SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3n9t'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FE2_A_LAXA700_2
(PROSTAGLANDIN
ENDOPEROXIDE H
SYNTHASE-1)		 3n9t PNPC
(Pseudomonas
putida) 		5 / 12 TYR A 259
PHE A 221
GLY A 134
GLY A 271
LEU A 272
 None
 1.13A 1fe2A-3n9tA:
undetectable		 1fe2A-3n9tA:
18.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1IE4_B_T44B328_1
(TRANSTHYRETIN)		 3n9t PNPC
(Pseudomonas
putida) 		4 / 8 LEU A 219
LYS A 279
ALA A 130
THR A 188
 None
 0.94A 1ie4B-3n9tA:
2.4
1ie4D-3n9tA:
2.4		 1ie4B-3n9tA:
24.21
1ie4D-3n9tA:
24.21
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1S9A_A_BEZA306_0
(CHLOROCATECHOL
1,2-DIOXYGENASE)		 3n9t PNPC
(Pseudomonas
putida) 		7 / 11 GLY A 106
PRO A 107
TYR A 160
TYR A 194
ARG A 215
HIS A 218
HIS A 220
 FLC  A 293 ( 4.3A)
FLC  A 293 (-3.5A)
FE  A 292 ( 4.3A)
FLC  A 293 ( 4.0A)
FLC  A 293 (-4.3A)
FE  A 292 ( 3.2A)
FE  A 292 ( 3.1A)
 0.36A 1s9aA-3n9tA:
28.2		 1s9aA-3n9tA:
31.56
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1S9A_A_BEZA306_0
(CHLOROCATECHOL
1,2-DIOXYGENASE)		 3n9t PNPC
(Pseudomonas
putida) 		5 / 11 GLY A 106
TYR A 194
ARG A 215
HIS A 218
HIS A 234
 FLC  A 293 ( 4.3A)
FLC  A 293 ( 4.0A)
FLC  A 293 (-4.3A)
FE  A 292 ( 3.2A)
None
 1.45A 1s9aA-3n9tA:
28.2		 1s9aA-3n9tA:
31.56
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1S9A_B_BEZB307_0
(CHLOROCATECHOL
1,2-DIOXYGENASE)		 3n9t PNPC
(Pseudomonas
putida) 		5 / 12 GLY A 106
PRO A 107
ARG A 215
HIS A 218
HIS A 234
 FLC  A 293 ( 4.3A)
FLC  A 293 (-3.5A)
FLC  A 293 (-4.3A)
FE  A 292 ( 3.2A)
None
 1.42A 1s9aB-3n9tA:
28.0		 1s9aB-3n9tA:
31.56
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1S9A_B_BEZB307_0
(CHLOROCATECHOL
1,2-DIOXYGENASE)		 3n9t PNPC
(Pseudomonas
putida) 		7 / 12 GLY A 106
PRO A 107
TYR A 160
TYR A 194
ARG A 215
HIS A 218
HIS A 220
 FLC  A 293 ( 4.3A)
FLC  A 293 (-3.5A)
FE  A 292 ( 4.3A)
FLC  A 293 ( 4.0A)
FLC  A 293 (-4.3A)
FE  A 292 ( 3.2A)
FE  A 292 ( 3.1A)
 0.29A 1s9aB-3n9tA:
28.0		 1s9aB-3n9tA:
31.56
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1TMX_A_BEZA881_0
(HYDROXYQUINOL
1,2-DIOXYGENASE)		 3n9t PNPC
(Pseudomonas
putida) 		10 / 11 ASP A  80
GLY A 106
PRO A 107
TYR A 160
TYR A 194
ILE A 196
ARG A 215
HIS A 218
HIS A 220
VAL A 248
 FLC  A 293 (-3.6A)
FLC  A 293 ( 4.3A)
FLC  A 293 (-3.5A)
FE  A 292 ( 4.3A)
FLC  A 293 ( 4.0A)
FLC  A 293 (-4.1A)
FLC  A 293 (-4.3A)
FE  A 292 ( 3.2A)
FE  A 292 ( 3.1A)
FLC  A 293 (-4.7A)
 0.49A 1tmxA-3n9tA:
33.0		 1tmxA-3n9tA:
44.41
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1TMX_A_BEZA881_0
(HYDROXYQUINOL
1,2-DIOXYGENASE)		 3n9t PNPC
(Pseudomonas
putida) 		8 / 11 ASP A  80
GLY A 106
PRO A 107
TYR A 194
ILE A 196
ARG A 215
HIS A 218
HIS A 234
 FLC  A 293 (-3.6A)
FLC  A 293 ( 4.3A)
FLC  A 293 (-3.5A)
FLC  A 293 ( 4.0A)
FLC  A 293 (-4.1A)
FLC  A 293 (-4.3A)
FE  A 292 ( 3.2A)
None
 1.30A 1tmxA-3n9tA:
33.0		 1tmxA-3n9tA:
44.41
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1TMX_A_BEZA881_0
(HYDROXYQUINOL
1,2-DIOXYGENASE)		 3n9t PNPC
(Pseudomonas
putida) 		6 / 11 LEU A  77
ASP A  80
TYR A 160
ILE A 196
HIS A 218
VAL A 248
 FLC  A 293 (-4.4A)
FLC  A 293 (-3.6A)
FE  A 292 ( 4.3A)
FLC  A 293 (-4.1A)
FE  A 292 ( 3.2A)
FLC  A 293 (-4.7A)
 1.47A 1tmxA-3n9tA:
33.0		 1tmxA-3n9tA:
44.41
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1TMX_A_BEZA881_0
(HYDROXYQUINOL
1,2-DIOXYGENASE)		 3n9t PNPC
(Pseudomonas
putida) 		9 / 11 LEU A  77
ASP A  80
TYR A 160
TYR A 194
ILE A 196
ARG A 215
HIS A 218
HIS A 220
VAL A 248
 FLC  A 293 (-4.4A)
FLC  A 293 (-3.6A)
FE  A 292 ( 4.3A)
FLC  A 293 ( 4.0A)
FLC  A 293 (-4.1A)
FLC  A 293 (-4.3A)
FE  A 292 ( 3.2A)
FE  A 292 ( 3.1A)
FLC  A 293 (-4.7A)
 0.52A 1tmxA-3n9tA:
33.0		 1tmxA-3n9tA:
44.41
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1TMX_A_BEZA881_0
(HYDROXYQUINOL
1,2-DIOXYGENASE)		 3n9t PNPC
(Pseudomonas
putida) 		7 / 11 LEU A  77
ASP A  80
TYR A 194
ILE A 196
ARG A 215
HIS A 218
HIS A 234
 FLC  A 293 (-4.4A)
FLC  A 293 (-3.6A)
FLC  A 293 ( 4.0A)
FLC  A 293 (-4.1A)
FLC  A 293 (-4.3A)
FE  A 292 ( 3.2A)
None
 1.39A 1tmxA-3n9tA:
33.0		 1tmxA-3n9tA:
44.41
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1TMX_B_BEZB882_0
(HYDROXYQUINOL
1,2-DIOXYGENASE)		 3n9t PNPC
(Pseudomonas
putida) 		5 / 12 ASP A  80
GLY A 106
TYR A 160
HIS A 218
HIS A 234
 FLC  A 293 (-3.6A)
FLC  A 293 ( 4.3A)
FE  A 292 ( 4.3A)
FE  A 292 ( 3.2A)
None
 1.34A 1tmxB-3n9tA:
33.3		 1tmxB-3n9tA:
44.41
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1TMX_B_BEZB882_0
(HYDROXYQUINOL
1,2-DIOXYGENASE)		 3n9t PNPC
(Pseudomonas
putida) 		12 / 12 LEU A  77
ASP A  80
GLY A 106
PRO A 107
TYR A 160
TYR A 194
ILE A 196
ARG A 215
HIS A 218
HIS A 220
HIS A 234
VAL A 248
 FLC  A 293 (-4.4A)
FLC  A 293 (-3.6A)
FLC  A 293 ( 4.3A)
FLC  A 293 (-3.5A)
FE  A 292 ( 4.3A)
FLC  A 293 ( 4.0A)
FLC  A 293 (-4.1A)
FLC  A 293 (-4.3A)
FE  A 292 ( 3.2A)
FE  A 292 ( 3.1A)
None
FLC  A 293 (-4.7A)
 0.47A 1tmxB-3n9tA:
33.3		 1tmxB-3n9tA:
44.41
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1TMX_B_BEZB882_0
(HYDROXYQUINOL
1,2-DIOXYGENASE)		 3n9t PNPC
(Pseudomonas
putida) 		9 / 12 LEU A  77
ASP A  80
GLY A 106
PRO A 107
TYR A 194
ILE A 196
ARG A 215
HIS A 218
HIS A 234
 FLC  A 293 (-4.4A)
FLC  A 293 (-3.6A)
FLC  A 293 ( 4.3A)
FLC  A 293 (-3.5A)
FLC  A 293 ( 4.0A)
FLC  A 293 (-4.1A)
FLC  A 293 (-4.3A)
FE  A 292 ( 3.2A)
None
 1.21A 1tmxB-3n9tA:
33.3		 1tmxB-3n9tA:
44.41
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1TMX_B_BEZB882_0
(HYDROXYQUINOL
1,2-DIOXYGENASE)		 3n9t PNPC
(Pseudomonas
putida) 		7 / 12 LEU A  77
ASP A  80
TYR A 160
ILE A 196
HIS A 218
HIS A 234
VAL A 248
 FLC  A 293 (-4.4A)
FLC  A 293 (-3.6A)
FE  A 292 ( 4.3A)
FLC  A 293 (-4.1A)
FE  A 292 ( 3.2A)
None
FLC  A 293 (-4.7A)
 1.48A 1tmxB-3n9tA:
33.3		 1tmxB-3n9tA:
44.41
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1TMX_B_BEZB882_0
(HYDROXYQUINOL
1,2-DIOXYGENASE)		 3n9t PNPC
(Pseudomonas
putida) 		7 / 12 LEU A  77
PRO A 107
ILE A 196
ARG A 215
HIS A 220
HIS A 218
VAL A 248
 FLC  A 293 (-4.4A)
FLC  A 293 (-3.5A)
FLC  A 293 (-4.1A)
FLC  A 293 (-4.3A)
FE  A 292 ( 3.1A)
FE  A 292 ( 3.2A)
FLC  A 293 (-4.7A)
 1.48A 1tmxB-3n9tA:
33.3		 1tmxB-3n9tA:
44.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A9E_B_REAB1_1
(RETINOIC ACID
RECEPTOR ALPHA)		 3n9t PNPC
(Pseudomonas
putida) 		5 / 11 PHE A 285
ILE A 186
PHE A 184
PHE A 221
LEU A 255
 None
 1.37A 3a9eB-3n9tA:
undetectable		 3a9eB-3n9tA:
19.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DD0_A_EZLA301_1
(CARBONIC ANHYDRASE 2)		 3n9t PNPC
(Pseudomonas
putida) 		5 / 10 HIS A 220
HIS A 218
HIS A 234
VAL A 104
PRO A 197
 FE  A 292 ( 3.1A)
FE  A 292 ( 3.2A)
None
None
FLC  A 293 (-4.6A)
 1.25A 3dd0A-3n9tA:
undetectable		 3dd0A-3n9tA:
23.01
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3HGI_A_BEZA284_0
(CATECHOL
1,2-DIOXYGENASE)		 3n9t PNPC
(Pseudomonas
putida) 		7 / 12 GLY A 106
PRO A 107
TYR A 160
TYR A 194
ARG A 215
HIS A 218
HIS A 220
 FLC  A 293 ( 4.3A)
FLC  A 293 (-3.5A)
FE  A 292 ( 4.3A)
FLC  A 293 ( 4.0A)
FLC  A 293 (-4.3A)
FE  A 292 ( 3.2A)
FE  A 292 ( 3.1A)
 0.34A 3hgiA-3n9tA:
27.9		 3hgiA-3n9tA:
31.13
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3HGI_A_BEZA284_0
(CATECHOL
1,2-DIOXYGENASE)		 3n9t PNPC
(Pseudomonas
putida) 		6 / 12 GLY A 106
PRO A 107
TYR A 194
ARG A 215
HIS A 218
HIS A 234
 FLC  A 293 ( 4.3A)
FLC  A 293 (-3.5A)
FLC  A 293 ( 4.0A)
FLC  A 293 (-4.3A)
FE  A 292 ( 3.2A)
None
 1.39A 3hgiA-3n9tA:
27.9		 3hgiA-3n9tA:
31.13
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3HGI_A_BEZA284_0
(CATECHOL
1,2-DIOXYGENASE)		 3n9t PNPC
(Pseudomonas
putida) 		6 / 12 LEU A  77
GLY A 106
TYR A 194
ARG A 215
HIS A 218
HIS A 220
 FLC  A 293 (-4.4A)
FLC  A 293 ( 4.3A)
FLC  A 293 ( 4.0A)
FLC  A 293 (-4.3A)
FE  A 292 ( 3.2A)
FE  A 292 ( 3.1A)
 0.89A 3hgiA-3n9tA:
27.9		 3hgiA-3n9tA:
31.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TJ7_A_ACTA609_0
(GBAA_1210 PROTEIN)		 3n9t PNPC
(Pseudomonas
putida) 		3 / 3 LYS A 230
VAL A 232
HIS A  93
 None
 1.14A 3tj7A-3n9tA:
undetectable		 3tj7A-3n9tA:
19.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U7S_A_017A202_2
(POL POLYPROTEIN)		 3n9t PNPC
(Pseudomonas
putida) 		5 / 9 GLY A 146
ALA A 147
GLY A 227
LEU A 137
VAL A 136
 None
 0.94A 3u7sB-3n9tA:
undetectable		 3u7sB-3n9tA:
21.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZE1_A_X2NA602_1
(LANOSTEROL 14-ALPHA
DEMETHYLASE)		 3n9t PNPC
(Pseudomonas
putida) 		5 / 12 GLY A 106
PHE A 285
LEU A 219
HIS A 220
PHE A 236
 FLC  A 293 ( 4.3A)
None
None
FE  A 292 ( 3.1A)
None
 1.28A 4ze1A-3n9tA:
undetectable		 4ze1A-3n9tA:
21.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CFS_A_TOYA203_1
(AAD(2''),GENTAMICIN
2''-NUCLEOTIDYLTRANS
FERASE,GENTAMICIN
RESISTANCE PROTEIN)		 3n9t PNPC
(Pseudomonas
putida) 		4 / 8 ASP A 266
TYR A 133
ASP A 268
TYR A 259
 None
 1.02A 5cfsA-3n9tA:
undetectable		 5cfsA-3n9tA:
19.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5V4V_A_NCAA402_0
(NADPH DEHYDROGENASE
3)		 3n9t PNPC
(Pseudomonas
putida) 		4 / 8 HIS A 218
TYR A 194
PHE A 108
PRO A 107
 FE  A 292 ( 3.2A)
FLC  A 293 ( 4.0A)
FLC  A 293 (-4.3A)
FLC  A 293 (-3.5A)
 1.28A 5v4vA-3n9tA:
undetectable		 5v4vA-3n9tA:
21.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5V4V_B_NCAB402_0
(NADPH DEHYDROGENASE
3)		 3n9t PNPC
(Pseudomonas
putida) 		4 / 8 HIS A 218
TYR A 194
PHE A 108
PRO A 107
 FE  A 292 ( 3.2A)
FLC  A 293 ( 4.0A)
FLC  A 293 (-4.3A)
FLC  A 293 (-3.5A)
 1.26A 5v4vB-3n9tA:
undetectable		 5v4vB-3n9tA:
21.23