SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3nby'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FM9_A_9CRA201_2
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 3nby SNURPORTIN-1
(Homo
sapiens) 		3 / 3 GLN B  15
ILE B 108
HIS B  24
 None
 0.63A 1fm9A-3nbyB:
undetectable		 1fm9A-3nbyB:
23.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1K74_A_9CRA463_2
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 3nby SNURPORTIN-1
(Homo
sapiens) 		3 / 3 GLN B  15
ILE B 108
HIS B  24
 None
 0.62A 1k74A-3nbyB:
undetectable		 1k74A-3nbyB:
23.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2R2V_D_ACTD36_0
(GCN4 LEUCINE ZIPPER)		 3nby SNURPORTIN-1
(Homo
sapiens) 		3 / 3 SER B 266
TYR B 265
HIS B 264
 None
 0.55A 2r2vD-3nbyB:
undetectable		 2r2vD-3nbyB:
5.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LOQ_A_ACTA277_0
(UNIVERSAL STRESS
PROTEIN)		 3nby SNURPORTIN-1
(Homo
sapiens) 		3 / 3 ASP B 113
SER B 112
ARG B  44
 None
 0.88A 3loqA-3nbyB:
undetectable		 3loqA-3nbyB:
20.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N8X_B_NIMB1701_2
(PROSTAGLANDIN G/H
SYNTHASE 1)		 3nby SNURPORTIN-1
(Homo
sapiens) 		3 / 3 VAL B 281
VAL B 244
SER B 246
 None
 0.68A 3n8xB-3nbyB:
undetectable		 3n8xB-3nbyB:
20.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CSY_B_ACRB601_2
(4-ALPHA-GLUCANOTRANS
FERASE DPE1,
CHLOROPLASTIC/AMYLOP
LASTIC)		 3nby SNURPORTIN-1
(Homo
sapiens) 		4 / 5 TYR B 265
HIS B 264
LEU B  55
PRO B 194
 None
 1.43A 5csyB-3nbyB:
undetectable		 5csyB-3nbyB:
19.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z12_B_9CRB501_2
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 3nby SNURPORTIN-1
(Homo
sapiens) 		3 / 3 GLN B  15
ILE B 108
HIS B  24
 None
 0.70A 5z12B-3nbyB:
undetectable		 5z12B-3nbyB:
11.08