SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3n3k'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1K2R_A_H4BA1760_1
(NITRIC-OXIDE
SYNTHASE)		 3n3k UBIQUITIN
CARBOXYL-TERMINAL
HYDROLASE 8
(Homo
sapiens) 		4 / 7 ARG A 944
TRP A1001
PHE A 946
GLU A 908
 None
 1.48A 1k2rA-3n3kA:
undetectable
1k2rB-3n3kA:
undetectable		 1k2rA-3n3kA:
19.74
1k2rB-3n3kA:
19.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1K2R_B_H4BB2760_1
(NITRIC-OXIDE
SYNTHASE)		 3n3k UBIQUITIN
CARBOXYL-TERMINAL
HYDROLASE 8
(Homo
sapiens) 		4 / 7 TRP A1001
PHE A 946
GLU A 908
ARG A 944
 None
 1.45A 1k2rA-3n3kA:
undetectable
1k2rB-3n3kA:
undetectable		 1k2rA-3n3kA:
19.74
1k2rB-3n3kA:
19.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1K2S_A_H4BA1760_1
(NITRIC-OXIDE
SYNTHASE)		 3n3k UBIQUITIN
CARBOXYL-TERMINAL
HYDROLASE 8
(Homo
sapiens) 		4 / 7 ARG A 944
TRP A1001
PHE A 946
GLU A 908
 None
 1.46A 1k2sA-3n3kA:
undetectable
1k2sB-3n3kA:
undetectable		 1k2sA-3n3kA:
19.74
1k2sB-3n3kA:
19.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1K2S_B_H4BB2760_1
(NITRIC-OXIDE
SYNTHASE)		 3n3k UBIQUITIN
CARBOXYL-TERMINAL
HYDROLASE 8
(Homo
sapiens) 		4 / 6 TRP A1001
PHE A 946
GLU A 908
ARG A 944
 None
 1.40A 1k2sA-3n3kA:
undetectable
1k2sB-3n3kA:
undetectable		 1k2sA-3n3kA:
19.74
1k2sB-3n3kA:
19.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1K2T_A_H4BA1760_1
(NITRIC-OXIDE
SYNTHASE)		 3n3k UBIQUITIN
CARBOXYL-TERMINAL
HYDROLASE 8
(Homo
sapiens) 		4 / 7 ARG A 944
TRP A1001
PHE A 946
GLU A 908
 None
 1.48A 1k2tA-3n3kA:
undetectable
1k2tB-3n3kA:
undetectable		 1k2tA-3n3kA:
19.74
1k2tB-3n3kA:
19.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1K2T_B_H4BB2760_1
(NITRIC-OXIDE
SYNTHASE)		 3n3k UBIQUITIN
CARBOXYL-TERMINAL
HYDROLASE 8
(Homo
sapiens) 		4 / 7 TRP A1001
PHE A 946
GLU A 908
ARG A 944
 None
 1.45A 1k2tA-3n3kA:
undetectable
1k2tB-3n3kA:
undetectable		 1k2tA-3n3kA:
19.74
1k2tB-3n3kA:
19.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1K2U_A_H4BA1760_1
(NITRIC-OXIDE
SYNTHASE)		 3n3k UBIQUITIN
CARBOXYL-TERMINAL
HYDROLASE 8
(Homo
sapiens) 		4 / 7 ARG A 944
TRP A1001
PHE A 946
GLU A 908
 None
 1.47A 1k2uA-3n3kA:
undetectable
1k2uB-3n3kA:
undetectable		 1k2uA-3n3kA:
19.74
1k2uB-3n3kA:
19.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1K2U_B_H4BB2760_1
(NITRIC-OXIDE
SYNTHASE)		 3n3k UBIQUITIN
CARBOXYL-TERMINAL
HYDROLASE 8
(Homo
sapiens) 		4 / 6 TRP A1001
PHE A 946
GLU A 908
ARG A 944
 None
 1.43A 1k2uA-3n3kA:
undetectable
1k2uB-3n3kA:
undetectable		 1k2uA-3n3kA:
19.74
1k2uB-3n3kA:
19.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LZZ_B_H4BB1760_1
(NITRIC-OXIDE
SYNTHASE)		 3n3k UBIQUITIN
CARBOXYL-TERMINAL
HYDROLASE 8
(Homo
sapiens) 		4 / 7 TRP A1001
PHE A 946
GLU A 908
ARG A 944
 None
 1.49A 1lzzA-3n3kA:
undetectable
1lzzB-3n3kA:
undetectable		 1lzzA-3n3kA:
19.74
1lzzB-3n3kA:
19.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1M00_B_H4BB1760_1
(NITRIC-OXIDE
SYNTHASE)		 3n3k UBIQUITIN
CARBOXYL-TERMINAL
HYDROLASE 8
(Homo
sapiens) 		4 / 7 TRP A1001
PHE A 946
GLU A 908
ARG A 944
 None
 1.47A 1m00A-3n3kA:
undetectable
1m00B-3n3kA:
undetectable		 1m00A-3n3kA:
19.74
1m00B-3n3kA:
19.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MMV_B_H4BB2760_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 3n3k UBIQUITIN
CARBOXYL-TERMINAL
HYDROLASE 8
(Homo
sapiens) 		4 / 7 TRP A1001
PHE A 946
GLU A 908
ARG A 944
 None
 1.46A 1mmvA-3n3kA:
undetectable
1mmvB-3n3kA:
undetectable		 1mmvA-3n3kA:
19.74
1mmvB-3n3kA:
19.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NSI_D_H4BD603_1
(PROTEIN (NITRIC
OXIDE SYNTHASE))		 3n3k UBIQUITIN
CARBOXYL-TERMINAL
HYDROLASE 8
(Homo
sapiens) 		4 / 6 TRP A1001
PHE A 946
GLU A 908
ARG A 944
 None
 1.45A 1nsiC-3n3kA:
undetectable
1nsiD-3n3kA:
undetectable		 1nsiC-3n3kA:
21.13
1nsiD-3n3kA:
21.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OM4_B_H4BB761_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 3n3k UBIQUITIN
CARBOXYL-TERMINAL
HYDROLASE 8
(Homo
sapiens) 		4 / 7 TRP A1001
PHE A 946
GLU A 908
ARG A 944
 None
 1.50A 1om4A-3n3kA:
undetectable
1om4B-3n3kA:
undetectable		 1om4A-3n3kA:
19.83
1om4B-3n3kA:
19.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OM5_A_H4BA760_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 3n3k UBIQUITIN
CARBOXYL-TERMINAL
HYDROLASE 8
(Homo
sapiens) 		4 / 8 ARG A 944
TRP A1001
PHE A 946
GLU A 908
 None
 1.48A 1om5A-3n3kA:
undetectable
1om5B-3n3kA:
undetectable		 1om5A-3n3kA:
19.65
1om5B-3n3kA:
19.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OM5_B_H4BB761_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 3n3k UBIQUITIN
CARBOXYL-TERMINAL
HYDROLASE 8
(Homo
sapiens) 		4 / 6 TRP A1001
PHE A 946
GLU A 908
ARG A 944
 None
 1.37A 1om5A-3n3kA:
undetectable
1om5B-3n3kA:
undetectable		 1om5A-3n3kA:
19.65
1om5B-3n3kA:
19.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OSV_B_CHCB201_2
(BILE ACID RECEPTOR)		 3n3k UBIQUITIN
CARBOXYL-TERMINAL
HYDROLASE 8
(Homo
sapiens) 		4 / 5 HIS A1086
ARG A 780
ILE A 791
HIS A1067
 None
 1.23A 1osvB-3n3kA:
0.0		 1osvB-3n3kA:
20.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1P6H_B_H4BB761_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 3n3k UBIQUITIN
CARBOXYL-TERMINAL
HYDROLASE 8
(Homo
sapiens) 		4 / 7 TRP A1001
PHE A 946
GLU A 908
ARG A 944
 None
 1.47A 1p6hA-3n3kA:
undetectable
1p6hB-3n3kA:
undetectable		 1p6hA-3n3kA:
19.65
1p6hB-3n3kA:
19.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1P6I_B_H4BB761_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 3n3k UBIQUITIN
CARBOXYL-TERMINAL
HYDROLASE 8
(Homo
sapiens) 		4 / 7 TRP A1001
PHE A 946
GLU A 908
ARG A 944
 None
 1.49A 1p6iA-3n3kA:
undetectable
1p6iB-3n3kA:
undetectable		 1p6iA-3n3kA:
19.65
1p6iB-3n3kA:
19.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1P6J_B_H4BB761_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 3n3k UBIQUITIN
CARBOXYL-TERMINAL
HYDROLASE 8
(Homo
sapiens) 		4 / 7 TRP A1001
PHE A 946
GLU A 908
ARG A 944
 None
 1.50A 1p6jA-3n3kA:
undetectable
1p6jB-3n3kA:
undetectable		 1p6jA-3n3kA:
19.65
1p6jB-3n3kA:
19.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RS6_A_H4BA760_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 3n3k UBIQUITIN
CARBOXYL-TERMINAL
HYDROLASE 8
(Homo
sapiens) 		4 / 6 ARG A 944
TRP A1001
PHE A 946
GLU A 908
 None
 1.49A 1rs6A-3n3kA:
undetectable
1rs6B-3n3kA:
undetectable		 1rs6A-3n3kA:
19.65
1rs6B-3n3kA:
19.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RS6_B_H4BB761_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 3n3k UBIQUITIN
CARBOXYL-TERMINAL
HYDROLASE 8
(Homo
sapiens) 		4 / 8 TRP A1001
PHE A 946
GLU A 908
ARG A 944
 None
 1.46A 1rs6A-3n3kA:
undetectable
1rs6B-3n3kA:
undetectable		 1rs6A-3n3kA:
19.65
1rs6B-3n3kA:
19.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RS7_A_H4BA760_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 3n3k UBIQUITIN
CARBOXYL-TERMINAL
HYDROLASE 8
(Homo
sapiens) 		4 / 7 ARG A 944
TRP A1001
PHE A 946
GLU A 908
 None
 1.50A 1rs7A-3n3kA:
undetectable
1rs7B-3n3kA:
undetectable		 1rs7A-3n3kA:
19.65
1rs7B-3n3kA:
19.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RS7_B_H4BB761_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 3n3k UBIQUITIN
CARBOXYL-TERMINAL
HYDROLASE 8
(Homo
sapiens) 		4 / 7 TRP A1001
PHE A 946
GLU A 908
ARG A 944
 None
 1.48A 1rs7A-3n3kA:
undetectable
1rs7B-3n3kA:
undetectable		 1rs7A-3n3kA:
19.65
1rs7B-3n3kA:
19.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RS9_B_H4BB761_1
(NITRIC-OXIDE
SYNTHASE,
ENDOTHELIAL)		 3n3k UBIQUITIN
CARBOXYL-TERMINAL
HYDROLASE 8
(Homo
sapiens) 		4 / 6 TRP A1001
PHE A 946
GLU A 908
ARG A 944
 None
 1.49A 1rs9A-3n3kA:
undetectable
1rs9B-3n3kA:
undetectable		 1rs9A-3n3kA:
21.10
1rs9B-3n3kA:
21.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z2B_C_VLBC800_1
(TUBULIN BETA CHAIN
TUBULIN ALPHA CHAIN)		 3n3k UBIQUITIN
(Homo
sapiens) 		4 / 8 LYS B  27
VAL B  26
ASP B  32
LEU B  56
 None
 0.74A 1z2bB-3n3kB:
undetectable		 1z2bB-3n3kB:
13.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZVL_A_H4BA900_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 3n3k UBIQUITIN
CARBOXYL-TERMINAL
HYDROLASE 8
(Homo
sapiens) 		4 / 7 ARG A 944
TRP A1001
PHE A 946
GLU A 908
 None
 1.46A 1zvlA-3n3kA:
undetectable
1zvlB-3n3kA:
undetectable		 1zvlA-3n3kA:
19.48
1zvlB-3n3kA:
19.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZVL_B_H4BB920_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 3n3k UBIQUITIN
CARBOXYL-TERMINAL
HYDROLASE 8
(Homo
sapiens) 		4 / 6 TRP A1001
PHE A 946
GLU A 908
ARG A 944
 None
 1.44A 1zvlA-3n3kA:
undetectable
1zvlB-3n3kA:
undetectable		 1zvlA-3n3kA:
19.48
1zvlB-3n3kA:
19.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZZQ_B_H4BB761_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 3n3k UBIQUITIN
CARBOXYL-TERMINAL
HYDROLASE 8
(Homo
sapiens) 		4 / 7 TRP A1001
PHE A 946
GLU A 908
ARG A 944
 None
 1.49A 1zzqA-3n3kA:
undetectable
1zzqB-3n3kA:
undetectable		 1zzqA-3n3kA:
20.97
1zzqB-3n3kA:
20.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BM9_A_SAMA301_1
(CEPHALOSPORIN
HYDROXYLASE CMCI)		 3n3k UBIQUITIN
CARBOXYL-TERMINAL
HYDROLASE 8
(Homo
sapiens) 		3 / 3 LYS A 835
ASP A 813
ASN A 808
 None
 0.89A 2bm9A-3n3kA:
undetectable		 2bm9A-3n3kA:
19.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2CD2_A_FOLA307_0
(DIHYDROFOLATE
REDUCTASE)		 3n3k UBIQUITIN
(Homo
sapiens) 		5 / 12 ILE B   3
THR B   7
PHE B  45
LEU B  43
ILE B  30
 None
 1.02A 2cd2A-3n3kB:
undetectable		 2cd2A-3n3kB:
19.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EJG_A_ADNA1501_1
(235AA LONG
HYPOTHETICAL
BIOTIN--[ACETYL-COA-
CARBOXYLASE] LIGASE)		 3n3k UBIQUITIN
CARBOXYL-TERMINAL
HYDROLASE 8
(Homo
sapiens) 		4 / 7 ARG A 807
ASN A1074
PRO A 774
ALA A 775
 None
 1.01A 2ejgA-3n3kA:
undetectable		 2ejgA-3n3kA:
20.35
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2FCN_A_DVAA35_0
(UBIQUITIN)		 3n3k UBIQUITIN
(Homo
sapiens) 		4 / 4 GLN B  31
GLU B  34
ILE B  36
PRO B  37
 None
 1.02A 2fcnA-3n3kB:
16.2		 2fcnA-3n3kB:
78.48
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2FCN_B_DVAB35_0
(UBIQUITIN)		 3n3k UBIQUITIN
(Homo
sapiens) 		4 / 6 GLN B  31
GLU B  34
ILE B  36
PRO B  37
 None
 0.59A 2fcnA-3n3kB:
16.2
2fcnB-3n3kB:
16.0		 2fcnA-3n3kB:
78.48
2fcnB-3n3kB:
78.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2G6H_B_H4BB761_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 3n3k UBIQUITIN
CARBOXYL-TERMINAL
HYDROLASE 8
(Homo
sapiens) 		4 / 6 TRP A1001
PHE A 946
GLU A 908
ARG A 944
 None
 1.46A 2g6hA-3n3kA:
undetectable
2g6hB-3n3kA:
undetectable		 2g6hA-3n3kA:
19.91
2g6hB-3n3kA:
19.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2G6K_B_H4BB761_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 3n3k UBIQUITIN
CARBOXYL-TERMINAL
HYDROLASE 8
(Homo
sapiens) 		4 / 7 TRP A1001
PHE A 946
GLU A 908
ARG A 944
 None
 1.46A 2g6kA-3n3kA:
undetectable
2g6kB-3n3kA:
undetectable		 2g6kA-3n3kA:
19.91
2g6kB-3n3kA:
19.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HX3_B_H4BB760_1
(NITRIC-OXIDE
SYNTHASE)		 3n3k UBIQUITIN
CARBOXYL-TERMINAL
HYDROLASE 8
(Homo
sapiens) 		4 / 6 TRP A1001
PHE A 946
GLU A 908
ARG A 944
 None
 1.46A 2hx3A-3n3kA:
undetectable
2hx3B-3n3kA:
undetectable		 2hx3A-3n3kA:
19.83
2hx3B-3n3kA:
19.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HX4_B_H4BB760_1
(NITRIC-OXIDE
SYNTHASE)		 3n3k UBIQUITIN
CARBOXYL-TERMINAL
HYDROLASE 8
(Homo
sapiens) 		4 / 7 TRP A1001
PHE A 946
GLU A 908
ARG A 944
 None
 1.43A 2hx4A-3n3kA:
undetectable
2hx4B-3n3kA:
undetectable		 2hx4A-3n3kA:
19.83
2hx4B-3n3kA:
19.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YGN_A_PCFA1179_1
(WNT INHIBITORY
FACTOR 1)		 3n3k UBIQUITIN
CARBOXYL-TERMINAL
HYDROLASE 8
(Homo
sapiens) 		4 / 5 ILE A 921
PHE A 830
VAL A1088
PHE A1105
 None
 1.00A 2ygnA-3n3kA:
undetectable		 2ygnA-3n3kA:
15.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YS6_A_GLYA431_0
(PHOSPHORIBOSYLGLYCIN
AMIDE SYNTHETASE)		 3n3k UBIQUITIN
CARBOXYL-TERMINAL
HYDROLASE 8
(Homo
sapiens) 		4 / 8 LYS A 891
ASN A 815
GLY A 821
GLU A 882
 None
 0.98A 2ys6A-3n3kA:
undetectable		 2ys6A-3n3kA:
23.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B3N_B_H4BB760_1
(NITRIC-OXIDE
SYNTHASE)		 3n3k UBIQUITIN
CARBOXYL-TERMINAL
HYDROLASE 8
(Homo
sapiens) 		4 / 7 TRP A1001
PHE A 946
GLU A 908
ARG A 944
 None
 1.46A 3b3nA-3n3kA:
undetectable
3b3nB-3n3kA:
undetectable		 3b3nA-3n3kA:
19.83
3b3nB-3n3kA:
19.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B3O_B_H4BB760_1
(NITRIC-OXIDE
SYNTHASE)		 3n3k UBIQUITIN
CARBOXYL-TERMINAL
HYDROLASE 8
(Homo
sapiens) 		4 / 7 TRP A1001
PHE A 946
GLU A 908
ARG A 944
 None
 1.46A 3b3oA-3n3kA:
undetectable
3b3oB-3n3kA:
undetectable		 3b3oA-3n3kA:
19.83
3b3oB-3n3kA:
19.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B3P_A_H4BA760_1
(NITRIC-OXIDE
SYNTHASE)		 3n3k UBIQUITIN
CARBOXYL-TERMINAL
HYDROLASE 8
(Homo
sapiens) 		4 / 7 ARG A 944
TRP A1001
PHE A 946
GLU A 908
 None
 1.45A 3b3pA-3n3kA:
undetectable
3b3pB-3n3kA:
undetectable		 3b3pA-3n3kA:
19.83
3b3pB-3n3kA:
19.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B3P_B_H4BB760_1
(NITRIC-OXIDE
SYNTHASE)		 3n3k UBIQUITIN
CARBOXYL-TERMINAL
HYDROLASE 8
(Homo
sapiens) 		4 / 8 TRP A1001
PHE A 946
GLU A 908
ARG A 944
 None
 1.36A 3b3pA-3n3kA:
undetectable
3b3pB-3n3kA:
undetectable		 3b3pA-3n3kA:
19.83
3b3pB-3n3kA:
19.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FC5_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3n3k UBIQUITIN
CARBOXYL-TERMINAL
HYDROLASE 8
(Homo
sapiens) 		4 / 7 ARG A 944
TRP A1001
PHE A 946
GLU A 908
 None
 1.48A 3fc5A-3n3kA:
undetectable
3fc5B-3n3kA:
undetectable		 3fc5A-3n3kA:
19.83
3fc5B-3n3kA:
19.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FC5_B_H4BB761_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3n3k UBIQUITIN
CARBOXYL-TERMINAL
HYDROLASE 8
(Homo
sapiens) 		4 / 7 TRP A1001
PHE A 946
GLU A 908
ARG A 944
 None
 1.48A 3fc5A-3n3kA:
undetectable
3fc5B-3n3kA:
undetectable		 3fc5A-3n3kA:
19.83
3fc5B-3n3kA:
19.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HSP_B_H4BB1760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3n3k UBIQUITIN
CARBOXYL-TERMINAL
HYDROLASE 8
(Homo
sapiens) 		4 / 7 TRP A1001
PHE A 946
GLU A 908
ARG A 944
 None
 1.49A 3hspA-3n3kA:
undetectable
3hspB-3n3kA:
undetectable		 3hspA-3n3kA:
19.83
3hspB-3n3kA:
19.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JT3_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3n3k UBIQUITIN
CARBOXYL-TERMINAL
HYDROLASE 8
(Homo
sapiens) 		4 / 7 TRP A1001
PHE A 946
GLU A 908
ARG A 944
 None
 1.47A 3jt3A-3n3kA:
undetectable
3jt3B-3n3kA:
undetectable		 3jt3A-3n3kA:
19.83
3jt3B-3n3kA:
19.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JT5_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3n3k UBIQUITIN
CARBOXYL-TERMINAL
HYDROLASE 8
(Homo
sapiens) 		4 / 7 TRP A1001
PHE A 946
GLU A 908
ARG A 944
 None
 1.48A 3jt5A-3n3kA:
undetectable
3jt5B-3n3kA:
undetectable		 3jt5A-3n3kA:
19.83
3jt5B-3n3kA:
19.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JT6_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3n3k UBIQUITIN
CARBOXYL-TERMINAL
HYDROLASE 8
(Homo
sapiens) 		4 / 7 TRP A1001
PHE A 946
GLU A 908
ARG A 944
 None
 1.44A 3jt6A-3n3kA:
undetectable
3jt6B-3n3kA:
undetectable		 3jt6A-3n3kA:
19.83
3jt6B-3n3kA:
19.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JT7_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3n3k UBIQUITIN
CARBOXYL-TERMINAL
HYDROLASE 8
(Homo
sapiens) 		4 / 7 TRP A1001
PHE A 946
GLU A 908
ARG A 944
 None
 1.50A 3jt7A-3n3kA:
undetectable
3jt7B-3n3kA:
undetectable		 3jt7A-3n3kA:
19.83
3jt7B-3n3kA:
19.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JT9_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3n3k UBIQUITIN
CARBOXYL-TERMINAL
HYDROLASE 8
(Homo
sapiens) 		4 / 7 TRP A1001
PHE A 946
GLU A 908
ARG A 944
 None
 1.50A 3jt9A-3n3kA:
undetectable
3jt9B-3n3kA:
undetectable		 3jt9A-3n3kA:
19.83
3jt9B-3n3kA:
19.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JWS_B_H4BB761_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3n3k UBIQUITIN
CARBOXYL-TERMINAL
HYDROLASE 8
(Homo
sapiens) 		4 / 7 TRP A1001
PHE A 946
GLU A 908
ARG A 944
 None
 1.48A 3jwsA-3n3kA:
undetectable
3jwsB-3n3kA:
undetectable		 3jwsA-3n3kA:
20.64
3jwsB-3n3kA:
20.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JWT_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3n3k UBIQUITIN
CARBOXYL-TERMINAL
HYDROLASE 8
(Homo
sapiens) 		4 / 7 ARG A 944
TRP A1001
PHE A 946
GLU A 908
 None
 1.49A 3jwtA-3n3kA:
undetectable
3jwtB-3n3kA:
undetectable		 3jwtA-3n3kA:
20.64
3jwtB-3n3kA:
20.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JWT_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3n3k UBIQUITIN
CARBOXYL-TERMINAL
HYDROLASE 8
(Homo
sapiens) 		4 / 7 TRP A1001
PHE A 946
GLU A 908
ARG A 944
 None
 1.48A 3jwtA-3n3kA:
undetectable
3jwtB-3n3kA:
undetectable		 3jwtA-3n3kA:
20.64
3jwtB-3n3kA:
20.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JWU_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3n3k UBIQUITIN
CARBOXYL-TERMINAL
HYDROLASE 8
(Homo
sapiens) 		4 / 7 TRP A1001
PHE A 946
GLU A 908
ARG A 944
 None
 1.46A 3jwuA-3n3kA:
undetectable
3jwuB-3n3kA:
undetectable		 3jwuA-3n3kA:
20.64
3jwuB-3n3kA:
20.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JWV_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3n3k UBIQUITIN
CARBOXYL-TERMINAL
HYDROLASE 8
(Homo
sapiens) 		4 / 7 TRP A1001
PHE A 946
GLU A 908
ARG A 944
 None
 1.46A 3jwvA-3n3kA:
undetectable
3jwvB-3n3kA:
undetectable		 3jwvA-3n3kA:
20.64
3jwvB-3n3kA:
20.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JX0_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3n3k UBIQUITIN
CARBOXYL-TERMINAL
HYDROLASE 8
(Homo
sapiens) 		4 / 7 ARG A 944
TRP A1001
PHE A 946
GLU A 908
 None
 1.50A 3jx0A-3n3kA:
undetectable
3jx0B-3n3kA:
undetectable		 3jx0A-3n3kA:
20.89
3jx0B-3n3kA:
20.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JX0_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3n3k UBIQUITIN
CARBOXYL-TERMINAL
HYDROLASE 8
(Homo
sapiens) 		4 / 7 TRP A1001
PHE A 946
GLU A 908
ARG A 944
 None
 1.43A 3jx0A-3n3kA:
undetectable
3jx0B-3n3kA:
undetectable		 3jx0A-3n3kA:
20.89
3jx0B-3n3kA:
20.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LK0_D_Z80D92_1
(PROTEIN S100-B)		 3n3k UBIQUITIN
CARBOXYL-TERMINAL
HYDROLASE 8
(Homo
sapiens) 		3 / 3 HIS A 881
PHE A 830
PHE A 805
 None
 0.64A 3lk0D-3n3kA:
0.1		 3lk0D-3n3kA:
12.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N2R_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE)		 3n3k UBIQUITIN
CARBOXYL-TERMINAL
HYDROLASE 8
(Homo
sapiens) 		4 / 7 TRP A1001
PHE A 946
GLU A 908
ARG A 944
 None
 1.49A 3n2rA-3n3kA:
undetectable
3n2rB-3n3kA:
undetectable		 3n2rA-3n3kA:
19.83
3n2rB-3n3kA:
19.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N5Z_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE)		 3n3k UBIQUITIN
CARBOXYL-TERMINAL
HYDROLASE 8
(Homo
sapiens) 		4 / 7 TRP A1001
PHE A 946
GLU A 908
ARG A 944
 None
 1.49A 3n5zA-3n3kA:
undetectable
3n5zB-3n3kA:
undetectable		 3n5zA-3n3kA:
19.83
3n5zB-3n3kA:
19.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N67_A_H4BA600_1
(NITRIC OXIDE
SYNTHASE)		 3n3k UBIQUITIN
CARBOXYL-TERMINAL
HYDROLASE 8
(Homo
sapiens) 		4 / 6 ARG A 944
TRP A1001
PHE A 946
GLU A 908
 None
 1.49A 3n67A-3n3kA:
0.0
3n67B-3n3kA:
0.0		 3n67A-3n3kA:
20.33
3n67B-3n3kA:
20.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N69_A_H4BA600_1
(NITRIC OXIDE
SYNTHASE)		 3n3k UBIQUITIN
CARBOXYL-TERMINAL
HYDROLASE 8
(Homo
sapiens) 		4 / 6 ARG A 944
TRP A1001
PHE A 946
GLU A 908
 None
 1.50A 3n69A-3n3kA:
0.0
3n69B-3n3kA:
0.0		 3n69A-3n3kA:
20.33
3n69B-3n3kA:
20.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLK_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3n3k UBIQUITIN
CARBOXYL-TERMINAL
HYDROLASE 8
(Homo
sapiens) 		4 / 7 TRP A1001
PHE A 946
GLU A 908
ARG A 944
 None
 1.46A 3nlkA-3n3kA:
undetectable
3nlkB-3n3kA:
undetectable		 3nlkA-3n3kA:
20.64
3nlkB-3n3kA:
20.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLM_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3n3k UBIQUITIN
CARBOXYL-TERMINAL
HYDROLASE 8
(Homo
sapiens) 		4 / 7 ARG A 944
TRP A1001
PHE A 946
GLU A 908
 None
 1.50A 3nlmA-3n3kA:
undetectable
3nlmB-3n3kA:
undetectable		 3nlmA-3n3kA:
19.83
3nlmB-3n3kA:
19.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLM_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3n3k UBIQUITIN
CARBOXYL-TERMINAL
HYDROLASE 8
(Homo
sapiens) 		4 / 7 TRP A1001
PHE A 946
GLU A 908
ARG A 944
 None
 1.48A 3nlmA-3n3kA:
undetectable
3nlmB-3n3kA:
undetectable		 3nlmA-3n3kA:
19.83
3nlmB-3n3kA:
19.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLN_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3n3k UBIQUITIN
CARBOXYL-TERMINAL
HYDROLASE 8
(Homo
sapiens) 		4 / 7 ARG A 944
TRP A1001
PHE A 946
GLU A 908
 None
 1.48A 3nlnA-3n3kA:
undetectable
3nlnB-3n3kA:
undetectable		 3nlnA-3n3kA:
20.64
3nlnB-3n3kA:
20.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLN_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3n3k UBIQUITIN
CARBOXYL-TERMINAL
HYDROLASE 8
(Homo
sapiens) 		4 / 7 TRP A1001
PHE A 946
GLU A 908
ARG A 944
 None
 1.44A 3nlnA-3n3kA:
undetectable
3nlnB-3n3kA:
undetectable		 3nlnA-3n3kA:
20.64
3nlnB-3n3kA:
20.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLO_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3n3k UBIQUITIN
CARBOXYL-TERMINAL
HYDROLASE 8
(Homo
sapiens) 		4 / 7 ARG A 944
TRP A1001
PHE A 946
GLU A 908
 None
 1.44A 3nloA-3n3kA:
undetectable
3nloB-3n3kA:
undetectable		 3nloA-3n3kA:
20.64
3nloB-3n3kA:
20.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLO_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3n3k UBIQUITIN
CARBOXYL-TERMINAL
HYDROLASE 8
(Homo
sapiens) 		4 / 7 TRP A1001
PHE A 946
GLU A 908
ARG A 944
 None
 1.45A 3nloA-3n3kA:
undetectable
3nloB-3n3kA:
undetectable		 3nloA-3n3kA:
20.64
3nloB-3n3kA:
20.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLV_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3n3k UBIQUITIN
CARBOXYL-TERMINAL
HYDROLASE 8
(Homo
sapiens) 		4 / 7 TRP A1001
PHE A 946
GLU A 908
ARG A 944
 None
 1.44A 3nlvA-3n3kA:
undetectable
3nlvB-3n3kA:
undetectable		 3nlvA-3n3kA:
19.83
3nlvB-3n3kA:
19.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLW_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3n3k UBIQUITIN
CARBOXYL-TERMINAL
HYDROLASE 8
(Homo
sapiens) 		4 / 7 TRP A1001
PHE A 946
GLU A 908
ARG A 944
 None
 1.45A 3nlwA-3n3kA:
undetectable
3nlwB-3n3kA:
undetectable		 3nlwA-3n3kA:
19.83
3nlwB-3n3kA:
19.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLZ_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3n3k UBIQUITIN
CARBOXYL-TERMINAL
HYDROLASE 8
(Homo
sapiens) 		4 / 7 TRP A1001
PHE A 946
GLU A 908
ARG A 944
 None
 1.49A 3nlzA-3n3kA:
undetectable
3nlzB-3n3kA:
undetectable		 3nlzA-3n3kA:
19.83
3nlzB-3n3kA:
19.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NM0_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3n3k UBIQUITIN
CARBOXYL-TERMINAL
HYDROLASE 8
(Homo
sapiens) 		4 / 7 ARG A 944
TRP A1001
PHE A 946
GLU A 908
 None
 1.50A 3nm0A-3n3kA:
undetectable
3nm0B-3n3kA:
undetectable		 3nm0A-3n3kA:
19.83
3nm0B-3n3kA:
19.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NM0_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3n3k UBIQUITIN
CARBOXYL-TERMINAL
HYDROLASE 8
(Homo
sapiens) 		4 / 7 TRP A1001
PHE A 946
GLU A 908
ARG A 944
 None
 1.50A 3nm0A-3n3kA:
undetectable
3nm0B-3n3kA:
undetectable		 3nm0A-3n3kA:
19.83
3nm0B-3n3kA:
19.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NNY_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3n3k UBIQUITIN
CARBOXYL-TERMINAL
HYDROLASE 8
(Homo
sapiens) 		4 / 7 TRP A1001
PHE A 946
GLU A 908
ARG A 944
 None
 1.48A 3nnyA-3n3kA:
undetectable
3nnyB-3n3kA:
undetectable		 3nnyA-3n3kA:
19.83
3nnyB-3n3kA:
19.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NNZ_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3n3k UBIQUITIN
CARBOXYL-TERMINAL
HYDROLASE 8
(Homo
sapiens) 		4 / 7 TRP A1001
PHE A 946
GLU A 908
ARG A 944
 None
 1.48A 3nnzA-3n3kA:
undetectable
3nnzB-3n3kA:
undetectable		 3nnzA-3n3kA:
19.83
3nnzB-3n3kA:
19.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PNE_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3n3k UBIQUITIN
CARBOXYL-TERMINAL
HYDROLASE 8
(Homo
sapiens) 		4 / 7 TRP A1001
PHE A 946
GLU A 908
ARG A 944
 None
 1.48A 3pneA-3n3kA:
undetectable
3pneB-3n3kA:
undetectable		 3pneA-3n3kA:
19.83
3pneB-3n3kA:
19.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PNG_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3n3k UBIQUITIN
CARBOXYL-TERMINAL
HYDROLASE 8
(Homo
sapiens) 		4 / 7 TRP A1001
PHE A 946
GLU A 908
ARG A 944
 None
 1.48A 3pngA-3n3kA:
undetectable
3pngB-3n3kA:
undetectable		 3pngA-3n3kA:
19.83
3pngB-3n3kA:
19.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3Q99_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3n3k UBIQUITIN
CARBOXYL-TERMINAL
HYDROLASE 8
(Homo
sapiens) 		4 / 7 TRP A1001
PHE A 946
GLU A 908
ARG A 944
 None
 1.50A 3q99A-3n3kA:
undetectable
3q99B-3n3kA:
undetectable		 3q99A-3n3kA:
19.83
3q99B-3n3kA:
19.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3Q9A_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3n3k UBIQUITIN
CARBOXYL-TERMINAL
HYDROLASE 8
(Homo
sapiens) 		4 / 7 TRP A1001
PHE A 946
GLU A 908
ARG A 944
 None
 1.49A 3q9aA-3n3kA:
undetectable
3q9aB-3n3kA:
undetectable		 3q9aA-3n3kA:
19.83
3q9aB-3n3kA:
19.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RQJ_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3n3k UBIQUITIN
CARBOXYL-TERMINAL
HYDROLASE 8
(Homo
sapiens) 		4 / 6 ARG A 944
TRP A1001
PHE A 946
GLU A 908
 None
 1.50A 3rqjA-3n3kA:
undetectable
3rqjB-3n3kA:
undetectable		 3rqjA-3n3kA:
19.83
3rqjB-3n3kA:
19.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RQJ_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3n3k UBIQUITIN
CARBOXYL-TERMINAL
HYDROLASE 8
(Homo
sapiens) 		4 / 7 TRP A1001
PHE A 946
GLU A 908
ARG A 944
 None
 1.46A 3rqjA-3n3kA:
undetectable
3rqjB-3n3kA:
undetectable		 3rqjA-3n3kA:
19.83
3rqjB-3n3kA:
19.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RQK_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3n3k UBIQUITIN
CARBOXYL-TERMINAL
HYDROLASE 8
(Homo
sapiens) 		4 / 7 TRP A1001
PHE A 946
GLU A 908
ARG A 944
 None
 1.47A 3rqkA-3n3kA:
undetectable
3rqkB-3n3kA:
undetectable		 3rqkA-3n3kA:
19.83
3rqkB-3n3kA:
19.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RQL_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3n3k UBIQUITIN
CARBOXYL-TERMINAL
HYDROLASE 8
(Homo
sapiens) 		4 / 7 ARG A 944
TRP A1001
PHE A 946
GLU A 908
 None
 1.49A 3rqlA-3n3kA:
undetectable
3rqlB-3n3kA:
undetectable		 3rqlA-3n3kA:
19.83
3rqlB-3n3kA:
19.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RQM_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3n3k UBIQUITIN
CARBOXYL-TERMINAL
HYDROLASE 8
(Homo
sapiens) 		4 / 7 TRP A1001
PHE A 946
GLU A 908
ARG A 944
 None
 1.50A 3rqmA-3n3kA:
undetectable
3rqmB-3n3kA:
undetectable		 3rqmA-3n3kA:
19.83
3rqmB-3n3kA:
19.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RQN_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3n3k UBIQUITIN
CARBOXYL-TERMINAL
HYDROLASE 8
(Homo
sapiens) 		4 / 7 TRP A1001
PHE A 946
GLU A 908
ARG A 944
 None
 1.49A 3rqnA-3n3kA:
undetectable
3rqnB-3n3kA:
undetectable		 3rqnA-3n3kA:
19.83
3rqnB-3n3kA:
19.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SVP_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3n3k UBIQUITIN
CARBOXYL-TERMINAL
HYDROLASE 8
(Homo
sapiens) 		4 / 6 TRP A1001
PHE A 946
GLU A 908
ARG A 944
 None
 1.45A 3svpA-3n3kA:
undetectable
3svpB-3n3kA:
undetectable		 3svpA-3n3kA:
19.83
3svpB-3n3kA:
19.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3T3S_B_9PLB1_1
(CYTOCHROME P450 2A13)		 3n3k UBIQUITIN
CARBOXYL-TERMINAL
HYDROLASE 8
(Homo
sapiens) 		4 / 6 PHE A1081
PHE A1083
ASN A 797
ALA A1075
 None
 1.15A 3t3sB-3n3kA:
undetectable		 3t3sB-3n3kA:
22.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TYL_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3n3k UBIQUITIN
CARBOXYL-TERMINAL
HYDROLASE 8
(Homo
sapiens) 		4 / 7 ARG A 944
TRP A1001
PHE A 946
GLU A 908
 None
 1.49A 3tylA-3n3kA:
undetectable
3tylB-3n3kA:
undetectable		 3tylA-3n3kA:
19.83
3tylB-3n3kA:
19.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TYL_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3n3k UBIQUITIN
CARBOXYL-TERMINAL
HYDROLASE 8
(Homo
sapiens) 		4 / 7 TRP A1001
PHE A 946
GLU A 908
ARG A 944
 None
 1.47A 3tylA-3n3kA:
undetectable
3tylB-3n3kA:
undetectable		 3tylA-3n3kA:
19.83
3tylB-3n3kA:
19.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TYM_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3n3k UBIQUITIN
CARBOXYL-TERMINAL
HYDROLASE 8
(Homo
sapiens) 		4 / 7 ARG A 944
TRP A1001
PHE A 946
GLU A 908
 None
 1.48A 3tymA-3n3kA:
undetectable
3tymB-3n3kA:
undetectable		 3tymA-3n3kA:
19.83
3tymB-3n3kA:
19.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TYM_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3n3k UBIQUITIN
CARBOXYL-TERMINAL
HYDROLASE 8
(Homo
sapiens) 		4 / 7 TRP A1001
PHE A 946
GLU A 908
ARG A 944
 None
 1.44A 3tymA-3n3kA:
undetectable
3tymB-3n3kA:
undetectable		 3tymA-3n3kA:
19.83
3tymB-3n3kA:
19.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TYN_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3n3k UBIQUITIN
CARBOXYL-TERMINAL
HYDROLASE 8
(Homo
sapiens) 		4 / 7 TRP A1001
PHE A 946
GLU A 908
ARG A 944
 None
 1.45A 3tynA-3n3kA:
undetectable
3tynB-3n3kA:
undetectable		 3tynA-3n3kA:
19.83
3tynB-3n3kA:
19.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TYO_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3n3k UBIQUITIN
CARBOXYL-TERMINAL
HYDROLASE 8
(Homo
sapiens) 		4 / 7 ARG A 944
TRP A1001
PHE A 946
GLU A 908
 None
 1.49A 3tyoA-3n3kA:
undetectable
3tyoB-3n3kA:
undetectable		 3tyoA-3n3kA:
19.83
3tyoB-3n3kA:
19.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TYO_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3n3k UBIQUITIN
CARBOXYL-TERMINAL
HYDROLASE 8
(Homo
sapiens) 		4 / 7 TRP A1001
PHE A 946
GLU A 908
ARG A 944
 None
 1.46A 3tyoA-3n3kA:
undetectable
3tyoB-3n3kA:
undetectable		 3tyoA-3n3kA:
19.83
3tyoB-3n3kA:
19.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UFO_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3n3k UBIQUITIN
CARBOXYL-TERMINAL
HYDROLASE 8
(Homo
sapiens) 		4 / 7 TRP A1001
PHE A 946
GLU A 908
ARG A 944
 None
 1.47A 3ufoA-3n3kA:
undetectable
3ufoB-3n3kA:
undetectable		 3ufoA-3n3kA:
19.83
3ufoB-3n3kA:
19.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UFP_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3n3k UBIQUITIN
CARBOXYL-TERMINAL
HYDROLASE 8
(Homo
sapiens) 		4 / 7 ARG A 944
TRP A1001
PHE A 946
GLU A 908
 None
 1.43A 3ufpA-3n3kA:
undetectable
3ufpB-3n3kA:
undetectable		 3ufpA-3n3kA:
19.83
3ufpB-3n3kA:
19.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UFP_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3n3k UBIQUITIN
CARBOXYL-TERMINAL
HYDROLASE 8
(Homo
sapiens) 		4 / 7 TRP A1001
PHE A 946
GLU A 908
ARG A 944
 None
 1.41A 3ufpA-3n3kA:
undetectable
3ufpB-3n3kA:
undetectable		 3ufpA-3n3kA:
19.83
3ufpB-3n3kA:
19.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UFQ_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3n3k UBIQUITIN
CARBOXYL-TERMINAL
HYDROLASE 8
(Homo
sapiens) 		4 / 6 ARG A 944
TRP A1001
PHE A 946
GLU A 908
 None
 1.47A 3ufqA-3n3kA:
undetectable
3ufqB-3n3kA:
undetectable		 3ufqA-3n3kA:
19.83
3ufqB-3n3kA:
19.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UFQ_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3n3k UBIQUITIN
CARBOXYL-TERMINAL
HYDROLASE 8
(Homo
sapiens) 		4 / 7 TRP A1001
PHE A 946
GLU A 908
ARG A 944
 None
 1.47A 3ufqA-3n3kA:
undetectable
3ufqB-3n3kA:
undetectable		 3ufqA-3n3kA:
19.83
3ufqB-3n3kA:
19.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UFR_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3n3k UBIQUITIN
CARBOXYL-TERMINAL
HYDROLASE 8
(Homo
sapiens) 		4 / 6 ARG A 944
TRP A1001
PHE A 946
GLU A 908
 None
 1.42A 3ufrA-3n3kA:
undetectable
3ufrB-3n3kA:
undetectable		 3ufrA-3n3kA:
19.83
3ufrB-3n3kA:
19.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UFS_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3n3k UBIQUITIN
CARBOXYL-TERMINAL
HYDROLASE 8
(Homo
sapiens) 		4 / 7 TRP A1001
PHE A 946
GLU A 908
ARG A 944
 None
 1.44A 3ufsA-3n3kA:
undetectable
3ufsB-3n3kA:
undetectable		 3ufsA-3n3kA:
19.83
3ufsB-3n3kA:
19.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UFT_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3n3k UBIQUITIN
CARBOXYL-TERMINAL
HYDROLASE 8
(Homo
sapiens) 		4 / 7 ARG A 944
TRP A1001
PHE A 946
GLU A 908
 None
 1.49A 3uftA-3n3kA:
undetectable
3uftB-3n3kA:
undetectable		 3uftA-3n3kA:
19.83
3uftB-3n3kA:
19.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UFT_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3n3k UBIQUITIN
CARBOXYL-TERMINAL
HYDROLASE 8
(Homo
sapiens) 		4 / 7 TRP A1001
PHE A 946
GLU A 908
ARG A 944
 None
 1.48A 3uftA-3n3kA:
undetectable
3uftB-3n3kA:
undetectable		 3uftA-3n3kA:
19.83
3uftB-3n3kA:
19.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UFU_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3n3k UBIQUITIN
CARBOXYL-TERMINAL
HYDROLASE 8
(Homo
sapiens) 		4 / 7 ARG A 944
TRP A1001
PHE A 946
GLU A 908
 None
 1.49A 3ufuA-3n3kA:
undetectable
3ufuB-3n3kA:
undetectable		 3ufuA-3n3kA:
19.83
3ufuB-3n3kA:
19.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UFU_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3n3k UBIQUITIN
CARBOXYL-TERMINAL
HYDROLASE 8
(Homo
sapiens) 		4 / 7 TRP A1001
PHE A 946
GLU A 908
ARG A 944
 None
 1.49A 3ufuA-3n3kA:
undetectable
3ufuB-3n3kA:
undetectable		 3ufuA-3n3kA:
19.83
3ufuB-3n3kA:
19.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UFW_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3n3k UBIQUITIN
CARBOXYL-TERMINAL
HYDROLASE 8
(Homo
sapiens) 		4 / 6 ARG A 944
TRP A1001
PHE A 946
GLU A 908
 None
 1.50A 3ufwA-3n3kA:
undetectable
3ufwB-3n3kA:
undetectable		 3ufwA-3n3kA:
19.83
3ufwB-3n3kA:
19.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UFW_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3n3k UBIQUITIN
CARBOXYL-TERMINAL
HYDROLASE 8
(Homo
sapiens) 		4 / 6 TRP A1001
PHE A 946
GLU A 908
ARG A 944
 None
 1.46A 3ufwA-3n3kA:
undetectable
3ufwB-3n3kA:
undetectable		 3ufwA-3n3kA:
19.83
3ufwB-3n3kA:
19.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C39_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3n3k UBIQUITIN
CARBOXYL-TERMINAL
HYDROLASE 8
(Homo
sapiens) 		4 / 7 ARG A 944
TRP A1001
PHE A 946
GLU A 908
 None
 1.50A 4c39A-3n3kA:
undetectable
4c39B-3n3kA:
undetectable		 4c39A-3n3kA:
19.83
4c39B-3n3kA:
19.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C39_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3n3k UBIQUITIN
CARBOXYL-TERMINAL
HYDROLASE 8
(Homo
sapiens) 		4 / 7 TRP A1001
PHE A 946
GLU A 908
ARG A 944
 None
 1.46A 4c39A-3n3kA:
undetectable
4c39B-3n3kA:
undetectable		 4c39A-3n3kA:
19.83
4c39B-3n3kA:
19.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CAM_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3n3k UBIQUITIN
CARBOXYL-TERMINAL
HYDROLASE 8
(Homo
sapiens) 		4 / 7 TRP A1001
PHE A 946
GLU A 908
ARG A 944
 None
 1.50A 4camA-3n3kA:
undetectable
4camB-3n3kA:
undetectable		 4camA-3n3kA:
19.83
4camB-3n3kA:
19.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CAN_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3n3k UBIQUITIN
CARBOXYL-TERMINAL
HYDROLASE 8
(Homo
sapiens) 		4 / 7 ARG A 944
TRP A1001
PHE A 946
GLU A 908
 None
 1.50A 4canA-3n3kA:
undetectable
4canB-3n3kA:
undetectable		 4canA-3n3kA:
19.83
4canB-3n3kA:
19.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CAN_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3n3k UBIQUITIN
CARBOXYL-TERMINAL
HYDROLASE 8
(Homo
sapiens) 		4 / 7 TRP A1001
PHE A 946
GLU A 908
ARG A 944
 None
 1.49A 4canA-3n3kA:
undetectable
4canB-3n3kA:
undetectable		 4canA-3n3kA:
19.83
4canB-3n3kA:
19.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CAO_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3n3k UBIQUITIN
CARBOXYL-TERMINAL
HYDROLASE 8
(Homo
sapiens) 		4 / 7 ARG A 944
TRP A1001
PHE A 946
GLU A 908
 None
 1.45A 4caoA-3n3kA:
undetectable
4caoB-3n3kA:
undetectable		 4caoA-3n3kA:
19.83
4caoB-3n3kA:
19.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CAO_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3n3k UBIQUITIN
CARBOXYL-TERMINAL
HYDROLASE 8
(Homo
sapiens) 		4 / 7 TRP A1001
PHE A 946
GLU A 908
ARG A 944
 None
 1.49A 4caoA-3n3kA:
undetectable
4caoB-3n3kA:
undetectable		 4caoA-3n3kA:
19.83
4caoB-3n3kA:
19.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CAQ_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3n3k UBIQUITIN
CARBOXYL-TERMINAL
HYDROLASE 8
(Homo
sapiens) 		4 / 7 TRP A1001
PHE A 946
GLU A 908
ARG A 944
 None
 1.48A 4caqA-3n3kA:
undetectable
4caqB-3n3kA:
undetectable		 4caqA-3n3kA:
19.83
4caqB-3n3kA:
19.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CDT_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3n3k UBIQUITIN
CARBOXYL-TERMINAL
HYDROLASE 8
(Homo
sapiens) 		4 / 7 ARG A 944
TRP A1001
PHE A 946
GLU A 908
 None
 1.45A 4cdtA-3n3kA:
undetectable
4cdtB-3n3kA:
undetectable		 4cdtA-3n3kA:
19.83
4cdtB-3n3kA:
19.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CDT_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3n3k UBIQUITIN
CARBOXYL-TERMINAL
HYDROLASE 8
(Homo
sapiens) 		4 / 7 TRP A1001
PHE A 946
GLU A 908
ARG A 944
 None
 1.47A 4cdtA-3n3kA:
undetectable
4cdtB-3n3kA:
undetectable		 4cdtA-3n3kA:
19.83
4cdtB-3n3kA:
19.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CTP_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3n3k UBIQUITIN
CARBOXYL-TERMINAL
HYDROLASE 8
(Homo
sapiens) 		4 / 7 TRP A1001
PHE A 946
GLU A 908
ARG A 944
 None
 1.48A 4ctpA-3n3kA:
undetectable
4ctpB-3n3kA:
undetectable		 4ctpA-3n3kA:
19.83
4ctpB-3n3kA:
19.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CTQ_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3n3k UBIQUITIN
CARBOXYL-TERMINAL
HYDROLASE 8
(Homo
sapiens) 		4 / 7 TRP A1001
PHE A 946
GLU A 908
ARG A 944
 None
 1.47A 4ctqA-3n3kA:
undetectable
4ctqB-3n3kA:
undetectable		 4ctqA-3n3kA:
19.83
4ctqB-3n3kA:
19.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CTR_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3n3k UBIQUITIN
CARBOXYL-TERMINAL
HYDROLASE 8
(Homo
sapiens) 		4 / 7 TRP A1001
PHE A 946
GLU A 908
ARG A 944
 None
 1.48A 4ctrA-3n3kA:
undetectable
4ctrB-3n3kA:
undetectable		 4ctrA-3n3kA:
19.83
4ctrB-3n3kA:
19.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CTT_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3n3k UBIQUITIN
CARBOXYL-TERMINAL
HYDROLASE 8
(Homo
sapiens) 		4 / 7 ARG A 944
TRP A1001
PHE A 946
GLU A 908
 None
 1.50A 4cttA-3n3kA:
undetectable
4cttB-3n3kA:
undetectable		 4cttA-3n3kA:
19.83
4cttB-3n3kA:
19.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CTT_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3n3k UBIQUITIN
CARBOXYL-TERMINAL
HYDROLASE 8
(Homo
sapiens) 		4 / 7 TRP A1001
PHE A 946
GLU A 908
ARG A 944
 None
 1.43A 4cttA-3n3kA:
undetectable
4cttB-3n3kA:
undetectable		 4cttA-3n3kA:
19.83
4cttB-3n3kA:
19.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CTU_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3n3k UBIQUITIN
CARBOXYL-TERMINAL
HYDROLASE 8
(Homo
sapiens) 		4 / 7 ARG A 944
TRP A1001
PHE A 946
GLU A 908
 None
 1.50A 4ctuA-3n3kA:
undetectable
4ctuB-3n3kA:
undetectable		 4ctuA-3n3kA:
19.83
4ctuB-3n3kA:
19.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CTU_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3n3k UBIQUITIN
CARBOXYL-TERMINAL
HYDROLASE 8
(Homo
sapiens) 		4 / 7 TRP A1001
PHE A 946
GLU A 908
ARG A 944
 None
 1.44A 4ctuA-3n3kA:
undetectable
4ctuB-3n3kA:
undetectable		 4ctuA-3n3kA:
19.83
4ctuB-3n3kA:
19.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CTX_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3n3k UBIQUITIN
CARBOXYL-TERMINAL
HYDROLASE 8
(Homo
sapiens) 		4 / 7 TRP A1001
PHE A 946
GLU A 908
ARG A 944
 None
 1.50A 4ctxA-3n3kA:
undetectable
4ctxB-3n3kA:
undetectable		 4ctxA-3n3kA:
19.83
4ctxB-3n3kA:
19.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CTZ_A_H4BA600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 3n3k UBIQUITIN
CARBOXYL-TERMINAL
HYDROLASE 8
(Homo
sapiens) 		4 / 6 ARG A 944
TRP A1001
PHE A 946
GLU A 908
 None
 1.46A 4ctzA-3n3kA:
undetectable
4ctzB-3n3kA:
undetectable		 4ctzA-3n3kA:
21.73
4ctzB-3n3kA:
21.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CX5_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3n3k UBIQUITIN
CARBOXYL-TERMINAL
HYDROLASE 8
(Homo
sapiens) 		4 / 7 ARG A 944
TRP A1001
PHE A 946
GLU A 908
 None
 1.50A 4cx5A-3n3kA:
undetectable
4cx5B-3n3kA:
undetectable		 4cx5A-3n3kA:
19.83
4cx5B-3n3kA:
19.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CX5_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3n3k UBIQUITIN
CARBOXYL-TERMINAL
HYDROLASE 8
(Homo
sapiens) 		4 / 7 TRP A1001
PHE A 946
GLU A 908
ARG A 944
 None
 1.49A 4cx5A-3n3kA:
undetectable
4cx5B-3n3kA:
undetectable		 4cx5A-3n3kA:
19.83
4cx5B-3n3kA:
19.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CX6_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3n3k UBIQUITIN
CARBOXYL-TERMINAL
HYDROLASE 8
(Homo
sapiens) 		4 / 7 TRP A1001
PHE A 946
GLU A 908
ARG A 944
 None
 1.48A 4cx6A-3n3kA:
undetectable
4cx6B-3n3kA:
undetectable		 4cx6A-3n3kA:
19.83
4cx6B-3n3kA:
19.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CX7_D_H4BD600_1
(NITRIC OXIDE
SYNTHASE, INDUCIBLE)		 3n3k UBIQUITIN
CARBOXYL-TERMINAL
HYDROLASE 8
(Homo
sapiens) 		4 / 7 TRP A1001
PHE A 946
GLU A 908
ARG A 944
 None
 1.50A 4cx7C-3n3kA:
undetectable
4cx7D-3n3kA:
undetectable		 4cx7C-3n3kA:
21.13
4cx7D-3n3kA:
21.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D2Y_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3n3k UBIQUITIN
CARBOXYL-TERMINAL
HYDROLASE 8
(Homo
sapiens) 		4 / 7 TRP A1001
PHE A 946
GLU A 908
ARG A 944
 None
 1.48A 4d2yA-3n3kA:
undetectable
4d2yB-3n3kA:
undetectable		 4d2yA-3n3kA:
19.83
4d2yB-3n3kA:
19.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D2Z_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3n3k UBIQUITIN
CARBOXYL-TERMINAL
HYDROLASE 8
(Homo
sapiens) 		4 / 7 TRP A1001
PHE A 946
GLU A 908
ARG A 944
 None
 1.47A 4d2zA-3n3kA:
undetectable
4d2zB-3n3kA:
undetectable		 4d2zA-3n3kA:
19.83
4d2zB-3n3kA:
19.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D30_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3n3k UBIQUITIN
CARBOXYL-TERMINAL
HYDROLASE 8
(Homo
sapiens) 		4 / 7 TRP A1001
PHE A 946
GLU A 908
ARG A 944
 None
 1.45A 4d30A-3n3kA:
undetectable
4d30B-3n3kA:
undetectable		 4d30A-3n3kA:
19.83
4d30B-3n3kA:
19.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D31_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3n3k UBIQUITIN
CARBOXYL-TERMINAL
HYDROLASE 8
(Homo
sapiens) 		4 / 7 ARG A 944
TRP A1001
PHE A 946
GLU A 908
 None
 1.50A 4d31A-3n3kA:
undetectable
4d31B-3n3kA:
undetectable		 4d31A-3n3kA:
19.83
4d31B-3n3kA:
19.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D31_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3n3k UBIQUITIN
CARBOXYL-TERMINAL
HYDROLASE 8
(Homo
sapiens) 		4 / 7 TRP A1001
PHE A 946
GLU A 908
ARG A 944
 None
 1.46A 4d31A-3n3kA:
undetectable
4d31B-3n3kA:
undetectable		 4d31A-3n3kA:
19.83
4d31B-3n3kA:
19.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D3B_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3n3k UBIQUITIN
CARBOXYL-TERMINAL
HYDROLASE 8
(Homo
sapiens) 		4 / 7 TRP A1001
PHE A 946
GLU A 908
ARG A 944
 None
 1.49A 4d3bA-3n3kA:
undetectable
4d3bB-3n3kA:
undetectable		 4d3bA-3n3kA:
19.83
4d3bB-3n3kA:
19.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D7O_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3n3k UBIQUITIN
CARBOXYL-TERMINAL
HYDROLASE 8
(Homo
sapiens) 		4 / 7 TRP A1001
PHE A 946
GLU A 908
ARG A 944
 None
 1.49A 4d7oA-3n3kA:
undetectable
4d7oB-3n3kA:
undetectable		 4d7oA-3n3kA:
19.83
4d7oB-3n3kA:
19.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EUX_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3n3k UBIQUITIN
CARBOXYL-TERMINAL
HYDROLASE 8
(Homo
sapiens) 		4 / 7 TRP A1001
PHE A 946
GLU A 908
ARG A 944
 None
 1.44A 4euxA-3n3kA:
undetectable
4euxB-3n3kA:
undetectable		 4euxA-3n3kA:
19.83
4euxB-3n3kA:
19.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FVW_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3n3k UBIQUITIN
CARBOXYL-TERMINAL
HYDROLASE 8
(Homo
sapiens) 		4 / 7 TRP A1001
PHE A 946
GLU A 908
ARG A 944
 None
 1.48A 4fvwA-3n3kA:
undetectable
4fvwB-3n3kA:
undetectable		 4fvwA-3n3kA:
19.83
4fvwB-3n3kA:
19.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FVX_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3n3k UBIQUITIN
CARBOXYL-TERMINAL
HYDROLASE 8
(Homo
sapiens) 		4 / 7 TRP A1001
PHE A 946
GLU A 908
ARG A 944
 None
 1.47A 4fvxA-3n3kA:
undetectable
4fvxB-3n3kA:
undetectable		 4fvxA-3n3kA:
19.83
4fvxB-3n3kA:
19.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FVY_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3n3k UBIQUITIN
CARBOXYL-TERMINAL
HYDROLASE 8
(Homo
sapiens) 		4 / 7 TRP A1001
PHE A 946
GLU A 908
ARG A 944
 None
 1.50A 4fvyA-3n3kA:
undetectable
4fvyB-3n3kA:
undetectable		 4fvyA-3n3kA:
19.83
4fvyB-3n3kA:
19.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FW0_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3n3k UBIQUITIN
CARBOXYL-TERMINAL
HYDROLASE 8
(Homo
sapiens) 		4 / 7 TRP A1001
PHE A 946
GLU A 908
ARG A 944
 None
 1.49A 4fw0A-3n3kA:
undetectable
4fw0B-3n3kA:
undetectable		 4fw0A-3n3kA:
19.83
4fw0B-3n3kA:
19.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4GQE_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3n3k UBIQUITIN
CARBOXYL-TERMINAL
HYDROLASE 8
(Homo
sapiens) 		4 / 7 TRP A1001
PHE A 946
GLU A 908
ARG A 944
 None
 1.48A 4gqeA-3n3kA:
undetectable
4gqeB-3n3kA:
undetectable		 4gqeA-3n3kA:
19.83
4gqeB-3n3kA:
19.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IMT_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3n3k UBIQUITIN
CARBOXYL-TERMINAL
HYDROLASE 8
(Homo
sapiens) 		4 / 6 ARG A 944
TRP A1001
PHE A 946
GLU A 908
 None
 1.49A 4imtA-3n3kA:
undetectable
4imtB-3n3kA:
undetectable		 4imtA-3n3kA:
19.83
4imtB-3n3kA:
19.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IMT_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3n3k UBIQUITIN
CARBOXYL-TERMINAL
HYDROLASE 8
(Homo
sapiens) 		4 / 7 TRP A1001
PHE A 946
GLU A 908
ARG A 944
 None
 1.47A 4imtA-3n3kA:
undetectable
4imtB-3n3kA:
undetectable		 4imtA-3n3kA:
19.83
4imtB-3n3kA:
19.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JSF_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3n3k UBIQUITIN
CARBOXYL-TERMINAL
HYDROLASE 8
(Homo
sapiens) 		4 / 7 TRP A1001
PHE A 946
GLU A 908
ARG A 944
 None
 1.47A 4jsfA-3n3kA:
undetectable
4jsfB-3n3kA:
undetectable		 4jsfA-3n3kA:
19.83
4jsfB-3n3kA:
19.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JSH_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3n3k UBIQUITIN
CARBOXYL-TERMINAL
HYDROLASE 8
(Homo
sapiens) 		4 / 6 TRP A1001
PHE A 946
GLU A 908
ARG A 944
 None
 1.45A 4jshA-3n3kA:
undetectable
4jshB-3n3kA:
undetectable		 4jshA-3n3kA:
19.83
4jshB-3n3kA:
19.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JSI_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3n3k UBIQUITIN
CARBOXYL-TERMINAL
HYDROLASE 8
(Homo
sapiens) 		4 / 7 TRP A1001
PHE A 946
GLU A 908
ARG A 944
 None
 1.47A 4jsiA-3n3kA:
undetectable
4jsiB-3n3kA:
undetectable		 4jsiA-3n3kA:
19.83
4jsiB-3n3kA:
19.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JSJ_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3n3k UBIQUITIN
CARBOXYL-TERMINAL
HYDROLASE 8
(Homo
sapiens) 		4 / 7 TRP A1001
PHE A 946
GLU A 908
ARG A 944
 None
 1.48A 4jsjA-3n3kA:
undetectable
4jsjB-3n3kA:
undetectable		 4jsjA-3n3kA:
19.83
4jsjB-3n3kA:
19.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K5D_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3n3k UBIQUITIN
CARBOXYL-TERMINAL
HYDROLASE 8
(Homo
sapiens) 		4 / 7 TRP A1001
PHE A 946
GLU A 908
ARG A 944
 None
 1.46A 4k5dA-3n3kA:
undetectable
4k5dB-3n3kA:
undetectable		 4k5dA-3n3kA:
19.83
4k5dB-3n3kA:
19.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K5E_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3n3k UBIQUITIN
CARBOXYL-TERMINAL
HYDROLASE 8
(Homo
sapiens) 		4 / 6 TRP A1001
PHE A 946
GLU A 908
ARG A 944
 None
 1.49A 4k5eA-3n3kA:
undetectable
4k5eB-3n3kA:
undetectable		 4k5eA-3n3kA:
19.83
4k5eB-3n3kA:
19.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K5F_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3n3k UBIQUITIN
CARBOXYL-TERMINAL
HYDROLASE 8
(Homo
sapiens) 		4 / 7 ARG A 944
TRP A1001
PHE A 946
GLU A 908
 None
 1.49A 4k5fA-3n3kA:
undetectable
4k5fB-3n3kA:
undetectable		 4k5fA-3n3kA:
19.83
4k5fB-3n3kA:
19.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K5F_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3n3k UBIQUITIN
CARBOXYL-TERMINAL
HYDROLASE 8
(Homo
sapiens) 		4 / 7 TRP A1001
PHE A 946
GLU A 908
ARG A 944
 None
 1.46A 4k5fA-3n3kA:
undetectable
4k5fB-3n3kA:
undetectable		 4k5fA-3n3kA:
19.83
4k5fB-3n3kA:
19.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K5G_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3n3k UBIQUITIN
CARBOXYL-TERMINAL
HYDROLASE 8
(Homo
sapiens) 		4 / 7 ARG A 944
TRP A1001
PHE A 946
GLU A 908
 None
 1.50A 4k5gA-3n3kA:
undetectable
4k5gB-3n3kA:
undetectable		 4k5gA-3n3kA:
19.83
4k5gB-3n3kA:
19.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K5G_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3n3k UBIQUITIN
CARBOXYL-TERMINAL
HYDROLASE 8
(Homo
sapiens) 		4 / 7 TRP A1001
PHE A 946
GLU A 908
ARG A 944
 None
 1.48A 4k5gA-3n3kA:
undetectable
4k5gB-3n3kA:
undetectable		 4k5gA-3n3kA:
19.83
4k5gB-3n3kA:
19.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KCI_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3n3k UBIQUITIN
CARBOXYL-TERMINAL
HYDROLASE 8
(Homo
sapiens) 		4 / 7 TRP A1001
PHE A 946
GLU A 908
ARG A 944
 None
 1.49A 4kciA-3n3kA:
undetectable
4kciB-3n3kA:
undetectable		 4kciA-3n3kA:
19.83
4kciB-3n3kA:
19.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KCJ_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3n3k UBIQUITIN
CARBOXYL-TERMINAL
HYDROLASE 8
(Homo
sapiens) 		4 / 7 TRP A1001
PHE A 946
GLU A 908
ARG A 944
 None
 1.48A 4kcjA-3n3kA:
undetectable
4kcjB-3n3kA:
undetectable		 4kcjA-3n3kA:
19.83
4kcjB-3n3kA:
19.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KCK_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3n3k UBIQUITIN
CARBOXYL-TERMINAL
HYDROLASE 8
(Homo
sapiens) 		4 / 7 ARG A 944
TRP A1001
PHE A 946
GLU A 908
 None
 1.48A 4kckA-3n3kA:
undetectable
4kckB-3n3kA:
undetectable		 4kckA-3n3kA:
19.83
4kckB-3n3kA:
19.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KCK_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3n3k UBIQUITIN
CARBOXYL-TERMINAL
HYDROLASE 8
(Homo
sapiens) 		4 / 7 TRP A1001
PHE A 946
GLU A 908
ARG A 944
 None
 1.50A 4kckA-3n3kA:
undetectable
4kckB-3n3kA:
undetectable		 4kckA-3n3kA:
19.83
4kckB-3n3kA:
19.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KCM_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3n3k UBIQUITIN
CARBOXYL-TERMINAL
HYDROLASE 8
(Homo
sapiens) 		4 / 7 TRP A1001
PHE A 946
GLU A 908
ARG A 944
 None
 1.49A 4kcmA-3n3kA:
undetectable
4kcmB-3n3kA:
undetectable		 4kcmA-3n3kA:
19.83
4kcmB-3n3kA:
19.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KCN_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3n3k UBIQUITIN
CARBOXYL-TERMINAL
HYDROLASE 8
(Homo
sapiens) 		4 / 7 TRP A1001
PHE A 946
GLU A 908
ARG A 944
 None
 1.50A 4kcnA-3n3kA:
undetectable
4kcnB-3n3kA:
undetectable		 4kcnA-3n3kA:
19.83
4kcnB-3n3kA:
19.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KCO_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3n3k UBIQUITIN
CARBOXYL-TERMINAL
HYDROLASE 8
(Homo
sapiens) 		4 / 7 ARG A 944
TRP A1001
PHE A 946
GLU A 908
 None
 1.50A 4kcoA-3n3kA:
undetectable
4kcoB-3n3kA:
undetectable		 4kcoA-3n3kA:
19.83
4kcoB-3n3kA:
19.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L9Q_B_9TPB601_1
(SERUM ALBUMIN)		 3n3k UBIQUITIN
CARBOXYL-TERMINAL
HYDROLASE 8
(Homo
sapiens) 		5 / 12 ILE A 922
HIS A 881
LEU A 873
LEU A 876
GLY A 879
 None
 1.01A 4l9qB-3n3kA:
undetectable		 4l9qB-3n3kA:
20.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LUX_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3n3k UBIQUITIN
CARBOXYL-TERMINAL
HYDROLASE 8
(Homo
sapiens) 		4 / 7 ARG A 944
TRP A1001
PHE A 946
GLU A 908
 None
 1.48A 4luxA-3n3kA:
undetectable
4luxB-3n3kA:
undetectable		 4luxA-3n3kA:
19.83
4luxB-3n3kA:
19.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LUX_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3n3k UBIQUITIN
CARBOXYL-TERMINAL
HYDROLASE 8
(Homo
sapiens) 		4 / 7 TRP A1001
PHE A 946
GLU A 908
ARG A 944
 None
 1.48A 4luxA-3n3kA:
undetectable
4luxB-3n3kA:
undetectable		 4luxA-3n3kA:
19.83
4luxB-3n3kA:
19.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PWD_C_NVPC901_1
(HIV-1 REVERSE
TRANSCRIPTASE, P66
SUBUNIT)		 3n3k UBIQUITIN
CARBOXYL-TERMINAL
HYDROLASE 8
(Homo
sapiens) 		4 / 8 LEU A1104
VAL A1096
LEU A 964
TYR A1106
 None
 1.10A 4pwdC-3n3kA:
undetectable		 4pwdC-3n3kA:
22.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UCH_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3n3k UBIQUITIN
CARBOXYL-TERMINAL
HYDROLASE 8
(Homo
sapiens) 		4 / 7 ARG A 944
TRP A1001
PHE A 946
GLU A 908
 None
 1.46A 4uchA-3n3kA:
undetectable
4uchB-3n3kA:
undetectable		 4uchA-3n3kA:
20.26
4uchB-3n3kA:
20.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UCH_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3n3k UBIQUITIN
CARBOXYL-TERMINAL
HYDROLASE 8
(Homo
sapiens) 		4 / 8 TRP A1001
PHE A 946
GLU A 908
ARG A 944
 None
 1.48A 4uchA-3n3kA:
undetectable
4uchB-3n3kA:
undetectable		 4uchA-3n3kA:
20.26
4uchB-3n3kA:
20.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UGZ_B_H4BB760_1
(NEURONAL NITRIC
OXIDE SYNTHASE)		 3n3k UBIQUITIN
CARBOXYL-TERMINAL
HYDROLASE 8
(Homo
sapiens) 		4 / 7 TRP A1001
PHE A 946
GLU A 908
ARG A 944
 None
 1.49A 4ugzA-3n3kA:
undetectable
4ugzB-3n3kA:
undetectable		 4ugzA-3n3kA:
19.83
4ugzB-3n3kA:
19.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UH0_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3n3k UBIQUITIN
CARBOXYL-TERMINAL
HYDROLASE 8
(Homo
sapiens) 		4 / 7 ARG A 944
TRP A1001
PHE A 946
GLU A 908
 None
 1.50A 4uh0A-3n3kA:
undetectable
4uh0B-3n3kA:
undetectable		 4uh0A-3n3kA:
19.83
4uh0B-3n3kA:
19.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UH0_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3n3k UBIQUITIN
CARBOXYL-TERMINAL
HYDROLASE 8
(Homo
sapiens) 		4 / 7 TRP A1001
PHE A 946
GLU A 908
ARG A 944
 None
 1.48A 4uh0A-3n3kA:
undetectable
4uh0B-3n3kA:
undetectable		 4uh0A-3n3kA:
19.83
4uh0B-3n3kA:
19.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UH1_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3n3k UBIQUITIN
CARBOXYL-TERMINAL
HYDROLASE 8
(Homo
sapiens) 		4 / 6 TRP A1001
PHE A 946
GLU A 908
ARG A 944
 None
 1.47A 4uh1A-3n3kA:
undetectable
4uh1B-3n3kA:
undetectable		 4uh1A-3n3kA:
19.83
4uh1B-3n3kA:
19.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UH2_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3n3k UBIQUITIN
CARBOXYL-TERMINAL
HYDROLASE 8
(Homo
sapiens) 		4 / 7 TRP A1001
PHE A 946
GLU A 908
ARG A 944
 None
 1.45A 4uh2A-3n3kA:
undetectable
4uh2B-3n3kA:
undetectable		 4uh2A-3n3kA:
19.83
4uh2B-3n3kA:
19.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UH3_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3n3k UBIQUITIN
CARBOXYL-TERMINAL
HYDROLASE 8
(Homo
sapiens) 		4 / 7 TRP A1001
PHE A 946
GLU A 908
ARG A 944
 None
 1.44A 4uh3A-3n3kA:
undetectable
4uh3B-3n3kA:
undetectable		 4uh3A-3n3kA:
19.83
4uh3B-3n3kA:
19.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UH4_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3n3k UBIQUITIN
CARBOXYL-TERMINAL
HYDROLASE 8
(Homo
sapiens) 		4 / 7 TRP A1001
PHE A 946
GLU A 908
ARG A 944
 None
 1.48A 4uh4A-3n3kA:
undetectable
4uh4B-3n3kA:
undetectable		 4uh4A-3n3kA:
19.83
4uh4B-3n3kA:
19.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UH6_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3n3k UBIQUITIN
CARBOXYL-TERMINAL
HYDROLASE 8
(Homo
sapiens) 		4 / 7 TRP A1001
PHE A 946
GLU A 908
ARG A 944
 None
 1.49A 4uh6A-3n3kA:
undetectable
4uh6B-3n3kA:
undetectable		 4uh6A-3n3kA:
20.09
4uh6B-3n3kA:
20.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UPM_B_H4BB760_1
(NEURONAL NITRIC
OXIDE SYNTHASE)		 3n3k UBIQUITIN
CARBOXYL-TERMINAL
HYDROLASE 8
(Homo
sapiens) 		4 / 7 TRP A1001
PHE A 946
GLU A 908
ARG A 944
 None
 1.48A 4upmA-3n3kA:
undetectable
4upmB-3n3kA:
undetectable		 4upmA-3n3kA:
19.83
4upmB-3n3kA:
19.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UPN_A_H4BA760_1
(NEURONAL NITRIC
OXIDE SYNTHASE)		 3n3k UBIQUITIN
CARBOXYL-TERMINAL
HYDROLASE 8
(Homo
sapiens) 		4 / 7 ARG A 944
TRP A1001
PHE A 946
GLU A 908
 None
 1.47A 4upnA-3n3kA:
undetectable
4upnB-3n3kA:
undetectable		 4upnA-3n3kA:
19.83
4upnB-3n3kA:
19.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UPN_B_H4BB760_1
(NEURONAL NITRIC
OXIDE SYNTHASE)		 3n3k UBIQUITIN
CARBOXYL-TERMINAL
HYDROLASE 8
(Homo
sapiens) 		4 / 7 TRP A1001
PHE A 946
GLU A 908
ARG A 944
 None
 1.48A 4upnA-3n3kA:
undetectable
4upnB-3n3kA:
undetectable		 4upnA-3n3kA:
19.83
4upnB-3n3kA:
19.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UPO_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3n3k UBIQUITIN
CARBOXYL-TERMINAL
HYDROLASE 8
(Homo
sapiens) 		4 / 7 TRP A1001
PHE A 946
GLU A 908
ARG A 944
 None
 1.49A 4upoA-3n3kA:
undetectable
4upoB-3n3kA:
undetectable		 4upoA-3n3kA:
19.83
4upoB-3n3kA:
19.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V3U_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3n3k UBIQUITIN
CARBOXYL-TERMINAL
HYDROLASE 8
(Homo
sapiens) 		4 / 7 ARG A 944
TRP A1001
PHE A 946
GLU A 908
 None
 1.47A 4v3uA-3n3kA:
undetectable
4v3uB-3n3kA:
undetectable		 4v3uA-3n3kA:
19.91
4v3uB-3n3kA:
19.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V3U_C_H4BC760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3n3k UBIQUITIN
CARBOXYL-TERMINAL
HYDROLASE 8
(Homo
sapiens) 		4 / 7 ARG A 944
TRP A1001
PHE A 946
GLU A 908
 None
 1.48A 4v3uC-3n3kA:
undetectable
4v3uD-3n3kA:
undetectable		 4v3uC-3n3kA:
19.91
4v3uD-3n3kA:
19.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V3U_D_H4BD760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3n3k UBIQUITIN
CARBOXYL-TERMINAL
HYDROLASE 8
(Homo
sapiens) 		4 / 7 TRP A1001
PHE A 946
GLU A 908
ARG A 944
 None
 1.48A 4v3uC-3n3kA:
undetectable
4v3uD-3n3kA:
undetectable		 4v3uC-3n3kA:
19.91
4v3uD-3n3kA:
19.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V3X_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3n3k UBIQUITIN
CARBOXYL-TERMINAL
HYDROLASE 8
(Homo
sapiens) 		4 / 7 TRP A1001
PHE A 946
GLU A 908
ARG A 944
 None
 1.45A 4v3xA-3n3kA:
undetectable
4v3xB-3n3kA:
undetectable		 4v3xA-3n3kA:
19.83
4v3xB-3n3kA:
19.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V3Y_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3n3k UBIQUITIN
CARBOXYL-TERMINAL
HYDROLASE 8
(Homo
sapiens) 		4 / 7 ARG A 944
TRP A1001
PHE A 946
GLU A 908
 None
 1.49A 4v3yA-3n3kA:
undetectable
4v3yB-3n3kA:
undetectable		 4v3yA-3n3kA:
19.83
4v3yB-3n3kA:
19.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V3Z_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3n3k UBIQUITIN
CARBOXYL-TERMINAL
HYDROLASE 8
(Homo
sapiens) 		4 / 6 ARG A 944
TRP A1001
PHE A 946
GLU A 908
 None
 1.49A 4v3zA-3n3kA:
undetectable
4v3zB-3n3kA:
undetectable		 4v3zA-3n3kA:
19.83
4v3zB-3n3kA:
19.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V3Z_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3n3k UBIQUITIN
CARBOXYL-TERMINAL
HYDROLASE 8
(Homo
sapiens) 		4 / 7 TRP A1001
PHE A 946
GLU A 908
ARG A 944
 None
 1.41A 4v3zA-3n3kA:
undetectable
4v3zB-3n3kA:
undetectable		 4v3zA-3n3kA:
19.83
4v3zB-3n3kA:
19.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AD4_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3n3k UBIQUITIN
CARBOXYL-TERMINAL
HYDROLASE 8
(Homo
sapiens) 		4 / 7 TRP A1001
PHE A 946
GLU A 908
ARG A 944
 None
 1.48A 5ad4A-3n3kA:
undetectable
5ad4B-3n3kA:
undetectable		 5ad4A-3n3kA:
19.83
5ad4B-3n3kA:
19.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AD5_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3n3k UBIQUITIN
CARBOXYL-TERMINAL
HYDROLASE 8
(Homo
sapiens) 		4 / 7 ARG A 944
TRP A1001
PHE A 946
GLU A 908
 None
 1.47A 5ad5A-3n3kA:
undetectable
5ad5B-3n3kA:
undetectable		 5ad5A-3n3kA:
19.83
5ad5B-3n3kA:
19.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AD5_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3n3k UBIQUITIN
CARBOXYL-TERMINAL
HYDROLASE 8
(Homo
sapiens) 		4 / 6 TRP A1001
PHE A 946
GLU A 908
ARG A 944
 None
 1.46A 5ad5A-3n3kA:
undetectable
5ad5B-3n3kA:
undetectable		 5ad5A-3n3kA:
19.83
5ad5B-3n3kA:
19.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AD6_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3n3k UBIQUITIN
CARBOXYL-TERMINAL
HYDROLASE 8
(Homo
sapiens) 		4 / 7 ARG A 944
TRP A1001
PHE A 946
GLU A 908
 None
 1.49A 5ad6A-3n3kA:
undetectable
5ad6B-3n3kA:
undetectable		 5ad6A-3n3kA:
19.83
5ad6B-3n3kA:
19.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AD6_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3n3k UBIQUITIN
CARBOXYL-TERMINAL
HYDROLASE 8
(Homo
sapiens) 		4 / 7 TRP A1001
PHE A 946
GLU A 908
ARG A 944
 None
 1.45A 5ad6A-3n3kA:
undetectable
5ad6B-3n3kA:
undetectable		 5ad6A-3n3kA:
19.83
5ad6B-3n3kA:
19.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AD7_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3n3k UBIQUITIN
CARBOXYL-TERMINAL
HYDROLASE 8
(Homo
sapiens) 		4 / 6 TRP A1001
PHE A 946
GLU A 908
ARG A 944
 None
 1.48A 5ad7A-3n3kA:
undetectable
5ad7B-3n3kA:
undetectable		 5ad7A-3n3kA:
19.83
5ad7B-3n3kA:
19.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AD8_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3n3k UBIQUITIN
CARBOXYL-TERMINAL
HYDROLASE 8
(Homo
sapiens) 		4 / 6 TRP A1001
PHE A 946
GLU A 908
ARG A 944
 None
 1.44A 5ad8A-3n3kA:
undetectable
5ad8B-3n3kA:
undetectable		 5ad8A-3n3kA:
19.83
5ad8B-3n3kA:
19.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AD9_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3n3k UBIQUITIN
CARBOXYL-TERMINAL
HYDROLASE 8
(Homo
sapiens) 		4 / 7 ARG A 944
TRP A1001
PHE A 946
GLU A 908
 None
 1.44A 5ad9A-3n3kA:
undetectable
5ad9B-3n3kA:
undetectable		 5ad9A-3n3kA:
19.83
5ad9B-3n3kA:
19.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AD9_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3n3k UBIQUITIN
CARBOXYL-TERMINAL
HYDROLASE 8
(Homo
sapiens) 		4 / 6 TRP A1001
PHE A 946
GLU A 908
ARG A 944
 None
 1.41A 5ad9A-3n3kA:
undetectable
5ad9B-3n3kA:
undetectable		 5ad9A-3n3kA:
19.83
5ad9B-3n3kA:
19.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ADA_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3n3k UBIQUITIN
CARBOXYL-TERMINAL
HYDROLASE 8
(Homo
sapiens) 		4 / 7 ARG A 944
TRP A1001
PHE A 946
GLU A 908
 None
 1.47A 5adaA-3n3kA:
undetectable
5adaB-3n3kA:
undetectable		 5adaA-3n3kA:
19.83
5adaB-3n3kA:
19.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ADA_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3n3k UBIQUITIN
CARBOXYL-TERMINAL
HYDROLASE 8
(Homo
sapiens) 		4 / 7 TRP A1001
PHE A 946
GLU A 908
ARG A 944
 None
 1.48A 5adaA-3n3kA:
undetectable
5adaB-3n3kA:
undetectable		 5adaA-3n3kA:
19.83
5adaB-3n3kA:
19.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ADB_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3n3k UBIQUITIN
CARBOXYL-TERMINAL
HYDROLASE 8
(Homo
sapiens) 		4 / 6 TRP A1001
PHE A 946
GLU A 908
ARG A 944
 None
 1.39A 5adbA-3n3kA:
undetectable
5adbB-3n3kA:
undetectable		 5adbA-3n3kA:
19.83
5adbB-3n3kA:
19.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ADC_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3n3k UBIQUITIN
CARBOXYL-TERMINAL
HYDROLASE 8
(Homo
sapiens) 		4 / 6 ARG A 944
TRP A1001
PHE A 946
GLU A 908
 None
 1.49A 5adcA-3n3kA:
undetectable
5adcB-3n3kA:
undetectable		 5adcA-3n3kA:
19.83
5adcB-3n3kA:
19.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ADC_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3n3k UBIQUITIN
CARBOXYL-TERMINAL
HYDROLASE 8
(Homo
sapiens) 		4 / 7 TRP A1001
PHE A 946
GLU A 908
ARG A 944
 None
 1.44A 5adcA-3n3kA:
undetectable
5adcB-3n3kA:
undetectable		 5adcA-3n3kA:
19.83
5adcB-3n3kA:
19.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ADF_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3n3k UBIQUITIN
CARBOXYL-TERMINAL
HYDROLASE 8
(Homo
sapiens) 		4 / 7 ARG A 944
TRP A1001
PHE A 946
GLU A 908
 None
 1.48A 5adfA-3n3kA:
undetectable
5adfB-3n3kA:
undetectable		 5adfA-3n3kA:
20.09
5adfB-3n3kA:
20.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ADG_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3n3k UBIQUITIN
CARBOXYL-TERMINAL
HYDROLASE 8
(Homo
sapiens) 		4 / 7 ARG A 944
TRP A1001
PHE A 946
GLU A 908
 None
 1.46A 5adgA-3n3kA:
undetectable
5adgB-3n3kA:
undetectable		 5adgA-3n3kA:
20.09
5adgB-3n3kA:
20.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ADG_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3n3k UBIQUITIN
CARBOXYL-TERMINAL
HYDROLASE 8
(Homo
sapiens) 		4 / 7 TRP A1001
PHE A 946
GLU A 908
ARG A 944
 None
 1.49A 5adgA-3n3kA:
undetectable
5adgB-3n3kA:
undetectable		 5adgA-3n3kA:
20.09
5adgB-3n3kA:
20.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ADI_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3n3k UBIQUITIN
CARBOXYL-TERMINAL
HYDROLASE 8
(Homo
sapiens) 		4 / 7 ARG A 944
TRP A1001
PHE A 946
GLU A 908
 None
 1.43A 5adiA-3n3kA:
undetectable
5adiB-3n3kA:
undetectable		 5adiA-3n3kA:
20.09
5adiB-3n3kA:
20.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AGK_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3n3k UBIQUITIN
CARBOXYL-TERMINAL
HYDROLASE 8
(Homo
sapiens) 		4 / 7 ARG A 944
TRP A1001
PHE A 946
GLU A 908
 None
 1.45A 5agkA-3n3kA:
undetectable
5agkB-3n3kA:
undetectable		 5agkA-3n3kA:
19.83
5agkB-3n3kA:
19.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AGK_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3n3k UBIQUITIN
CARBOXYL-TERMINAL
HYDROLASE 8
(Homo
sapiens) 		4 / 7 TRP A1001
PHE A 946
GLU A 908
ARG A 944
 None
 1.44A 5agkA-3n3kA:
undetectable
5agkB-3n3kA:
undetectable		 5agkA-3n3kA:
19.83
5agkB-3n3kA:
19.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AGL_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3n3k UBIQUITIN
CARBOXYL-TERMINAL
HYDROLASE 8
(Homo
sapiens) 		4 / 7 TRP A1001
PHE A 946
GLU A 908
ARG A 944
 None
 1.47A 5aglA-3n3kA:
undetectable
5aglB-3n3kA:
undetectable		 5aglA-3n3kA:
19.83
5aglB-3n3kA:
19.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AGN_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3n3k UBIQUITIN
CARBOXYL-TERMINAL
HYDROLASE 8
(Homo
sapiens) 		4 / 7 TRP A1001
PHE A 946
GLU A 908
ARG A 944
 None
 1.47A 5agnA-3n3kA:
undetectable
5agnB-3n3kA:
undetectable		 5agnA-3n3kA:
19.83
5agnB-3n3kA:
19.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AGO_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3n3k UBIQUITIN
CARBOXYL-TERMINAL
HYDROLASE 8
(Homo
sapiens) 		4 / 7 ARG A 944
TRP A1001
PHE A 946
GLU A 908
 None
 1.48A 5agoA-3n3kA:
undetectable
5agoB-3n3kA:
undetectable		 5agoA-3n3kA:
19.83
5agoB-3n3kA:
19.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AGO_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3n3k UBIQUITIN
CARBOXYL-TERMINAL
HYDROLASE 8
(Homo
sapiens) 		4 / 7 TRP A1001
PHE A 946
GLU A 908
ARG A 944
 None
 1.44A 5agoA-3n3kA:
undetectable
5agoB-3n3kA:
undetectable		 5agoA-3n3kA:
19.83
5agoB-3n3kA:
19.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AGP_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3n3k UBIQUITIN
CARBOXYL-TERMINAL
HYDROLASE 8
(Homo
sapiens) 		4 / 7 TRP A1001
PHE A 946
GLU A 908
ARG A 944
 None
 1.48A 5agpA-3n3kA:
undetectable
5agpB-3n3kA:
undetectable		 5agpA-3n3kA:
19.83
5agpB-3n3kA:
19.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FVP_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3n3k UBIQUITIN
CARBOXYL-TERMINAL
HYDROLASE 8
(Homo
sapiens) 		4 / 6 TRP A1001
PHE A 946
GLU A 908
ARG A 944
 None
 1.43A 5fvpA-3n3kA:
undetectable
5fvpB-3n3kA:
undetectable		 5fvpA-3n3kA:
19.83
5fvpB-3n3kA:
19.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FVU_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3n3k UBIQUITIN
CARBOXYL-TERMINAL
HYDROLASE 8
(Homo
sapiens) 		4 / 7 TRP A1001
PHE A 946
GLU A 908
ARG A 944
 None
 1.48A 5fvuA-3n3kA:
undetectable
5fvuB-3n3kA:
undetectable		 5fvuA-3n3kA:
20.09
5fvuB-3n3kA:
20.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FVW_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3n3k UBIQUITIN
CARBOXYL-TERMINAL
HYDROLASE 8
(Homo
sapiens) 		4 / 7 ARG A 944
TRP A1001
PHE A 946
GLU A 908
 None
 1.48A 5fvwA-3n3kA:
undetectable
5fvwB-3n3kA:
undetectable		 5fvwA-3n3kA:
20.09
5fvwB-3n3kA:
20.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FW0_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3n3k UBIQUITIN
CARBOXYL-TERMINAL
HYDROLASE 8
(Homo
sapiens) 		4 / 7 TRP A1001
PHE A 946
GLU A 908
ARG A 944
 None
 1.50A 5fw0A-3n3kA:
undetectable
5fw0B-3n3kA:
undetectable		 5fw0A-3n3kA:
19.83
5fw0B-3n3kA:
19.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5G0N_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3n3k UBIQUITIN
CARBOXYL-TERMINAL
HYDROLASE 8
(Homo
sapiens) 		4 / 7 TRP A1001
PHE A 946
GLU A 908
ARG A 944
 None
 1.49A 5g0nA-3n3kA:
undetectable
5g0nB-3n3kA:
undetectable		 5g0nA-3n3kA:
20.89
5g0nB-3n3kA:
20.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5G0O_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3n3k UBIQUITIN
CARBOXYL-TERMINAL
HYDROLASE 8
(Homo
sapiens) 		4 / 7 TRP A1001
PHE A 946
GLU A 908
ARG A 944
 None
 1.45A 5g0oA-3n3kA:
undetectable
5g0oB-3n3kA:
undetectable		 5g0oA-3n3kA:
20.89
5g0oB-3n3kA:
20.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TL8_A_X2NA502_2
(PROTEIN CYP51)		 3n3k UBIQUITIN
CARBOXYL-TERMINAL
HYDROLASE 8
(Homo
sapiens) 		4 / 6 PRO A 799
LEU A1007
PHE A1105
LEU A1053
 None
 1.11A 5tl8A-3n3kA:
undetectable		 5tl8A-3n3kA:
23.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UNR_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3n3k UBIQUITIN
CARBOXYL-TERMINAL
HYDROLASE 8
(Homo
sapiens) 		4 / 7 TRP A1001
PHE A 946
GLU A 908
ARG A 944
 None
 1.45A 5unrA-3n3kA:
undetectable
5unrB-3n3kA:
undetectable		 5unrA-3n3kA:
19.83
5unrB-3n3kA:
19.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UNS_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3n3k UBIQUITIN
CARBOXYL-TERMINAL
HYDROLASE 8
(Homo
sapiens) 		4 / 6 ARG A 944
TRP A1001
PHE A 946
GLU A 908
 None
 1.50A 5unsA-3n3kA:
undetectable
5unsB-3n3kA:
undetectable		 5unsA-3n3kA:
19.83
5unsB-3n3kA:
19.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UNS_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3n3k UBIQUITIN
CARBOXYL-TERMINAL
HYDROLASE 8
(Homo
sapiens) 		4 / 7 TRP A1001
PHE A 946
GLU A 908
ARG A 944
 None
 1.50A 5unsA-3n3kA:
undetectable
5unsB-3n3kA:
undetectable		 5unsA-3n3kA:
19.83
5unsB-3n3kA:
19.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UNT_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3n3k UBIQUITIN
CARBOXYL-TERMINAL
HYDROLASE 8
(Homo
sapiens) 		4 / 7 TRP A1001
PHE A 946
GLU A 908
ARG A 944
 None
 1.45A 5untA-3n3kA:
undetectable
5untB-3n3kA:
undetectable		 5untA-3n3kA:
19.83
5untB-3n3kA:
19.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UNU_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3n3k UBIQUITIN
CARBOXYL-TERMINAL
HYDROLASE 8
(Homo
sapiens) 		4 / 7 ARG A 944
TRP A1001
PHE A 946
GLU A 908
 None
 1.48A 5unuA-3n3kA:
undetectable
5unuB-3n3kA:
undetectable		 5unuA-3n3kA:
19.83
5unuB-3n3kA:
19.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UNU_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3n3k UBIQUITIN
CARBOXYL-TERMINAL
HYDROLASE 8
(Homo
sapiens) 		4 / 7 TRP A1001
PHE A 946
GLU A 908
ARG A 944
 None
 1.38A 5unuA-3n3kA:
undetectable
5unuB-3n3kA:
undetectable		 5unuA-3n3kA:
19.83
5unuB-3n3kA:
19.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UNW_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3n3k UBIQUITIN
CARBOXYL-TERMINAL
HYDROLASE 8
(Homo
sapiens) 		4 / 7 ARG A 944
TRP A1001
PHE A 946
GLU A 908
 None
 1.49A 5unwA-3n3kA:
undetectable
5unwB-3n3kA:
undetectable		 5unwA-3n3kA:
19.83
5unwB-3n3kA:
19.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UNW_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3n3k UBIQUITIN
CARBOXYL-TERMINAL
HYDROLASE 8
(Homo
sapiens) 		4 / 7 TRP A1001
PHE A 946
GLU A 908
ARG A 944
 None
 1.38A 5unwA-3n3kA:
undetectable
5unwB-3n3kA:
undetectable		 5unwA-3n3kA:
19.83
5unwB-3n3kA:
19.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UNX_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3n3k UBIQUITIN
CARBOXYL-TERMINAL
HYDROLASE 8
(Homo
sapiens) 		4 / 6 TRP A1001
PHE A 946
GLU A 908
ARG A 944
 None
 1.41A 5unxA-3n3kA:
undetectable
5unxB-3n3kA:
undetectable		 5unxA-3n3kA:
19.83
5unxB-3n3kA:
19.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UNY_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3n3k UBIQUITIN
CARBOXYL-TERMINAL
HYDROLASE 8
(Homo
sapiens) 		4 / 7 ARG A 944
TRP A1001
PHE A 946
GLU A 908
 None
 1.48A 5unyA-3n3kA:
undetectable
5unyB-3n3kA:
undetectable		 5unyA-3n3kA:
19.83
5unyB-3n3kA:
19.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UNY_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3n3k UBIQUITIN
CARBOXYL-TERMINAL
HYDROLASE 8
(Homo
sapiens) 		4 / 7 TRP A1001
PHE A 946
GLU A 908
ARG A 944
 None
 1.45A 5unyA-3n3kA:
undetectable
5unyB-3n3kA:
undetectable		 5unyA-3n3kA:
19.83
5unyB-3n3kA:
19.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UNZ_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3n3k UBIQUITIN
CARBOXYL-TERMINAL
HYDROLASE 8
(Homo
sapiens) 		4 / 7 TRP A1001
PHE A 946
GLU A 908
ARG A 944
 None
 1.46A 5unzA-3n3kA:
undetectable
5unzB-3n3kA:
undetectable		 5unzA-3n3kA:
19.83
5unzB-3n3kA:
19.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UO0_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3n3k UBIQUITIN
CARBOXYL-TERMINAL
HYDROLASE 8
(Homo
sapiens) 		4 / 7 TRP A1001
PHE A 946
GLU A 908
ARG A 944
 None
 1.47A 5uo0A-3n3kA:
undetectable
5uo0B-3n3kA:
undetectable		 5uo0A-3n3kA:
19.83
5uo0B-3n3kA:
19.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UO1_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3n3k UBIQUITIN
CARBOXYL-TERMINAL
HYDROLASE 8
(Homo
sapiens) 		4 / 7 ARG A 944
TRP A1001
PHE A 946
GLU A 908
 None
 1.46A 5uo1A-3n3kA:
undetectable
5uo1B-3n3kA:
undetectable		 5uo1A-3n3kA:
20.09
5uo1B-3n3kA:
20.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UO1_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3n3k UBIQUITIN
CARBOXYL-TERMINAL
HYDROLASE 8
(Homo
sapiens) 		4 / 7 TRP A1001
PHE A 946
GLU A 908
ARG A 944
 None
 1.49A 5uo1A-3n3kA:
undetectable
5uo1B-3n3kA:
undetectable		 5uo1A-3n3kA:
20.09
5uo1B-3n3kA:
20.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UO2_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3n3k UBIQUITIN
CARBOXYL-TERMINAL
HYDROLASE 8
(Homo
sapiens) 		4 / 7 ARG A 944
TRP A1001
PHE A 946
GLU A 908
 None
 1.49A 5uo2A-3n3kA:
undetectable
5uo2B-3n3kA:
undetectable		 5uo2A-3n3kA:
20.09
5uo2B-3n3kA:
20.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UO3_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3n3k UBIQUITIN
CARBOXYL-TERMINAL
HYDROLASE 8
(Homo
sapiens) 		4 / 7 ARG A 944
TRP A1001
PHE A 946
GLU A 908
 None
 1.43A 5uo3A-3n3kA:
undetectable
5uo3B-3n3kA:
undetectable		 5uo3A-3n3kA:
20.09
5uo3B-3n3kA:
20.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UO4_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3n3k UBIQUITIN
CARBOXYL-TERMINAL
HYDROLASE 8
(Homo
sapiens) 		4 / 7 ARG A 944
TRP A1001
PHE A 946
GLU A 908
 None
 1.44A 5uo4A-3n3kA:
undetectable
5uo4B-3n3kA:
undetectable		 5uo4A-3n3kA:
20.09
5uo4B-3n3kA:
20.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UO4_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3n3k UBIQUITIN
CARBOXYL-TERMINAL
HYDROLASE 8
(Homo
sapiens) 		4 / 7 TRP A1001
PHE A 946
GLU A 908
ARG A 944
 None
 1.47A 5uo4A-3n3kA:
undetectable
5uo4B-3n3kA:
undetectable		 5uo4A-3n3kA:
20.09
5uo4B-3n3kA:
20.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UO5_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3n3k UBIQUITIN
CARBOXYL-TERMINAL
HYDROLASE 8
(Homo
sapiens) 		4 / 7 ARG A 944
TRP A1001
PHE A 946
GLU A 908
 None
 1.46A 5uo5A-3n3kA:
undetectable
5uo5B-3n3kA:
undetectable		 5uo5A-3n3kA:
20.09
5uo5B-3n3kA:
20.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UO5_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3n3k UBIQUITIN
CARBOXYL-TERMINAL
HYDROLASE 8
(Homo
sapiens) 		4 / 7 TRP A1001
PHE A 946
GLU A 908
ARG A 944
 None
 1.48A 5uo5A-3n3kA:
undetectable
5uo5B-3n3kA:
undetectable		 5uo5A-3n3kA:
20.09
5uo5B-3n3kA:
20.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UO6_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3n3k UBIQUITIN
CARBOXYL-TERMINAL
HYDROLASE 8
(Homo
sapiens) 		4 / 7 TRP A1001
PHE A 946
GLU A 908
ARG A 944
 None
 1.46A 5uo6A-3n3kA:
undetectable
5uo6B-3n3kA:
undetectable		 5uo6A-3n3kA:
20.09
5uo6B-3n3kA:
20.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UO7_B_H4BB803_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3n3k UBIQUITIN
CARBOXYL-TERMINAL
HYDROLASE 8
(Homo
sapiens) 		4 / 7 TRP A1001
PHE A 946
GLU A 908
ARG A 944
 None
 1.45A 5uo7A-3n3kA:
undetectable
5uo7B-3n3kA:
undetectable		 5uo7A-3n3kA:
20.09
5uo7B-3n3kA:
20.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUI_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3n3k UBIQUITIN
CARBOXYL-TERMINAL
HYDROLASE 8
(Homo
sapiens) 		4 / 7 TRP A1001
PHE A 946
GLU A 908
ARG A 944
 None
 1.48A 5vuiA-3n3kA:
undetectable
5vuiB-3n3kA:
undetectable		 5vuiA-3n3kA:
19.83
5vuiB-3n3kA:
19.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUK_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3n3k UBIQUITIN
CARBOXYL-TERMINAL
HYDROLASE 8
(Homo
sapiens) 		4 / 7 ARG A 944
TRP A1001
PHE A 946
GLU A 908
 None
 1.50A 5vukA-3n3kA:
undetectable
5vukB-3n3kA:
undetectable		 5vukA-3n3kA:
19.83
5vukB-3n3kA:
19.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUK_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3n3k UBIQUITIN
CARBOXYL-TERMINAL
HYDROLASE 8
(Homo
sapiens) 		4 / 7 TRP A1001
PHE A 946
GLU A 908
ARG A 944
 None
 1.46A 5vukA-3n3kA:
undetectable
5vukB-3n3kA:
undetectable		 5vukA-3n3kA:
19.83
5vukB-3n3kA:
19.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUL_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3n3k UBIQUITIN
CARBOXYL-TERMINAL
HYDROLASE 8
(Homo
sapiens) 		4 / 7 TRP A1001
PHE A 946
GLU A 908
ARG A 944
 None
 1.49A 5vulA-3n3kA:
undetectable
5vulB-3n3kA:
undetectable		 5vulA-3n3kA:
19.83
5vulB-3n3kA:
19.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUM_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3n3k UBIQUITIN
CARBOXYL-TERMINAL
HYDROLASE 8
(Homo
sapiens) 		4 / 7 TRP A1001
PHE A 946
GLU A 908
ARG A 944
 None
 1.49A 5vumA-3n3kA:
undetectable
5vumB-3n3kA:
undetectable		 5vumA-3n3kA:
19.83
5vumB-3n3kA:
19.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUN_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3n3k UBIQUITIN
CARBOXYL-TERMINAL
HYDROLASE 8
(Homo
sapiens) 		4 / 7 TRP A1001
PHE A 946
GLU A 908
ARG A 944
 None
 1.49A 5vunA-3n3kA:
undetectable
5vunB-3n3kA:
undetectable		 5vunA-3n3kA:
19.83
5vunB-3n3kA:
19.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUO_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3n3k UBIQUITIN
CARBOXYL-TERMINAL
HYDROLASE 8
(Homo
sapiens) 		4 / 7 TRP A1001
PHE A 946
GLU A 908
ARG A 944
 None
 1.48A 5vuoA-3n3kA:
undetectable
5vuoB-3n3kA:
undetectable		 5vuoA-3n3kA:
19.83
5vuoB-3n3kA:
19.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUQ_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3n3k UBIQUITIN
CARBOXYL-TERMINAL
HYDROLASE 8
(Homo
sapiens) 		4 / 7 TRP A1001
PHE A 946
GLU A 908
ARG A 944
 None
 1.49A 5vuqA-3n3kA:
undetectable
5vuqB-3n3kA:
undetectable		 5vuqA-3n3kA:
19.83
5vuqB-3n3kA:
19.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUR_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3n3k UBIQUITIN
CARBOXYL-TERMINAL
HYDROLASE 8
(Homo
sapiens) 		4 / 7 TRP A1001
PHE A 946
GLU A 908
ARG A 944
 None
 1.43A 5vurA-3n3kA:
undetectable
5vurB-3n3kA:
undetectable		 5vurA-3n3kA:
19.83
5vurB-3n3kA:
19.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUS_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3n3k UBIQUITIN
CARBOXYL-TERMINAL
HYDROLASE 8
(Homo
sapiens) 		4 / 7 ARG A 944
TRP A1001
PHE A 946
GLU A 908
 None
 1.45A 5vusA-3n3kA:
undetectable
5vusB-3n3kA:
undetectable		 5vusA-3n3kA:
19.83
5vusB-3n3kA:
19.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUS_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3n3k UBIQUITIN
CARBOXYL-TERMINAL
HYDROLASE 8
(Homo
sapiens) 		4 / 7 TRP A1001
PHE A 946
GLU A 908
ARG A 944
 None
 1.48A 5vusA-3n3kA:
undetectable
5vusB-3n3kA:
undetectable		 5vusA-3n3kA:
19.83
5vusB-3n3kA:
19.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUT_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3n3k UBIQUITIN
CARBOXYL-TERMINAL
HYDROLASE 8
(Homo
sapiens) 		4 / 7 TRP A1001
PHE A 946
GLU A 908
ARG A 944
 None
 1.48A 5vutA-3n3kA:
undetectable
5vutB-3n3kA:
undetectable		 5vutA-3n3kA:
19.83
5vutB-3n3kA:
19.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUU_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3n3k UBIQUITIN
CARBOXYL-TERMINAL
HYDROLASE 8
(Homo
sapiens) 		4 / 7 ARG A 944
TRP A1001
PHE A 946
GLU A 908
 None
 1.49A 5vuuA-3n3kA:
undetectable
5vuuB-3n3kA:
undetectable		 5vuuA-3n3kA:
19.83
5vuuB-3n3kA:
19.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUU_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3n3k UBIQUITIN
CARBOXYL-TERMINAL
HYDROLASE 8
(Homo
sapiens) 		4 / 7 TRP A1001
PHE A 946
GLU A 908
ARG A 944
 None
 1.48A 5vuuA-3n3kA:
undetectable
5vuuB-3n3kA:
undetectable		 5vuuA-3n3kA:
19.83
5vuuB-3n3kA:
19.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUV_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3n3k UBIQUITIN
CARBOXYL-TERMINAL
HYDROLASE 8
(Homo
sapiens) 		4 / 7 ARG A 944
TRP A1001
PHE A 946
GLU A 908
 None
 1.47A 5vuvA-3n3kA:
undetectable
5vuvB-3n3kA:
undetectable		 5vuvA-3n3kA:
20.09
5vuvB-3n3kA:
20.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUV_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3n3k UBIQUITIN
CARBOXYL-TERMINAL
HYDROLASE 8
(Homo
sapiens) 		4 / 7 TRP A1001
PHE A 946
GLU A 908
ARG A 944
 None
 1.49A 5vuvA-3n3kA:
undetectable
5vuvB-3n3kA:
undetectable		 5vuvA-3n3kA:
20.09
5vuvB-3n3kA:
20.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUW_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3n3k UBIQUITIN
CARBOXYL-TERMINAL
HYDROLASE 8
(Homo
sapiens) 		4 / 7 ARG A 944
TRP A1001
PHE A 946
GLU A 908
 None
 1.49A 5vuwA-3n3kA:
undetectable
5vuwB-3n3kA:
undetectable		 5vuwA-3n3kA:
20.09
5vuwB-3n3kA:
20.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUX_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3n3k UBIQUITIN
CARBOXYL-TERMINAL
HYDROLASE 8
(Homo
sapiens) 		4 / 7 ARG A 944
TRP A1001
PHE A 946
GLU A 908
 None
 1.49A 5vuxA-3n3kA:
undetectable
5vuxB-3n3kA:
undetectable		 5vuxA-3n3kA:
20.09
5vuxB-3n3kA:
20.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUY_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3n3k UBIQUITIN
CARBOXYL-TERMINAL
HYDROLASE 8
(Homo
sapiens) 		4 / 7 ARG A 944
TRP A1001
PHE A 946
GLU A 908
 None
 1.49A 5vuyA-3n3kA:
undetectable
5vuyB-3n3kA:
undetectable		 5vuyA-3n3kA:
20.09
5vuyB-3n3kA:
20.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUY_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3n3k UBIQUITIN
CARBOXYL-TERMINAL
HYDROLASE 8
(Homo
sapiens) 		4 / 7 TRP A1001
PHE A 946
GLU A 908
ARG A 944
 None
 1.44A 5vuyA-3n3kA:
undetectable
5vuyB-3n3kA:
undetectable		 5vuyA-3n3kA:
20.09
5vuyB-3n3kA:
20.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUZ_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3n3k UBIQUITIN
CARBOXYL-TERMINAL
HYDROLASE 8
(Homo
sapiens) 		4 / 7 ARG A 944
TRP A1001
PHE A 946
GLU A 908
 None
 1.48A 5vuzA-3n3kA:
undetectable
5vuzB-3n3kA:
undetectable		 5vuzA-3n3kA:
20.09
5vuzB-3n3kA:
20.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUZ_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3n3k UBIQUITIN
CARBOXYL-TERMINAL
HYDROLASE 8
(Homo
sapiens) 		4 / 7 TRP A1001
PHE A 946
GLU A 908
ARG A 944
 None
 1.49A 5vuzA-3n3kA:
undetectable
5vuzB-3n3kA:
undetectable		 5vuzA-3n3kA:
20.09
5vuzB-3n3kA:
20.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VV0_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3n3k UBIQUITIN
CARBOXYL-TERMINAL
HYDROLASE 8
(Homo
sapiens) 		4 / 6 ARG A 944
TRP A1001
PHE A 946
GLU A 908
 None
 1.47A 5vv0A-3n3kA:
undetectable
5vv0B-3n3kA:
undetectable		 5vv0A-3n3kA:
20.09
5vv0B-3n3kA:
20.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VV0_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3n3k UBIQUITIN
CARBOXYL-TERMINAL
HYDROLASE 8
(Homo
sapiens) 		4 / 6 TRP A1001
PHE A 946
GLU A 908
ARG A 944
 None
 1.48A 5vv0A-3n3kA:
undetectable
5vv0B-3n3kA:
undetectable		 5vv0A-3n3kA:
20.09
5vv0B-3n3kA:
20.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VV1_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3n3k UBIQUITIN
CARBOXYL-TERMINAL
HYDROLASE 8
(Homo
sapiens) 		4 / 6 ARG A 944
TRP A1001
PHE A 946
GLU A 908
 None
 1.46A 5vv1A-3n3kA:
undetectable
5vv1B-3n3kA:
undetectable		 5vv1A-3n3kA:
20.09
5vv1B-3n3kA:
20.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VV1_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3n3k UBIQUITIN
CARBOXYL-TERMINAL
HYDROLASE 8
(Homo
sapiens) 		4 / 6 TRP A1001
PHE A 946
GLU A 908
ARG A 944
 None
 1.49A 5vv1A-3n3kA:
undetectable
5vv1B-3n3kA:
undetectable		 5vv1A-3n3kA:
20.09
5vv1B-3n3kA:
20.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VV2_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3n3k UBIQUITIN
CARBOXYL-TERMINAL
HYDROLASE 8
(Homo
sapiens) 		4 / 7 ARG A 944
TRP A1001
PHE A 946
GLU A 908
 None
 1.46A 5vv2A-3n3kA:
undetectable
5vv2B-3n3kA:
undetectable		 5vv2A-3n3kA:
20.09
5vv2B-3n3kA:
20.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VV3_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3n3k UBIQUITIN
CARBOXYL-TERMINAL
HYDROLASE 8
(Homo
sapiens) 		4 / 7 ARG A 944
TRP A1001
PHE A 946
GLU A 908
 None
 1.47A 5vv3A-3n3kA:
undetectable
5vv3B-3n3kA:
undetectable		 5vv3A-3n3kA:
20.09
5vv3B-3n3kA:
20.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VV3_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3n3k UBIQUITIN
CARBOXYL-TERMINAL
HYDROLASE 8
(Homo
sapiens) 		4 / 7 TRP A1001
PHE A 946
GLU A 908
ARG A 944
 None
 1.48A 5vv3A-3n3kA:
undetectable
5vv3B-3n3kA:
undetectable		 5vv3A-3n3kA:
20.09
5vv3B-3n3kA:
20.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VV4_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3n3k UBIQUITIN
CARBOXYL-TERMINAL
HYDROLASE 8
(Homo
sapiens) 		4 / 7 TRP A1001
PHE A 946
GLU A 908
ARG A 944
 None
 1.48A 5vv4A-3n3kA:
undetectable
5vv4B-3n3kA:
undetectable		 5vv4A-3n3kA:
20.09
5vv4B-3n3kA:
20.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VV5_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3n3k UBIQUITIN
CARBOXYL-TERMINAL
HYDROLASE 8
(Homo
sapiens) 		4 / 7 TRP A1001
PHE A 946
GLU A 908
ARG A 944
 None
 1.43A 5vv5A-3n3kA:
undetectable
5vv5B-3n3kA:
undetectable		 5vv5A-3n3kA:
20.09
5vv5B-3n3kA:
20.09
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5XU8_A_DX4A701_0
(UBIQUITIN
CARBOXYL-TERMINAL
HYDROLASE 2)		 3n3k UBIQUITIN
CARBOXYL-TERMINAL
HYDROLASE 8
(Homo
sapiens) 		7 / 8 GLY A 778
LEU A 779
ASN A 789
SER A 790
GLN A 793
ALA A1070
PHE A1083
 None
 0.34A 5xu8A-3n3kA:
41.2		 5xu8A-3n3kA:
38.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AUQ_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3n3k UBIQUITIN
CARBOXYL-TERMINAL
HYDROLASE 8
(Homo
sapiens) 		4 / 7 TRP A1001
PHE A 946
GLU A 908
ARG A 944
 None
 1.44A 6auqA-3n3kA:
undetectable
6auqB-3n3kA:
undetectable		 6auqA-3n3kA:
10.53
6auqB-3n3kA:
10.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AUR_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3n3k UBIQUITIN
CARBOXYL-TERMINAL
HYDROLASE 8
(Homo
sapiens) 		4 / 7 TRP A1001
PHE A 946
GLU A 908
ARG A 944
 None
 1.49A 6aurA-3n3kA:
undetectable
6aurB-3n3kA:
undetectable		 6aurA-3n3kA:
10.53
6aurB-3n3kA:
10.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AUT_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3n3k UBIQUITIN
CARBOXYL-TERMINAL
HYDROLASE 8
(Homo
sapiens) 		4 / 7 TRP A1001
PHE A 946
GLU A 908
ARG A 944
 None
 1.47A 6autA-3n3kA:
undetectable
6autB-3n3kA:
undetectable		 6autA-3n3kA:
10.53
6autB-3n3kA:
10.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AUU_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3n3k UBIQUITIN
CARBOXYL-TERMINAL
HYDROLASE 8
(Homo
sapiens) 		4 / 7 ARG A 944
TRP A1001
PHE A 946
GLU A 908
 None
 1.48A 6auuA-3n3kA:
undetectable
6auuB-3n3kA:
undetectable		 6auuA-3n3kA:
10.53
6auuB-3n3kA:
10.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AUU_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3n3k UBIQUITIN
CARBOXYL-TERMINAL
HYDROLASE 8
(Homo
sapiens) 		4 / 7 TRP A1001
PHE A 946
GLU A 908
ARG A 944
 None
 1.44A 6auuA-3n3kA:
undetectable
6auuB-3n3kA:
undetectable		 6auuA-3n3kA:
10.53
6auuB-3n3kA:
10.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AUV_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3n3k UBIQUITIN
CARBOXYL-TERMINAL
HYDROLASE 8
(Homo
sapiens) 		4 / 7 TRP A1001
PHE A 946
GLU A 908
ARG A 944
 None
 1.49A 6auvA-3n3kA:
undetectable
6auvB-3n3kA:
undetectable		 6auvA-3n3kA:
10.53
6auvB-3n3kA:
10.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AUW_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3n3k UBIQUITIN
CARBOXYL-TERMINAL
HYDROLASE 8
(Homo
sapiens) 		4 / 7 TRP A1001
PHE A 946
GLU A 908
ARG A 944
 None
 1.46A 6auwA-3n3kA:
undetectable
6auwB-3n3kA:
undetectable		 6auwA-3n3kA:
10.53
6auwB-3n3kA:
10.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AUX_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3n3k UBIQUITIN
CARBOXYL-TERMINAL
HYDROLASE 8
(Homo
sapiens) 		4 / 7 ARG A 944
TRP A1001
PHE A 946
GLU A 908
 None
 1.47A 6auxA-3n3kA:
undetectable
6auxB-3n3kA:
undetectable		 6auxA-3n3kA:
10.53
6auxB-3n3kA:
10.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AUX_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3n3k UBIQUITIN
CARBOXYL-TERMINAL
HYDROLASE 8
(Homo
sapiens) 		4 / 7 TRP A1001
PHE A 946
GLU A 908
ARG A 944
 None
 1.45A 6auxA-3n3kA:
undetectable
6auxB-3n3kA:
undetectable		 6auxA-3n3kA:
10.53
6auxB-3n3kA:
10.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AUY_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3n3k UBIQUITIN
CARBOXYL-TERMINAL
HYDROLASE 8
(Homo
sapiens) 		4 / 7 ARG A 944
TRP A1001
PHE A 946
GLU A 908
 None
 1.46A 6auyA-3n3kA:
undetectable
6auyB-3n3kA:
undetectable		 6auyA-3n3kA:
11.11
6auyB-3n3kA:
11.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AV0_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3n3k UBIQUITIN
CARBOXYL-TERMINAL
HYDROLASE 8
(Homo
sapiens) 		4 / 7 ARG A 944
TRP A1001
PHE A 946
GLU A 908
 None
 1.48A 6av0A-3n3kA:
undetectable
6av0B-3n3kA:
undetectable		 6av0A-3n3kA:
11.11
6av0B-3n3kA:
11.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AV1_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3n3k UBIQUITIN
CARBOXYL-TERMINAL
HYDROLASE 8
(Homo
sapiens) 		4 / 7 ARG A 944
TRP A1001
PHE A 946
GLU A 908
 None
 1.49A 6av1A-3n3kA:
undetectable
6av1B-3n3kA:
undetectable		 6av1A-3n3kA:
11.11
6av1B-3n3kA:
11.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AV1_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3n3k UBIQUITIN
CARBOXYL-TERMINAL
HYDROLASE 8
(Homo
sapiens) 		4 / 7 TRP A1001
PHE A 946
GLU A 908
ARG A 944
 None
 1.48A 6av1A-3n3kA:
undetectable
6av1B-3n3kA:
undetectable		 6av1A-3n3kA:
11.11
6av1B-3n3kA:
11.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AV2_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3n3k UBIQUITIN
CARBOXYL-TERMINAL
HYDROLASE 8
(Homo
sapiens) 		4 / 7 ARG A 944
TRP A1001
PHE A 946
GLU A 908
 None
 1.47A 6av2A-3n3kA:
undetectable
6av2B-3n3kA:
undetectable		 6av2A-3n3kA:
11.11
6av2B-3n3kA:
11.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AV3_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3n3k UBIQUITIN
CARBOXYL-TERMINAL
HYDROLASE 8
(Homo
sapiens) 		4 / 7 ARG A 944
TRP A1001
PHE A 946
GLU A 908
 None
 1.50A 6av3A-3n3kA:
undetectable
6av3B-3n3kA:
undetectable		 6av3A-3n3kA:
11.11
6av3B-3n3kA:
11.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AV4_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3n3k UBIQUITIN
CARBOXYL-TERMINAL
HYDROLASE 8
(Homo
sapiens) 		4 / 7 ARG A 944
TRP A1001
PHE A 946
GLU A 908
 None
 1.49A 6av4A-3n3kA:
undetectable
6av4B-3n3kA:
undetectable		 6av4A-3n3kA:
11.11
6av4B-3n3kA:
11.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AV4_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3n3k UBIQUITIN
CARBOXYL-TERMINAL
HYDROLASE 8
(Homo
sapiens) 		4 / 7 TRP A1001
PHE A 946
GLU A 908
ARG A 944
 None
 1.50A 6av4A-3n3kA:
undetectable
6av4B-3n3kA:
undetectable		 6av4A-3n3kA:
11.11
6av4B-3n3kA:
11.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AV5_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3n3k UBIQUITIN
CARBOXYL-TERMINAL
HYDROLASE 8
(Homo
sapiens) 		4 / 7 ARG A 944
TRP A1001
PHE A 946
GLU A 908
 None
 1.48A 6av5A-3n3kA:
undetectable
6av5B-3n3kA:
undetectable		 6av5A-3n3kA:
11.11
6av5B-3n3kA:
11.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BP4_A_SAMA505_1
(HISTONE-LYSINE
N-METHYLTRANSFERASE,
H3 LYSINE-9 SPECIFIC)		 3n3k UBIQUITIN
CARBOXYL-TERMINAL
HYDROLASE 8
(Homo
sapiens) 		3 / 3 ILE A 854
ASN A 789
CYH A 794
 None
 0.93A 6bp4A-3n3kA:
undetectable		 6bp4A-3n3kA:
19.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CIC_A_H4BA802_0
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3n3k UBIQUITIN
CARBOXYL-TERMINAL
HYDROLASE 8
(Homo
sapiens) 		4 / 7 ARG A 944
TRP A1001
PHE A 946
GLU A 908
 None
 1.49A 6cicA-3n3kA:
undetectable
6cicB-3n3kA:
undetectable		 6cicA-3n3kA:
11.11
6cicB-3n3kA:
11.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CIC_B_H4BB802_0
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3n3k UBIQUITIN
CARBOXYL-TERMINAL
HYDROLASE 8
(Homo
sapiens) 		4 / 7 TRP A1001
PHE A 946
GLU A 908
ARG A 944
 None
 1.47A 6cicA-3n3kA:
undetectable
6cicB-3n3kA:
undetectable		 6cicA-3n3kA:
11.11
6cicB-3n3kA:
11.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CID_A_H4BA802_0
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3n3k UBIQUITIN
CARBOXYL-TERMINAL
HYDROLASE 8
(Homo
sapiens) 		4 / 7 ARG A 944
TRP A1001
PHE A 946
GLU A 908
 None
 1.48A 6cidA-3n3kA:
undetectable
6cidB-3n3kA:
undetectable		 6cidA-3n3kA:
11.11
6cidB-3n3kA:
11.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CID_B_H4BB803_0
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3n3k UBIQUITIN
CARBOXYL-TERMINAL
HYDROLASE 8
(Homo
sapiens) 		4 / 7 TRP A1001
PHE A 946
GLU A 908
ARG A 944
 None
 1.49A 6cidA-3n3kA:
undetectable
6cidB-3n3kA:
undetectable		 6cidA-3n3kA:
11.11
6cidB-3n3kA:
11.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GH9_A_MIXA1003_0
(UBIQUITIN
CARBOXYL-TERMINAL
HYDROLASE 15)		 3n3k UBIQUITIN
CARBOXYL-TERMINAL
HYDROLASE 8
(Homo
sapiens) 		5 / 5 ASN A 781
TYR A1060
GLY A1061
HIS A1067
ASP A1084
 None
 0.38A 6gh9A-3n3kA:
43.1		 6gh9A-3n3kA:
13.35