SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3nas'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)	View	Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1RMT_B_ADNB1502_1 (CLASS B ACID PHOSPHATASE)	3nas	BETA-PHOSPHOGLUCOMUT ASE (Bacillus subtilis)	4 / 7	GLU A 52 LEU A 51 THR A 65 TYR A 64	None	1.08A	1rmtB-3nasA: 8.4	1rmtB-3nasA: 22.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2BYO_A_LNLA1217_1 (LIPOPROTEIN LPPX)	3nas	BETA-PHOSPHOGLUCOMUT ASE (Bacillus subtilis)	4 / 4	VAL A 188 LEU A 100 ILE A 110 LEU A 112	None	0.99A	2byoA-3nasA: undetectable	2byoA-3nasA: 23.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2M9Q_B_BEZB251_0 (SERINE PROTEASE INHIBITOR SERINE PROTEASE SUBUNIT NS2B, SERINE PROTEASE NS3)	3nas	BETA-PHOSPHOGLUCOMUT ASE (Bacillus subtilis)	5 / 9	LEU A 126 ILE A 96 PHE A 132 THR A 13 LEU A 123	None	1.12A	2m9qA-3nasA: undetectable	2m9qA-3nasA: 22.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2W3B_B_FOLB401_0 (DIHYDROFOLATE REDUCTASE)	3nas	BETA-PHOSPHOGLUCOMUT ASE (Bacillus subtilis)	5 / 12	ILE A 129 ALA A 119 LEU A 8 ILE A 96 LEU A 100	None	1.17A	2w3bB-3nasA: 2.9	2w3bB-3nasA: 21.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4KJJ_A_FOLA201_0 (DIHYDROFOLATE REDUCTASE)	3nas	BETA-PHOSPHOGLUCOMUT ASE (Bacillus subtilis)	6 / 12	ALA A 119 ALA A 134 PHE A 132 ILE A 96 LEU A 100 ILE A 128	None	1.44A	4kjjA-3nasA: undetectable	4kjjA-3nasA: 20.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4KJJ_A_FOLA201_0 (DIHYDROFOLATE REDUCTASE)	3nas	BETA-PHOSPHOGLUCOMUT ASE (Bacillus subtilis)	5 / 12	ILE A 129 ALA A 119 ALA A 134 LEU A 100 ILE A 128	None	1.02A	4kjjA-3nasA: undetectable	4kjjA-3nasA: 20.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6EBP_C_DAHC123_0 (RIBONUCLEOSIDE-DIPHO SPHATE REDUCTASE, BETA SUBUNIT)	3nas	BETA-PHOSPHOGLUCOMUT ASE (Bacillus subtilis)	5 / 10	LEU A 8 ASP A 7 GLY A 111 ILE A 135 PHE A 132	None	1.15A	6ebpC-3nasA: undetectable	6ebpC-3nasA: 15.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6EBP_D_DAHD123_0 (RIBONUCLEOSIDE-DIPHO SPHATE REDUCTASE, BETA SUBUNIT)	3nas	BETA-PHOSPHOGLUCOMUT ASE (Bacillus subtilis)	5 / 10	LEU A 8 ASP A 7 GLY A 111 ILE A 135 PHE A 132	None	1.13A	6ebpD-3nasA: undetectable	6ebpD-3nasA: 15.46

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["1RMT_B_ADNB1502_1","CLASS B ACID PHOSPHATASE","3nas","BETA-PHOSPHOGLUCOMUTASE","Bacillus subtilis",4,"GLU A  52;LEU A  51;THR A  65;TYR A  64","None","1.08A","1rmtB-3nasA:8.4","1rmtB-3nasA:22.71"],["2BYO_A_LNLA1217_1","LIPOPROTEIN LPPX","3nas","BETA-PHOSPHOGLUCOMUTASE","Bacillus subtilis",4,"VAL A 188;LEU A 100;ILE A 110;LEU A 112","None","0.99A","2byoA-3nasA:undetectable","2byoA-3nasA:23.79"],["2M9Q_B_BEZB251_0","SERINE PROTEASE INHIBITOR;SERINE PROTEASE SUBUNIT NS2B, SERINE PROTEASE NS3","3nas","BETA-PHOSPHOGLUCOMUTASE","Bacillus subtilis",5,"LEU A 126;ILE A  96;PHE A 132;THR A  13;LEU A 123","None","1.12A","2m9qA-3nasA:undetectable","2m9qA-3nasA:22.71"],["2W3B_B_FOLB401_0","DIHYDROFOLATE REDUCTASE","3nas","BETA-PHOSPHOGLUCOMUTASE","Bacillus subtilis",5,"ILE A 129;ALA A 119;LEU A   8;ILE A  96;LEU A 100","None","1.17A","2w3bB-3nasA:2.9","2w3bB-3nasA:21.25"],["4KJJ_A_FOLA201_0","DIHYDROFOLATE REDUCTASE","3nas","BETA-PHOSPHOGLUCOMUTASE","Bacillus subtilis",6,"ALA A 119;ALA A 134;PHE A 132;ILE A  96;LEU A 100;ILE A 128","None","1.44A","4kjjA-3nasA:undetectable","4kjjA-3nasA:20.69"],["4KJJ_A_FOLA201_0","DIHYDROFOLATE REDUCTASE","3nas","BETA-PHOSPHOGLUCOMUTASE","Bacillus subtilis",5,"ILE A 129;ALA A 119;ALA A 134;LEU A 100;ILE A 128","None","1.02A","4kjjA-3nasA:undetectable","4kjjA-3nasA:20.69"],["6EBP_C_DAHC123_0","RIBONUCLEOSIDE-DIPHOSPHATE REDUCTASE, BETA SUBUNIT","3nas","BETA-PHOSPHOGLUCOMUTASE","Bacillus subtilis",5,"LEU A   8;ASP A   7;GLY A 111;ILE A 135;PHE A 132","None","1.15A","6ebpC-3nasA:undetectable","6ebpC-3nasA:15.46"],["6EBP_D_DAHD123_0","RIBONUCLEOSIDE-DIPHOSPHATE REDUCTASE, BETA SUBUNIT","3nas","BETA-PHOSPHOGLUCOMUTASE","Bacillus subtilis",5,"LEU A   8;ASP A   7;GLY A 111;ILE A 135;PHE A 132","None","1.13A","6ebpD-3nasA:undetectable","6ebpD-3nasA:15.46"]]