SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3n89'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PNJ_B_CHDB501_0
(FERROCHELATASE,
MITOCHONDRIAL)		 3n89 DEFECTIVE IN GERM
LINE DEVELOPMENT
PROTEIN 3, ISOFORM A
(Caenorhabditis
elegans) 		5 / 12 LEU A 448
LEU A 443
ILE A 345
SER A 442
VAL A 296
 None
 1.35A 2pnjB-3n89A:
undetectable		 2pnjB-3n89A:
21.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q83_B_ADNB2_1
(YTAA PROTEIN)		 3n89 DEFECTIVE IN GERM
LINE DEVELOPMENT
PROTEIN 3, ISOFORM A
(Caenorhabditis
elegans) 		4 / 6 ILE A 170
PRO A 431
LEU A 412
ILE A 409
 None
 1.02A 2q83B-3n89A:
undetectable		 2q83B-3n89A:
21.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Z0A_A_GLYA73_0
(NONSTRUCTURAL
PROTEIN 1)		 3n89 DEFECTIVE IN GERM
LINE DEVELOPMENT
PROTEIN 3, ISOFORM A
(Caenorhabditis
elegans) 		4 / 5 GLN A 417
ALA A 428
GLN A 430
ILE A 427
 None
 1.50A 2z0aA-3n89A:
undetectable		 2z0aA-3n89A:
10.64