SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3n2n'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JTX_A_CVIA200_0
(HYPOTHETICAL
TRANSCRIPTIONAL
REGULATOR IN QACA
5'REGION)		 3n2n ANTHRAX TOXIN
RECEPTOR 1
(Homo
sapiens) 		6 / 12 THR F 141
ILE F 212
ILE F 211
TYR F  46
ILE F  83
ALA F 127
 None
 1.30A 1jtxA-3n2nF:
undetectable		 1jtxA-3n2nF:
23.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1L2I_B_CCSB417_0
(ESTROGEN RECEPTOR)		 3n2n ANTHRAX TOXIN
RECEPTOR 1
(Homo
sapiens) 		4 / 6 PHE F 205
GLU F  61
GLN F 206
VAL F 201
 None
 1.29A 1l2iB-3n2nF:
undetectable		 1l2iB-3n2nF:
19.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BJF_A_DXCA330_0
(CHOLOYLGLYCINE
HYDROLASE)		 3n2n ANTHRAX TOXIN
RECEPTOR 1
(Homo
sapiens) 		5 / 12 PHE F  82
ALA F  70
ILE F 146
ILE F 145
LEU F  78
 None
 1.19A 2bjfA-3n2nF:
undetectable		 2bjfA-3n2nF:
19.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K4Y_A_ACTA502_0
(RNA-DEPENDENT RNA
POLYMERASE)		 3n2n ANTHRAX TOXIN
RECEPTOR 1
(Homo
sapiens) 		4 / 5 LYS F 111
LEU F 109
GLU F 108
LEU F  92
 None
None
None
ACT  F 224 ( 4.7A)
 1.33A 4k4yA-3n2nF:
undetectable		 4k4yA-3n2nF:
17.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K4Y_E_ACTE503_0
(RNA-DEPENDENT RNA
POLYMERASE)		 3n2n ANTHRAX TOXIN
RECEPTOR 1
(Homo
sapiens) 		4 / 4 LYS F 111
LEU F 109
GLU F 108
LEU F  92
 None
None
None
ACT  F 224 ( 4.7A)
 1.34A 4k4yE-3n2nF:
undetectable		 4k4yE-3n2nF:
17.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K4Y_I_ACTI503_0
(RNA-DEPENDENT RNA
POLYMERASE)		 3n2n ANTHRAX TOXIN
RECEPTOR 1
(Homo
sapiens) 		4 / 5 LYS F 111
LEU F 109
GLU F 108
LEU F  92
 None
None
None
ACT  F 224 ( 4.7A)
 1.30A 4k4yI-3n2nF:
undetectable		 4k4yI-3n2nF:
17.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OLT_A_GCSA303_1
(CHITOSANASE)		 3n2n ANTHRAX TOXIN
RECEPTOR 1
(Homo
sapiens) 		4 / 6 ILE F 174
ASP F 193
ARG F 169
GLY F 172
 None
 1.03A 4oltA-3n2nF:
1.2		 4oltA-3n2nF:
23.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OLT_B_GCSB303_1
(CHITOSANASE)		 3n2n ANTHRAX TOXIN
RECEPTOR 1
(Homo
sapiens) 		4 / 6 ILE F 174
ASP F 193
ARG F 169
GLY F 172
 None
 1.04A 4oltB-3n2nF:
undetectable		 4oltB-3n2nF:
23.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VCY_A_DB8A401_2
(MEMBRANE-ASSOCIATED
TYROSINE- AND
THREONINE-SPECIFIC
CDC2-INHIBITORY
KINASE)		 3n2n ANTHRAX TOXIN
RECEPTOR 1
(Homo
sapiens) 		4 / 4 VAL F 178
LEU F  69
ASN F 202
ASP F 203
 None
 1.37A 5vcyA-3n2nF:
undetectable		 5vcyA-3n2nF:
19.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Y7P_B_CHDB401_0
(BILE SALT HYDROLASE)		 3n2n ANTHRAX TOXIN
RECEPTOR 1
(Homo
sapiens) 		5 / 10 LEU F 153
LEU F  49
PHE F  85
PHE F  47
ALA F 177
 None
 1.13A 5y7pB-3n2nF:
undetectable		 5y7pB-3n2nF:
20.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Y7P_D_CHDD401_0
(BILE SALT HYDROLASE)		 3n2n ANTHRAX TOXIN
RECEPTOR 1
(Homo
sapiens) 		5 / 10 LEU F 153
LEU F  49
PHE F  85
PHE F  47
ALA F 177
 None
 1.15A 5y7pD-3n2nF:
undetectable		 5y7pD-3n2nF:
20.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Y7P_H_CHDH401_0
(BILE SALT HYDROLASE)		 3n2n ANTHRAX TOXIN
RECEPTOR 1
(Homo
sapiens) 		5 / 10 LEU F 153
LEU F  49
PHE F  85
PHE F  47
ALA F 177
 None
 1.13A 5y7pH-3n2nF:
undetectable		 5y7pH-3n2nF:
20.06