SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3n9u'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site

Query pattern: Residues from known binding site for annotated drug that match the hit pattern


(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID
Hit
Macromolecule
Res.
Matches
Interface HETATM RMSD Dali
Z-score
Seq.
Identity (%)
View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A3A_A_TEPA1436_1
(CHITINASE)
3n9u CLEAVAGE AND
POLYADENYLATION
SPECIFICITY FACTOR
SUBUNIT 7

(Homo
sapiens)
3 / 3 ASP C 156
PHE C 168
ARG C 158
None
0.91A 2a3aA-3n9uC:
undetectable
2a3aA-3n9uC:
16.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A3B_B_CFFB2434_1
(CHITINASE)
3n9u CLEAVAGE AND
POLYADENYLATION
SPECIFICITY FACTOR
SUBUNIT 7

(Homo
sapiens)
4 / 6 GLU C 153
ASP C 156
PHE C 168
ARG C 158
None
1.38A 2a3bB-3n9uC:
undetectable
2a3bB-3n9uC:
16.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y05_A_RALA802_1
(PROSTAGLANDIN
REDUCTASE 1)
3n9u CLEAVAGE AND
POLYADENYLATION
SPECIFICITY FACTOR
SUBUNIT 7

(Homo
sapiens)
4 / 7 VAL C 101
ASN C 151
GLY C 152
VAL C 155
None
0.82A 2y05A-3n9uC:
undetectable
2y05B-3n9uC:
undetectable
2y05A-3n9uC:
18.99
2y05B-3n9uC:
18.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MUE_A_VIVA302_0
(ALPHA-TOCOPHEROL
TRANSFER PROTEIN)
3n9u CLEAVAGE AND
POLYADENYLATION
SPECIFICITY FACTOR
SUBUNIT 7

(Homo
sapiens)
5 / 12 VAL C 138
LEU C 141
VAL C 107
ILE C 102
PHE C  89
None
0.92A 5mueA-3n9uC:
undetectable
5mueA-3n9uC:
22.73