SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3na8'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MXG_A_ACRA443_1
(ALPHA AMYLASE)		 3na8 PUTATIVE
DIHYDRODIPICOLINATE
SYNTHETASE
(Pseudomonas
aeruginosa) 		4 / 8 SER A 187
ASN A 157
ASP A 165
GLU A 135
 CSO  A 211 ( 4.0A)
None
None
None
 1.09A 1mxgA-3na8A:
9.5		 1mxgA-3na8A:
23.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RU9_H_ACTH611_0
(IMMUNOGLOBULIN
IGG2A, HEAVY CHAIN
IMMUNOGLOBULIN
IGG2A, LIGHT CHAIN)		 3na8 PUTATIVE
DIHYDRODIPICOLINATE
SYNTHETASE
(Pseudomonas
aeruginosa) 		4 / 6 LEU A 264
ASN A 238
LEU A 241
TRP A 226
 None
 1.42A 1ru9H-3na8A:
undetectable
1ru9L-3na8A:
undetectable		 1ru9H-3na8A:
20.94
1ru9L-3na8A:
21.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RUA_L_ACTL611_0
(IMMUNOGLOBULIN
IGG2A, HEAVY CHAIN
IMMUNOGLOBULIN
IGG2A, LIGHT CHAIN)		 3na8 PUTATIVE
DIHYDRODIPICOLINATE
SYNTHETASE
(Pseudomonas
aeruginosa) 		4 / 5 LEU A 264
ASN A 238
LEU A 241
TRP A 226
 None
 1.46A 1ruaH-3na8A:
0.0
1ruaL-3na8A:
undetectable		 1ruaH-3na8A:
20.94
1ruaL-3na8A:
21.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RUK_L_ACTL611_0
(IMMUNOGLOBULIN
IGG2A, HEAVY CHAIN
IMMUNOGLOBULIN
IGG2A, LIGHT CHAIN)		 3na8 PUTATIVE
DIHYDRODIPICOLINATE
SYNTHETASE
(Pseudomonas
aeruginosa) 		4 / 6 LEU A 264
ASN A 238
LEU A 241
TRP A 226
 None
 1.44A 1rukH-3na8A:
undetectable
1rukL-3na8A:
undetectable		 1rukH-3na8A:
20.94
1rukL-3na8A:
21.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RUL_L_ACTL611_0
(IMMUNOGLOBULIN
IGG2A, HEAVY CHAIN
IMMUNOGLOBULIN
IGG2A, LIGHT CHAIN)		 3na8 PUTATIVE
DIHYDRODIPICOLINATE
SYNTHETASE
(Pseudomonas
aeruginosa) 		4 / 5 LEU A 264
ASN A 238
LEU A 241
TRP A 226
 None
 1.47A 1rulH-3na8A:
0.0
1rulL-3na8A:
undetectable		 1rulH-3na8A:
20.94
1rulL-3na8A:
21.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2CIZ_A_ACTA1321_0
(CHLOROPEROXIDASE)		 3na8 PUTATIVE
DIHYDRODIPICOLINATE
SYNTHETASE
(Pseudomonas
aeruginosa) 		4 / 5 LEU A  87
PHE A 114
VAL A  98
ALA A 120
 None
 1.20A 2cizA-3na8A:
undetectable		 2cizA-3na8A:
20.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q83_B_ADNB2_1
(YTAA PROTEIN)		 3na8 PUTATIVE
DIHYDRODIPICOLINATE
SYNTHETASE
(Pseudomonas
aeruginosa) 		4 / 6 ILE A  62
PRO A  35
LEU A 280
ILE A  33
 None
 1.03A 2q83B-3na8A:
undetectable		 2q83B-3na8A:
22.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XAT_A_CLMA301_0
(XENOBIOTIC
ACETYLTRANSFERASE)		 3na8 PUTATIVE
DIHYDRODIPICOLINATE
SYNTHETASE
(Pseudomonas
aeruginosa) 		3 / 3 GLY A  66
TYR A  31
SER A  67
 None
 0.76A 2xatA-3na8A:
undetectable		 2xatA-3na8A:
22.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IX9_B_MTXB200_1
(DIHYDROFOLATE
REDUCTASE)		 3na8 PUTATIVE
DIHYDRODIPICOLINATE
SYNTHETASE
(Pseudomonas
aeruginosa) 		5 / 12 LEU A 155
GLU A 186
LEU A 197
ARG A 176
THR A 188
 None
 1.05A 3ix9B-3na8A:
undetectable		 3ix9B-3na8A:
22.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SI7_A_ACTA4_0
(CYSTIC FIBROSIS
TRANSMEMBRANE
CONDUCTANCE
REGULATOR)		 3na8 PUTATIVE
DIHYDRODIPICOLINATE
SYNTHETASE
(Pseudomonas
aeruginosa) 		4 / 4 LEU A  65
GLY A  66
GLY A  69
THR A  32
 None
 0.95A 3si7A-3na8A:
undetectable		 3si7A-3na8A:
23.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ACB_C_DXCC1478_0
(TRANSLATION
ELONGATION FACTOR
SELB)		 3na8 PUTATIVE
DIHYDRODIPICOLINATE
SYNTHETASE
(Pseudomonas
aeruginosa) 		4 / 6 ASP A  43
THR A  32
ILE A  33
PHE A  36
 None
 0.96A 4acbC-3na8A:
2.6		 4acbC-3na8A:
23.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4I90_A_ACTA500_0
(1-PHOSPHATIDYLINOSIT
OL PHOSPHODIESTERASE)		 3na8 PUTATIVE
DIHYDRODIPICOLINATE
SYNTHETASE
(Pseudomonas
aeruginosa) 		3 / 3 LYS A 107
ARG A 111
TRP A  79
 None
 1.14A 4i90A-3na8A:
1.4		 4i90A-3na8A:
21.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LTW_A_486A303_1
(ANCESTRAL STEROID
RECEPTOR 2)		 3na8 PUTATIVE
DIHYDRODIPICOLINATE
SYNTHETASE
(Pseudomonas
aeruginosa) 		5 / 9 THR A  68
LEU A 272
ALA A 229
LEU A 264
THR A 275
 None
 1.22A 4ltwA-3na8A:
undetectable		 4ltwA-3na8A:
20.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DZK_R_BEZR801_1
(ATP-DEPENDENT CLP
PROTEASE PROTEOLYTIC
SUBUNIT 2
BEZ-LEU-LEU)		 3na8 PUTATIVE
DIHYDRODIPICOLINATE
SYNTHETASE
(Pseudomonas
aeruginosa) 		4 / 8 SER A 228
ALA A 229
LEU A 264
LEU A 268
 None
 0.91A 5dzkd-3na8A:
3.0
5dzkr-3na8A:
undetectable		 5dzkd-3na8A:
22.87
5dzkr-3na8A:
1.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HHJ_A_GLYA403_0
(RETRON-TYPE REVERSE
TRANSCRIPTASE)		 3na8 PUTATIVE
DIHYDRODIPICOLINATE
SYNTHETASE
(Pseudomonas
aeruginosa) 		4 / 4 LEU A  74
LEU A  65
GLY A  69
GLU A  70
 None
 1.23A 5hhjA-3na8A:
undetectable		 5hhjA-3na8A:
21.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MSD_A_BEZA1202_0
(CARBOXYLIC ACID
REDUCTASE)		 3na8 PUTATIVE
DIHYDRODIPICOLINATE
SYNTHETASE
(Pseudomonas
aeruginosa) 		4 / 5 HIS A 195
ILE A 191
PHE A 207
ALA A 218
 None
 0.91A 5msdA-3na8A:
4.0		 5msdA-3na8A:
14.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TIW_A_OAQA302_0
(SULFOTRANSFERASE)		 3na8 PUTATIVE
DIHYDRODIPICOLINATE
SYNTHETASE
(Pseudomonas
aeruginosa) 		5 / 12 ILE A 276
LEU A 268
ILE A 234
LEU A 280
LEU A  54
 None
 1.03A 5tiwA-3na8A:
undetectable		 5tiwA-3na8A:
21.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AYC_A_1YNA502_2
(PROTEIN CYP51)		 3na8 PUTATIVE
DIHYDRODIPICOLINATE
SYNTHETASE
(Pseudomonas
aeruginosa) 		4 / 7 VAL A 245
LEU A 233
PHE A 257
LEU A 264
 None
 1.17A 6aycA-3na8A:
undetectable		 6aycA-3na8A:
13.97