SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3n9b'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1NT2_A_SAMA301_1 (FIBRILLARIN-LIKE PRE-RRNA PROCESSING PROTEIN)	3n9b	PROBABLE ATP-DEPENDENT DNA LIGASE (Pseudomonas aeruginosa)	3 / 3	THR A 114 GLU A 54 ASP A 87	None	0.72A	1nt2A-3n9bA: undetectable	1nt2A-3n9bA: 22.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1NW3_A_SAMA500_0 (HISTONE METHYLTRANSFERASE DOT1L)	3n9b	PROBABLE ATP-DEPENDENT DNA LIGASE (Pseudomonas aeruginosa)	5 / 12	GLU A 135 ALA A 112 PHE A 130 LEU A 128 PHE A 51	YT3 A 190 ( 2.2A) None None None None	1.26A	1nw3A-3n9bA: undetectable	1nw3A-3n9bA: 18.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3QOW_A_SAMA417_0 (HISTONE-LYSINE N-METHYLTRANSFERASE)	3n9b	PROBABLE ATP-DEPENDENT DNA LIGASE (Pseudomonas aeruginosa)	5 / 12	TYR A 37 GLY A 111 VAL A 107 LYS A 60 ASP A 83	None	1.24A	3qowA-3n9bA: undetectable	3qowA-3n9bA: 18.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4JTR_A_IBPA401_1 (ALDO-KETO REDUCTASE FAMILY 1 MEMBER C2)	3n9b	PROBABLE ATP-DEPENDENT DNA LIGASE (Pseudomonas aeruginosa)	4 / 8	VAL A 39 TRP A 141 LEU A 143 LEU A 157	None	1.06A	4jtrA-3n9bA: undetectable	4jtrA-3n9bA: 20.43

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["1NT2_A_SAMA301_1","FIBRILLARIN-LIKE PRE-RRNA PROCESSING PROTEIN","3n9b","PROBABLE ATP-DEPENDENT DNA LIGASE","Pseudomonas aeruginosa",3,"THR A 114;GLU A  54;ASP A  87","None","0.72A","1nt2A-3n9bA:undetectable","1nt2A-3n9bA:22.64"],["1NW3_A_SAMA500_0","HISTONE METHYLTRANSFERASE DOT1L","3n9b","PROBABLE ATP-DEPENDENT DNA LIGASE","Pseudomonas aeruginosa",5,"GLU A 135;ALA A 112;PHE A 130;LEU A 128;PHE A  51","YT3 A 190 ( 2.2A);None;None;None;None","1.26A","1nw3A-3n9bA:undetectable","1nw3A-3n9bA:18.63"],["3QOW_A_SAMA417_0","HISTONE-LYSINE N-METHYLTRANSFERASE","3n9b","PROBABLE ATP-DEPENDENT DNA LIGASE","Pseudomonas aeruginosa",5,"TYR A  37;GLY A 111;VAL A 107;LYS A  60;ASP A  83","None","1.24A","3qowA-3n9bA:undetectable","3qowA-3n9bA:18.63"],["4JTR_A_IBPA401_1","ALDO-KETO REDUCTASE FAMILY 1 MEMBER C2","3n9b","PROBABLE ATP-DEPENDENT DNA LIGASE","Pseudomonas aeruginosa",4,"VAL A  39;TRP A 141;LEU A 143;LEU A 157","None","1.06A","4jtrA-3n9bA:undetectable","4jtrA-3n9bA:20.43"]]