SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3n7x'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1WRL_C_TFPC208_1
(TROPONIN C, SLOW
SKELETAL AND CARDIAC
MUSCLES)		 3n7x CAPSID PROTEIN
(Decapod
penstyldensoviru
s
1) 		4 / 5 PHE A  56
LEU A  81
PHE A  58
MET A 266
 None
 1.23A 1wrlC-3n7xA:
undetectable		 1wrlC-3n7xA:
14.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QMZ_B_LDPB502_1
(RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE)		 3n7x CAPSID PROTEIN
(Decapod
penstyldensoviru
s
1) 		4 / 5 GLN A 263
PHE A 265
PHE A 197
GLY A 157
 None
 1.42A 2qmzA-3n7xA:
undetectable
2qmzB-3n7xA:
undetectable		 2qmzA-3n7xA:
21.41
2qmzB-3n7xA:
21.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A9J_B_TYLB1187_1
(BROMODOMAIN
CONTAINING 2)		 3n7x CAPSID PROTEIN
(Decapod
penstyldensoviru
s
1) 		4 / 5 VAL A 113
LEU A 293
LEU A 291
ILE A 225
 None
 0.92A 4a9jB-3n7xA:
undetectable		 4a9jB-3n7xA:
16.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FIM_A_CELA711_1
(LACTOTRANSFERRIN)		 3n7x CAPSID PROTEIN
(Decapod
penstyldensoviru
s
1) 		5 / 9 GLY A  43
PRO A 245
TYR A 311
GLY A 110
TYR A 109
 None
 1.45A 4fimA-3n7xA:
undetectable		 4fimA-3n7xA:
20.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QZT_A_RTLA201_1
(RETINOL-BINDING
PROTEIN 2)		 3n7x CAPSID PROTEIN
(Decapod
penstyldensoviru
s
1) 		3 / 3 PHE A  58
THR A  52
LEU A  74
 None
 0.70A 4qztA-3n7xA:
undetectable		 4qztA-3n7xA:
16.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N0X_B_SAMB501_1
(PEPTIDE
N-METHYLTRANSFERASE)		 3n7x CAPSID PROTEIN
(Decapod
penstyldensoviru
s
1) 		3 / 3 SER A  92
ALA A  93
THR A 227
 None
 0.55A 5n0xB-3n7xA:
undetectable		 5n0xB-3n7xA:
21.92