SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3nat'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1AQB_A_RTLA185_0 (RETINOL-BINDING PROTEIN)	3nat	UNCHARACTERIZED PROTEIN (Enterococcus faecalis)	5 / 10	LEU A 133 VAL A 38 MET A 143 TYR A 107 LEU A 69	None	1.45A	1aqbA-3natA: undetectable	1aqbA-3natA: 25.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2YVL_A_SAMA601_1 (HYPOTHETICAL PROTEIN)	3nat	UNCHARACTERIZED PROTEIN (Enterococcus faecalis)	4 / 4	GLU A 83 ASP A 81 ASP A 28 TYR A 72	None CIT A 162 ( 3.3A) None ZN A 165 ( 4.9A)	1.16A	2yvlA-3natA: 0.0	2yvlA-3natA: 24.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4XJE_A_TOYA202_1 (AADB)	3nat	UNCHARACTERIZED PROTEIN (Enterococcus faecalis)	4 / 8	ASP A 28 TYR A 84 GLU A 35 ILE A 37	None	0.98A	4xjeA-3natA: undetectable	4xjeA-3natA: 22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6A93_B_8NUB3001_1 (5-HYDROXYTRYPTAMINE RECEPTOR 2A,SOLUBLE CYTOCHROME B562)	3nat	UNCHARACTERIZED PROTEIN (Enterococcus faecalis)	4 / 5	ASP A 102 ILE A 88 PHE A 71 TYR A 9	None CIT A 162 (-3.8A) None None	1.09A	6a93B-3natA: undetectable	6a93B-3natA: 19.83

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["1AQB_A_RTLA185_0","RETINOL-BINDING PROTEIN","3nat","UNCHARACTERIZED PROTEIN","Enterococcus faecalis",5,"LEU A 133;VAL A  38;MET A 143;TYR A 107;LEU A  69","None","1.45A","1aqbA-3natA:undetectable","1aqbA-3natA:25.53"],["2YVL_A_SAMA601_1","HYPOTHETICAL PROTEIN","3nat","UNCHARACTERIZED PROTEIN","Enterococcus faecalis",4,"GLU A  83;ASP A  81;ASP A  28;TYR A  72","None;CIT A 162 ( 3.3A);None; ZN A 165 ( 4.9A)","1.16A","2yvlA-3natA:0.0","2yvlA-3natA:24.60"],["4XJE_A_TOYA202_1","AADB","3nat","UNCHARACTERIZED PROTEIN","Enterococcus faecalis",4,"ASP A  28;TYR A  84;GLU A  35;ILE A  37","None","0.98A","4xjeA-3natA:undetectable","4xjeA-3natA:22.22"],["6A93_B_8NUB3001_1","5-HYDROXYTRYPTAMINE RECEPTOR 2A,SOLUBLE CYTOCHROME B562","3nat","UNCHARACTERIZED PROTEIN","Enterococcus faecalis",4,"ASP A 102;ILE A  88;PHE A  71;TYR A   9","None;CIT A 162 (-3.8A);None;None","1.09A","6a93B-3natA:undetectable","6a93B-3natA:19.83"]]