SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3n2s'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YA4_B_CTXB2_1
(CES1 PROTEIN)		 3n2s NADPH-DEPENDENT
NITRO/FLAVIN
REDUCTASE
(Bacillus
subtilis) 		5 / 12 GLY A 136
VAL A 145
LEU A 142
LEU A 161
LEU A 149
 FMN  A 400 ( 3.6A)
None
None
None
None
 1.23A 1ya4B-3n2sA:
undetectable		 1ya4B-3n2sA:
18.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_M_TFPM201_1
(PROTEIN S100-A4)		 3n2s NADPH-DEPENDENT
NITRO/FLAVIN
REDUCTASE
(Bacillus
subtilis) 		4 / 7 GLY A  50
PHE A  79
GLY A 160
PHE A 159
 None
None
None
FMN  A 400 ( 4.8A)
 0.88A 3ko0M-3n2sA:
0.0
3ko0P-3n2sA:
undetectable		 3ko0M-3n2sA:
16.67
3ko0P-3n2sA:
16.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_O_TFPO201_1
(PROTEIN S100-A4)		 3n2s NADPH-DEPENDENT
NITRO/FLAVIN
REDUCTASE
(Bacillus
subtilis) 		4 / 8 GLY A  50
PHE A  79
GLY A 160
PHE A 159
 None
None
None
FMN  A 400 ( 4.8A)
 0.95A 3ko0O-3n2sA:
undetectable
3ko0Q-3n2sA:
undetectable		 3ko0O-3n2sA:
16.67
3ko0Q-3n2sA:
16.67