SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3nbk'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OXZ_A_0LIA1_2
(TYROSINE-PROTEIN
KINASE ABL1)		 3nbk PHOSPHOPANTETHEINE
ADENYLYLTRANSFERASE
(Mycobacterium
tuberculosis) 		5 / 9 LEU A  99
VAL A  33
ILE A  85
ARG A  50
LEU A  89
 None
 1.29A 3oxzA-3nbkA:
undetectable		 3oxzA-3nbkA:
21.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KLR_B_CHDB504_0
(FERROCHELATASE,
MITOCHONDRIAL)		 3nbk PHOSPHOPANTETHEINE
ADENYLYLTRANSFERASE
(Mycobacterium
tuberculosis) 		3 / 3 LEU A 144
PRO A 145
ARG A 155
 None
 0.69A 4klrB-3nbkA:
3.3		 4klrB-3nbkA:
22.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5SYJ_A_NIZA810_1
(CATALASE-PEROXIDASE)		 3nbk PHOSPHOPANTETHEINE
ADENYLYLTRANSFERASE
(Mycobacterium
tuberculosis) 		4 / 6 ARG A  90
LEU A 144
PRO A  12
SER A 128
 None
 1.48A 5syjA-3nbkA:
undetectable		 5syjA-3nbkA:
11.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XIW_D_LOCD503_1
(TUBULIN ALPHA-1B
CHAIN
TUBULIN BETA CHAIN)		 3nbk PHOSPHOPANTETHEINE
ADENYLYLTRANSFERASE
(Mycobacterium
tuberculosis) 		3 / 3 SER A 123
ALA A 117
VAL A 116
 None
 0.51A 5xiwC-3nbkA:
undetectable		 5xiwC-3nbkA:
17.71
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6JMJ_A_ASCA201_0
(PHOSPHOPANTETHEINE
ADENYLYLTRANSFERASE)		 3nbk PHOSPHOPANTETHEINE
ADENYLYLTRANSFERASE
(Mycobacterium
tuberculosis) 		4 / 5 GLY A   8
HIS A  17
SER A 126
SER A 127
 PNS  A 200 (-3.2A)
None
None
None
 0.34A 6jmjA-3nbkA:
24.7		 6jmjA-3nbkA:
38.04
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6JNH_A_ASCA201_0
(PHOSPHOPANTETHEINE
ADENYLYLTRANSFERASE)		 3nbk PHOSPHOPANTETHEINE
ADENYLYLTRANSFERASE
(Mycobacterium
tuberculosis) 		6 / 7 GLY A   8
PHE A  10
HIS A  17
ARG A  90
SER A 126
SER A 127
 PNS  A 200 (-3.2A)
None
None
None
None
None
 0.65A 6jnhA-3nbkA:
24.8		 6jnhA-3nbkA:
38.04
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6JOG_A_ASCA201_0
(PHOSPHOPANTETHEINE
ADENYLYLTRANSFERASE)		 3nbk PHOSPHOPANTETHEINE
ADENYLYLTRANSFERASE
(Mycobacterium
tuberculosis) 		5 / 6 GLY A   8
HIS A  17
ARG A  90
SER A 126
SER A 127
 PNS  A 200 (-3.2A)
None
None
None
None
 0.66A 6jogA-3nbkA:
24.7		 6jogA-3nbkA:
38.04