SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3nad'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RK3_A_VDXA500_2
(VITAMIN D3 RECEPTOR)		 3nad FERULATE
DECARBOXYLASE
(Bacillus
pumilus) 		4 / 4 LEU A  72
ILE A 144
ARG A  44
TYR A  19
 None
 1.29A 1rk3A-3nadA:
undetectable		 1rk3A-3nadA:
17.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V54_C_CHDC3525_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE I
CYTOCHROME C OXIDASE
POLYPEPTIDE III)		 3nad FERULATE
DECARBOXYLASE
(Bacillus
pumilus) 		4 / 7 ASP A 129
THR A  12
TYR A  13
HIS A   8
 None
 1.47A 1v54A-3nadA:
undetectable
1v54C-3nadA:
undetectable		 1v54A-3nadA:
13.51
1v54C-3nadA:
18.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V54_P_CHDP4525_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE I
CYTOCHROME C OXIDASE
POLYPEPTIDE III)		 3nad FERULATE
DECARBOXYLASE
(Bacillus
pumilus) 		4 / 7 ASP A 129
THR A  12
TYR A  13
HIS A   8
 None
 1.49A 1v54N-3nadA:
undetectable
1v54P-3nadA:
undetectable		 1v54N-3nadA:
13.51
1v54P-3nadA:
18.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V55_C_CHDC3525_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE I
CYTOCHROME C OXIDASE
POLYPEPTIDE III)		 3nad FERULATE
DECARBOXYLASE
(Bacillus
pumilus) 		4 / 7 ASP A 129
THR A  12
TYR A  13
HIS A   8
 None
 1.46A 1v55A-3nadA:
undetectable
1v55C-3nadA:
undetectable		 1v55A-3nadA:
13.51
1v55C-3nadA:
18.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2D55_C_DVAC2_0
(ACTINOMYCIN D)		 3nad FERULATE
DECARBOXYLASE
(Bacillus
pumilus) 		3 / 3 THR A 118
PRO A 120
PRO A  88
 None
 0.49A 2d55C-3nadA:
undetectable		 2d55C-3nadA:
11.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2D55_C_DVAC8_0
(ACTINOMYCIN D)		 3nad FERULATE
DECARBOXYLASE
(Bacillus
pumilus) 		3 / 3 PRO A  88
THR A 118
PRO A 120
 None
 0.82A 2d55C-3nadA:
undetectable		 2d55C-3nadA:
11.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DYR_P_CHDP1525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3nad FERULATE
DECARBOXYLASE
(Bacillus
pumilus) 		4 / 7 ASP A 129
THR A  12
TYR A  13
HIS A   8
 None
 1.50A 2dyrN-3nadA:
undetectable
2dyrP-3nadA:
undetectable		 2dyrN-3nadA:
13.51
2dyrP-3nadA:
18.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DYS_P_CHDP304_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3nad FERULATE
DECARBOXYLASE
(Bacillus
pumilus) 		4 / 6 ASP A 129
THR A  12
TYR A  13
HIS A   8
 None
 1.46A 2dysN-3nadA:
undetectable
2dysP-3nadA:
undetectable		 2dysN-3nadA:
13.51
2dysP-3nadA:
18.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIK_C_CHDC525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3nad FERULATE
DECARBOXYLASE
(Bacillus
pumilus) 		4 / 7 ASP A 129
THR A  12
TYR A  13
HIS A   8
 None
 1.46A 2eikA-3nadA:
undetectable
2eikC-3nadA:
undetectable		 2eikA-3nadA:
13.51
2eikC-3nadA:
18.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIL_P_CHDP1525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3nad FERULATE
DECARBOXYLASE
(Bacillus
pumilus) 		4 / 7 ASP A 129
THR A  12
TYR A  13
HIS A   8
 None
 1.49A 2eilN-3nadA:
undetectable
2eilP-3nadA:
undetectable		 2eilN-3nadA:
13.51
2eilP-3nadA:
18.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIM_A_CHDA525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3nad FERULATE
DECARBOXYLASE
(Bacillus
pumilus) 		4 / 6 ASP A 129
THR A  12
TYR A  13
HIS A   8
 None
 1.41A 2eimA-3nadA:
undetectable
2eimC-3nadA:
undetectable		 2eimA-3nadA:
13.51
2eimC-3nadA:
18.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIM_P_CHDP1525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3nad FERULATE
DECARBOXYLASE
(Bacillus
pumilus) 		4 / 6 ASP A 129
THR A  12
TYR A  13
HIS A   8
 None
 1.47A 2eimN-3nadA:
undetectable
2eimP-3nadA:
undetectable		 2eimN-3nadA:
13.51
2eimP-3nadA:
18.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIN_C_CHDC525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3nad FERULATE
DECARBOXYLASE
(Bacillus
pumilus) 		4 / 6 ASP A 129
THR A  12
TYR A  13
HIS A   8
 None
 1.38A 2einA-3nadA:
undetectable
2einC-3nadA:
undetectable		 2einA-3nadA:
13.51
2einC-3nadA:
18.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIN_P_CHDP1525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3nad FERULATE
DECARBOXYLASE
(Bacillus
pumilus) 		4 / 6 ASP A 129
THR A  12
TYR A  13
HIS A   8
 None
 1.42A 2einN-3nadA:
undetectable
2einP-3nadA:
undetectable		 2einN-3nadA:
13.51
2einP-3nadA:
18.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YK1_H_NCTH300_1
(FAB FRAGMENT, HEAVY
CHAIN
FAB FRAGMENT, LIGHT
CHAIN)		 3nad FERULATE
DECARBOXYLASE
(Bacillus
pumilus) 		5 / 10 ILE A  33
GLY A  36
SER A  35
TYR A  11
ALA A 128
 None
 1.35A 2yk1H-3nadA:
0.0
2yk1L-3nadA:
0.6		 2yk1H-3nadA:
17.81
2yk1L-3nadA:
19.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZLC_A_VDXA500_2
(VITAMIN D3 RECEPTOR)		 3nad FERULATE
DECARBOXYLASE
(Bacillus
pumilus) 		4 / 5 LEU A  72
ILE A 144
ARG A  44
TYR A  19
 None
 1.34A 2zlcA-3nadA:
undetectable		 2zlcA-3nadA:
18.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZXW_P_CHDP1525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3nad FERULATE
DECARBOXYLASE
(Bacillus
pumilus) 		4 / 6 ASP A 129
THR A  12
TYR A  13
HIS A   8
 None
 1.47A 2zxwN-3nadA:
undetectable
2zxwP-3nadA:
undetectable		 2zxwN-3nadA:
13.51
2zxwP-3nadA:
18.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABM_P_CHDP1525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3nad FERULATE
DECARBOXYLASE
(Bacillus
pumilus) 		4 / 7 ASP A 129
THR A  12
TYR A  13
HIS A   8
 None
 1.48A 3abmN-3nadA:
undetectable
3abmP-3nadA:
undetectable		 3abmN-3nadA:
13.51
3abmP-3nadA:
18.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG4_P_CHDP1525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3nad FERULATE
DECARBOXYLASE
(Bacillus
pumilus) 		4 / 7 ASP A 129
THR A  12
TYR A  13
HIS A   8
 None
 1.47A 3ag4N-3nadA:
undetectable
3ag4P-3nadA:
undetectable		 3ag4N-3nadA:
13.51
3ag4P-3nadA:
18.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ASN_C_CHDC525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3nad FERULATE
DECARBOXYLASE
(Bacillus
pumilus) 		4 / 6 ASP A 129
THR A  12
TYR A  13
HIS A   8
 None
 1.45A 3asnA-3nadA:
undetectable
3asnC-3nadA:
undetectable		 3asnA-3nadA:
13.51
3asnC-3nadA:
18.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LNW_A_T3A501_2
(THYROID HORMONE
RECEPTOR ALPHA)		 3nad FERULATE
DECARBOXYLASE
(Bacillus
pumilus) 		3 / 3 ILE A  10
MET A  81
ARG A  80
 None
 0.94A 4lnwA-3nadA:
undetectable		 4lnwA-3nadA:
20.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LNX_A_T3A502_2
(THYROID HORMONE
RECEPTOR ALPHA)		 3nad FERULATE
DECARBOXYLASE
(Bacillus
pumilus) 		3 / 3 ILE A  10
MET A  81
ARG A  80
 None
 0.95A 4lnxA-3nadA:
undetectable		 4lnxA-3nadA:
20.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IY5_C_CHDC301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3nad FERULATE
DECARBOXYLASE
(Bacillus
pumilus) 		4 / 7 ASP A 129
THR A  12
TYR A  13
HIS A   8
 None
 1.45A 5iy5A-3nadA:
undetectable
5iy5C-3nadA:
undetectable		 5iy5A-3nadA:
13.51
5iy5C-3nadA:
18.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X1B_P_CHDP306_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3nad FERULATE
DECARBOXYLASE
(Bacillus
pumilus) 		4 / 6 ASP A 129
THR A  12
TYR A  13
HIS A   8
 None
 1.45A 5x1bN-3nadA:
undetectable
5x1bP-3nadA:
undetectable		 5x1bN-3nadA:
13.51
5x1bP-3nadA:
18.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X1F_P_CHDP305_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3nad FERULATE
DECARBOXYLASE
(Bacillus
pumilus) 		4 / 7 ASP A 129
THR A  12
TYR A  13
HIS A   8
 None
 1.48A 5x1fN-3nadA:
undetectable
5x1fP-3nadA:
undetectable		 5x1fN-3nadA:
13.51
5x1fP-3nadA:
18.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCQ_P_CHDP301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3nad FERULATE
DECARBOXYLASE
(Bacillus
pumilus) 		4 / 7 ASP A 129
THR A  12
TYR A  13
HIS A   8
 None
 1.48A 5zcqN-3nadA:
undetectable
5zcqP-3nadA:
undetectable		 5zcqN-3nadA:
13.51
5zcqP-3nadA:
18.35