SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3n2e'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1D1G_A_MTXA171_1
(DIHYDROFOLATE
REDUCTASE)		 3n2e SHIKIMATE KINASE
(Helicobacter
pylori) 		5 / 12 ILE A  35
ARG A  39
LEU A  63
ILE A  76
THR A  72
 None
 1.16A 1d1gA-3n2eA:
undetectable		 1d1gA-3n2eA:
21.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KVL_A_CLSA371_1
(BETA-LACTAMASE)		 3n2e SHIKIMATE KINASE
(Helicobacter
pylori) 		5 / 10 GLY A  80
LEU A 135
TYR A 136
THR A  78
GLY A  79
 OSA  A1001 (-3.3A)
OSA  A1001 (-3.5A)
OSA  A1001 (-4.8A)
None
None
 1.11A 1kvlA-3n2eA:
undetectable		 1kvlA-3n2eA:
18.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VFT_A_SORA1419_0
(XYLITOL OXIDASE)		 3n2e SHIKIMATE KINASE
(Helicobacter
pylori) 		5 / 12 HIS A  85
THR A  32
GLU A  60
ARG A  57
THR A  78
 None
None
None
OSA  A1001 (-3.9A)
None
 1.27A 2vftA-3n2eA:
0.0		 2vftA-3n2eA:
18.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZW9_B_SAMB801_1
(LEUCINE CARBOXYL
METHYLTRANSFERASE 2)		 3n2e SHIKIMATE KINASE
(Helicobacter
pylori) 		4 / 8 ILE A  82
SER A  12
ASP A  33
SER A  77
 None
 0.99A 2zw9B-3n2eA:
undetectable		 2zw9B-3n2eA:
11.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EIG_A_MTXA200_1
(DIHYDROFOLATE
REDUCTASE)		 3n2e SHIKIMATE KINASE
(Helicobacter
pylori) 		5 / 12 ILE A  76
ALA A  18
LEU A  97
GLU A  60
LEU A  88
 None
 1.25A 3eigA-3n2eA:
undetectable		 3eigA-3n2eA:
22.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FW1_A_STIA233_1
(RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE
[QUINONE])		 3n2e SHIKIMATE KINASE
(Helicobacter
pylori) 		5 / 10 PHE A  48
GLY A  80
GLY A  79
THR A  78
ILE A   7
 OSA  A1001 (-4.1A)
OSA  A1001 (-3.3A)
None
None
None
 1.35A 3fw1A-3n2eA:
undetectable		 3fw1A-3n2eA:
23.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U52_A_CUA515_0
(PHENOL HYDROXYLASE
COMPONENT PHL
PHENOL HYDROXYLASE
COMPONENT PHN)		 3n2e SHIKIMATE KINASE
(Helicobacter
pylori) 		3 / 3 HIS A  74
HIS A   3
ILE A  76
 None
 0.77A 3u52A-3n2eA:
undetectable
3u52C-3n2eA:
undetectable		 3u52A-3n2eA:
16.14
3u52C-3n2eA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OG9_B_TESB502_1
(-)		 3n2e SHIKIMATE KINASE
(Helicobacter
pylori) 		5 / 12 LEU A   6
LEU A  17
ILE A 161
ALA A  24
LEU A  27
 None
 1.06A 5og9B-3n2eA:
undetectable		 5og9B-3n2eA:
16.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5U63_A_ACTA405_0
(THIOREDOXIN
REDUCTASE)		 3n2e SHIKIMATE KINASE
(Helicobacter
pylori) 		3 / 3 GLY A  92
LEU A  91
HIS A   3
 None
 0.58A 5u63A-3n2eA:
2.4		 5u63A-3n2eA:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5U63_B_ACTB405_0
(THIOREDOXIN
REDUCTASE)		 3n2e SHIKIMATE KINASE
(Helicobacter
pylori) 		3 / 3 GLY A  92
LEU A  91
HIS A   3
 None
 0.56A 5u63B-3n2eA:
2.1		 5u63B-3n2eA:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5V5Z_A_1YNA602_1
(LANOSTEROL 14-ALPHA
DEMETHYLASE)		 3n2e SHIKIMATE KINASE
(Helicobacter
pylori) 		5 / 12 PHE A  56
ILE A  36
GLY A  79
LEU A  88
MET A  84
 None
None
None
None
OSA  A1001 (-4.6A)
 1.22A 5v5zA-3n2eA:
undetectable		 5v5zA-3n2eA:
16.21