SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3ncc'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1S9P_A_DESA459_1
(ESTROGEN-RELATED
RECEPTOR GAMMA)		 3ncc PROLACTIN
(Homo
sapiens) 		5 / 12 LEU A  15
LEU A  18
ALA A  22
LEU A 126
ILE A 193
 None
 0.95A 1s9pA-3nccA:
undetectable		 1s9pA-3nccA:
22.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1S9P_C_DESC500_1
(ESTROGEN-RELATED
RECEPTOR GAMMA)		 3ncc PROLACTIN
(Homo
sapiens) 		5 / 12 LEU A  15
LEU A  18
ALA A  22
LEU A 126
ILE A 193
 None
 1.05A 1s9pC-3nccA:
undetectable		 1s9pC-3nccA:
22.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1S9P_D_DESD600_1
(ESTROGEN-RELATED
RECEPTOR GAMMA)		 3ncc PROLACTIN
(Homo
sapiens) 		5 / 12 LEU A  15
LEU A  18
ALA A  22
LEU A 126
ILE A 193
 None
 1.12A 1s9pD-3nccA:
undetectable		 1s9pD-3nccA:
22.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YA3_A_STRA1001_2
(MINERALOCORTICOID
RECEPTOR)		 3ncc PROLACTIN
(Homo
sapiens) 		4 / 4 LEU A 127
LEU A  25
SER A  26
LEU A 186
 None
 1.12A 1ya3A-3nccA:
undetectable		 1ya3A-3nccA:
24.31