SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3n7z'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DHI_A_MTXA161_1
(DIHYDROFOLATE
REDUCTASE)		 3n7z ACETYLTRANSFERASE,
GNAT FAMILY
(Bacillus
anthracis) 		5 / 12 ILE A 343
ALA A 345
LEU A 307
LEU A 291
ILE A 284
 None
 1.01A 1dhiA-3n7zA:
undetectable		 1dhiA-3n7zA:
17.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DHI_B_MTXB361_1
(DIHYDROFOLATE
REDUCTASE)		 3n7z ACETYLTRANSFERASE,
GNAT FAMILY
(Bacillus
anthracis) 		5 / 11 ILE A 343
ALA A 345
LEU A 307
LEU A 291
ILE A 284
 None
 1.03A 1dhiB-3n7zA:
undetectable		 1dhiB-3n7zA:
17.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DHJ_B_MTXB361_1
(DIHYDROFOLATE
REDUCTASE)		 3n7z ACETYLTRANSFERASE,
GNAT FAMILY
(Bacillus
anthracis) 		5 / 12 ILE A 343
ALA A 345
LEU A 307
LEU A 291
ILE A 284
 None
 0.99A 1dhjB-3n7zA:
undetectable		 1dhjB-3n7zA:
17.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DRA_A_MTXA161_1
(DIHYDROFOLATE
REDUCTASE)		 3n7z ACETYLTRANSFERASE,
GNAT FAMILY
(Bacillus
anthracis) 		5 / 12 ILE A 343
ALA A 345
LEU A 307
LEU A 291
ILE A 284
 None
 1.01A 1draA-3n7zA:
undetectable		 1draA-3n7zA:
17.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DRA_B_MTXB361_1
(DIHYDROFOLATE
REDUCTASE)		 3n7z ACETYLTRANSFERASE,
GNAT FAMILY
(Bacillus
anthracis) 		5 / 12 ILE A 343
ALA A 345
LEU A 307
LEU A 291
ILE A 284
 None
 1.03A 1draB-3n7zA:
undetectable		 1draB-3n7zA:
17.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RA3_A_MTXA161_1
(DIHYDROFOLATE
REDUCTASE)		 3n7z ACETYLTRANSFERASE,
GNAT FAMILY
(Bacillus
anthracis) 		5 / 12 ILE A 343
ALA A 345
LEU A 307
LEU A 291
ILE A 284
 None
 1.01A 1ra3A-3n7zA:
undetectable		 1ra3A-3n7zA:
17.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RB2_B_FOLB161_0
(DIHYDROFOLATE
REDUCTASE)		 3n7z ACETYLTRANSFERASE,
GNAT FAMILY
(Bacillus
anthracis) 		5 / 12 ILE A 343
ALA A 345
LEU A 307
LEU A 291
ILE A 284
 None
 1.14A 1rb2B-3n7zA:
undetectable		 1rb2B-3n7zA:
17.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RX7_A_FOLA161_0
(DIHYDROFOLATE
REDUCTASE)		 3n7z ACETYLTRANSFERASE,
GNAT FAMILY
(Bacillus
anthracis) 		5 / 12 ILE A 343
ALA A 345
LEU A 307
LEU A 291
ILE A 284
 None
 0.96A 1rx7A-3n7zA:
undetectable		 1rx7A-3n7zA:
17.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZLQ_A_ACTA1507_0
(NICKEL-BINDING
PERIPLASMIC PROTEIN)		 3n7z ACETYLTRANSFERASE,
GNAT FAMILY
(Bacillus
anthracis) 		3 / 3 GLN A 245
HIS A 246
ARG A 158
 None
 1.09A 1zlqA-3n7zA:
undetectable		 1zlqA-3n7zA:
21.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DRC_A_MTXA161_1
(DIHYDROFOLATE
REDUCTASE)		 3n7z ACETYLTRANSFERASE,
GNAT FAMILY
(Bacillus
anthracis) 		5 / 12 ILE A 343
ALA A 345
LEU A 307
LEU A 291
ILE A 284
 None
 1.02A 2drcA-3n7zA:
undetectable		 2drcA-3n7zA:
17.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DRC_B_MTXB161_1
(DIHYDROFOLATE
REDUCTASE)		 3n7z ACETYLTRANSFERASE,
GNAT FAMILY
(Bacillus
anthracis) 		5 / 12 ILE A 343
ALA A 345
LEU A 307
LEU A 291
ILE A 284
 None
 1.00A 2drcB-3n7zA:
undetectable		 2drcB-3n7zA:
17.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QHF_A_ACTA508_0
(CHORISMATE SYNTHASE)		 3n7z ACETYLTRANSFERASE,
GNAT FAMILY
(Bacillus
anthracis) 		4 / 5 LEU A  20
ARG A  17
ALA A  19
ILE A  40
 None
 1.14A 2qhfA-3n7zA:
undetectable		 2qhfA-3n7zA:
22.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QQD_B_AG2B671_1
(PYRUVOYL-DEPENDENT
ARGININE
DECARBOXYLASE (EC
4.1.1.19) (PVLARGDC))		 3n7z ACETYLTRANSFERASE,
GNAT FAMILY
(Bacillus
anthracis) 		4 / 8 ILE A 349
ARG A 355
LEU A 296
GLY A 352
 None
 0.92A 2qqdB-3n7zA:
undetectable
2qqdC-3n7zA:
undetectable		 2qqdB-3n7zA:
17.17
2qqdC-3n7zA:
16.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W98_A_P1ZA1352_1
(PROSTAGLANDIN
REDUCTASE 2)		 3n7z ACETYLTRANSFERASE,
GNAT FAMILY
(Bacillus
anthracis) 		4 / 7 TYR A  25
LEU A  22
LYS A  61
TYR A  29
 None
 1.36A 2w98A-3n7zA:
undetectable
2w98B-3n7zA:
undetectable		 2w98A-3n7zA:
21.91
2w98B-3n7zA:
21.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZZN_B_SAMB402_0
(UNCHARACTERIZED
PROTEIN MJ0883)		 3n7z ACETYLTRANSFERASE,
GNAT FAMILY
(Bacillus
anthracis) 		5 / 12 TYR A 353
ARG A 126
PHE A 280
GLY A 282
ILE A  69
 None
 1.17A 2zznB-3n7zA:
undetectable		 2zznB-3n7zA:
23.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ARU_A_PNXA606_1
(CHITINASE A)		 3n7z ACETYLTRANSFERASE,
GNAT FAMILY
(Bacillus
anthracis) 		4 / 7 PHE A 280
GLY A  80
ASP A 388
ARG A 185
 None
 1.24A 3aruA-3n7zA:
undetectable		 3aruA-3n7zA:
21.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DRC_A_MTXA161_1
(DIHYDROFOLATE
REDUCTASE)		 3n7z ACETYLTRANSFERASE,
GNAT FAMILY
(Bacillus
anthracis) 		5 / 12 ILE A 343
ALA A 345
LEU A 307
LEU A 291
ILE A 284
 None
 1.02A 3drcA-3n7zA:
undetectable		 3drcA-3n7zA:
17.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DRC_B_MTXB361_1
(DIHYDROFOLATE
REDUCTASE)		 3n7z ACETYLTRANSFERASE,
GNAT FAMILY
(Bacillus
anthracis) 		5 / 12 ILE A 343
ALA A 345
LEU A 307
LEU A 291
ILE A 284
 None
 1.02A 3drcB-3n7zA:
undetectable		 3drcB-3n7zA:
17.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HGX_A_SALA102_1
(SALICYLATE
BIOSYNTHESIS PROTEIN
PCHB)		 3n7z ACETYLTRANSFERASE,
GNAT FAMILY
(Bacillus
anthracis) 		4 / 7 MET A 116
ILE A  69
TYR A  70
ILE A  71
 None
 0.78A 3hgxA-3n7zA:
undetectable		 3hgxA-3n7zA:
12.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LOQ_A_ACTA278_0
(UNIVERSAL STRESS
PROTEIN)		 3n7z ACETYLTRANSFERASE,
GNAT FAMILY
(Bacillus
anthracis) 		3 / 3 SER A 115
GLY A  80
SER A 103
 None
 0.58A 3loqA-3n7zA:
undetectable		 3loqA-3n7zA:
22.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TQ9_A_MTXA2001_1
(DIHYDROFOLATE
REDUCTASE)		 3n7z ACETYLTRANSFERASE,
GNAT FAMILY
(Bacillus
anthracis) 		5 / 12 ILE A 343
ALA A 345
LEU A 307
LEU A 291
ILE A 284
 None
 0.91A 3tq9A-3n7zA:
undetectable		 3tq9A-3n7zA:
17.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C8B_B_0LIB1000_2
(RECEPTOR-INTERACTING
SERINE/THREONINE-PRO
TEIN KINASE 2)		 3n7z ACETYLTRANSFERASE,
GNAT FAMILY
(Bacillus
anthracis) 		3 / 3 TYR A 213
MET A 214
ILE A 218
 None
 0.87A 4c8bB-3n7zA:
undetectable		 4c8bB-3n7zA:
21.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DFR_B_MTXB162_1
(DIHYDROFOLATE
REDUCTASE)		 3n7z ACETYLTRANSFERASE,
GNAT FAMILY
(Bacillus
anthracis) 		5 / 12 ILE A 343
ALA A 345
LEU A 307
LEU A 291
ILE A 284
 None
 0.99A 4dfrB-3n7zA:
undetectable		 4dfrB-3n7zA:
17.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KIC_B_SAMB401_1
(METHYLTRANSFERASE
MPPJ)		 3n7z ACETYLTRANSFERASE,
GNAT FAMILY
(Bacillus
anthracis) 		3 / 3 ARG A 271
ASP A 145
ASP A 252
 None
 0.84A 4kicB-3n7zA:
undetectable		 4kicB-3n7zA:
21.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4P3R_A_FOLA201_0
(DIHYDROFOLATE
REDUCTASE)		 3n7z ACETYLTRANSFERASE,
GNAT FAMILY
(Bacillus
anthracis) 		5 / 12 ILE A 343
ALA A 345
LEU A 307
LEU A 291
ILE A 284
 None
 1.04A 4p3rA-3n7zA:
undetectable		 4p3rA-3n7zA:
17.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4P66_A_MTXA201_1
(DIHYDROFOLATE
REDUCTASE)		 3n7z ACETYLTRANSFERASE,
GNAT FAMILY
(Bacillus
anthracis) 		5 / 11 ILE A 343
ALA A 345
LEU A 307
LEU A 291
ILE A 284
 None
 1.03A 4p66A-3n7zA:
undetectable		 4p66A-3n7zA:
17.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MUG_A_VIVA301_0
(ALPHA-TOCOPHEROL
TRANSFER PROTEIN)		 3n7z ACETYLTRANSFERASE,
GNAT FAMILY
(Bacillus
anthracis) 		5 / 12 ILE A 328
ILE A 372
ILE A 309
LEU A 341
ILE A 349
 None
 1.08A 5mugA-3n7zA:
undetectable		 5mugA-3n7zA:
23.08