353
SER A 265
ILE A 261
VAL A 250
GLY A 310
 None
 0.95A 3kw4A-3n29A:
undetectable		 3kw4A-3n29A:
21.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PS9_A_SAMA670_1
(TRNA
5-METHYLAMINOMETHYL-
2-THIOURIDINE
BIOSYNTHESIS
BIFUNCTIONAL PROTEIN
MNMC)		 3n29 CARBOXYNORSPERMIDINE
DECARBOXYLASE
(Campylobacter
jejuni) 		4 / 6 TYR A 378
GLY A 352
THR A 349
LEU A 355
 None
 0.96A 3ps9A-3n29A:
undetectable		 3ps9A-3n29A:
21.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V4T_A_ACTA502_0
(UDP-N-ACETYLGLUCOSAM
INE
1-CARBOXYVINYLTRANSF
ERASE)		 3n29 CARBOXYNORSPERMIDINE
DECARBOXYLASE
(Campylobacter
jejuni) 		4 / 5 TYR A  81
VAL A 101
GLY A 146
ARG A 123
 None
None
None
PLP  A1001 ( 4.4A)
 1.36A 3v4tA-3n29A:
2.1
3v4tD-3n29A:
2.1		 3v4tA-3n29A:
22.80
3v4tD-3n29A:
22.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A6E_A_SAMA1349_0
(HYDROXYINDOLE
O-METHYLTRANSFERASE)		 3n29 CARBOXYNORSPERMIDINE
DECARBOXYLASE
(Campylobacter
jejuni) 		5 / 12 LEU A  38
GLY A  42
ILE A 344
VAL A 345
ALA A 237
 None
 1.05A 4a6eA-3n29A:
undetectable		 4a6eA-3n29A:
23.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EMA_A_BRLA601_2
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 3n29 CARBOXYNORSPERMIDINE
DECARBOXYLASE
(Campylobacter
jejuni) 		3 / 3 PHE A 304
VAL A 249
ILE A 334
 None
 0.64A 4emaA-3n29A:
undetectable		 4emaA-3n29A:
24.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4GRQ_C_AVLC203_1
(MACROPHAGE MIGRATION
INHIBITORY FACTOR)		 3n29 CARBOXYNORSPERMIDINE
DECARBOXYLASE
(Campylobacter
jejuni) 		4 / 7 PHE A  45
PRO A 356
TYR A  11
PHE A 373
 None
 1.18A 4grqA-3n29A:
undetectable
4grqC-3n29A:
undetectable		 4grqA-3n29A:
15.06
4grqC-3n29A:
15.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4I89_B_1FLB201_1
(TRANSTHYRETIN)		 3n29 CARBOXYNORSPERMIDINE
DECARBOXYLASE
(Campylobacter
jejuni) 		4 / 4 LYS A  68
ALA A  67
SER A  62
THR A  80
 None
 1.47A 4i89B-3n29A:
undetectable		 4i89B-3n29A:
17.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XK8_A_PQNA845_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1)		 3n29 CARBOXYNORSPERMIDINE
DECARBOXYLASE
(Campylobacter
jejuni) 		4 / 8 PHE A 102
ALA A 159
LEU A 120
GLY A 121
 None
 0.95A 4xk8a-3n29A:
undetectable		 4xk8a-3n29A:
19.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5H3A_A_D16A401_1
(ORF70)		 3n29 CARBOXYNORSPERMIDINE
DECARBOXYLASE
(Campylobacter
jejuni) 		4 / 7 PHE A  45
ILE A 340
GLY A  42
PHE A  43
 None
 0.74A 5h3aA-3n29A:
undetectable		 5h3aA-3n29A:
20.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JW1_B_CELB602_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 3n29 CARBOXYNORSPERMIDINE
DECARBOXYLASE
(Campylobacter
jejuni) 		5 / 12 LEU A  56
ALA A  34
GLY A 235
ALA A  39
LEU A  40
 None
None
PLP  A1001 (-3.3A)
PLP  A1001 (-3.3A)
None
 1.02A 5jw1B-3n29A:
undetectable		 5jw1B-3n29A:
22.20