SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3n77'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1D4F_B_ADNB602_1
(S-ADENOSYLHOMOCYSTEI
NE HYDROLASE)		 3n77 NUCLEOSIDE
TRIPHOSPHATASE NUDI
(Salmonella
enterica) 		5 / 12 LEU A  58
GLU A 110
LEU A  50
GLY A  38
PHE A 111
 None
 1.11A 1d4fB-3n77A:
undetectable		 1d4fB-3n77A:
15.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1D4F_C_ADNC603_1
(S-ADENOSYLHOMOCYSTEI
NE HYDROLASE)		 3n77 NUCLEOSIDE
TRIPHOSPHATASE NUDI
(Salmonella
enterica) 		5 / 12 LEU A  58
GLU A 110
LEU A  50
GLY A  38
PHE A 111
 None
 1.08A 1d4fC-3n77A:
undetectable		 1d4fC-3n77A:
15.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RXC_C_URFC2081_1
(URIDINE
PHOSPHORYLASE)		 3n77 NUCLEOSIDE
TRIPHOSPHATASE NUDI
(Salmonella
enterica) 		4 / 7 GLY A  37
ARG A  52
ILE A   6
VAL A   7
 None
 1.00A 1rxcC-3n77A:
undetectable		 1rxcC-3n77A:
18.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FU9_A_ACTA312_0
(UROKINASE-TYPE
PLASMINOGEN
ACTIVATOR)		 3n77 NUCLEOSIDE
TRIPHOSPHATASE NUDI
(Salmonella
enterica) 		3 / 3 ARG A  73
HIS A 133
TYR A  93
 None
 0.93A 4fu9A-3n77A:
undetectable		 4fu9A-3n77A:
20.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZME_A_ADNA1002_1
(MYOSIN HEAVY CHAIN
KINASE A)		 3n77 NUCLEOSIDE
TRIPHOSPHATASE NUDI
(Salmonella
enterica) 		5 / 11 PHE A 111
GLY A  38
LEU A 127
LEU A  19
THR A 131
 None
 1.16A 4zmeA-3n77A:
undetectable		 4zmeA-3n77A:
16.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IGY_A_ERYA403_1
(MACROLIDE
2'-PHOSPHOTRANSFERAS
E II)		 3n77 NUCLEOSIDE
TRIPHOSPHATASE NUDI
(Salmonella
enterica) 		4 / 6 ILE A  95
ARG A  73
TYR A  93
TYR A  90
 None
 1.45A 5igyA-3n77A:
undetectable		 5igyA-3n77A:
19.40