SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3n2q'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JTX_A_CVIA200_0
(HYPOTHETICAL
TRANSCRIPTIONAL
REGULATOR IN QACA
5'REGION)		 3n2q SEX PHEROMONE
STAPH-CAM373
(Bacillus
cereus) 		5 / 12 ILE A 189
ILE A 204
ILE A  64
ALA A  67
ASN A  68
 None
 1.05A 1jtxA-3n2qA:
undetectable		 1jtxA-3n2qA:
22.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YC2_B_NCAB508_0
(NAD-DEPENDENT
DEACETYLASE 2)		 3n2q SEX PHEROMONE
STAPH-CAM373
(Bacillus
cereus) 		4 / 5 GLN A 128
LEU A  84
GLN A  91
TYR A 130
 None
 1.48A 1yc2B-3n2qA:
undetectable
1yc2C-3n2qA:
undetectable		 1yc2B-3n2qA:
19.54
1yc2C-3n2qA:
19.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YGN_A_PCFA1179_0
(WNT INHIBITORY
FACTOR 1)		 3n2q SEX PHEROMONE
STAPH-CAM373
(Bacillus
cereus) 		5 / 12 ILE A 252
LEU A 294
ILE A 261
PHE A 248
VAL A 312
 None
 1.07A 2ygnA-3n2qA:
undetectable		 2ygnA-3n2qA:
20.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HLW_B_CE3B304_1
(CTX-M-9
EXTENDED-SPECTRUM
BETA-LACTAMASE)		 3n2q SEX PHEROMONE
STAPH-CAM373
(Bacillus
cereus) 		4 / 5 ASN A 124
THR A 195
SER A  73
SER A 153
 None
 1.47A 3hlwB-3n2qA:
undetectable		 3hlwB-3n2qA:
23.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P4W_B_DSFB319_1
(GLR4197 PROTEIN)		 3n2q SEX PHEROMONE
STAPH-CAM373
(Bacillus
cereus) 		5 / 9 TYR A 104
ILE A 174
VAL A 144
ILE A 125
ILE A 146
 None
 1.23A 3p4wB-3n2qA:
undetectable		 3p4wB-3n2qA:
23.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ROD_A_NCAA302_0
(NICOTINAMIDE
N-METHYLTRANSFERASE)		 3n2q SEX PHEROMONE
STAPH-CAM373
(Bacillus
cereus) 		4 / 8 TYR A 130
LEU A  84
ALA A 188
SER A 206
 None
 1.01A 3rodA-3n2qA:
undetectable		 3rodA-3n2qA:
20.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QLF_A_FOLA201_0
(DIHYDROFOLATE
REDUCTASE)		 3n2q SEX PHEROMONE
STAPH-CAM373
(Bacillus
cereus) 		5 / 11 ILE A 189
ALA A 207
LYS A 162
ILE A 125
LEU A 122
 None
 1.06A 4qlfA-3n2qA:
undetectable		 4qlfA-3n2qA:
18.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QLG_A_FOLA201_0
(DIHYDROFOLATE
REDUCTASE)		 3n2q SEX PHEROMONE
STAPH-CAM373
(Bacillus
cereus) 		5 / 12 ILE A 189
ALA A 207
LYS A 162
ILE A 125
LEU A 122
 None
 1.17A 4qlgA-3n2qA:
undetectable		 4qlgA-3n2qA:
18.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I6X_A_8PRA705_1
(SODIUM-DEPENDENT
SEROTONIN
TRANSPORTER)		 3n2q SEX PHEROMONE
STAPH-CAM373
(Bacillus
cereus) 		5 / 10 ALA A 298
ILE A 252
PHE A 248
GLY A 301
VAL A 263
 None
 1.18A 5i6xA-3n2qA:
undetectable		 5i6xA-3n2qA:
17.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NUJ_A_Z80A201_1
(BETA-LACTOGLOBULIN)		 3n2q SEX PHEROMONE
STAPH-CAM373
(Bacillus
cereus) 		4 / 8 VAL A 312
LEU A 306
ILE A 252
VAL A 263
 None
 0.82A 5nujA-3n2qA:
undetectable		 5nujA-3n2qA:
14.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NMP_J_CHDJ101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 3n2q SEX PHEROMONE
STAPH-CAM373
(Bacillus
cereus) 		4 / 7 ILE A 105
LEU A 109
THR A 123
LEU A 122
 None
 0.83A 6nmpA-3n2qA:
undetectable
6nmpJ-3n2qA:
undetectable		 6nmpA-3n2qA:
19.96
6nmpJ-3n2qA:
10.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NMP_W_CHDW101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 3n2q SEX PHEROMONE
STAPH-CAM373
(Bacillus
cereus) 		4 / 5 ILE A 105
LEU A 109
THR A 123
LEU A 122
 None
 0.91A 6nmpN-3n2qA:
undetectable
6nmpW-3n2qA:
undetectable		 6nmpN-3n2qA:
19.96
6nmpW-3n2qA:
10.10