SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3n6z'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1I9G_A_SAMA301_0
(HYPOTHETICAL PROTEIN
RV2118C)		 3n6z PUTATIVE
IMMUNOGLOBULIN A1
PROTEASE
(Bacteroides
ovatus) 		5 / 12 GLY A 164
GLY A 197
ALA A 238
ARG A 162
ASP A 136
 None
None
None
SO4  A   1 (-3.9A)
None
 1.17A 1i9gA-3n6zA:
undetectable		 1i9gA-3n6zA:
23.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JOL_A_FFOA161_0
(DIHYDROFOLATE
REDUCTASE)		 3n6z PUTATIVE
IMMUNOGLOBULIN A1
PROTEASE
(Bacteroides
ovatus) 		5 / 12 ILE A 127
PHE A 140
ILE A 118
LEU A 108
THR A 191
 None
 1.18A 1jolA-3n6zA:
undetectable		 1jolA-3n6zA:
17.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JOL_B_FFOB361_0
(DIHYDROFOLATE
REDUCTASE)		 3n6z PUTATIVE
IMMUNOGLOBULIN A1
PROTEASE
(Bacteroides
ovatus) 		5 / 12 ILE A 127
PHE A 140
ILE A 118
LEU A 108
THR A 191
 None
 1.13A 1jolB-3n6zA:
undetectable		 1jolB-3n6zA:
17.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NV8_B_SAMB301_0
(HEMK PROTEIN)		 3n6z PUTATIVE
IMMUNOGLOBULIN A1
PROTEASE
(Bacteroides
ovatus) 		5 / 12 ILE A 167
GLY A 166
GLY A 206
GLU A 194
PRO A 138
 None
 0.98A 1nv8B-3n6zA:
undetectable		 1nv8B-3n6zA:
23.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SG9_B_SAMB302_0
(HEMK PROTEIN)		 3n6z PUTATIVE
IMMUNOGLOBULIN A1
PROTEASE
(Bacteroides
ovatus) 		5 / 12 ILE A 167
GLY A 166
GLY A 206
GLU A 194
PRO A 138
 None
 0.94A 1sg9B-3n6zA:
undetectable		 1sg9B-3n6zA:
22.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SGU_B_MK1B2632_2
(POL POLYPROTEIN)		 3n6z PUTATIVE
IMMUNOGLOBULIN A1
PROTEASE
(Bacteroides
ovatus) 		5 / 12 GLY A 243
ALA A 242
ILE A 186
GLY A 170
ILE A 165
 None
 1.03A 1sguB-3n6zA:
undetectable		 1sguB-3n6zA:
13.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SV9_A_DIFA701_1
(PHOSPHOLIPASE A2)		 3n6z PUTATIVE
IMMUNOGLOBULIN A1
PROTEASE
(Bacteroides
ovatus) 		4 / 8 ILE A  97
GLY A 122
CYH A 148
PHE A 141
 None
 0.58A 1sv9A-3n6zA:
undetectable		 1sv9A-3n6zA:
16.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TNL_A_TPAA900_1
(TRYPSIN)		 3n6z PUTATIVE
IMMUNOGLOBULIN A1
PROTEASE
(Bacteroides
ovatus) 		4 / 6 SER A 290
SER A 224
GLY A 239
GLY A 270
 None
 0.73A 1tnlA-3n6zA:
undetectable		 1tnlA-3n6zA:
22.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1VQ1_B_SAMB301_0
(N5-GLUTAMINE
METHYLTRANSFERASE,
HEMK)		 3n6z PUTATIVE
IMMUNOGLOBULIN A1
PROTEASE
(Bacteroides
ovatus) 		5 / 12 ILE A 167
GLY A 166
GLY A 206
GLU A 194
PRO A 138
 None
 0.89A 1vq1B-3n6zA:
undetectable		 1vq1B-3n6zA:
22.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NYU_A_SAMA201_0
(PUTATIVE RIBOSOMAL
RNA
METHYLTRANSFERASE 2)		 3n6z PUTATIVE
IMMUNOGLOBULIN A1
PROTEASE
(Bacteroides
ovatus) 		5 / 12 SER A 224
ALA A 205
GLY A 202
LEU A 144
LEU A 172
 None
 1.03A 2nyuA-3n6zA:
undetectable		 2nyuA-3n6zA:
20.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NYU_B_SAMB201_0
(PUTATIVE RIBOSOMAL
RNA
METHYLTRANSFERASE 2)		 3n6z PUTATIVE
IMMUNOGLOBULIN A1
PROTEASE
(Bacteroides
ovatus) 		5 / 12 SER A 224
ALA A 205
GLY A 202
LEU A 144
LEU A 172
 None
 0.99A 2nyuB-3n6zA:
undetectable		 2nyuB-3n6zA:
20.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OTV_A_NCAA1301_0
(CATIONIC TRYPSIN)		 3n6z PUTATIVE
IMMUNOGLOBULIN A1
PROTEASE
(Bacteroides
ovatus) 		4 / 6 SER A 290
SER A 224
GLY A 239
GLY A 270
 None
 0.78A 2otvA-3n6zA:
undetectable		 2otvA-3n6zA:
22.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QHF_A_ACTA502_0
(CHORISMATE SYNTHASE)		 3n6z PUTATIVE
IMMUNOGLOBULIN A1
PROTEASE
(Bacteroides
ovatus) 		3 / 3 GLY A 135
ASP A 136
SER A 107
 None
 0.67A 2qhfA-3n6zA:
undetectable		 2qhfA-3n6zA:
22.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VIN_A_505A1247_1
(UROKINASE-TYPE
PLASMINOGEN
ACTIVATOR CHAIN B)		 3n6z PUTATIVE
IMMUNOGLOBULIN A1
PROTEASE
(Bacteroides
ovatus) 		4 / 8 SER A 290
SER A 224
GLY A 239
GLY A 270
 None
 0.72A 2vinA-3n6zA:
undetectable		 2vinA-3n6zA:
19.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YY8_B_SAMB500_0
(UPF0106 PROTEIN
PH0461)		 3n6z PUTATIVE
IMMUNOGLOBULIN A1
PROTEASE
(Bacteroides
ovatus) 		5 / 11 HIS A 346
LEU A 272
GLY A 270
VAL A 261
ILE A 275
 None
 1.07A 2yy8A-3n6zA:
undetectable
2yy8B-3n6zA:
undetectable		 2yy8A-3n6zA:
16.62
2yy8B-3n6zA:
16.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZW9_B_SAMB801_0
(LEUCINE CARBOXYL
METHYLTRANSFERASE 2)		 3n6z PUTATIVE
IMMUNOGLOBULIN A1
PROTEASE
(Bacteroides
ovatus) 		5 / 12 GLY A 240
GLY A 203
LEU A 292
ASN A 291
TYR A 258
 None
 1.16A 2zw9B-3n6zA:
undetectable		 2zw9B-3n6zA:
18.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_D_DVAD47_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		 3n6z PUTATIVE
IMMUNOGLOBULIN A1
PROTEASE
(Bacteroides
ovatus) 		4 / 4 GLY A 239
GLY A 273
GLY A 267
GLY A 269
 None
 0.68A 3bogD-3n6zA:
undetectable		 3bogD-3n6zA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BRF_A_SORA1_0
(LIN-12 AND GLP-1
PHENOTYPE PROTEIN 1,
ISOFORM A)		 3n6z PUTATIVE
IMMUNOGLOBULIN A1
PROTEASE
(Bacteroides
ovatus) 		3 / 3 GLY A 235
ASP A 230
SER A 198
 None
None
GOL  A   5 (-3.5A)
 0.70A 3brfA-3n6zA:
undetectable		 3brfA-3n6zA:
23.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EKQ_A_ROCA100_1
(PROTEASE)		 3n6z PUTATIVE
IMMUNOGLOBULIN A1
PROTEASE
(Bacteroides
ovatus) 		6 / 12 GLY A 193
ALA A 156
ILE A 127
VAL A 126
GLY A 152
ILE A 167
 None
 1.33A 3ekqA-3n6zA:
undetectable		 3ekqA-3n6zA:
13.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EM0_B_CHDB153_0
(ILEAL BILE
ACID-BINDING PROTEIN)		 3n6z PUTATIVE
IMMUNOGLOBULIN A1
PROTEASE
(Bacteroides
ovatus) 		4 / 7 ILE A 204
PHE A 120
PHE A 140
GLY A 206
 None
 1.11A 3em0B-3n6zA:
undetectable		 3em0B-3n6zA:
18.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JWQ_D_VIAD901_1
(CGMP-SPECIFIC
3',5'-CYCLIC
PHOSPHODIESTERASE
CATALYTIC DOMAIN,
CONE CGMP-SPECIFIC
3',5'-CYCLIC
PHOSPHODIESTERASE
SUBUNIT ALPHA
CHIMERA)		 3n6z PUTATIVE
IMMUNOGLOBULIN A1
PROTEASE
(Bacteroides
ovatus) 		5 / 11 ARG A 149
LEU A  93
ALA A 156
PHE A 141
LEU A 172
 None
 1.39A 3jwqA-3n6zA:
undetectable
3jwqD-3n6zA:
undetectable		 3jwqA-3n6zA:
19.43
3jwqD-3n6zA:
19.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEE_B_30BB500_1
(GENOME POLYPROTEIN)		 3n6z PUTATIVE
IMMUNOGLOBULIN A1
PROTEASE
(Bacteroides
ovatus) 		5 / 12 VAL A 228
GLY A 269
ARG A 244
ALA A 200
ALA A 201
 None
None
SO4  A   2 (-2.8A)
None
None
 1.09A 3keeB-3n6zA:
undetectable		 3keeB-3n6zA:
18.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEE_C_30BC500_1
(GENOME POLYPROTEIN)		 3n6z PUTATIVE
IMMUNOGLOBULIN A1
PROTEASE
(Bacteroides
ovatus) 		5 / 12 VAL A 228
GLY A 269
ARG A 244
ALA A 200
ALA A 201
 None
None
SO4  A   2 (-2.8A)
None
None
 1.07A 3keeC-3n6zA:
undetectable		 3keeC-3n6zA:
18.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_G_TFPG201_1
(PROTEIN S100-A4)		 3n6z PUTATIVE
IMMUNOGLOBULIN A1
PROTEASE
(Bacteroides
ovatus) 		5 / 9 GLY A 250
PHE A 251
GLY A 173
ILE A 204
CYH A 222
 None
 1.20A 3ko0F-3n6zA:
undetectable
3ko0G-3n6zA:
undetectable		 3ko0F-3n6zA:
15.10
3ko0G-3n6zA:
15.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_K_TFPK201_1
(PROTEIN S100-A4)		 3n6z PUTATIVE
IMMUNOGLOBULIN A1
PROTEASE
(Bacteroides
ovatus) 		4 / 8 GLY A 173
ILE A 204
CYH A 222
PHE A 251
 None
 1.02A 3ko0K-3n6zA:
undetectable
3ko0S-3n6zA:
undetectable		 3ko0K-3n6zA:
15.10
3ko0S-3n6zA:
15.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3O7W_A_SAMA801_0
(LEUCINE CARBOXYL
METHYLTRANSFERASE 1)		 3n6z PUTATIVE
IMMUNOGLOBULIN A1
PROTEASE
(Bacteroides
ovatus) 		5 / 12 ALA A 156
GLY A 202
GLY A 166
ILE A 165
VAL A 228
 None
 1.03A 3o7wA-3n6zA:
undetectable		 3o7wA-3n6zA:
21.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QL0_A_FOLA160_0
(DIHYDROFOLATE
REDUCTASE)		 3n6z PUTATIVE
IMMUNOGLOBULIN A1
PROTEASE
(Bacteroides
ovatus) 		5 / 12 ILE A 127
PHE A 140
ILE A 118
LEU A 108
THR A 191
 None
 1.20A 3ql0A-3n6zA:
undetectable		 3ql0A-3n6zA:
18.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V7P_A_BEZA430_0
(AMIDOHYDROLASE
FAMILY PROTEIN)		 3n6z PUTATIVE
IMMUNOGLOBULIN A1
PROTEASE
(Bacteroides
ovatus) 		4 / 7 ILE A 165
GLY A 166
SER A 139
PHE A 130
 None
 0.77A 3v7pA-3n6zA:
undetectable		 3v7pA-3n6zA:
23.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L8F_B_MTXB301_1
(GAMMA-GLUTAMYL
HYDROLASE)		 3n6z PUTATIVE
IMMUNOGLOBULIN A1
PROTEASE
(Bacteroides
ovatus) 		5 / 11 GLY A 202
GLY A 166
GLY A 170
ALA A 201
GLN A 163
 None
 1.13A 4l8fB-3n6zA:
undetectable		 4l8fB-3n6zA:
22.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LG1_B_SAMB301_0
(PROTEIN-LYSINE
METHYLTRANSFERASE
METTL21D)		 3n6z PUTATIVE
IMMUNOGLOBULIN A1
PROTEASE
(Bacteroides
ovatus) 		5 / 12 ALA A 319
GLY A 269
GLY A 302
LYS A 237
ALA A 288
 None
 1.15A 4lg1B-3n6zA:
undetectable		 4lg1B-3n6zA:
21.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XNX_A_41XA707_1
(TRANSPORTER)		 3n6z PUTATIVE
IMMUNOGLOBULIN A1
PROTEASE
(Bacteroides
ovatus) 		5 / 11 ALA A 242
VAL A 207
TYR A 171
GLY A 236
GLY A 202
 None
None
GOL  A   4 (-3.7A)
None
None
 1.13A 4xnxA-3n6zA:
undetectable		 4xnxA-3n6zA:
20.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AQF_C_ADNC1382_1
(HEAT SHOCK COGNATE
71 KDA PROTEIN)		 3n6z PUTATIVE
IMMUNOGLOBULIN A1
PROTEASE
(Bacteroides
ovatus) 		5 / 10 GLY A 240
GLY A 270
GLY A 259
SER A 290
ILE A 323
 None
 0.92A 5aqfC-3n6zA:
undetectable		 5aqfC-3n6zA:
22.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AQY_A_ADNA1389_1
(HEAT SHOCK 70 KDA
PROTEIN 1A)		 3n6z PUTATIVE
IMMUNOGLOBULIN A1
PROTEASE
(Bacteroides
ovatus) 		5 / 10 GLY A 240
GLY A 270
GLY A 259
SER A 290
ILE A 323
 None
 0.93A 5aqyA-3n6zA:
undetectable		 5aqyA-3n6zA:
22.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FHR_A_SAMA303_1
(CATECHOL
O-METHYLTRANSFERASE)		 3n6z PUTATIVE
IMMUNOGLOBULIN A1
PROTEASE
(Bacteroides
ovatus) 		4 / 5 SER A 107
TYR A 171
SER A 198
ASP A 136
 None
GOL  A   4 (-3.7A)
GOL  A   5 (-3.5A)
None
 1.44A 5fhrA-3n6zA:
undetectable		 5fhrA-3n6zA:
20.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5GQB_A_GCSA605_1
(CHITINASE)		 3n6z PUTATIVE
IMMUNOGLOBULIN A1
PROTEASE
(Bacteroides
ovatus) 		3 / 3 TRP A 367
ILE A 376
SER A 380
 None
 0.99A 5gqbA-3n6zA:
undetectable		 5gqbA-3n6zA:
21.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HW8_B_FK5B201_1
(FK506-BINDING
PROTEIN 1)		 3n6z PUTATIVE
IMMUNOGLOBULIN A1
PROTEASE
(Bacteroides
ovatus) 		5 / 11 VAL A 126
ILE A 168
ILE A 186
ILE A 204
PHE A 377
 None
 1.22A 5hw8B-3n6zA:
undetectable		 5hw8B-3n6zA:
16.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N8J_E_DVAE7_0
(GLY-DTY-GLY-DLE-DAL-
DSG-DVA-DAS-DGL-DSN-
DSN-GLY
STREPTAVIDIN)		 3n6z PUTATIVE
IMMUNOGLOBULIN A1
PROTEASE
(Bacteroides
ovatus) 		3 / 3 TYR A 256
SER A 224
TRP A 367
 None
 0.86A 5n8jB-3n6zA:
undetectable		 5n8jB-3n6zA:
20.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N8J_O_DVAO7_0
(GLY-DTY-GLY-DLE-DAL-
DSG-DVA-DAS-DGL-DSN-
DSN-GLY
STREPTAVIDIN)		 3n6z PUTATIVE
IMMUNOGLOBULIN A1
PROTEASE
(Bacteroides
ovatus) 		3 / 3 TYR A 256
SER A 224
TRP A 367
 None
 0.93A 5n8jA-3n6zA:
undetectable		 5n8jA-3n6zA:
20.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N8J_P_DVAP5_0
(GLY-DTY-GLY-DLE-DAL-
DSG-DVA-DAS-DGL-DSN-
DSN-GLY
STREPTAVIDIN)		 3n6z PUTATIVE
IMMUNOGLOBULIN A1
PROTEASE
(Bacteroides
ovatus) 		3 / 3 TYR A 256
SER A 224
TRP A 367
 None
 0.97A 5n8jD-3n6zA:
undetectable		 5n8jD-3n6zA:
20.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WM2_A_ACTA605_0
(SALICYLATE-AMP
LIGASE)		 3n6z PUTATIVE
IMMUNOGLOBULIN A1
PROTEASE
(Bacteroides
ovatus) 		3 / 3 THR A  32
THR A  74
ARG A  77
 None
 1.04A 5wm2A-3n6zA:
undetectable		 5wm2A-3n6zA:
21.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WYQ_A_SAMA401_0
(TRNA
(GUANINE-N(1)-)-METH
YLTRANSFERASE)		 3n6z PUTATIVE
IMMUNOGLOBULIN A1
PROTEASE
(Bacteroides
ovatus) 		5 / 12 LEU A 208
GLY A 206
GLY A 164
ILE A 281
GLY A 243
 None
 1.06A 5wyqA-3n6zA:
undetectable		 5wyqA-3n6zA:
20.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Y9Y_A_ACTA409_0
(UNCHARACTERIZED
PROTEIN KDOO)		 3n6z PUTATIVE
IMMUNOGLOBULIN A1
PROTEASE
(Bacteroides
ovatus) 		3 / 3 LYS A  66
PRO A  67
LYS A  59
 None
 1.29A 5y9yA-3n6zA:
undetectable		 5y9yA-3n6zA:
21.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AG0_A_ACRA606_0
(ALPHA-AMYLASE)		 3n6z PUTATIVE
IMMUNOGLOBULIN A1
PROTEASE
(Bacteroides
ovatus) 		5 / 7 GLY A 269
GLY A 270
GLY A 240
GLY A 203
GLY A 202
 None
 1.09A 6ag0A-3n6zA:
undetectable		 6ag0A-3n6zA:
13.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CLX_A_SAMA401_0
(O-METHYLTRANSFERASE)		 3n6z PUTATIVE
IMMUNOGLOBULIN A1
PROTEASE
(Bacteroides
ovatus) 		5 / 12 ALA A 263
GLY A 270
GLY A 239
SER A 286
VAL A 301
 None
 1.31A 6clxA-3n6zA:
undetectable		 6clxA-3n6zA:
22.95