SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3n7p'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LK0_D_Z80D92_1
(PROTEIN S100-B)		 3n7p RECEPTOR
ACTIVITY-MODIFYING
PROTEIN 1
(Homo
sapiens) 		3 / 3 HIS D  75
PHE D  92
PHE D  93
 None
 0.74A 3lk0D-3n7pD:
undetectable		 3lk0D-3n7pD:
19.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UPW_A_NCAA412_0
(OLD YELLOW ENZYME
2.6 (OYE2.6), NADPH
DEHYDROGENASE)		 3n7p CALCITONIN
GENE-RELATED PEPTIDE
TYPE 1 RECEPTOR
RECEPTOR
ACTIVITY-MODIFYING
PROTEIN 1
(Homo
sapiens;
Homo
sapiens) 		5 / 9 THR D  73
ALA D  70
TYR A  49
ASN D  86
TYR D  32
 None
SO4  D  11 (-4.0A)
None
SO4  A  16 (-4.8A)
None
 1.43A 3upwA-3n7pD:
undetectable		 3upwA-3n7pD:
13.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M5M_A_DX4A401_0
(2-AMINO-4-HYDROXY-6-
HYDROXYMETHYLDIHYDRO
PTERIDINE
PYROPHOSPHOKINASE)		 3n7p RECEPTOR
ACTIVITY-MODIFYING
PROTEIN 1
(Homo
sapiens) 		4 / 8 GLY D  33
THR D  73
LEU D  41
PHE D  92
 None
 1.12A 4m5mA-3n7pD:
undetectable		 4m5mA-3n7pD:
21.60