SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3n79'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1T46_A_STIA3_2
(HOMO SAPIENS V-KIT
HARDY-ZUCKERMAN 4
FELINE SARCOMA VIRAL
ONCOGENE HOMOLOG)		 3n79 PDUT
(Salmonella
enterica) 		4 / 7 VAL A 140
VAL A  81
ARG A 167
CYH A 136
 None
 1.26A 1t46A-3n79A:
undetectable		 1t46A-3n79A:
21.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V95_A_HCYA1375_1
(CORTICOSTEROID-BINDI
NG GLOBULIN)		 3n79 PDUT
(Salmonella
enterica) 		5 / 12 ALA A  84
PRO A  83
THR A 102
ILE A 109
ASP A 113
 None
 1.31A 2v95A-3n79A:
undetectable		 2v95A-3n79A:
20.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KP6_A_SALA3005_1
(TRANSCRIPTIONAL
REGULATOR TCAR)		 3n79 PDUT
(Salmonella
enterica) 		4 / 8 ASN A 149
ALA A 154
SER A 155
ARG A 167
 None
 0.94A 3kp6A-3n79A:
undetectable		 3kp6A-3n79A:
20.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KOU_A_C04A207_1
(UNCHARACTERIZED
PROTEIN)		 3n79 PDUT
(Salmonella
enterica) 		3 / 3 GLY A 134
GLU A 101
THR A 102
 None
 0.50A 4kouA-3n79A:
undetectable		 4kouA-3n79A:
23.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L39_B_SALB601_1
(4-SUBSTITUTED
BENZOATES-GLUTAMATE
LIGASE GH3.12)		 3n79 PDUT
(Salmonella
enterica) 		4 / 7 LEU A  10
THR A  61
ILE A  57
GLY A  20
 None
 0.95A 4l39B-3n79A:
undetectable		 4l39B-3n79A:
15.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LG1_A_SAMA301_0
(PROTEIN-LYSINE
METHYLTRANSFERASE
METTL21D)		 3n79 PDUT
(Salmonella
enterica) 		6 / 12 ALA A  27
GLY A   6
GLY A  47
LEU A  32
ALA A  56
GLU A   9
 None
 1.43A 4lg1A-3n79A:
undetectable		 4lg1A-3n79A:
21.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LG1_B_SAMB301_0
(PROTEIN-LYSINE
METHYLTRANSFERASE
METTL21D)		 3n79 PDUT
(Salmonella
enterica) 		6 / 12 ALA A  27
GLY A   6
GLY A  47
LEU A  32
ALA A  56
GLU A   9
 None
 1.43A 4lg1B-3n79A:
undetectable		 4lg1B-3n79A:
21.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RTM_A_SAMA301_0
(DNA ADENINE
METHYLASE)		 3n79 PDUT
(Salmonella
enterica) 		5 / 12 GLY A 134
GLY A 133
ILE A  99
SER A 168
TYR A 166
 None
 1.01A 4rtmA-3n79A:
undetectable		 4rtmA-3n79A:
20.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HRQ_E_IPHE101_0
(INSULIN A-CHAIN
INSULIN B-CHAIN)		 3n79 PDUT
(Salmonella
enterica) 		5 / 7 ILE A 109
CYH A 108
HIS A  78
LEU A 123
ALA A 115
 None
 1.31A 5hrqE-3n79A:
undetectable
5hrqF-3n79A:
undetectable
5hrqJ-3n79A:
undetectable		 5hrqE-3n79A:
6.42
5hrqF-3n79A:
7.81
5hrqJ-3n79A:
7.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IGI_A_ZITA402_1
(MACROLIDE
2'-PHOSPHOTRANSFERAS
E)		 3n79 PDUT
(Salmonella
enterica) 		5 / 12 ILE A 109
ASP A  70
VAL A  33
GLY A  60
THR A  61
 None
 1.23A 5igiA-3n79A:
undetectable		 5igiA-3n79A:
23.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5O96_G_SAMG501_0
(RIBOSOMAL RNA SMALL
SUBUNIT
METHYLTRANSFERASE E)		 3n79 PDUT
(Salmonella
enterica) 		5 / 11 GLY A 133
GLY A 131
SER A  71
LEU A  72
ALA A 106
 None
 0.97A 5o96G-3n79A:
undetectable		 5o96G-3n79A:
22.64