SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3n9o'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1G50_A_ESTA600_1
(ESTROGEN RECEPTOR)		 3n9o PUTATIVE
UNCHARACTERIZED
PROTEIN
(Caenorhabditis
elegans) 		6 / 11 LEU A 425
LEU A 484
ALA A 485
LEU A 576
MET A 382
ILE A 381
 None
 1.44A 1g50A-3n9oA:
undetectable		 1g50A-3n9oA:
17.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GSE_A_EAAA224_1
(GLUTATHIONE
TRANSFERASE)		 3n9o PUTATIVE
UNCHARACTERIZED
PROTEIN
(Caenorhabditis
elegans) 		5 / 12 TYR A 504
GLY A 579
LEU A 484
ALA A 437
PHE A 427
 None
 1.24A 1gseA-3n9oA:
2.7		 1gseA-3n9oA:
19.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1PK2_A_ACAA91_1
(TISSUE-TYPE
PLASMINOGEN
ACTIVATOR)		 3n9o PUTATIVE
UNCHARACTERIZED
PROTEIN
(Caenorhabditis
elegans) 		4 / 8 TYR A 595
TRP A 663
HIS A 620
LEU A 619
 None
 1.21A 1pk2A-3n9oA:
undetectable		 1pk2A-3n9oA:
10.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2E5D_A_NCAA1501_0
(NICOTINAMIDE
PHOSPHORIBOSYLTRANSF
ERASE)		 3n9o PUTATIVE
UNCHARACTERIZED
PROTEIN
(Caenorhabditis
elegans) 		4 / 7 ASP A 335
ARG A 340
ASP A 362
TYR A 337
 None
 1.22A 2e5dA-3n9oA:
undetectable
2e5dB-3n9oA:
undetectable		 2e5dA-3n9oA:
21.00
2e5dB-3n9oA:
21.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2E5D_B_NCAB1502_0
(NICOTINAMIDE
PHOSPHORIBOSYLTRANSF
ERASE)		 3n9o PUTATIVE
UNCHARACTERIZED
PROTEIN
(Caenorhabditis
elegans) 		4 / 7 ASP A 362
TYR A 337
ASP A 335
ARG A 340
 None
 1.19A 2e5dA-3n9oA:
undetectable
2e5dB-3n9oA:
undetectable		 2e5dA-3n9oA:
21.00
2e5dB-3n9oA:
21.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2UVN_B_ECNB1406_1
(CYTOCHROME P450 130)		 3n9o PUTATIVE
UNCHARACTERIZED
PROTEIN
(Caenorhabditis
elegans) 		5 / 11 PRO A 440
PRO A 439
MET A 361
GLY A 579
LEU A 560
 None
 1.42A 2uvnB-3n9oA:
2.4		 2uvnB-3n9oA:
20.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2UVN_B_ECNB1406_1
(CYTOCHROME P450 130)		 3n9o PUTATIVE
UNCHARACTERIZED
PROTEIN
(Caenorhabditis
elegans) 		5 / 11 PRO A 440
PRO A 439
MET A 361
GLY A 580
LEU A 560
 None
 1.48A 2uvnB-3n9oA:
2.4		 2uvnB-3n9oA:
20.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VCT_A_ASDA1223_1
(GLUTATHIONE
S-TRANSFERASE A2)		 3n9o PUTATIVE
UNCHARACTERIZED
PROTEIN
(Caenorhabditis
elegans) 		4 / 8 GLY A 579
LEU A 484
LEU A 423
PHE A 498
 None
None
OGA  A   4 (-4.4A)
None
 0.73A 2vctA-3n9oA:
3.5		 2vctA-3n9oA:
18.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VCT_B_ASDB1223_1
(GLUTATHIONE
S-TRANSFERASE A2)		 3n9o PUTATIVE
UNCHARACTERIZED
PROTEIN
(Caenorhabditis
elegans) 		4 / 8 GLY A 579
LEU A 484
LEU A 423
PHE A 498
 None
None
OGA  A   4 (-4.4A)
None
 0.75A 2vctB-3n9oA:
5.0		 2vctB-3n9oA:
18.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VJ1_A_BEZA1303_0
(SARS CORONAVIRUS
MAIN PROTEINASE)		 3n9o PUTATIVE
UNCHARACTERIZED
PROTEIN
(Caenorhabditis
elegans) 		3 / 3 HIS A 506
MET A 368
MET A 361
 None
 1.33A 2vj1A-3n9oA:
undetectable		 2vj1A-3n9oA:
18.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VJ1_A_BEZA1303_0
(SARS CORONAVIRUS
MAIN PROTEINASE)		 3n9o PUTATIVE
UNCHARACTERIZED
PROTEIN
(Caenorhabditis
elegans) 		3 / 3 HIS A 620
MET A 660
MET A 592
 None
 1.31A 2vj1A-3n9oA:
undetectable		 2vj1A-3n9oA:
18.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZS9_A_PAUA603_0
(PANTOTHENATE KINASE)		 3n9o PUTATIVE
UNCHARACTERIZED
PROTEIN
(Caenorhabditis
elegans) 		4 / 6 ASP A 497
HIS A 567
TYR A 505
ASN A 421
 FE2  A   1 ( 2.6A)
FE2  A   1 ( 3.3A)
OGA  A   4 (-4.1A)
OGA  A   4 (-4.0A)
 1.16A 2zs9A-3n9oA:
undetectable		 2zs9A-3n9oA:
19.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3COT_A_STRA1501_1
(3-OXO-5-BETA-STEROID
4-DEHYDROGENASE)		 3n9o PUTATIVE
UNCHARACTERIZED
PROTEIN
(Caenorhabditis
elegans) 		4 / 7 TYR A 264
GLU A 262
TYR A 420
TRP A 294
 None
 1.34A 3cotA-3n9oA:
undetectable		 3cotA-3n9oA:
20.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DH0_A_SAMA220_1
(SAM DEPENDENT
METHYLTRANSFERASE)		 3n9o PUTATIVE
UNCHARACTERIZED
PROTEIN
(Caenorhabditis
elegans) 		4 / 8 TYR A 623
GLN A 697
GLU A 638
GLU A 646
 None
 1.33A 3dh0A-3n9oA:
undetectable		 3dh0A-3n9oA:
18.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KCX_A_CQLA1_0
(HYPOXIA-INDUCIBLE
FACTOR 1-ALPHA
INHIBITOR)		 3n9o PUTATIVE
UNCHARACTERIZED
PROTEIN
(Caenorhabditis
elegans) 		5 / 10 LEU A 484
HIS A 495
ASP A 497
ILE A 561
HIS A 567
 None
FE2  A   1 ( 3.3A)
FE2  A   1 ( 2.6A)
None
FE2  A   1 ( 3.3A)
 0.89A 3kcxA-3n9oA:
16.3		 3kcxA-3n9oA:
20.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KCX_A_CQLA1_0
(HYPOXIA-INDUCIBLE
FACTOR 1-ALPHA
INHIBITOR)		 3n9o PUTATIVE
UNCHARACTERIZED
PROTEIN
(Caenorhabditis
elegans) 		6 / 10 LEU A 484
THR A 492
HIS A 495
ASP A 497
LYS A 512
HIS A 567
 None
OGA  A   4 (-3.7A)
FE2  A   1 ( 3.3A)
FE2  A   1 ( 2.6A)
OGA  A   4 (-3.5A)
FE2  A   1 ( 3.3A)
 0.89A 3kcxA-3n9oA:
16.3		 3kcxA-3n9oA:
20.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LP9_D_SPMD230_1
(LS-24)		 3n9o PUTATIVE
UNCHARACTERIZED
PROTEIN
(Caenorhabditis
elegans) 		3 / 3 GLU A 617
GLU A 598
ASN A 599
 None
 0.77A 3lp9B-3n9oA:
undetectable
3lp9D-3n9oA:
undetectable		 3lp9B-3n9oA:
17.88
3lp9D-3n9oA:
17.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OCT_A_1N1A663_2
(TYROSINE-PROTEIN
KINASE BTK)		 3n9o PUTATIVE
UNCHARACTERIZED
PROTEIN
(Caenorhabditis
elegans) 		4 / 5 PHE A 494
ILE A 561
ASN A 545
PHE A 514
 None
 1.26A 3octA-3n9oA:
undetectable		 3octA-3n9oA:
19.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3R6W_A_NFZA213_1
(FMN-DEPENDENT
NADH-AZOREDUCTASE 1)		 3n9o PUTATIVE
UNCHARACTERIZED
PROTEIN
(Caenorhabditis
elegans) 		5 / 10 PHE A 356
GLY A 353
PHE A 582
PHE A 442
PHE A 339
 None
 1.32A 3r6wA-3n9oA:
undetectable
3r6wB-3n9oA:
undetectable		 3r6wA-3n9oA:
18.62
3r6wB-3n9oA:
18.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3R6W_A_NFZA214_1
(FMN-DEPENDENT
NADH-AZOREDUCTASE 1)		 3n9o PUTATIVE
UNCHARACTERIZED
PROTEIN
(Caenorhabditis
elegans) 		5 / 10 PHE A 582
PHE A 442
PHE A 339
PHE A 356
GLY A 353
 None
 1.33A 3r6wA-3n9oA:
undetectable
3r6wB-3n9oA:
undetectable		 3r6wA-3n9oA:
18.62
3r6wB-3n9oA:
18.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RV5_A_DXCA91_0
(TROPONIN C, SLOW
SKELETAL AND CARDIAC
MUSCLES)		 3n9o PUTATIVE
UNCHARACTERIZED
PROTEIN
(Caenorhabditis
elegans) 		3 / 3 PHE A 578
GLN A 444
PHE A 373
 None
 0.80A 3rv5A-3n9oA:
undetectable		 3rv5A-3n9oA:
10.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SMT_A_ACTA1001_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE
SETD3)		 3n9o PUTATIVE
UNCHARACTERIZED
PROTEIN
(Caenorhabditis
elegans) 		4 / 5 LEU A 346
GLY A 347
PHE A 343
PHE A 356
 None
 1.08A 3smtA-3n9oA:
undetectable		 3smtA-3n9oA:
23.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WEO_A_ACRA1001_2
(ALPHA-GLUCOSIDASE)		 3n9o PUTATIVE
UNCHARACTERIZED
PROTEIN
(Caenorhabditis
elegans) 		4 / 6 ILE A 688
TRP A 650
ILE A 649
MET A 624
 None
 1.49A 3weoA-3n9oA:
undetectable		 3weoA-3n9oA:
18.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4P7N_A_GCSA702_1
(POLY-BETA-1,6-N-ACET
YL-D-GLUCOSAMINE
N-DEACETYLASE)		 3n9o PUTATIVE
UNCHARACTERIZED
PROTEIN
(Caenorhabditis
elegans) 		3 / 3 ASP A 392
TYR A 420
TRP A 294
 None
 1.36A 4p7nA-3n9oA:
undetectable		 4p7nA-3n9oA:
22.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5A1R_A_STRA600_1
(CYTOCHROME P450 3A4)		 3n9o PUTATIVE
UNCHARACTERIZED
PROTEIN
(Caenorhabditis
elegans) 		4 / 5 PHE A 613
ASP A 497
PHE A 498
VAL A 479
 None
FE2  A   1 ( 2.6A)
None
None
 1.19A 5a1rA-3n9oA:
undetectable		 5a1rA-3n9oA:
22.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEI_B_SHHB801_1
(HDAC6 PROTEIN)		 3n9o PUTATIVE
UNCHARACTERIZED
PROTEIN
(Caenorhabditis
elegans) 		6 / 12 PRO A 477
SER A 501
GLY A 499
PHE A 613
HIS A 620
LEU A 619
 None
 1.50A 5eeiB-3n9oA:
undetectable		 5eeiB-3n9oA:
20.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N4T_A_BEZA507_0
(BETA-LACTAMASE VIM-2)		 3n9o PUTATIVE
UNCHARACTERIZED
PROTEIN
(Caenorhabditis
elegans) 		3 / 3 THR A 205
HIS A 252
ASN A 237
 None
ZN  A   2 (-3.2A)
None
 0.99A 5n4tA-3n9oA:
undetectable		 5n4tA-3n9oA:
18.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ND4_B_TA1B601_1
(TUBULIN BETA-2B
CHAIN)		 3n9o PUTATIVE
UNCHARACTERIZED
PROTEIN
(Caenorhabditis
elegans) 		5 / 12 ASP A 374
LEU A 484
ALA A 485
PHE A 422
LEU A 403
 None
 1.23A 5nd4B-3n9oA:
undetectable		 5nd4B-3n9oA:
20.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OV9_B_CVIB603_0
(ACETYLCHOLINESTERASE)		 3n9o PUTATIVE
UNCHARACTERIZED
PROTEIN
(Caenorhabditis
elegans) 		4 / 7 TYR A 515
GLN A 396
TRP A 539
HIS A 530
 None
 1.38A 5ov9B-3n9oA:
undetectable		 5ov9B-3n9oA:
20.24