SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3n2o'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1AV2_B_DVAB8_0
(GRAMICIDIN A)		 3n2o BIOSYNTHETIC
ARGININE
DECARBOXYLASE
(Vibrio
vulnificus) 		3 / 3 VAL A 521
VAL A 490
TRP A  23
 None
 0.99A 1av2A-3n2oA:
undetectable
1av2B-3n2oA:
undetectable		 1av2A-3n2oA:
3.11
1av2B-3n2oA:
3.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1D4Y_A_TPVA501_2
(PROTEIN (HIV-1
PROTEASE))		 3n2o BIOSYNTHETIC
ARGININE
DECARBOXYLASE
(Vibrio
vulnificus) 		4 / 8 LEU A  99
GLY A 203
VAL A 339
ILE A 341
 None
 0.56A 1d4yB-3n2oA:
undetectable		 1d4yB-3n2oA:
9.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HXW_B_RITB301_2
(HIV-1 PROTEASE)		 3n2o BIOSYNTHETIC
ARGININE
DECARBOXYLASE
(Vibrio
vulnificus) 		5 / 11 LEU A 530
GLY A 523
ILE A  30
PRO A 533
VAL A 532
 None
 0.96A 1hxwB-3n2oA:
undetectable		 1hxwB-3n2oA:
10.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1N13_B_AG2B7011_1
(PYRUVOYL-DEPENDENT
ARGININE
DECARBOXYLASE ALPHA
CHAIN
PYRUVOYL-DEPENDENT
ARGININE
DECARBOXYLASE BETA
CHAIN)		 3n2o BIOSYNTHETIC
ARGININE
DECARBOXYLASE
(Vibrio
vulnificus) 		4 / 5 GLU A 192
ARG A 239
LEU A 188
ASP A 187
 None
 1.20A 1n13B-3n2oA:
0.3
1n13C-3n2oA:
undetectable		 1n13B-3n2oA:
9.58
1n13C-3n2oA:
6.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1T88_A_CAMA1422_0
(CYTOCHROME P450-CAM)		 3n2o BIOSYNTHETIC
ARGININE
DECARBOXYLASE
(Vibrio
vulnificus) 		4 / 7 PHE A  85
TYR A  98
VAL A 292
GLY A 293
 None
None
None
PLP  A1001 ( 4.3A)
 0.88A 1t88A-3n2oA:
undetectable		 1t88A-3n2oA:
20.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1W5U_B_DVAB8_0
(GRAMICIDIN D)		 3n2o BIOSYNTHETIC
ARGININE
DECARBOXYLASE
(Vibrio
vulnificus) 		3 / 3 VAL A 521
VAL A 490
TRP A  23
 None
 0.97A 1w5uA-3n2oA:
undetectable
1w5uB-3n2oA:
undetectable		 1w5uA-3n2oA:
3.11
1w5uB-3n2oA:
3.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A1M_A_CAMA1422_0
(CYTOCHROME P450-CAM)		 3n2o BIOSYNTHETIC
ARGININE
DECARBOXYLASE
(Vibrio
vulnificus) 		4 / 7 PHE A  85
TYR A  98
VAL A 292
GLY A 293
 None
None
None
PLP  A1001 ( 4.3A)
 0.85A 2a1mA-3n2oA:
undetectable		 2a1mA-3n2oA:
20.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A1O_A_CAMA1422_0
(CYTOCHROME P450-CAM)		 3n2o BIOSYNTHETIC
ARGININE
DECARBOXYLASE
(Vibrio
vulnificus) 		4 / 8 PHE A  85
TYR A  98
VAL A 292
GLY A 293
 None
None
None
PLP  A1001 ( 4.3A)
 0.84A 2a1oA-3n2oA:
undetectable		 2a1oA-3n2oA:
20.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A58_A_RBFA300_1
(6,7-DIMETHYL-8-RIBIT
YLLUMAZINE SYNTHASE)		 3n2o BIOSYNTHETIC
ARGININE
DECARBOXYLASE
(Vibrio
vulnificus) 		5 / 11 TYR A 102
GLY A 345
SER A 344
LEU A 100
ALA A 550
 None
PLP  A1001 (-3.3A)
None
None
None
 1.17A 2a58A-3n2oA:
2.9
2a58E-3n2oA:
undetectable		 2a58A-3n2oA:
15.30
2a58E-3n2oA:
15.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A58_B_RBFB301_1
(6,7-DIMETHYL-8-RIBIT
YLLUMAZINE SYNTHASE)		 3n2o BIOSYNTHETIC
ARGININE
DECARBOXYLASE
(Vibrio
vulnificus) 		5 / 12 ALA A 550
TYR A 102
GLY A 345
SER A 344
LEU A 100
 None
None
PLP  A1001 (-3.3A)
None
None
 1.17A 2a58A-3n2oA:
2.9
2a58B-3n2oA:
2.9		 2a58A-3n2oA:
15.30
2a58B-3n2oA:
15.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A58_C_RBFC302_1
(6,7-DIMETHYL-8-RIBIT
YLLUMAZINE SYNTHASE)		 3n2o BIOSYNTHETIC
ARGININE
DECARBOXYLASE
(Vibrio
vulnificus) 		5 / 12 ALA A 550
TYR A 102
GLY A 345
SER A 344
LEU A 100
 None
None
PLP  A1001 (-3.3A)
None
None
 1.17A 2a58B-3n2oA:
2.9
2a58C-3n2oA:
2.8		 2a58B-3n2oA:
15.30
2a58C-3n2oA:
15.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A58_D_RBFD303_1
(6,7-DIMETHYL-8-RIBIT
YLLUMAZINE SYNTHASE)		 3n2o BIOSYNTHETIC
ARGININE
DECARBOXYLASE
(Vibrio
vulnificus) 		5 / 11 ALA A 550
TYR A 102
GLY A 345
SER A 344
LEU A 100
 None
None
PLP  A1001 (-3.3A)
None
None
 1.17A 2a58C-3n2oA:
2.8
2a58D-3n2oA:
undetectable		 2a58C-3n2oA:
15.30
2a58D-3n2oA:
15.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A58_E_RBFE304_1
(6,7-DIMETHYL-8-RIBIT
YLLUMAZINE SYNTHASE)		 3n2o BIOSYNTHETIC
ARGININE
DECARBOXYLASE
(Vibrio
vulnificus) 		5 / 12 ALA A 550
TYR A 102
GLY A 345
SER A 344
LEU A 100
 None
None
PLP  A1001 (-3.3A)
None
None
 1.17A 2a58D-3n2oA:
undetectable
2a58E-3n2oA:
undetectable		 2a58D-3n2oA:
15.30
2a58E-3n2oA:
15.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2IZQ_C_DVAC8_0
(GRAMICIDIN D)		 3n2o BIOSYNTHETIC
ARGININE
DECARBOXYLASE
(Vibrio
vulnificus) 		3 / 3 VAL A 490
TRP A  23
VAL A 521
 None
 0.99A 2izqC-3n2oA:
undetectable
2izqD-3n2oA:
undetectable		 2izqC-3n2oA:
3.11
2izqD-3n2oA:
3.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NNK_A_ROCA401_3
(PROTEASE)		 3n2o BIOSYNTHETIC
ARGININE
DECARBOXYLASE
(Vibrio
vulnificus) 		5 / 12 LEU A 530
GLY A 523
ILE A  30
PRO A 533
VAL A 532
 None
 0.87A 2nnkB-3n2oA:
undetectable		 2nnkB-3n2oA:
10.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K37_B_BCZB468_1
(NEURAMINIDASE)		 3n2o BIOSYNTHETIC
ARGININE
DECARBOXYLASE
(Vibrio
vulnificus) 		3 / 3 ARG A 205
GLU A 131
TYR A 162
 PLP  A1001 ( 4.6A)
PLP  A1001 ( 4.4A)
None
 0.85A 3k37B-3n2oA:
undetectable		 3k37B-3n2oA:
20.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KMO_B_EAAB213_1
(GLUTATHIONE
S-TRANSFERASE P)		 3n2o BIOSYNTHETIC
ARGININE
DECARBOXYLASE
(Vibrio
vulnificus) 		4 / 7 TYR A 277
PHE A 290
VAL A 292
ASN A  96
 None
 1.06A 3kmoB-3n2oA:
undetectable		 3kmoB-3n2oA:
17.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N58_C_ADNC500_2
(ADENOSYLHOMOCYSTEINA
SE)		 3n2o BIOSYNTHETIC
ARGININE
DECARBOXYLASE
(Vibrio
vulnificus) 		4 / 5 LEU A  67
GLN A 476
THR A 565
HIS A 352
 None
 1.46A 3n58C-3n2oA:
undetectable		 3n58C-3n2oA:
21.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NDT_D_ROCD100_1
(PROTEASE)		 3n2o BIOSYNTHETIC
ARGININE
DECARBOXYLASE
(Vibrio
vulnificus) 		5 / 12 LEU A 530
GLY A 523
ILE A  30
PRO A 533
VAL A 532
 None
 0.92A 3ndtC-3n2oA:
undetectable		 3ndtC-3n2oA:
9.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NDU_D_ROCD100_1
(PROTEASE)		 3n2o BIOSYNTHETIC
ARGININE
DECARBOXYLASE
(Vibrio
vulnificus) 		5 / 12 LEU A 530
GLY A 523
ILE A  30
PRO A 533
VAL A 532
 None
 0.92A 3nduC-3n2oA:
undetectable		 3nduC-3n2oA:
9.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NXU_A_RITA600_2
(CYTOCHROME P450 3A4)		 3n2o BIOSYNTHETIC
ARGININE
DECARBOXYLASE
(Vibrio
vulnificus) 		4 / 7 PHE A  85
ILE A 206
LEU A 256
THR A 325
 None
 1.19A 3nxuA-3n2oA:
undetectable		 3nxuA-3n2oA:
21.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3T7S_B_SAMB300_0
(PUTATIVE
METHYLTRANSFERASE)		 3n2o BIOSYNTHETIC
ARGININE
DECARBOXYLASE
(Vibrio
vulnificus) 		5 / 12 GLN A 476
GLY A 586
GLY A 563
ASP A 587
ASN A 584
 None
 1.28A 3t7sB-3n2oA:
undetectable		 3t7sB-3n2oA:
16.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4F4D_A_CHDA506_0
(FERROCHELATASE,
MITOCHONDRIAL)		 3n2o BIOSYNTHETIC
ARGININE
DECARBOXYLASE
(Vibrio
vulnificus) 		4 / 4 PRO A 489
LEU A 547
ILE A 298
ARG A  77
 None
 1.05A 4f4dA-3n2oA:
undetectable		 4f4dA-3n2oA:
20.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O1Z_A_MXMA807_1
(PROSTAGLANDIN G/H
SYNTHASE 1)		 3n2o BIOSYNTHETIC
ARGININE
DECARBOXYLASE
(Vibrio
vulnificus) 		5 / 12 ILE A  81
LEU A  74
GLY A 549
ALA A 350
LEU A 296
 None
 0.97A 4o1zA-3n2oA:
undetectable		 4o1zA-3n2oA:
20.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QOG_B_ML1B302_1
(RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE
[QUINONE])		 3n2o BIOSYNTHETIC
ARGININE
DECARBOXYLASE
(Vibrio
vulnificus) 		4 / 6 GLY A 327
PHE A 290
ILE A 322
PHE A 254
 None
 1.08A 4qogA-3n2oA:
undetectable
4qogB-3n2oA:
undetectable		 4qogA-3n2oA:
15.77
4qogB-3n2oA:
15.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UAC_A_ACRA501_2
(CARBOHYDRATE ABC
TRANSPORTER
SUBSTRATE-BINDING
PROTEIN, CUT1 FAMILY
(TC 3.A.1.1.-))		 3n2o BIOSYNTHETIC
ARGININE
DECARBOXYLASE
(Vibrio
vulnificus) 		4 / 7 PRO A 540
GLU A 539
SER A  51
GLU A  35
 None
 1.31A 4uacA-3n2oA:
undetectable		 4uacA-3n2oA:
20.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Y8W_C_STRC603_2
(CYTOCHROME P450
21-HYDROXYLASE)		 3n2o BIOSYNTHETIC
ARGININE
DECARBOXYLASE
(Vibrio
vulnificus) 		3 / 3 LEU A 128
VAL A 113
ASP A 114
 None
 0.56A 4y8wC-3n2oA:
undetectable		 4y8wC-3n2oA:
22.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z91_E_4LEE401_1
(GAMMA-AMINOBUTYRIC-A
CID RECEPTOR SUBUNIT
BETA-1)		 3n2o BIOSYNTHETIC
ARGININE
DECARBOXYLASE
(Vibrio
vulnificus) 		5 / 10 LEU A 180
THR A 248
LEU A 249
LEU A 240
LEU A 186
 None
 1.05A 4z91A-3n2oA:
5.1
4z91B-3n2oA:
5.2
4z91C-3n2oA:
5.3
4z91D-3n2oA:
5.3
4z91E-3n2oA:
5.2		 4z91A-3n2oA:
19.08
4z91B-3n2oA:
19.08
4z91C-3n2oA:
19.08
4z91D-3n2oA:
19.08
4z91E-3n2oA:
19.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z91_E_4LEE401_1
(GAMMA-AMINOBUTYRIC-A
CID RECEPTOR SUBUNIT
BETA-1)		 3n2o BIOSYNTHETIC
ARGININE
DECARBOXYLASE
(Vibrio
vulnificus) 		5 / 10 THR A 248
LEU A 249
LEU A 240
LEU A 186
LEU A 180
 None
 0.99A 4z91A-3n2oA:
5.1
4z91B-3n2oA:
5.2
4z91C-3n2oA:
5.3
4z91D-3n2oA:
5.3
4z91E-3n2oA:
5.2		 4z91A-3n2oA:
19.08
4z91B-3n2oA:
19.08
4z91C-3n2oA:
19.08
4z91D-3n2oA:
19.08
4z91E-3n2oA:
19.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z91_E_4LEE401_1
(GAMMA-AMINOBUTYRIC-A
CID RECEPTOR SUBUNIT
BETA-1)		 3n2o BIOSYNTHETIC
ARGININE
DECARBOXYLASE
(Vibrio
vulnificus) 		5 / 10 THR A 248
LEU A 249
LEU A 240
LEU A 186
LEU A 180
 None
 1.03A 4z91A-3n2oA:
5.1
4z91B-3n2oA:
5.2
4z91C-3n2oA:
5.3
4z91D-3n2oA:
5.3
4z91E-3n2oA:
5.2		 4z91A-3n2oA:
19.08
4z91B-3n2oA:
19.08
4z91C-3n2oA:
19.08
4z91D-3n2oA:
19.08
4z91E-3n2oA:
19.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5E26_A_PAUA602_0
(PANTOTHENATE KINASE
2, MITOCHONDRIAL)		 3n2o BIOSYNTHETIC
ARGININE
DECARBOXYLASE
(Vibrio
vulnificus) 		4 / 7 GLY A 295
SER A 344
GLY A 345
ALA A 297
 PLP  A1001 (-3.4A)
None
PLP  A1001 (-3.3A)
None
 0.77A 5e26A-3n2oA:
undetectable
5e26B-3n2oA:
4.0		 5e26A-3n2oA:
21.05
5e26B-3n2oA:
21.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5E26_B_PAUB601_0
(PANTOTHENATE KINASE
2, MITOCHONDRIAL)		 3n2o BIOSYNTHETIC
ARGININE
DECARBOXYLASE
(Vibrio
vulnificus) 		4 / 7 ALA A 297
GLY A 295
SER A 344
GLY A 345
 None
PLP  A1001 (-3.4A)
None
PLP  A1001 (-3.3A)
 0.83A 5e26A-3n2oA:
undetectable
5e26B-3n2oA:
4.0		 5e26A-3n2oA:
21.05
5e26B-3n2oA:
21.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5E26_C_PAUC602_0
(PANTOTHENATE KINASE
2, MITOCHONDRIAL)		 3n2o BIOSYNTHETIC
ARGININE
DECARBOXYLASE
(Vibrio
vulnificus) 		4 / 7 GLY A 295
SER A 344
GLY A 345
ALA A 297
 PLP  A1001 (-3.4A)
None
PLP  A1001 (-3.3A)
None
 0.79A 5e26C-3n2oA:
3.3
5e26D-3n2oA:
2.3		 5e26C-3n2oA:
21.05
5e26D-3n2oA:
21.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5E26_D_PAUD601_0
(PANTOTHENATE KINASE
2, MITOCHONDRIAL)		 3n2o BIOSYNTHETIC
ARGININE
DECARBOXYLASE
(Vibrio
vulnificus) 		4 / 8 ALA A 297
GLY A 295
SER A 344
GLY A 345
 None
PLP  A1001 (-3.4A)
None
PLP  A1001 (-3.3A)
 0.80A 5e26C-3n2oA:
3.3
5e26D-3n2oA:
2.3		 5e26C-3n2oA:
21.05
5e26D-3n2oA:
21.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5G44_A_YTZA1512_1
(NUCLEAR RECEPTOR
ROR-GAMMA)		 3n2o BIOSYNTHETIC
ARGININE
DECARBOXYLASE
(Vibrio
vulnificus) 		5 / 9 GLN A 127
LEU A 128
LEU A 117
VAL A 176
ALA A 145
 None
 1.48A 5g44A-3n2oA:
undetectable		 5g44A-3n2oA:
18.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5GSN_A_MMZA503_1
(FLAVIN-CONTAINING
MONOOXYGENASE)		 3n2o BIOSYNTHETIC
ARGININE
DECARBOXYLASE
(Vibrio
vulnificus) 		3 / 3 ASN A 235
SER A 231
SER A 229
 None
 0.70A 5gsnA-3n2oA:
undetectable		 5gsnA-3n2oA:
21.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M5K_B_ADNB502_2
(ADENOSYLHOMOCYSTEINA
SE)		 3n2o BIOSYNTHETIC
ARGININE
DECARBOXYLASE
(Vibrio
vulnificus) 		4 / 4 GLN A 408
THR A 407
LEU A 457
LEU A 460
 None
 1.24A 5m5kB-3n2oA:
undetectable		 5m5kB-3n2oA:
22.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TRQ_B_ACTB307_0
(WELO5)		 3n2o BIOSYNTHETIC
ARGININE
DECARBOXYLASE
(Vibrio
vulnificus) 		3 / 3 GLU A 170
HIS A 174
VAL A 176
 None
 0.84A 5trqB-3n2oA:
undetectable		 5trqB-3n2oA:
18.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WYQ_A_SAMA401_1
(TRNA
(GUANINE-N(1)-)-METH
YLTRANSFERASE)		 3n2o BIOSYNTHETIC
ARGININE
DECARBOXYLASE
(Vibrio
vulnificus) 		4 / 4 ASP A 514
SER A 513
ASP A 512
HIS A 559
 None
AG2  A1002 (-3.1A)
AG2  A1002 (-3.2A)
None
 1.32A 5wyqB-3n2oA:
1.3		 5wyqB-3n2oA:
18.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BRD_A_RFPA502_2
(RIFAMPIN
MONOOXYGENASE)		 3n2o BIOSYNTHETIC
ARGININE
DECARBOXYLASE
(Vibrio
vulnificus) 		4 / 4 GLN A  25
VAL A  20
ARG A  69
ARG A  77
 None
 1.40A 6brdA-3n2oA:
undetectable		 6brdA-3n2oA:
8.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EKZ_A_SNPA414_0
(AROMATIC
PEROXYGENASE)		 3n2o BIOSYNTHETIC
ARGININE
DECARBOXYLASE
(Vibrio
vulnificus) 		4 / 5 PHE A 546
VAL A 359
MET A  36
VAL A 354
 None
 1.37A 6ekzA-3n2oA:
undetectable		 6ekzA-3n2oA:
7.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GNG_B_QPSB601_3
(-)		 3n2o BIOSYNTHETIC
ARGININE
DECARBOXYLASE
(Vibrio
vulnificus) 		3 / 3 ASP A 601
ASP A 591
ASN A 584
 None
 0.83A 6gngB-3n2oA:
undetectable		 6gngB-3n2oA:
21.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6JMJ_A_ASCA201_0
(PHOSPHOPANTETHEINE
ADENYLYLTRANSFERASE)		 3n2o BIOSYNTHETIC
ARGININE
DECARBOXYLASE
(Vibrio
vulnificus) 		4 / 5 GLY A 302
THR A 303
SER A 308
SER A 307
 None
 1.11A 6jmjA-3n2oA:
undetectable		 6jmjA-3n2oA:
14.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NQA_K_SAMK500_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE,
H3 LYSINE-79
SPECIFIC)		 3n2o BIOSYNTHETIC
ARGININE
DECARBOXYLASE
(Vibrio
vulnificus) 		5 / 10 GLY A 495
GLY A  34
VAL A  14
GLU A  35
ASN A 498
 None
 1.29A 6nqaK-3n2oA:
undetectable		 6nqaK-3n2oA:
20.18