SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3ncv'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Q23_B_FUAB703_2
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 3ncv DNA MISMATCH REPAIR
PROTEIN MUTL
(Neisseria
gonorrhoeae) 		3 / 3 VAL A 499
ALA A 496
HIS A 493
 None
 0.71A 1q23C-3ncvA:
undetectable		 1q23C-3ncvA:
20.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Q23_C_FUAC701_1
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 3ncv DNA MISMATCH REPAIR
PROTEIN MUTL
(Neisseria
gonorrhoeae) 		4 / 4 ALA A 495
VAL A 499
ALA A 496
HIS A 493
 None
 0.83A 1q23A-3ncvA:
undetectable		 1q23A-3ncvA:
20.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Q23_E_FUAE706_2
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 3ncv DNA MISMATCH REPAIR
PROTEIN MUTL
(Neisseria
gonorrhoeae) 		4 / 4 ALA A 495
VAL A 499
ALA A 496
HIS A 493
 None
 0.80A 1q23F-3ncvA:
undetectable		 1q23F-3ncvA:
20.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Q23_G_FUAG708_2
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 3ncv DNA MISMATCH REPAIR
PROTEIN MUTL
(Neisseria
gonorrhoeae) 		3 / 3 VAL A 499
ALA A 496
HIS A 493
 None
 0.72A 1q23H-3ncvA:
undetectable		 1q23H-3ncvA:
20.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Q23_I_FUAI707_1
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 3ncv DNA MISMATCH REPAIR
PROTEIN MUTL
(Neisseria
gonorrhoeae) 		3 / 3 VAL A 499
ALA A 496
HIS A 493
 None
 0.76A 1q23G-3ncvA:
undetectable		 1q23G-3ncvA:
20.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Q23_J_FUAJ711_2
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 3ncv DNA MISMATCH REPAIR
PROTEIN MUTL
(Neisseria
gonorrhoeae) 		4 / 4 ALA A 495
VAL A 499
ALA A 496
HIS A 493
 None
 0.83A 1q23K-3ncvA:
undetectable		 1q23K-3ncvA:
20.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Q23_K_FUAK712_2
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 3ncv DNA MISMATCH REPAIR
PROTEIN MUTL
(Neisseria
gonorrhoeae) 		3 / 3 VAL A 499
ALA A 496
HIS A 493
 None
 0.73A 1q23L-3ncvA:
undetectable		 1q23L-3ncvA:
20.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OGY_A_C2FA3000_0
(5-METHYLTETRAHYDROFO
LATE CORRINOID/IRON
SULFUR PROTEIN
METHYLTRANSFERASE)		 3ncv DNA MISMATCH REPAIR
PROTEIN MUTL
(Neisseria
gonorrhoeae) 		5 / 12 ILE A 598
LEU A 599
GLY A 546
SER A 516
GLN A 515
 None
 1.27A 2ogyA-3ncvA:
undetectable		 2ogyA-3ncvA:
23.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABK_W_CHDW1059_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 1)		 3ncv DNA MISMATCH REPAIR
PROTEIN MUTL
(Neisseria
gonorrhoeae) 		4 / 5 ILE A 608
ARG A 498
MET A 626
THR A 629
 None
 1.41A 3abkN-3ncvA:
undetectable
3abkW-3ncvA:
undetectable		 3abkN-3ncvA:
17.43
3abkW-3ncvA:
16.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DQF_A_CZEA613_1
(SERUM ALBUMIN)		 3ncv DNA MISMATCH REPAIR
PROTEIN MUTL
(Neisseria
gonorrhoeae) 		5 / 9 ALA A 575
LEU A 582
GLY A 580
LEU A 579
LEU A 549
 None
 1.05A 5dqfA-3ncvA:
undetectable		 5dqfA-3ncvA:
16.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5U4S_A_BEZA301_0
(PUTATIVE SHORT CHAIN
DEHYDROGENASE)		 3ncv DNA MISMATCH REPAIR
PROTEIN MUTL
(Neisseria
gonorrhoeae) 		4 / 7 ILE A 608
LEU A 622
MET A 626
LEU A 623
 None
 1.01A 5u4sA-3ncvA:
undetectable		 5u4sA-3ncvA:
22.75