SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3n6u'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XF1_A_ACTA1107_0
(C5A PEPTIDASE)		 3n6u LYSR TYPE REGULATOR
OF TSAMBCD
(Comamonas
testosteroni) 		4 / 5 GLY A  92
HIS A  93
ILE A  94
PHE A 118
 None
 0.90A 1xf1A-3n6uA:
undetectable		 1xf1A-3n6uA:
11.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XF1_B_ACTB1108_0
(C5A PEPTIDASE)		 3n6u LYSR TYPE REGULATOR
OF TSAMBCD
(Comamonas
testosteroni) 		4 / 6 GLY A  92
HIS A  93
ILE A  94
PHE A 118
 None
 0.90A 1xf1B-3n6uA:
undetectable		 1xf1B-3n6uA:
11.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2I30_A_SALA1200_1
(SERUM ALBUMIN)		 3n6u LYSR TYPE REGULATOR
OF TSAMBCD
(Comamonas
testosteroni) 		4 / 4 LEU A 111
ILE A 291
ILE A 102
ALA A 103
 None
 0.78A 2i30A-3n6uA:
undetectable		 2i30A-3n6uA:
15.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QHF_A_ACTA507_0
(CHORISMATE SYNTHASE)		 3n6u LYSR TYPE REGULATOR
OF TSAMBCD
(Comamonas
testosteroni) 		3 / 3 LEU A 142
ASN A 124
ARG A 126
 None
 0.98A 2qhfA-3n6uA:
undetectable		 2qhfA-3n6uA:
21.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QL8_B_BEZB143_0
(PUTATIVE REDOX
PROTEIN)		 3n6u LYSR TYPE REGULATOR
OF TSAMBCD
(Comamonas
testosteroni) 		4 / 6 TYR A 130
THR A 147
ALA A 145
PRO A 198
 None
None
None
ACT  A1006 (-3.7A)
 1.31A 2ql8A-3n6uA:
undetectable
2ql8B-3n6uA:
undetectable		 2ql8A-3n6uA:
19.91
2ql8B-3n6uA:
19.91
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3FXR_A_ASCA3001_0
(LYSR TYPE REGULATOR
OF TSAMBCD)		 3n6u LYSR TYPE REGULATOR
OF TSAMBCD
(Comamonas
testosteroni) 		6 / 8 HIS A 150
ARG A 199
ALA A 203
ARG A 211
PRO A 266
PRO A 268
 ACT  A1006 ( 3.4A)
None
ACT  A1006 ( 3.8A)
ACT  A1007 (-3.3A)
None
ACT  A1006 (-4.1A)
 1.21A 3fxrA-3n6uA:
22.3		 3fxrA-3n6uA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3FXR_A_ASCA3001_0
(LYSR TYPE REGULATOR
OF TSAMBCD)		 3n6u LYSR TYPE REGULATOR
OF TSAMBCD
(Comamonas
testosteroni) 		6 / 8 HIS A 150
ARG A 199
ALA A 203
ILE A 204
PRO A 266
PRO A 268
 ACT  A1006 ( 3.4A)
None
ACT  A1006 ( 3.8A)
ACT  A1006 ( 4.0A)
None
ACT  A1006 (-4.1A)
 0.94A 3fxrA-3n6uA:
22.3		 3fxrA-3n6uA:
100.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RUN_A_CCSA165_0
(LYSOZYME)		 3n6u LYSR TYPE REGULATOR
OF TSAMBCD
(Comamonas
testosteroni) 		3 / 3 ASN A 250
ALA A 251
LYS A 253
 None
 0.90A 3runA-3n6uA:
undetectable		 3runA-3n6uA:
21.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Y0R_A_PX9A201_0
(BETA-LACTOGLOBULIN)		 3n6u LYSR TYPE REGULATOR
OF TSAMBCD
(Comamonas
testosteroni) 		5 / 12 LEU A 265
ILE A 170
LEU A 239
ILE A 259
PHE A 209
 None
 0.87A 4y0rA-3n6uA:
undetectable		 4y0rA-3n6uA:
19.81