SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3nab'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)	View	Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2EIM_J_CHDJ60_0 (CYTOCHROME C OXIDASE POLYPEPTIDE VIIA-HEART)	3nab	FAB15 MUT6 HEAVY CHAIN (Homo sapiens)	4 / 5	TYR H 91 MET H 89 THR H 107 LEU H 108	None	1.34A	2eimJ-3nabH: undetectable	2eimJ-3nabH: 14.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2EIM_W_CHDW1060_0 (CYTOCHROME C OXIDASE POLYPEPTIDE VIIA-HEART)	3nab	FAB15 MUT6 HEAVY CHAIN (Homo sapiens)	4 / 5	TYR H 91 MET H 89 THR H 107 LEU H 108	None	1.33A	2eimW-3nabH: undetectable	2eimW-3nabH: 14.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3AG2_J_CHDJ60_0 (CYTOCHROME C OXIDASE POLYPEPTIDE 7A1)	3nab	FAB15 MUT6 HEAVY CHAIN (Homo sapiens)	4 / 5	TYR H 91 MET H 89 THR H 107 LEU H 108	None	1.32A	3ag2J-3nabH: undetectable	3ag2J-3nabH: 14.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3AG4_J_CHDJ60_0 (CYTOCHROME C OXIDASE POLYPEPTIDE 7A1)	3nab	FAB15 MUT6 HEAVY CHAIN (Homo sapiens)	4 / 5	TYR H 91 MET H 89 THR H 107 LEU H 108	None	1.33A	3ag4J-3nabH: undetectable	3ag4J-3nabH: 14.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4P7N_A_GCSA702_1 (POLY-BETA-1,6-N-ACET YL-D-GLUCOSAMINE N-DEACETYLASE)	3nab	FAB15 MUT6 HEAVY CHAIN (Homo sapiens)	3 / 3	ASP H 100 TYR H 97 TRP H 33	None	1.02A	4p7nA-3nabH: undetectable	4p7nA-3nabH: 19.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5WAU_J_CHDJ101_1 (CYTOCHROME C OXIDASE SUBUNIT 7A1, MITOCHONDRIAL)	3nab	FAB15 MUT6 HEAVY CHAIN (Homo sapiens)	4 / 5	TYR H 91 MET H 89 THR H 107 LEU H 108	None	1.36A	5wauJ-3nabH: undetectable	5wauJ-3nabH: 14.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5X1B_W_CHDW101_0 (CYTOCHROME C OXIDASE SUBUNIT 7A1, MITOCHONDRIAL)	3nab	FAB15 MUT6 HEAVY CHAIN (Homo sapiens)	4 / 5	TYR H 91 MET H 89 THR H 107 LEU H 108	None	1.38A	5x1bW-3nabH: undetectable	5x1bW-3nabH: 14.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5Z86_J_CHDJ101_0 (CYTOCHROME C OXIDASE SUBUNIT 7A1, MITOCHONDRIAL)	3nab	FAB15 MUT6 HEAVY CHAIN (Homo sapiens)	4 / 5	TYR H 91 MET H 89 THR H 107 LEU H 108	None	1.33A	5z86J-3nabH: undetectable	5z86J-3nabH: 14.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6BPY_A_ACTA408_0 (THIOREDOXIN REDUCTASE)	3nab	FAB15 MUT6 HEAVY CHAIN (Homo sapiens)	3 / 3	PRO H 185 SER H 187 SER H 188	None	0.54A	6bpyA-3nabH: undetectable	6bpyA-3nabH: 21.45

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["2EIM_J_CHDJ60_0","CYTOCHROME C OXIDASE POLYPEPTIDE VIIA-HEART","3nab","FAB15 MUT6 HEAVY CHAIN","Homo sapiens",4,"TYR H  91;MET H  89;THR H 107;LEU H 108","None","1.34A","2eimJ-3nabH:undetectable","2eimJ-3nabH:14.86"],["2EIM_W_CHDW1060_0","CYTOCHROME C OXIDASE POLYPEPTIDE VIIA-HEART","3nab","FAB15 MUT6 HEAVY CHAIN","Homo sapiens",4,"TYR H  91;MET H  89;THR H 107;LEU H 108","None","1.33A","2eimW-3nabH:undetectable","2eimW-3nabH:14.86"],["3AG2_J_CHDJ60_0","CYTOCHROME C OXIDASE POLYPEPTIDE 7A1","3nab","FAB15 MUT6 HEAVY CHAIN","Homo sapiens",4,"TYR H  91;MET H  89;THR H 107;LEU H 108","None","1.32A","3ag2J-3nabH:undetectable","3ag2J-3nabH:14.86"],["3AG4_J_CHDJ60_0","CYTOCHROME C OXIDASE POLYPEPTIDE 7A1","3nab","FAB15 MUT6 HEAVY CHAIN","Homo sapiens",4,"TYR H  91;MET H  89;THR H 107;LEU H 108","None","1.33A","3ag4J-3nabH:undetectable","3ag4J-3nabH:14.86"],["4P7N_A_GCSA702_1","POLY-BETA-1,6-N-ACETYL-D-GLUCOSAMINE N-DEACETYLASE","3nab","FAB15 MUT6 HEAVY CHAIN","Homo sapiens",3,"ASP H 100;TYR H  97;TRP H  33","None","1.02A","4p7nA-3nabH:undetectable","4p7nA-3nabH:19.78"],["5WAU_J_CHDJ101_1","CYTOCHROME C OXIDASE SUBUNIT 7A1, MITOCHONDRIAL","3nab","FAB15 MUT6 HEAVY CHAIN","Homo sapiens",4,"TYR H  91;MET H  89;THR H 107;LEU H 108","None","1.36A","5wauJ-3nabH:undetectable","5wauJ-3nabH:14.86"],["5X1B_W_CHDW101_0","CYTOCHROME C OXIDASE SUBUNIT 7A1, MITOCHONDRIAL","3nab","FAB15 MUT6 HEAVY CHAIN","Homo sapiens",4,"TYR H  91;MET H  89;THR H 107;LEU H 108","None","1.38A","5x1bW-3nabH:undetectable","5x1bW-3nabH:14.86"],["5Z86_J_CHDJ101_0","CYTOCHROME C OXIDASE SUBUNIT 7A1, MITOCHONDRIAL","3nab","FAB15 MUT6 HEAVY CHAIN","Homo sapiens",4,"TYR H  91;MET H  89;THR H 107;LEU H 108","None","1.33A","5z86J-3nabH:undetectable","5z86J-3nabH:14.86"],["6BPY_A_ACTA408_0","THIOREDOXIN REDUCTASE","3nab","FAB15 MUT6 HEAVY CHAIN","Homo sapiens",3,"PRO H 185;SER H 187;SER H 188","None","0.54A","6bpyA-3nabH:undetectable","6bpyA-3nabH:21.45"]]