SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3n93'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LHV_A_NOGA301_1
(SEX HORMONE-BINDING
GLOBULIN)		 3n93 MALTOSE BINDING
PROTEIN-CRFR2 ALPHA
(Homo
sapiens) 		4 / 8 SER A-115
THR A-145
ASN A-220
LEU A-123
 None
 1.00A 1lhvA-3n93A:
undetectable		 1lhvA-3n93A:
16.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AOH_C_FRDC305_2
(POL POLYPROTEIN
PEPTIDE INHIBITOR)		 3n93 MALTOSE BINDING
PROTEIN-CRFR2 ALPHA
(Homo
sapiens) 		4 / 5 LEU A-108
GLY A -81
ALA A-261
ILE A-262
 None
 0.82A 2aohB-3n93A:
undetectable		 2aohB-3n93A:
13.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BFP_C_H4BC1290_1
(PTERIDINE REDUCTASE
1)		 3n93 MALTOSE BINDING
PROTEIN-CRFR2 ALPHA
(Homo
sapiens) 		4 / 8 ASP A  45
TYR A  95
LEU A  10
LEU A   6
 None
 0.98A 2bfpC-3n93A:
undetectable		 2bfpC-3n93A:
22.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BFP_D_H4BD1290_1
(PTERIDINE REDUCTASE
1)		 3n93 MALTOSE BINDING
PROTEIN-CRFR2 ALPHA
(Homo
sapiens) 		4 / 8 ASP A  45
TYR A  95
LEU A  10
LEU A   6
 None
 1.00A 2bfpD-3n93A:
undetectable		 2bfpD-3n93A:
22.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2H42_A_VIAA901_1
(CGMP-SPECIFIC
3',5'-CYCLIC
PHOSPHODIESTERASE)		 3n93 MALTOSE BINDING
PROTEIN-CRFR2 ALPHA
(Homo
sapiens) 		5 / 11 ALA A -67
ILE A-262
VAL A-273
LEU A-294
ILE A-291
 None
 1.26A 2h42A-3n93A:
undetectable		 2h42A-3n93A:
19.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2H42_C_VIAC903_1
(CGMP-SPECIFIC
3',5'-CYCLIC
PHOSPHODIESTERASE)		 3n93 MALTOSE BINDING
PROTEIN-CRFR2 ALPHA
(Homo
sapiens) 		5 / 12 LEU A-108
ILE A-262
VAL A-273
LEU A-294
ILE A-291
 None
 0.95A 2h42C-3n93A:
undetectable		 2h42C-3n93A:
19.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BGD_A_PM6A301_1
(THIOPURINE
S-METHYLTRANSFERASE)		 3n93 MALTOSE BINDING
PROTEIN-CRFR2 ALPHA
(Homo
sapiens) 		4 / 6 PHE A-112
ALA A-208
LEU A-123
PRO A-211
 None
 0.96A 3bgdA-3n93A:
undetectable		 3bgdA-3n93A:
19.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BJW_C_SVRC507_1
(PHOSPHOLIPASE A2)		 3n93 MALTOSE BINDING
PROTEIN-CRFR2 ALPHA
(Homo
sapiens) 		4 / 7 VAL A-260
GLY A -70
PRO A-141
LYS A -65
 None
 0.73A 3bjwC-3n93A:
undetectable		 3bjwC-3n93A:
13.38
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3JYR_A_ACRA371_1
(MALTOSE-BINDING
PERIPLASMIC PROTEIN)		 3n93 MALTOSE BINDING
PROTEIN-CRFR2 ALPHA
(Homo
sapiens) 		9 / 12 ASP A-356
LYS A-355
LYS A-328
GLU A-326
GLU A-325
ALA A-307
ASP A-305
ARG A-304
GLU A-259
 MAL  A 111 (-3.1A)
MAL  A 111 (-2.7A)
None
None
None
MAL  A 111 (-3.3A)
MAL  A 111 (-2.8A)
MAL  A 111 (-3.6A)
MAL  A 111 (-3.4A)
 0.73A 3jyrA-3n93A:
61.9		 3jyrA-3n93A:
68.97
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3JYR_A_ACRA371_1
(MALTOSE-BINDING
PERIPLASMIC PROTEIN)		 3n93 MALTOSE BINDING
PROTEIN-CRFR2 ALPHA
(Homo
sapiens) 		10 / 12 ASP A-356
LYS A-355
LYS A-328
GLU A-326
GLU A-325
ALA A-307
ASP A-305
GLU A-259
PRO A-216
TRP A-140
 MAL  A 111 (-3.1A)
MAL  A 111 (-2.7A)
None
None
None
MAL  A 111 (-3.3A)
MAL  A 111 (-2.8A)
MAL  A 111 (-3.4A)
MAL  A 111 (-3.5A)
MAL  A 111 ( 4.6A)
 0.44A 3jyrA-3n93A:
61.9		 3jyrA-3n93A:
68.97
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3JYR_A_ACRA371_2
(MALTOSE-BINDING
PERIPLASMIC PROTEIN)		 3n93 MALTOSE BINDING
PROTEIN-CRFR2 ALPHA
(Homo
sapiens) 		6 / 7 ASN A-358
TRP A-308
GLU A-217
TYR A-215
MET A -40
TRP A -30
 MAL  A 111 (-4.4A)
MAL  A 111 (-4.4A)
MAL  A 111 (-3.7A)
MAL  A 111 (-3.9A)
MAL  A 111 ( 4.4A)
MAL  A 111 (-3.6A)
 0.24A 3jyrA-3n93A:
61.9		 3jyrA-3n93A:
68.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N8Y_B_DIFB585_1
(PROSTAGLANDIN G/H
SYNTHASE 1)		 3n93 MALTOSE BINDING
PROTEIN-CRFR2 ALPHA
(Homo
sapiens) 		5 / 12 VAL A-174
LEU A-210
GLY A-183
ALA A-182
LEU A  -9
 None
 0.97A 3n8yB-3n93A:
undetectable		 3n8yB-3n93A:
20.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SJ4_X_DXCX75_0
(CYTOCHROME C7)		 3n93 MALTOSE BINDING
PROTEIN-CRFR2 ALPHA
(Homo
sapiens) 		5 / 9 ILE A-238
LEU A-172
LYS A-114
ILE A-144
GLY A-179
 None
 1.22A 3sj4X-3n93A:
undetectable		 3sj4X-3n93A:
9.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TBG_B_RTZB1_1
(CYTOCHROME P450 2D6)		 3n93 MALTOSE BINDING
PROTEIN-CRFR2 ALPHA
(Homo
sapiens) 		5 / 12 PHE A-214
GLY A -70
LEU A -71
GLU A-259
ALA A-139
 None
None
None
MAL  A 111 (-3.4A)
None
 0.86A 3tbgB-3n93A:
undetectable		 3tbgB-3n93A:
21.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TBG_D_RTZD1_1
(CYTOCHROME P450 2D6)		 3n93 MALTOSE BINDING
PROTEIN-CRFR2 ALPHA
(Homo
sapiens) 		5 / 12 PHE A-214
GLY A -70
LEU A -71
GLU A-259
ALA A-139
 None
None
None
MAL  A 111 (-3.4A)
None
 0.84A 3tbgD-3n93A:
undetectable		 3tbgD-3n93A:
21.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VWQ_A_ACAA601_1
(6-AMINOHEXANOATE-DIM
ER HYDROLASE)		 3n93 MALTOSE BINDING
PROTEIN-CRFR2 ALPHA
(Homo
sapiens) 		5 / 12 ALA A-139
TYR A-353
TYR A-160
ASN A-136
GLY A-142
 None
 1.39A 3vwqA-3n93A:
undetectable		 3vwqA-3n93A:
21.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VWR_A_ACAA601_1
(6-AMINOHEXANOATE-DIM
ER HYDROLASE)		 3n93 MALTOSE BINDING
PROTEIN-CRFR2 ALPHA
(Homo
sapiens) 		5 / 11 ALA A-139
ASP A -74
TYR A-160
ASN A-136
GLY A-142
 None
 1.30A 3vwrA-3n93A:
undetectable		 3vwrA-3n93A:
21.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VYW_A_SAMA501_1
(MNMC2)		 3n93 MALTOSE BINDING
PROTEIN-CRFR2 ALPHA
(Homo
sapiens) 		4 / 6 GLU A -62
ASP A -56
ASP A -83
ASN A -76
 None
 1.33A 3vywA-3n93A:
undetectable		 3vywA-3n93A:
20.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VYW_D_SAMD401_1
(MNMC2)		 3n93 MALTOSE BINDING
PROTEIN-CRFR2 ALPHA
(Homo
sapiens) 		4 / 5 GLU A -62
ASP A -56
ASP A -83
ASN A -76
 None
 1.31A 3vywD-3n93A:
undetectable		 3vywD-3n93A:
20.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A7T_F_5FWF1001_1
(SUPEROXIDE DISMUTASE
[CU-ZN])		 3n93 MALTOSE BINDING
PROTEIN-CRFR2 ALPHA
(Homo
sapiens) 		4 / 6 GLU A-367
LYS A-369
PRO A -99
GLU A-366
 None
 1.36A 4a7tF-3n93A:
undetectable		 4a7tF-3n93A:
16.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M2X_G_TMQG202_1
(DIHYDROFOLATE
REDUCTASE)		 3n93 MALTOSE BINDING
PROTEIN-CRFR2 ALPHA
(Homo
sapiens) 		5 / 12 ILE A-104
ALA A-265
LEU A-350
VAL A-347
ILE A-311
 None
 1.11A 4m2xG-3n93A:
undetectable		 4m2xG-3n93A:
17.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4N48_A_SAMA601_1
(CAP-SPECIFIC MRNA
(NUCLEOSIDE-2'-O-)-M
ETHYLTRANSFERASE 1)		 3n93 MALTOSE BINDING
PROTEIN-CRFR2 ALPHA
(Homo
sapiens) 		4 / 5 ASN A-103
ALA A-319
GLY A-314
ASP A-356
 None
None
None
MAL  A 111 (-3.1A)
 0.98A 4n48A-3n93A:
undetectable		 4n48A-3n93A:
20.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OR0_B_NPSB602_1
(SERUM ALBUMIN)		 3n93 MALTOSE BINDING
PROTEIN-CRFR2 ALPHA
(Homo
sapiens) 		5 / 9 ALA A-106
ALA A-265
LEU A-267
LEU A-108
VAL A-109
 None
 1.16A 4or0B-3n93A:
undetectable		 4or0B-3n93A:
22.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4P65_E_IPHE101_0
(INSULIN)		 3n93 MALTOSE BINDING
PROTEIN-CRFR2 ALPHA
(Homo
sapiens) 		5 / 11 ILE A-238
LEU A-231
LEU A-248
ALA A-147
LEU A-255
 None
 1.08A 4p65E-3n93A:
undetectable
4p65F-3n93A:
undetectable
4p65J-3n93A:
undetectable
4p65L-3n93A:
undetectable		 4p65E-3n93A:
3.95
4p65F-3n93A:
5.70
4p65J-3n93A:
5.70
4p65L-3n93A:
5.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4P65_K_IPHK101_0
(INSULIN)		 3n93 MALTOSE BINDING
PROTEIN-CRFR2 ALPHA
(Homo
sapiens) 		5 / 12 LEU A-255
ILE A-238
LEU A-231
LEU A-248
ALA A-147
 None
 1.04A 4p65F-3n93A:
undetectable
4p65H-3n93A:
undetectable
4p65K-3n93A:
undetectable
4p65L-3n93A:
undetectable		 4p65F-3n93A:
5.70
4p65H-3n93A:
5.70
4p65K-3n93A:
3.95
4p65L-3n93A:
5.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5W4Z_A_RBFA502_1
(RIBOFLAVIN LYASE)		 3n93 MALTOSE BINDING
PROTEIN-CRFR2 ALPHA
(Homo
sapiens) 		6 / 12 ALA A -28
ALA A -32
GLY A-204
ALA A-182
PHE A-201
VAL A-189
 None
 1.40A 5w4zA-3n93A:
undetectable		 5w4zA-3n93A:
8.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5W4Z_B_RBFB502_1
(RIBOFLAVIN LYASE)		 3n93 MALTOSE BINDING
PROTEIN-CRFR2 ALPHA
(Homo
sapiens) 		6 / 12 ALA A -28
ALA A -32
GLY A-204
ALA A-182
PHE A-201
VAL A-189
 None
 1.43A 5w4zB-3n93A:
undetectable		 5w4zB-3n93A:
8.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B58_A_ACTA603_0
(FUMARATE REDUCTASE
FLAVOPROTEIN SUBUNIT)		 3n93 MALTOSE BINDING
PROTEIN-CRFR2 ALPHA
(Homo
sapiens) 		3 / 3 TYR A-215
ASN A-143
LEU A-257
 MAL  A 111 (-3.9A)
None
None
 0.82A 6b58A-3n93A:
undetectable		 6b58A-3n93A:
22.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6ECX_A_SAMA1301_0
(STIE PROTEIN)		 3n93 MALTOSE BINDING
PROTEIN-CRFR2 ALPHA
(Homo
sapiens) 		5 / 12 LEU A -95
GLY A-346
VAL A-335
LEU A-363
ILE A-361
 None
 0.98A 6ecxA-3n93A:
undetectable		 6ecxA-3n93A:
20.87