SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3n2t'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTI_A_CCSA47_0
(GLUTATHIONE
S-TRANSFERASE)		 3n2t PUTATIVE
OXIDOREDUCTASE
(Gluconobacter
oxydans) 		4 / 7 TRP A  23
LEU A 183
GLY A 209
LEU A 281
 None
 0.68A 1gtiA-3n2tA:
undetectable		 1gtiA-3n2tA:
19.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTI_B_CCSB47_0
(GLUTATHIONE
S-TRANSFERASE)		 3n2t PUTATIVE
OXIDOREDUCTASE
(Gluconobacter
oxydans) 		4 / 7 TRP A  23
LEU A 183
GLY A 209
LEU A 281
 None
 0.85A 1gtiB-3n2tA:
undetectable		 1gtiB-3n2tA:
19.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTI_D_CCSD47_0
(GLUTATHIONE
S-TRANSFERASE)		 3n2t PUTATIVE
OXIDOREDUCTASE
(Gluconobacter
oxydans) 		4 / 7 TRP A  23
LEU A 183
GLY A 209
LEU A 281
 None
 0.70A 1gtiD-3n2tA:
undetectable		 1gtiD-3n2tA:
19.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTI_E_CCSE47_0
(GLUTATHIONE
S-TRANSFERASE)		 3n2t PUTATIVE
OXIDOREDUCTASE
(Gluconobacter
oxydans) 		4 / 7 TRP A  23
LEU A 183
GLY A 209
LEU A 281
 None
 0.91A 1gtiE-3n2tA:
undetectable		 1gtiE-3n2tA:
19.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JG4_A_SAMA500_0
(PROTEIN-L-ISOASPARTA
TE
O-METHYLTRANSFERASE)		 3n2t PUTATIVE
OXIDOREDUCTASE
(Gluconobacter
oxydans) 		5 / 12 THR A  22
GLY A 158
THR A  83
ALA A  82
LEU A 126
 None
 1.11A 1jg4A-3n2tA:
undetectable		 1jg4A-3n2tA:
20.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MJL_A_SAMA200_0
(METHIONINE REPRESSOR
PROTEIN METJ)		 3n2t PUTATIVE
OXIDOREDUCTASE
(Gluconobacter
oxydans) 		5 / 11 ALA A 207
ARG A  17
GLU A 199
ALA A 198
LEU A 195
 None
 1.31A 1mjlA-3n2tA:
undetectable
1mjlB-3n2tA:
undetectable		 1mjlA-3n2tA:
17.65
1mjlB-3n2tA:
17.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MX8_A_RTLA135_0
(CELLULAR
RETINOL-BINDING
PROTEIN I, HOLO)		 3n2t PUTATIVE
OXIDOREDUCTASE
(Gluconobacter
oxydans) 		5 / 12 LEU A 273
ALA A 280
LEU A 281
THR A 178
ILE A   6
 None
 1.29A 1mx8A-3n2tA:
undetectable		 1mx8A-3n2tA:
22.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DTT_C_H4BC1002_1
(HYPOTHETICAL PROTEIN
PH0634)		 3n2t PUTATIVE
OXIDOREDUCTASE
(Gluconobacter
oxydans) 		4 / 6 ASP A 114
THR A  83
GLU A  65
GLU A 127
 None
 1.20A 2dttB-3n2tA:
undetectable
2dttC-3n2tA:
undetectable		 2dttB-3n2tA:
18.83
2dttC-3n2tA:
18.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2INE_A_PACA317_0
(ALDOSE REDUCTASE)		 3n2t PUTATIVE
OXIDOREDUCTASE
(Gluconobacter
oxydans) 		4 / 5 VAL A  58
TYR A  59
HIS A 130
TRP A 131
 None
 0.36A 2ineA-3n2tA:
27.3		 2ineA-3n2tA:
24.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ISF_A_PACA317_0
(ALDOSE REDUCTASE)		 3n2t PUTATIVE
OXIDOREDUCTASE
(Gluconobacter
oxydans) 		4 / 5 VAL A  58
TYR A  59
HIS A 130
TRP A 131
 None
 0.27A 2isfA-3n2tA:
27.3		 2isfA-3n2tA:
24.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NYR_B_SVRB401_1
(NAD-DEPENDENT
DEACETYLASE
SIRTUIN-5)		 3n2t PUTATIVE
OXIDOREDUCTASE
(Gluconobacter
oxydans) 		5 / 12 THR A  13
ALA A 156
ALA A 177
ILE A   6
LEU A 281
 None
 1.21A 2nyrA-3n2tA:
undetectable		 2nyrA-3n2tA:
23.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V41_C_BEZC1218_0
(PEROXIREDOXIN 6.)		 3n2t PUTATIVE
OXIDOREDUCTASE
(Gluconobacter
oxydans) 		4 / 8 PRO A 105
THR A 136
PRO A 137
SER A 141
 None
 0.99A 2v41C-3n2tA:
undetectable
2v41D-3n2tA:
undetectable		 2v41C-3n2tA:
21.53
2v41D-3n2tA:
21.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DZY_D_BRLD478_2
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 3n2t PUTATIVE
OXIDOREDUCTASE
(Gluconobacter
oxydans) 		4 / 4 ILE A 190
GLN A 275
ILE A 179
LEU A 185
 None
 1.28A 3dzyD-3n2tA:
undetectable		 3dzyD-3n2tA:
22.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A7A_A_RGZA601_1
(AMINE OXIDASE
[FLAVIN-CONTAINING]
B)		 3n2t PUTATIVE
OXIDOREDUCTASE
(Gluconobacter
oxydans) 		5 / 11 TYR A 208
LEU A 145
GLN A 180
ILE A 129
TYR A  59
 None
 1.28A 4a7aA-3n2tA:
undetectable		 4a7aA-3n2tA:
21.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DC3_A_ADNA401_2
(ADENOSINE KINASE)		 3n2t PUTATIVE
OXIDOREDUCTASE
(Gluconobacter
oxydans) 		4 / 4 LEU A 176
ILE A 138
GLY A 158
PHE A 162
 None
 0.85A 4dc3A-3n2tA:
2.4		 4dc3A-3n2tA:
24.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JQ1_B_NPSB401_1
(ALDO-KETO REDUCTASE
FAMILY 1 MEMBER C2)		 3n2t PUTATIVE
OXIDOREDUCTASE
(Gluconobacter
oxydans) 		4 / 8 VAL A  58
TYR A  59
HIS A 130
VAL A  99
 None
 0.79A 4jq1B-3n2tA:
26.7		 4jq1B-3n2tA:
26.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JQ4_A_IMNA401_1
(ALDO-KETO REDUCTASE
FAMILY 1 MEMBER C2)		 3n2t PUTATIVE
OXIDOREDUCTASE
(Gluconobacter
oxydans) 		5 / 10 VAL A  58
TYR A  59
HIS A 130
VAL A  99
TYR A 208
 None
 0.96A 4jq4A-3n2tA:
26.7		 4jq4A-3n2tA:
26.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JQ4_B_IMNB401_1
(ALDO-KETO REDUCTASE
FAMILY 1 MEMBER C2)		 3n2t PUTATIVE
OXIDOREDUCTASE
(Gluconobacter
oxydans) 		5 / 10 TYR A  59
HIS A 130
VAL A  99
ASN A 161
TYR A 208
 None
 0.73A 4jq4B-3n2tA:
26.7		 4jq4B-3n2tA:
26.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MM8_A_RFXA603_1
(TRANSPORTER)		 3n2t PUTATIVE
OXIDOREDUCTASE
(Gluconobacter
oxydans) 		5 / 12 VAL A  68
ALA A  71
GLY A  27
GLY A  38
THR A  55
 None
 1.06A 4mm8A-3n2tA:
undetectable		 4mm8A-3n2tA:
22.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OKB_A_198A1002_1
(ANDROGEN RECEPTOR)		 3n2t PUTATIVE
OXIDOREDUCTASE
(Gluconobacter
oxydans) 		5 / 12 LEU A 126
GLN A 128
LEU A 281
VAL A 205
ILE A  50
 None
 1.33A 4okbA-3n2tA:
undetectable		 4okbA-3n2tA:
21.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QW0_K_BO2K301_1
(PROTEASOME SUBUNIT
BETA TYPE-5)		 3n2t PUTATIVE
OXIDOREDUCTASE
(Gluconobacter
oxydans) 		4 / 7 ALA A  56
THR A  83
ALA A  82
THR A  22
 None
 0.94A 4qw0K-3n2tA:
undetectable		 4qw0K-3n2tA:
19.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QW0_Y_BO2Y301_1
(PROTEASOME SUBUNIT
BETA TYPE-5)		 3n2t PUTATIVE
OXIDOREDUCTASE
(Gluconobacter
oxydans) 		4 / 7 ALA A  56
THR A  83
ALA A  82
THR A  22
 None
 0.94A 4qw0Y-3n2tA:
undetectable		 4qw0Y-3n2tA:
19.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R38_C_RBFC201_2
(BLUE-LIGHT-ACTIVATED
HISTIDINE KINASE 2)		 3n2t PUTATIVE
OXIDOREDUCTASE
(Gluconobacter
oxydans) 		5 / 9 ILE A  42
LEU A 126
VAL A 121
LEU A 119
ILE A 124
 None
 1.22A 4r38C-3n2tA:
undetectable		 4r38C-3n2tA:
18.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Y8W_C_STRC603_2
(CYTOCHROME P450
21-HYDROXYLASE)		 3n2t PUTATIVE
OXIDOREDUCTASE
(Gluconobacter
oxydans) 		3 / 3 LEU A 116
VAL A  81
ASP A 125
 None
 0.68A 4y8wC-3n2tA:
undetectable		 4y8wC-3n2tA:
20.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QGM_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 3n2t PUTATIVE
OXIDOREDUCTASE
(Gluconobacter
oxydans) 		3 / 3 VAL A 205
VAL A 278
GLN A 275
 None
 0.61A 5qgmA-3n2tA:
undetectable		 5qgmA-3n2tA:
20.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QGW_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 3n2t PUTATIVE
OXIDOREDUCTASE
(Gluconobacter
oxydans) 		3 / 3 VAL A 205
VAL A 278
GLN A 275
 None
 0.69A 5qgwA-3n2tA:
undetectable		 5qgwA-3n2tA:
20.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QGZ_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 3n2t PUTATIVE
OXIDOREDUCTASE
(Gluconobacter
oxydans) 		3 / 3 VAL A 205
VAL A 278
GLN A 275
 None
 0.68A 5qgzA-3n2tA:
undetectable		 5qgzA-3n2tA:
20.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QH0_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 3n2t PUTATIVE
OXIDOREDUCTASE
(Gluconobacter
oxydans) 		3 / 3 VAL A 205
VAL A 278
GLN A 275
 None
 0.68A 5qh0A-3n2tA:
undetectable		 5qh0A-3n2tA:
20.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QH1_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 3n2t PUTATIVE
OXIDOREDUCTASE
(Gluconobacter
oxydans) 		3 / 3 VAL A 205
VAL A 278
GLN A 275
 None
 0.68A 5qh1A-3n2tA:
undetectable		 5qh1A-3n2tA:
20.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QH3_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 3n2t PUTATIVE
OXIDOREDUCTASE
(Gluconobacter
oxydans) 		3 / 3 VAL A 205
VAL A 278
GLN A 275
 None
 0.68A 5qh3A-3n2tA:
undetectable		 5qh3A-3n2tA:
20.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QH4_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 3n2t PUTATIVE
OXIDOREDUCTASE
(Gluconobacter
oxydans) 		3 / 3 VAL A 205
VAL A 278
GLN A 275
 None
 0.68A 5qh4A-3n2tA:
undetectable		 5qh4A-3n2tA:
20.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QH5_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 3n2t PUTATIVE
OXIDOREDUCTASE
(Gluconobacter
oxydans) 		3 / 3 VAL A 205
VAL A 278
GLN A 275
 None
 0.66A 5qh5A-3n2tA:
undetectable		 5qh5A-3n2tA:
20.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QH6_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 3n2t PUTATIVE
OXIDOREDUCTASE
(Gluconobacter
oxydans) 		3 / 3 VAL A 205
VAL A 278
GLN A 275
 None
 0.66A 5qh6A-3n2tA:
undetectable		 5qh6A-3n2tA:
20.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QH7_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 3n2t PUTATIVE
OXIDOREDUCTASE
(Gluconobacter
oxydans) 		3 / 3 VAL A 205
VAL A 278
GLN A 275
 None
 0.68A 5qh7A-3n2tA:
undetectable		 5qh7A-3n2tA:
20.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QHC_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 3n2t PUTATIVE
OXIDOREDUCTASE
(Gluconobacter
oxydans) 		3 / 3 VAL A 205
VAL A 278
GLN A 275
 None
 0.66A 5qhcA-3n2tA:
undetectable		 5qhcA-3n2tA:
20.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5U63_A_ACTA405_0
(THIOREDOXIN
REDUCTASE)		 3n2t PUTATIVE
OXIDOREDUCTASE
(Gluconobacter
oxydans) 		3 / 3 GLY A  86
LEU A  87
HIS A 130
 None
 0.65A 5u63A-3n2tA:
undetectable		 5u63A-3n2tA:
22.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5U63_B_ACTB405_0
(THIOREDOXIN
REDUCTASE)		 3n2t PUTATIVE
OXIDOREDUCTASE
(Gluconobacter
oxydans) 		3 / 3 GLY A  86
LEU A  87
HIS A 130
 None
 0.69A 5u63B-3n2tA:
undetectable		 5u63B-3n2tA:
22.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CDU_G_EY4G502_0
(CHIMERIC ALPHA1GABAA
RECEPTOR)		 3n2t PUTATIVE
OXIDOREDUCTASE
(Gluconobacter
oxydans) 		4 / 8 ILE A   6
VAL A 205
PRO A   9
TYR A 197
 None
 0.96A 6cduG-3n2tA:
undetectable
6cduH-3n2tA:
undetectable		 6cduG-3n2tA:
21.52
6cduH-3n2tA:
21.52