SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3n2b'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ERE_A_ESTA600_1
(ESTROGEN RECEPTOR)		 3n2b DIAMINOPIMELATE
DECARBOXYLASE
(Vibrio
cholerae) 		5 / 9 ALA A 257
LEU A 241
ILE A  56
HIS A  54
LEU A 272
 None
 1.29A 1ereA-3n2bA:
undetectable		 1ereA-3n2bA:
20.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ERE_B_ESTB600_1
(ESTROGEN RECEPTOR)		 3n2b DIAMINOPIMELATE
DECARBOXYLASE
(Vibrio
cholerae) 		5 / 9 ALA A 257
LEU A 241
ILE A  56
HIS A  54
LEU A 272
 None
 1.28A 1ereB-3n2bA:
undetectable		 1ereB-3n2bA:
20.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ERE_C_ESTC600_1
(ESTROGEN RECEPTOR)		 3n2b DIAMINOPIMELATE
DECARBOXYLASE
(Vibrio
cholerae) 		5 / 9 ALA A 257
LEU A 241
ILE A  56
HIS A  54
LEU A 272
 None
 1.28A 1ereC-3n2bA:
undetectable		 1ereC-3n2bA:
20.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ERE_D_ESTD600_1
(ESTROGEN RECEPTOR)		 3n2b DIAMINOPIMELATE
DECARBOXYLASE
(Vibrio
cholerae) 		5 / 9 ALA A 257
LEU A 241
ILE A  56
HIS A  54
LEU A 272
 None
 1.27A 1ereD-3n2bA:
undetectable		 1ereD-3n2bA:
20.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1G50_A_ESTA600_1
(ESTROGEN RECEPTOR)		 3n2b DIAMINOPIMELATE
DECARBOXYLASE
(Vibrio
cholerae) 		5 / 11 ALA A 257
LEU A 241
ILE A  56
HIS A  54
LEU A 272
 None
 1.24A 1g50A-3n2bA:
undetectable		 1g50A-3n2bA:
21.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1PCG_A_ESTA1_1
(ESTROGEN RECEPTOR)		 3n2b DIAMINOPIMELATE
DECARBOXYLASE
(Vibrio
cholerae) 		5 / 10 ALA A 257
LEU A 241
ILE A  56
HIS A  54
LEU A 272
 None
 1.18A 1pcgA-3n2bA:
undetectable		 1pcgA-3n2bA:
21.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QKU_A_ESTA600_1
(ESTRADIOL RECEPTOR)		 3n2b DIAMINOPIMELATE
DECARBOXYLASE
(Vibrio
cholerae) 		5 / 10 ALA A 257
LEU A 241
ILE A  56
HIS A  54
LEU A 272
 None
 1.28A 1qkuA-3n2bA:
undetectable		 1qkuA-3n2bA:
20.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QKU_B_ESTB600_1
(ESTRADIOL RECEPTOR)		 3n2b DIAMINOPIMELATE
DECARBOXYLASE
(Vibrio
cholerae) 		5 / 10 ALA A 257
LEU A 241
ILE A  56
HIS A  54
LEU A 272
 None
 1.27A 1qkuB-3n2bA:
undetectable		 1qkuB-3n2bA:
20.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QKU_C_ESTC600_1
(ESTRADIOL RECEPTOR)		 3n2b DIAMINOPIMELATE
DECARBOXYLASE
(Vibrio
cholerae) 		5 / 10 ALA A 257
LEU A 241
ILE A  56
HIS A  54
LEU A 272
 None
 1.26A 1qkuC-3n2bA:
undetectable		 1qkuC-3n2bA:
20.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DM6_A_IMNA1401_1
(NADP-DEPENDENT
LEUKOTRIENE B4
12-HYDROXYDEHYDROGEN
ASE)		 3n2b DIAMINOPIMELATE
DECARBOXYLASE
(Vibrio
cholerae) 		5 / 10 ILE A 174
ALA A 179
ILE A 147
PRO A 129
GLU A 128
 None
 0.83A 2dm6A-3n2bA:
undetectable
2dm6B-3n2bA:
undetectable		 2dm6A-3n2bA:
21.52
2dm6B-3n2bA:
21.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F9W_A_PAUA6001_0
(PANTOTHENATE KINASE)		 3n2b DIAMINOPIMELATE
DECARBOXYLASE
(Vibrio
cholerae) 		5 / 11 ASN A 310
VAL A 343
GLY A 341
ASP A 348
THR A 289
 None
 1.39A 2f9wA-3n2bA:
undetectable
2f9wB-3n2bA:
undetectable		 2f9wA-3n2bA:
23.95
2f9wB-3n2bA:
23.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NXU_A_RITA600_2
(CYTOCHROME P450 3A4)		 3n2b DIAMINOPIMELATE
DECARBOXYLASE
(Vibrio
cholerae) 		4 / 7 ILE A 325
LEU A  19
THR A  37
THR A  28
 None
 1.26A 3nxuA-3n2bA:
undetectable		 3nxuA-3n2bA:
24.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OU6_C_SAMC300_0
(SAM-DEPENDENT
METHYLTRANSFERASE)		 3n2b DIAMINOPIMELATE
DECARBOXYLASE
(Vibrio
cholerae) 		5 / 12 ALA A 281
GLY A 285
SER A 369
LEU A  38
ALA A  59
 None
 1.28A 3ou6C-3n2bA:
undetectable		 3ou6C-3n2bA:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OU7_C_SAMC300_0
(SAM-DEPENDENT
METHYLTRANSFERASE)		 3n2b DIAMINOPIMELATE
DECARBOXYLASE
(Vibrio
cholerae) 		5 / 12 ALA A 281
GLY A 285
SER A 369
LEU A  38
ALA A  59
 None
 1.30A 3ou7C-3n2bA:
undetectable		 3ou7C-3n2bA:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IOM_A_FOLA608_0
(FORMATE--TETRAHYDROF
OLATE LIGASE)		 3n2b DIAMINOPIMELATE
DECARBOXYLASE
(Vibrio
cholerae) 		4 / 7 ALA A 179
GLU A 228
LEU A 225
LEU A 221
 None
 0.90A 4iomA-3n2bA:
2.7		 4iomA-3n2bA:
23.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JJK_A_FOLA601_0
(FORMATE--TETRAHYDROF
OLATE LIGASE)		 3n2b DIAMINOPIMELATE
DECARBOXYLASE
(Vibrio
cholerae) 		4 / 8 ALA A 179
GLU A 228
LEU A 225
LEU A 221
 None
 0.91A 4jjkA-3n2bA:
3.1		 4jjkA-3n2bA:
23.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LTW_A_STRA301_1
(ANCESTRAL STEROID
RECEPTOR 2)		 3n2b DIAMINOPIMELATE
DECARBOXYLASE
(Vibrio
cholerae) 		5 / 12 LEU A  66
LEU A  69
ASN A  70
LEU A  72
ALA A  73
 None
 1.10A 4ltwA-3n2bA:
undetectable		 4ltwA-3n2bA:
19.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PXM_B_ESTB2000_1
(ESTROGEN RECEPTOR)		 3n2b DIAMINOPIMELATE
DECARBOXYLASE
(Vibrio
cholerae) 		5 / 11 ALA A 257
LEU A 241
ILE A  56
HIS A  54
LEU A 272
 None
 1.23A 4pxmB-3n2bA:
undetectable		 4pxmB-3n2bA:
23.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XQG_A_AG2A505_1
(HOMOSPERMIDINE
SYNTHASE)		 3n2b DIAMINOPIMELATE
DECARBOXYLASE
(Vibrio
cholerae) 		4 / 8 ARG A 168
ASP A 177
PHE A 176
ASP A 154
 None
 1.08A 4xqgA-3n2bA:
undetectable		 4xqgA-3n2bA:
23.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XQG_B_AG2B505_1
(HOMOSPERMIDINE
SYNTHASE)		 3n2b DIAMINOPIMELATE
DECARBOXYLASE
(Vibrio
cholerae) 		4 / 8 ARG A 168
ASP A 177
PHE A 176
ASP A 154
 None
 1.10A 4xqgB-3n2bA:
undetectable		 4xqgB-3n2bA:
23.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YBN_A_ACTA303_0
(FLAVIN-NUCLEOTIDE-BI
NDING PROTEIN)		 3n2b DIAMINOPIMELATE
DECARBOXYLASE
(Vibrio
cholerae) 		3 / 3 VAL A 194
TYR A 183
ALA A 186
 None
 0.55A 4ybnA-3n2bA:
undetectable		 4ybnA-3n2bA:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z69_A_DIFA1006_1
(SERUM ALBUMIN)		 3n2b DIAMINOPIMELATE
DECARBOXYLASE
(Vibrio
cholerae) 		4 / 7 ILE A 305
LEU A 364
GLY A 351
LYS A 352
 None
 1.05A 4z69A-3n2bA:
undetectable		 4z69A-3n2bA:
22.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DXB_B_ESTB601_1
(ESTROGEN RECEPTOR)		 3n2b DIAMINOPIMELATE
DECARBOXYLASE
(Vibrio
cholerae) 		5 / 11 ALA A 257
LEU A 241
ILE A  56
HIS A  54
LEU A 272
 None
 1.18A 5dxbB-3n2bA:
undetectable		 5dxbB-3n2bA:
20.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M50_E_TA1E502_1
(TUBULIN BETA-2B
CHAIN)		 3n2b DIAMINOPIMELATE
DECARBOXYLASE
(Vibrio
cholerae) 		5 / 12 ASP A  80
LEU A 218
THR A 215
GLY A 240
LEU A 241
 None
 1.34A 5m50E-3n2bA:
2.1		 5m50E-3n2bA:
22.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CBZ_B_ESTB602_1
(ESTROGEN RECEPTOR)		 3n2b DIAMINOPIMELATE
DECARBOXYLASE
(Vibrio
cholerae) 		5 / 10 ALA A 257
LEU A 241
ILE A  56
HIS A  54
LEU A 272
 None
 1.20A 6cbzB-3n2bA:
undetectable		 6cbzB-3n2bA:
10.46