SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3n6x'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DB1_A_VDXA428_2
(VITAMIN D NUCLEAR
RECEPTOR)		 3n6x PUTATIVE
GLUTATHIONYLSPERMIDI
NE SYNTHASE
(Methylobacillus
flagellatus) 		4 / 6 LEU A 163
ILE A 110
TYR A 105
VAL A 326
 None
 1.10A 1db1A-3n6xA:
undetectable		 1db1A-3n6xA:
21.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1E7A_B_PFLB4002_1
(SERUM ALBUMIN)		 3n6x PUTATIVE
GLUTATHIONYLSPERMIDI
NE SYNTHASE
(Methylobacillus
flagellatus) 		4 / 6 LEU A 348
VAL A 357
VAL A 365
GLN A 405
 None
 1.07A 1e7aB-3n6xA:
undetectable		 1e7aB-3n6xA:
21.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UW6_D_NCTD1208_1
(ACETYLCHOLINE-BINDIN
G PROTEIN)		 3n6x PUTATIVE
GLUTATHIONYLSPERMIDI
NE SYNTHASE
(Methylobacillus
flagellatus) 		4 / 8 TYR A 190
CYH A 413
TYR A  23
TRP A 469
 GOL  A 485 (-4.4A)
None
None
None
 1.46A 1uw6D-3n6xA:
undetectable
1uw6E-3n6xA:
undetectable		 1uw6D-3n6xA:
17.58
1uw6E-3n6xA:
17.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UW6_G_NCTG1206_1
(ACETYLCHOLINE-BINDIN
G PROTEIN)		 3n6x PUTATIVE
GLUTATHIONYLSPERMIDI
NE SYNTHASE
(Methylobacillus
flagellatus) 		4 / 8 TYR A 190
CYH A 413
TYR A  23
TRP A 469
 GOL  A 485 (-4.4A)
None
None
None
 1.43A 1uw6G-3n6xA:
undetectable
1uw6H-3n6xA:
undetectable		 1uw6G-3n6xA:
17.58
1uw6H-3n6xA:
17.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UW6_L_NCTL1206_1
(ACETYLCHOLINE-BINDIN
G PROTEIN)		 3n6x PUTATIVE
GLUTATHIONYLSPERMIDI
NE SYNTHASE
(Methylobacillus
flagellatus) 		4 / 7 TYR A 190
CYH A 413
TYR A  23
TRP A 469
 GOL  A 485 (-4.4A)
None
None
None
 1.42A 1uw6L-3n6xA:
0.0
1uw6M-3n6xA:
0.0		 1uw6L-3n6xA:
17.58
1uw6M-3n6xA:
17.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UW6_P_NCTP1206_1
(ACETYLCHOLINE-BINDIN
G PROTEIN)		 3n6x PUTATIVE
GLUTATHIONYLSPERMIDI
NE SYNTHASE
(Methylobacillus
flagellatus) 		4 / 8 TYR A 190
CYH A 413
TYR A  23
TRP A 469
 GOL  A 485 (-4.4A)
None
None
None
 1.39A 1uw6P-3n6xA:
undetectable
1uw6Q-3n6xA:
undetectable		 1uw6P-3n6xA:
17.58
1uw6Q-3n6xA:
17.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2CP4_A_CAMA416_0
(CYTOCHROME P450-CAM)		 3n6x PUTATIVE
GLUTATHIONYLSPERMIDI
NE SYNTHASE
(Methylobacillus
flagellatus) 		5 / 10 THR A 314
THR A 307
VAL A 135
GLY A 138
VAL A 209
 None
 1.36A 2cp4A-3n6xA:
undetectable		 2cp4A-3n6xA:
21.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2RLF_A_RIMA199_1
(MATRIX PROTEIN 2)		 3n6x PUTATIVE
GLUTATHIONYLSPERMIDI
NE SYNTHASE
(Methylobacillus
flagellatus) 		4 / 6 LEU A 297
LEU A 298
ILE A 272
ARG A 274
 None
 1.04A 2rlfA-3n6xA:
undetectable
2rlfB-3n6xA:
undetectable		 2rlfA-3n6xA:
7.22
2rlfB-3n6xA:
7.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BGD_B_PM6B301_1
(THIOPURINE
S-METHYLTRANSFERASE)		 3n6x PUTATIVE
GLUTATHIONYLSPERMIDI
NE SYNTHASE
(Methylobacillus
flagellatus) 		4 / 8 GLY A 145
LEU A 148
PRO A 430
TRP A  83
 None
None
None
GOL  A 488 (-3.9A)
 0.96A 3bgdB-3n6xA:
undetectable		 3bgdB-3n6xA:
20.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LSF_B_PZIB802_0
(GLUTAMATE RECEPTOR 2)		 3n6x PUTATIVE
GLUTATHIONYLSPERMIDI
NE SYNTHASE
(Methylobacillus
flagellatus) 		3 / 3 SER A 349
ASP A 321
ASN A 123
 None
 0.97A 3lsfB-3n6xA:
undetectable
3lsfE-3n6xA:
undetectable		 3lsfB-3n6xA:
19.67
3lsfE-3n6xA:
19.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LSF_E_PZIE802_0
(GLUTAMATE RECEPTOR 2)		 3n6x PUTATIVE
GLUTATHIONYLSPERMIDI
NE SYNTHASE
(Methylobacillus
flagellatus) 		3 / 3 ASP A 321
ASN A 123
SER A 349
 None
 0.93A 3lsfB-3n6xA:
undetectable
3lsfE-3n6xA:
undetectable		 3lsfB-3n6xA:
19.67
3lsfE-3n6xA:
19.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3O01_B_DXCB1_0
(CELL INVASION
PROTEIN SIPD)		 3n6x PUTATIVE
GLUTATHIONYLSPERMIDI
NE SYNTHASE
(Methylobacillus
flagellatus) 		5 / 9 ILE A 143
ALA A 309
LEU A 202
ASN A 205
VAL A 209
 None
 0.92A 3o01A-3n6xA:
undetectable
3o01B-3n6xA:
0.7		 3o01A-3n6xA:
21.54
3o01B-3n6xA:
21.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3O02_B_JN3B1_1
(CELL INVASION
PROTEIN SIPD)		 3n6x PUTATIVE
GLUTATHIONYLSPERMIDI
NE SYNTHASE
(Methylobacillus
flagellatus) 		6 / 10 ILE A 143
ALA A 309
LEU A 202
ASN A 205
LEU A 206
VAL A 209
 None
 0.90A 3o02A-3n6xA:
undetectable
3o02B-3n6xA:
undetectable		 3o02A-3n6xA:
21.54
3o02B-3n6xA:
21.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SPK_B_TPVB100_2
(HIV-1 PROTEASE)		 3n6x PUTATIVE
GLUTATHIONYLSPERMIDI
NE SYNTHASE
(Methylobacillus
flagellatus) 		6 / 12 ARG A  76
LEU A  78
ALA A  84
ILE A  91
GLY A  89
PRO A 430
 None
 1.37A 3spkB-3n6xA:
undetectable		 3spkB-3n6xA:
12.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V4T_E_ACTE502_0
(UDP-N-ACETYLGLUCOSAM
INE
1-CARBOXYVINYLTRANSF
ERASE)		 3n6x PUTATIVE
GLUTATHIONYLSPERMIDI
NE SYNTHASE
(Methylobacillus
flagellatus) 		3 / 3 LYS A 367
ARG A 447
LEU A 159
 None
 1.36A 3v4tE-3n6xA:
undetectable		 3v4tE-3n6xA:
21.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V7P_A_BEZA430_0
(AMIDOHYDROLASE
FAMILY PROTEIN)		 3n6x PUTATIVE
GLUTATHIONYLSPERMIDI
NE SYNTHASE
(Methylobacillus
flagellatus) 		4 / 7 ILE A 470
GLY A 443
PHE A 156
LEU A 428
 None
 0.81A 3v7pA-3n6xA:
undetectable		 3v7pA-3n6xA:
21.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4BBO_C_ACTC1113_0
(BLR5658 PROTEIN)		 3n6x PUTATIVE
GLUTATHIONYLSPERMIDI
NE SYNTHASE
(Methylobacillus
flagellatus) 		4 / 4 ASN A 205
ALA A 208
GLY A 435
THR A 437
 None
GOL  A 495 ( 4.0A)
GOL  A 484 (-4.8A)
None
 1.19A 4bboC-3n6xA:
undetectable		 4bboC-3n6xA:
13.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DXU_A_ACAA711_1
(LACTOTRANSFERRIN)		 3n6x PUTATIVE
GLUTATHIONYLSPERMIDI
NE SYNTHASE
(Methylobacillus
flagellatus) 		4 / 6 GLY A 296
VAL A 253
PRO A 295
GLY A 248
 None
 0.87A 4dxuA-3n6xA:
undetectable		 4dxuA-3n6xA:
21.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UCK_A_SAMA2409_1
(RNA-DIRECTED RNA
POLYMERASE L)		 3n6x PUTATIVE
GLUTATHIONYLSPERMIDI
NE SYNTHASE
(Methylobacillus
flagellatus) 		3 / 3 SER A 349
ASP A 147
ASP A 319
 None
 0.80A 4uckA-3n6xA:
undetectable		 4uckA-3n6xA:
21.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YMG_B_SAMB1001_0
(PUTATIVE
SAM-DEPENDENT
O-METHYLTRANFERASE)		 3n6x PUTATIVE
GLUTATHIONYLSPERMIDI
NE SYNTHASE
(Methylobacillus
flagellatus) 		5 / 12 GLY A 315
TYR A 126
TYR A 140
ALA A 141
ALA A 317
 None
 1.35A 4ymgB-3n6xA:
undetectable		 4ymgB-3n6xA:
19.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KOX_A_RFPA502_2
(PENTACHLOROPHENOL
4-MONOOXYGENASE)		 3n6x PUTATIVE
GLUTATHIONYLSPERMIDI
NE SYNTHASE
(Methylobacillus
flagellatus) 		3 / 3 VAL A  33
ARG A  76
PRO A 414
 None
 0.78A 5koxA-3n6xA:
undetectable		 5koxA-3n6xA:
24.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5SYJ_A_NIZA810_1
(CATALASE-PEROXIDASE)		 3n6x PUTATIVE
GLUTATHIONYLSPERMIDI
NE SYNTHASE
(Methylobacillus
flagellatus) 		4 / 6 ARG A 447
LEU A 450
PRO A  70
SER A 459
 None
None
None
GOL  A 490 ( 3.9A)
 1.46A 5syjA-3n6xA:
undetectable		 5syjA-3n6xA:
23.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5SYJ_B_NIZB810_1
(CATALASE-PEROXIDASE)		 3n6x PUTATIVE
GLUTATHIONYLSPERMIDI
NE SYNTHASE
(Methylobacillus
flagellatus) 		4 / 6 ARG A 447
LEU A 450
PRO A  70
SER A 459
 None
None
None
GOL  A 490 ( 3.9A)
 1.43A 5syjB-3n6xA:
undetectable		 5syjB-3n6xA:
23.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VLM_G_CVIG301_0
(REGULATORY PROTEIN
TETR)		 3n6x PUTATIVE
GLUTATHIONYLSPERMIDI
NE SYNTHASE
(Methylobacillus
flagellatus) 		5 / 12 GLN A 405
ALA A 404
GLU A 160
ILE A 324
ASP A 318
 None
None
GOL  A 491 (-3.3A)
GOL  A 482 (-4.5A)
GOL  A 491 ( 3.3A)
 1.25A 5vlmG-3n6xA:
undetectable		 5vlmG-3n6xA:
16.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XDH_B_DAHB60_1
(PUTATIVE CYTOCHROME
C)		 3n6x PUTATIVE
GLUTATHIONYLSPERMIDI
NE SYNTHASE
(Methylobacillus
flagellatus) 		4 / 5 MET A 260
ASN A 256
VAL A 253
LEU A 251
 None
 1.11A 5xdhB-3n6xA:
undetectable		 5xdhB-3n6xA:
13.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XDH_C_DAHC60_1
(PUTATIVE CYTOCHROME
C)		 3n6x PUTATIVE
GLUTATHIONYLSPERMIDI
NE SYNTHASE
(Methylobacillus
flagellatus) 		4 / 6 MET A 260
ASN A 256
VAL A 253
LEU A 251
 None
 1.30A 5xdhA-3n6xA:
undetectable
5xdhC-3n6xA:
undetectable		 5xdhA-3n6xA:
13.39
5xdhC-3n6xA:
13.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XDH_D_DAHD60_1
(PUTATIVE CYTOCHROME
C)		 3n6x PUTATIVE
GLUTATHIONYLSPERMIDI
NE SYNTHASE
(Methylobacillus
flagellatus) 		4 / 5 MET A 260
ASN A 256
VAL A 253
LEU A 251
 None
 1.20A 5xdhD-3n6xA:
undetectable		 5xdhD-3n6xA:
13.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B50_A_OAQA302_0
(SULFOTRANSFERASE
OXAMNIQUINE
RESISTANCE PROTEIN)		 3n6x PUTATIVE
GLUTATHIONYLSPERMIDI
NE SYNTHASE
(Methylobacillus
flagellatus) 		5 / 12 PRO A 295
ASP A 282
LEU A 284
VAL A 258
VAL A 253
 None
 1.19A 6b50A-3n6xA:
undetectable		 6b50A-3n6xA:
19.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DH0_A_017A101_2
(PROTEASE)		 3n6x PUTATIVE
GLUTATHIONYLSPERMIDI
NE SYNTHASE
(Methylobacillus
flagellatus) 		3 / 3 LEU A 284
ASP A 278
ILE A 276
 None
None
GOL  A 481 (-4.6A)
 0.63A 6dh0B-3n6xA:
undetectable		 6dh0B-3n6xA:
11.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DIL_B_TPVB201_0
(HIV-1 PROTEASE)		 3n6x PUTATIVE
GLUTATHIONYLSPERMIDI
NE SYNTHASE
(Methylobacillus
flagellatus) 		6 / 12 ARG A  76
LEU A  78
ALA A  84
ILE A  91
GLY A  89
PRO A 430
 None
 1.34A 6dilA-3n6xA:
undetectable		 6dilA-3n6xA:
11.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MN5_D_LLLD301_0
(AMINOGLYCOSIDE
N(3)-ACETYLTRANSFERA
SE, AAC(3)-IVA)		 3n6x PUTATIVE
GLUTATHIONYLSPERMIDI
NE SYNTHASE
(Methylobacillus
flagellatus) 		4 / 6 ASP A 277
ARG A 164
ASP A 318
GLU A 160
 GOL  A 496 ( 3.4A)
GOL  A 491 (-4.2A)
GOL  A 491 ( 3.3A)
GOL  A 491 (-3.3A)
 1.35A 6mn5D-3n6xA:
undetectable		 6mn5D-3n6xA:
13.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MN5_E_LLLE301_0
(AMINOGLYCOSIDE
N(3)-ACETYLTRANSFERA
SE, AAC(3)-IVA)		 3n6x PUTATIVE
GLUTATHIONYLSPERMIDI
NE SYNTHASE
(Methylobacillus
flagellatus) 		4 / 7 ASP A 277
ARG A 164
ASP A 318
GLU A 160
 GOL  A 496 ( 3.4A)
GOL  A 491 (-4.2A)
GOL  A 491 ( 3.3A)
GOL  A 491 (-3.3A)
 1.37A 6mn5E-3n6xA:
undetectable		 6mn5E-3n6xA:
13.77