SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3n2l'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BGD_A_PM6A301_1
(THIOPURINE
S-METHYLTRANSFERASE)		 3n2l OROTATE
PHOSPHORIBOSYLTRANSF
ERASE
(Vibrio
cholerae) 		4 / 6 PHE A  98
GLY A  75
ALA A  79
LEU A 123
 None
 0.94A 3bgdA-3n2lA:
2.1		 3bgdA-3n2lA:
24.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PS9_A_SAMA670_0
(TRNA
5-METHYLAMINOMETHYL-
2-THIOURIDINE
BIOSYNTHESIS
BIFUNCTIONAL PROTEIN
MNMC)		 3n2l OROTATE
PHOSPHORIBOSYLTRANSF
ERASE
(Vibrio
cholerae) 		5 / 12 PHE A   9
GLY A  51
PHE A  41
ILE A  78
PHE A  53
 None
 1.37A 3ps9A-3n2lA:
undetectable		 3ps9A-3n2lA:
16.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DUB_B_LDPB501_1
(CYTOCHROME P450 BM3
VARIANT 9D7)		 3n2l OROTATE
PHOSPHORIBOSYLTRANSF
ERASE
(Vibrio
cholerae) 		4 / 6 ALA A  83
GLY A  70
PRO A  71
VAL A 124
 None
 0.94A 4dubB-3n2lA:
undetectable		 4dubB-3n2lA:
20.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EMA_A_BRLA601_2
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 3n2l OROTATE
PHOSPHORIBOSYLTRANSF
ERASE
(Vibrio
cholerae) 		3 / 3 PHE A  35
VAL A 183
ILE A  10
 None
 0.61A 4emaA-3n2lA:
undetectable		 4emaA-3n2lA:
22.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZJI_A_PQNA844_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1
PHOTOSYSTEM I
REACTION CENTER
SUBUNIT IX)		 3n2l OROTATE
PHOSPHORIBOSYLTRANSF
ERASE
(Vibrio
cholerae) 		5 / 10 GLY A 119
ILE A  63
ALA A 149
LEU A 148
PHE A  36
 None
 1.17A 5zjiA-3n2lA:
undetectable
5zjiJ-3n2lA:
undetectable		 5zjiA-3n2lA:
16.74
5zjiJ-3n2lA:
10.50