SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3n9x'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HSH_A_MK1A401_1
(HIV-II PROTEASE)		 3n9x PHOSPHOTRANSFERASE
(Plasmodium
berghei) 		6 / 12 GLY A 174
ALA A 176
ILE A 145
VAL A 170
ILE A 381
ILE A 150
 None
 1.37A 1hshA-3n9xA:
undetectable		 1hshA-3n9xA:
12.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ONI_I_BEZI518_0
(14.5 KDA
TRANSLATIONAL
INHIBITOR PROTEIN)		 3n9x PHOSPHOTRANSFERASE
(Plasmodium
berghei) 		4 / 7 ILE A 150
GLY A 149
PHE A 144
ASN A 143
 None
 0.85A 1oniG-3n9xA:
undetectable
1oniI-3n9xA:
undetectable		 1oniG-3n9xA:
13.86
1oniI-3n9xA:
13.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TW4_A_CHDA130_0
(FATTY ACID-BINDING
PROTEIN)		 3n9x PHOSPHOTRANSFERASE
(Plasmodium
berghei) 		5 / 12 LEU A 365
LEU A 139
ALA A 359
ILE A 354
ILE A 334
 None
 1.15A 1tw4A-3n9xA:
undetectable		 1tw4A-3n9xA:
15.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z11_A_8MOA501_0
(CYTOCHROME P450,
FAMILY 2, SUBFAMILY
A, POLYPEPTIDE 6)		 3n9x PHOSPHOTRANSFERASE
(Plasmodium
berghei) 		5 / 11 PHE A 263
ILE A 296
GLY A 297
ILE A 316
LEU A 289
 None
 0.98A 1z11A-3n9xA:
undetectable		 1z11A-3n9xA:
20.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z11_B_8MOB501_0
(CYTOCHROME P450,
FAMILY 2, SUBFAMILY
A, POLYPEPTIDE 6)		 3n9x PHOSPHOTRANSFERASE
(Plasmodium
berghei) 		5 / 11 PHE A 263
ILE A 296
GLY A 297
ILE A 316
LEU A 289
 None
 0.99A 1z11B-3n9xA:
undetectable		 1z11B-3n9xA:
20.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z11_C_8MOC501_0
(CYTOCHROME P450,
FAMILY 2, SUBFAMILY
A, POLYPEPTIDE 6)		 3n9x PHOSPHOTRANSFERASE
(Plasmodium
berghei) 		5 / 10 PHE A 263
ILE A 296
GLY A 297
ILE A 316
LEU A 289
 None
 1.08A 1z11C-3n9xA:
undetectable		 1z11C-3n9xA:
20.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z11_D_8MOD501_0
(CYTOCHROME P450,
FAMILY 2, SUBFAMILY
A, POLYPEPTIDE 6)		 3n9x PHOSPHOTRANSFERASE
(Plasmodium
berghei) 		5 / 10 PHE A 263
ILE A 296
GLY A 297
ILE A 316
LEU A 289
 None
 1.03A 1z11D-3n9xA:
undetectable		 1z11D-3n9xA:
20.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XAD_E_GCSE710_1
(N-ACYL GLM
PEUDO-TEICOPLANIN
DEACETYLASE
TEICOPLANIN)		 3n9x PHOSPHOTRANSFERASE
(Plasmodium
berghei) 		4 / 8 TRP A 236
ARG A 353
ILE A 296
ASP A 303
 None
 0.93A 2xadA-3n9xA:
undetectable		 2xadA-3n9xA:
19.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XAD_F_GCSF710_1
(N-ACYL GLM
PEUDO-TEICOPLANIN
DEACETYLASE
TEICOPLANIN)		 3n9x PHOSPHOTRANSFERASE
(Plasmodium
berghei) 		4 / 8 TRP A 236
ARG A 353
ILE A 296
ASP A 303
 None
 0.94A 2xadB-3n9xA:
undetectable		 2xadB-3n9xA:
19.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XAD_G_GCSG710_1
(N-ACYL GLM
PEUDO-TEICOPLANIN
DEACETYLASE
TEICOPLANIN)		 3n9x PHOSPHOTRANSFERASE
(Plasmodium
berghei) 		4 / 8 TRP A 236
ARG A 353
ILE A 296
ASP A 303
 None
 0.90A 2xadC-3n9xA:
undetectable		 2xadC-3n9xA:
19.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XAD_H_GCSH710_1
(N-ACYL GLM
PEUDO-TEICOPLANIN
DEACETYLASE
TEICOPLANIN)		 3n9x PHOSPHOTRANSFERASE
(Plasmodium
berghei) 		4 / 8 TRP A 236
ARG A 353
ILE A 296
ASP A 303
 None
 0.85A 2xadD-3n9xA:
undetectable		 2xadD-3n9xA:
19.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y7J_A_B49A1294_1
(PHOSPHORYLASE B
KINASE GAMMA
CATALYTIC CHAIN,
TESTIS/LIVER ISOFORM)		 3n9x PHOSPHOTRANSFERASE
(Plasmodium
berghei) 		6 / 12 ILE A  34
VAL A  42
ALA A  55
ILE A  88
LEU A 161
ASP A 172
 GOL  A 434 ( 4.5A)
None
GOL  A 434 ( 4.1A)
None
GOL  A 434 (-4.2A)
GOL  A 433 (-2.7A)
 0.64A 2y7jA-3n9xA:
23.8		 2y7jA-3n9xA:
24.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y7J_B_B49B1294_1
(PHOSPHORYLASE B
KINASE GAMMA
CATALYTIC CHAIN,
TESTIS/LIVER ISOFORM)		 3n9x PHOSPHOTRANSFERASE
(Plasmodium
berghei) 		6 / 10 ILE A  34
VAL A  42
ALA A  55
ILE A  88
LEU A 161
ASP A 172
 GOL  A 434 ( 4.5A)
None
GOL  A 434 ( 4.1A)
None
GOL  A 434 (-4.2A)
GOL  A 433 (-2.7A)
 0.64A 2y7jB-3n9xA:
24.1		 2y7jB-3n9xA:
24.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EM0_B_CHDB153_0
(ILEAL BILE
ACID-BINDING PROTEIN)		 3n9x PHOSPHOTRANSFERASE
(Plasmodium
berghei) 		4 / 7 ILE A 107
PHE A 102
PHE A  63
GLY A  40
 None
 1.01A 3em0B-3n9xA:
undetectable		 3em0B-3n9xA:
15.24
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3GP0_A_NILA1_1
(MITOGEN-ACTIVATED
PROTEIN KINASE 11)		 3n9x PHOSPHOTRANSFERASE
(Plasmodium
berghei) 		6 / 12 VAL A  42
ALA A  55
GLU A  75
LEU A  79
ILE A  88
HIS A 152
 None
GOL  A 434 ( 4.1A)
GOL  A 433 ( 4.8A)
None
None
None
 1.09A 3gp0A-3n9xA:
33.8		 3gp0A-3n9xA:
32.48
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3HEG_A_BAXA1_1
(MITOGEN-ACTIVATED
PROTEIN KINASE 14)		 3n9x PHOSPHOTRANSFERASE
(Plasmodium
berghei) 		5 / 12 VAL A  42
ALA A  55
LYS A  57
GLU A  75
ILE A 145
 None
GOL  A 434 ( 4.1A)
GOL  A 433 (-3.2A)
GOL  A 433 ( 4.8A)
None
 0.80A 3hegA-3n9xA:
17.6		 3hegA-3n9xA:
32.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LN1_D_CELD682_2
(PROSTAGLANDIN G/H
SYNTHASE 2)		 3n9x PHOSPHOTRANSFERASE
(Plasmodium
berghei) 		4 / 5 ARG A 286
LEU A 224
ARG A 322
ILE A 296
 None
 1.24A 3ln1D-3n9xA:
1.0		 3ln1D-3n9xA:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MJR_A_AC2A301_1
(DEOXYCYTIDINE KINASE)		 3n9x PHOSPHOTRANSFERASE
(Plasmodium
berghei) 		5 / 9 ILE A 307
GLU A 221
ARG A 353
PHE A 348
LEU A 304
 None
 1.16A 3mjrA-3n9xA:
undetectable		 3mjrA-3n9xA:
22.30
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3OHT_A_1N1A1000_1
(P38A)		 3n9x PHOSPHOTRANSFERASE
(Plasmodium
berghei) 		6 / 12 GLY A  35
VAL A  42
ALA A  55
LYS A  57
ILE A  88
LEU A 161
 None
None
GOL  A 434 ( 4.1A)
GOL  A 433 (-3.2A)
None
GOL  A 434 (-4.2A)
 0.93A 3ohtA-3n9xA:
6.7		 3ohtA-3n9xA:
32.83
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3OHT_A_1N1A1000_1
(P38A)		 3n9x PHOSPHOTRANSFERASE
(Plasmodium
berghei) 		6 / 12 GLY A  35
VAL A  42
ALA A  55
LYS A  57
LEU A  79
ILE A  88
 None
None
GOL  A 434 ( 4.1A)
GOL  A 433 (-3.2A)
None
None
 0.65A 3ohtA-3n9xA:
6.7		 3ohtA-3n9xA:
32.83
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3OHT_B_1N1B1000_1
(P38A)		 3n9x PHOSPHOTRANSFERASE
(Plasmodium
berghei) 		6 / 12 GLY A  35
VAL A  42
ALA A  55
LYS A  57
LEU A  79
ILE A  88
 None
None
GOL  A 434 ( 4.1A)
GOL  A 433 (-3.2A)
None
None
 0.63A 3ohtB-3n9xA:
26.2		 3ohtB-3n9xA:
32.83
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3RGF_A_BAXA465_1
(CYCLIN-DEPENDENT
KINASE 8)		 3n9x PHOSPHOTRANSFERASE
(Plasmodium
berghei) 		7 / 12 VAL A  42
ALA A  55
GLU A  75
LEU A  79
ILE A  88
ALA A 112
HIS A 152
 None
GOL  A 434 ( 4.1A)
GOL  A 433 ( 4.8A)
None
None
GOL  A 434 (-3.9A)
None
 1.01A 3rgfA-3n9xA:
21.5		 3rgfA-3n9xA:
31.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UG8_A_IMNA2001_2
(ALDO-KETO REDUCTASE
FAMILY 1 MEMBER C3)		 3n9x PHOSPHOTRANSFERASE
(Plasmodium
berghei) 		3 / 3 TYR A 106
GLU A  75
TYR A  39
 None
GOL  A 433 ( 4.8A)
None
 1.02A 3ug8A-3n9xA:
undetectable		 3ug8A-3n9xA:
21.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C8B_A_0LIA1000_1
(RECEPTOR-INTERACTING
SERINE/THREONINE-PRO
TEIN KINASE 2)		 3n9x PHOSPHOTRANSFERASE
(Plasmodium
berghei) 		7 / 12 ALA A  55
LYS A  57
GLU A  75
LEU A  79
ILE A 107
HIS A 152
LEU A 161
 GOL  A 434 ( 4.1A)
GOL  A 433 (-3.2A)
GOL  A 433 ( 4.8A)
None
None
None
GOL  A 434 (-4.2A)
 0.85A 4c8bA-3n9xA:
20.3		 4c8bA-3n9xA:
28.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C8B_B_0LIB1000_1
(RECEPTOR-INTERACTING
SERINE/THREONINE-PRO
TEIN KINASE 2)		 3n9x PHOSPHOTRANSFERASE
(Plasmodium
berghei) 		7 / 12 ALA A  55
LYS A  57
GLU A  75
LEU A  79
ILE A  87
HIS A 152
LEU A 161
 GOL  A 434 ( 4.1A)
GOL  A 433 (-3.2A)
GOL  A 433 ( 4.8A)
None
None
None
GOL  A 434 (-4.2A)
 0.80A 4c8bB-3n9xA:
12.1		 4c8bB-3n9xA:
28.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4G1B_B_ECNB403_1
(FLAVOHEMOGLOBIN)		 3n9x PHOSPHOTRANSFERASE
(Plasmodium
berghei) 		5 / 11 ILE A 241
THR A 238
PHE A 242
VAL A 168
LEU A 245
 None
 1.14A 4g1bB-3n9xA:
undetectable		 4g1bB-3n9xA:
22.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4G1B_D_ECND403_1
(FLAVOHEMOGLOBIN)		 3n9x PHOSPHOTRANSFERASE
(Plasmodium
berghei) 		6 / 12 ILE A 241
THR A 238
PHE A 242
LEU A 138
VAL A 168
LEU A 245
 None
 1.17A 4g1bD-3n9xA:
undetectable		 4g1bD-3n9xA:
22.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IAA_A_RTZA401_1
(SERINE/THREONINE-PRO
TEIN KINASE PIM-1)		 3n9x PHOSPHOTRANSFERASE
(Plasmodium
berghei) 		5 / 11 VAL A  42
ALA A  55
LYS A  57
LEU A 109
LEU A 161
 None
GOL  A 434 ( 4.1A)
GOL  A 433 (-3.2A)
GOL  A 433 (-4.3A)
GOL  A 434 (-4.2A)
 0.65A 4iaaA-3n9xA:
22.0		 4iaaA-3n9xA:
21.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LVC_B_ADNB501_2
(S-ADENOSYL-L-HOMOCYS
TEINE HYDROLASE
(SAHASE))		 3n9x PHOSPHOTRANSFERASE
(Plasmodium
berghei) 		4 / 5 THR A 238
THR A 133
LEU A 162
LEU A 116
 None
 1.06A 4lvcB-3n9xA:
undetectable		 4lvcB-3n9xA:
20.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OGR_A_ADNA401_1
(CYCLIN-DEPENDENT
KINASE 9)		 3n9x PHOSPHOTRANSFERASE
(Plasmodium
berghei) 		5 / 8 ILE A  34
VAL A  42
ALA A  55
ASP A 115
LEU A 161
 GOL  A 434 ( 4.5A)
None
GOL  A 434 ( 4.1A)
GOL  A 434 (-3.6A)
GOL  A 434 (-4.2A)
 0.56A 4ogrA-3n9xA:
29.5		 4ogrA-3n9xA:
27.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QB9_E_PARE500_1
(ENHANCED
INTRACELLULAR
SURVIVAL PROTEIN)		 3n9x PHOSPHOTRANSFERASE
(Plasmodium
berghei) 		5 / 12 TYR A 217
GLU A  75
ASP A 154
ASP A 172
GLY A  37
 None
GOL  A 433 ( 4.8A)
None
GOL  A 433 (-2.7A)
GOL  A 433 (-3.4A)
 1.43A 4qb9E-3n9xA:
undetectable		 4qb9E-3n9xA:
21.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QMN_A_DB8A401_1
(SERINE/THREONINE-PRO
TEIN KINASE 24)		 3n9x PHOSPHOTRANSFERASE
(Plasmodium
berghei) 		6 / 12 ILE A  34
ALA A  55
LYS A  57
GLU A  75
ILE A 107
LEU A 161
 GOL  A 434 ( 4.5A)
GOL  A 434 ( 4.1A)
GOL  A 433 (-3.2A)
GOL  A 433 ( 4.8A)
None
GOL  A 434 (-4.2A)
 0.79A 4qmnA-3n9xA:
18.0		 4qmnA-3n9xA:
27.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4TYJ_A_0LIA801_1
(FIBROBLAST GROWTH
FACTOR RECEPTOR 4)		 3n9x PHOSPHOTRANSFERASE
(Plasmodium
berghei) 		5 / 12 ALA A  55
GLU A  75
ALA A 112
HIS A 152
LEU A 161
 GOL  A 434 ( 4.1A)
GOL  A 433 ( 4.8A)
GOL  A 434 (-3.9A)
None
GOL  A 434 (-4.2A)
 0.57A 4tyjA-3n9xA:
20.4		 4tyjA-3n9xA:
22.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5A7M_A_ACTA1923_0
(BETA-XYLOSIDASE)		 3n9x PHOSPHOTRANSFERASE
(Plasmodium
berghei) 		3 / 3 ASP A  68
ARG A  71
TYR A  39
 None
 1.05A 5a7mA-3n9xA:
undetectable		 5a7mA-3n9xA:
19.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5A7M_B_ACTB1924_0
(BETA-XYLOSIDASE)		 3n9x PHOSPHOTRANSFERASE
(Plasmodium
berghei) 		3 / 3 ASP A  68
ARG A  71
TYR A  39
 None
 1.01A 5a7mB-3n9xA:
undetectable		 5a7mB-3n9xA:
19.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HES_A_032A401_1
(MITOGEN-ACTIVATED
PROTEIN KINASE
KINASE KINASE MLT)		 3n9x PHOSPHOTRANSFERASE
(Plasmodium
berghei) 		6 / 12 VAL A  42
ALA A  55
ILE A  88
ILE A 107
ALA A 112
CYH A 171
 None
GOL  A 434 ( 4.1A)
None
None
GOL  A 434 (-3.9A)
GOL  A 433 ( 3.7A)
 0.71A 5hesA-3n9xA:
20.0		 5hesA-3n9xA:
27.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HES_B_032B401_1
(MITOGEN-ACTIVATED
PROTEIN KINASE
KINASE KINASE MLT)		 3n9x PHOSPHOTRANSFERASE
(Plasmodium
berghei) 		6 / 12 VAL A  42
ALA A  55
LYS A  57
ILE A 107
ALA A 112
CYH A 171
 None
GOL  A 434 ( 4.1A)
GOL  A 433 (-3.2A)
None
GOL  A 434 (-3.9A)
GOL  A 433 ( 3.7A)
 0.59A 5hesB-3n9xA:
20.0		 5hesB-3n9xA:
27.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I9X_A_DB8A1001_1
(EPHRIN TYPE-A
RECEPTOR 2)		 3n9x PHOSPHOTRANSFERASE
(Plasmodium
berghei) 		7 / 12 ILE A  34
ALA A  55
LYS A  57
GLU A  75
ILE A  88
ILE A 107
LEU A 161
 GOL  A 434 ( 4.5A)
GOL  A 434 ( 4.1A)
GOL  A 433 (-3.2A)
GOL  A 433 ( 4.8A)
None
None
GOL  A 434 (-4.2A)
 0.89A 5i9xA-3n9xA:
20.8		 5i9xA-3n9xA:
23.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LVN_A_ADNA402_1
(3-PHOSPHOINOSITIDE-D
EPENDENT PROTEIN
KINASE 1)		 3n9x PHOSPHOTRANSFERASE
(Plasmodium
berghei) 		6 / 11 GLY A  35
VAL A  42
ALA A  55
LEU A 109
ALA A 112
LEU A 161
 None
None
GOL  A 434 ( 4.1A)
GOL  A 433 (-4.3A)
GOL  A 434 (-3.9A)
GOL  A 434 (-4.2A)
 0.60A 5lvnA-3n9xA:
24.2		 5lvnA-3n9xA:
25.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LW1_B_ADNB401_1
(MITOGEN-ACTIVATED
PROTEIN KINASE 8)		 3n9x PHOSPHOTRANSFERASE
(Plasmodium
berghei) 		6 / 9 ILE A  34
GLY A  35
VAL A  42
ALA A  55
ILE A  88
LEU A 161
 GOL  A 434 ( 4.5A)
None
None
GOL  A 434 ( 4.1A)
None
GOL  A 434 (-4.2A)
 1.38A 5lw1B-3n9xA:
23.8		 5lw1B-3n9xA:
17.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MAF_A_XINA403_1
(MATERNAL EMBRYONIC
LEUCINE ZIPPER
KINASE)		 3n9x PHOSPHOTRANSFERASE
(Plasmodium
berghei) 		7 / 12 ILE A  34
GLY A  35
VAL A  42
ALA A  55
LYS A  57
GLU A  75
LEU A 109
 GOL  A 434 ( 4.5A)
None
None
GOL  A 434 ( 4.1A)
GOL  A 433 (-3.2A)
GOL  A 433 ( 4.8A)
GOL  A 433 (-4.3A)
 0.70A 5mafA-3n9xA:
24.6		 5mafA-3n9xA:
11.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X66_D_MTXD402_1
(THYMIDYLATE SYNTHASE)		 3n9x PHOSPHOTRANSFERASE
(Plasmodium
berghei) 		5 / 10 ARG A 397
PHE A 400
ILE A  76
ASP A  92
TYR A  28
 None
 1.46A 5x66D-3n9xA:
undetectable		 5x66D-3n9xA:
21.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZV2_A_LEVA801_2
(FIBROBLAST GROWTH
FACTOR RECEPTOR 1)		 3n9x PHOSPHOTRANSFERASE
(Plasmodium
berghei) 		3 / 3 LYS A  57
LEU A 161
ASP A 172
 GOL  A 433 (-3.2A)
GOL  A 434 (-4.2A)
GOL  A 433 (-2.7A)
 0.83A 5zv2A-3n9xA:
20.2		 5zv2A-3n9xA:
13.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZV2_A_LEVA801_2
(FIBROBLAST GROWTH
FACTOR RECEPTOR 1)		 3n9x PHOSPHOTRANSFERASE
(Plasmodium
berghei) 		3 / 3 LYS A 211
LEU A 175
ASP A  68
 None
 0.76A 5zv2A-3n9xA:
20.2		 5zv2A-3n9xA:
13.11