SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3ncy'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1D4Y_A_TPVA501_2
(PROTEIN (HIV-1
PROTEASE))		 3ncy ADIC
(Salmonella
enterica) 		4 / 8 ALA A 235
GLY A 230
ILE A 229
ILE A  23
 None
 0.70A 1d4yB-3ncyA:
undetectable		 1d4yB-3ncyA:
12.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FML_B_RTLB501_0
(RETINOL DEHYDRATASE)		 3ncy ADIC
(Salmonella
enterica) 		5 / 12 ILE A 420
TYR A 424
LEU A  85
LEU A  92
TYR A 367
 None
 1.12A 1fmlB-3ncyA:
undetectable		 1fmlB-3ncyA:
21.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RLB_F_REAF177_1
(RETINOL BINDING
PROTEIN)		 3ncy ADIC
(Salmonella
enterica) 		5 / 11 PHE A 360
LEU A  92
ALA A 422
VAL A 363
LEU A 366
 None
 1.18A 1rlbF-3ncyA:
undetectable		 1rlbF-3ncyA:
16.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RUK_H_BEZH601_0
(IMMUNOGLOBULIN
IGG2A, HEAVY CHAIN
IMMUNOGLOBULIN
IGG2A, LIGHT CHAIN)		 3ncy ADIC
(Salmonella
enterica) 		4 / 8 ASN A 101
LEU A 290
GLY A 288
GLY A  25
 None
 0.81A 1rukH-3ncyA:
undetectable
1rukL-3ncyA:
undetectable		 1rukH-3ncyA:
20.22
1rukL-3ncyA:
17.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z95_A_198A501_2
(ANDROGEN RECEPTOR)		 3ncy ADIC
(Salmonella
enterica) 		4 / 6 LEU A 197
ASN A 198
LEU A 362
ILE A 359
 None
 0.99A 1z95A-3ncyA:
undetectable		 1z95A-3ncyA:
19.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A3A_A_TEPA1434_1
(CHITINASE)		 3ncy ADIC
(Salmonella
enterica) 		3 / 3 TRP A 202
THR A 361
TYR A 365
 None
 1.16A 2a3aA-3ncyA:
undetectable		 2a3aA-3ncyA:
24.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A3A_B_TEPB2434_1
(CHITINASE)		 3ncy ADIC
(Salmonella
enterica) 		3 / 3 TRP A 202
THR A 361
TYR A 365
 None
 1.18A 2a3aB-3ncyA:
undetectable		 2a3aB-3ncyA:
24.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A3B_A_CFFA1434_1
(CHITINASE)		 3ncy ADIC
(Salmonella
enterica) 		3 / 3 TRP A 202
THR A 361
TYR A 365
 None
 1.15A 2a3bA-3ncyA:
undetectable		 2a3bA-3ncyA:
24.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2IGT_B_SAMB1002_0
(SAM DEPENDENT
METHYLTRANSFERASE)		 3ncy ADIC
(Salmonella
enterica) 		5 / 12 ALA A  77
ALA A 370
ALA A  75
GLY A  82
GLY A  86
 None
 1.14A 2igtB-3ncyA:
undetectable		 2igtB-3ncyA:
23.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YS6_A_GLYA431_0
(PHOSPHORIBOSYLGLYCIN
AMIDE SYNTHETASE)		 3ncy ADIC
(Salmonella
enterica) 		4 / 8 TYR A  74
ASN A  90
GLY A  86
PRO A  83
 None
 0.81A 2ys6A-3ncyA:
undetectable		 2ys6A-3ncyA:
24.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ELZ_C_CHDC150_0
(ILEAL BILE
ACID-BINDING PROTEIN)		 3ncy ADIC
(Salmonella
enterica) 		5 / 12 ASN A  34
THR A  38
VAL A 240
ILE A  43
THR A  49
 None
 1.42A 3elzC-3ncyA:
undetectable		 3elzC-3ncyA:
15.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OCT_A_1N1A663_2
(TYROSINE-PROTEIN
KINASE BTK)		 3ncy ADIC
(Salmonella
enterica) 		4 / 5 PHE A  29
ILE A 246
ASN A 198
PHE A 262
 None
 1.35A 3octA-3ncyA:
undetectable		 3octA-3ncyA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OXX_C_DR7C100_2
(HIV-1 PROTEASE)		 3ncy ADIC
(Salmonella
enterica) 		5 / 11 ALA A 304
ASP A 307
GLY A  72
VAL A 212
PRO A 364
 None
 1.00A 3oxxD-3ncyA:
undetectable		 3oxxD-3ncyA:
12.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SUD_D_SUED1201_1
(NS3 PROTEASE, NS4A
PROTEIN)		 3ncy ADIC
(Salmonella
enterica) 		5 / 12 GLY A 175
ALA A 254
ALA A  36
ALA A  37
SER A 195
 None
 1.02A 3sudD-3ncyA:
undetectable		 3sudD-3ncyA:
18.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TL9_A_ROCA401_4
(PROTEASE)		 3ncy ADIC
(Salmonella
enterica) 		4 / 4 ASP A 306
ASP A 307
GLY A  71
THR A  89
 None
 1.28A 3tl9B-3ncyA:
undetectable		 3tl9B-3ncyA:
12.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4BLV_B_SAMB1281_0
(RIBOSOMAL RNA LARGE
SUBUNIT
METHYLTRANSFERASE J)		 3ncy ADIC
(Salmonella
enterica) 		5 / 12 ASP A  67
GLY A  71
SER A  69
LEU A 374
GLY A 376
 None
 1.23A 4blvB-3ncyA:
undetectable		 4blvB-3ncyA:
19.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DR6_A_SRYA1956_1
(16S RRNA
30S RIBOSOMAL
PROTEIN S12)		 3ncy ADIC
(Salmonella
enterica) 		3 / 3 LYS A 145
PRO A 144
LYS A 218
 None
 1.41A 4dr6L-3ncyA:
undetectable		 4dr6L-3ncyA:
15.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KUK_A_RBFA201_2
(BLUE-LIGHT
PHOTORECEPTOR)		 3ncy ADIC
(Salmonella
enterica) 		5 / 9 LEU A 388
VAL A  59
LEU A  66
ILE A 390
GLY A 381
 None
 1.11A 4kukA-3ncyA:
undetectable		 4kukA-3ncyA:
14.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OKW_A_198A1001_2
(ANDROGEN RECEPTOR)		 3ncy ADIC
(Salmonella
enterica) 		4 / 7 LEU A 197
ASN A 198
LEU A 362
ILE A 359
 None
 1.04A 4okwA-3ncyA:
undetectable		 4okwA-3ncyA:
18.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OLT_A_GCSA301_1
(CHITOSANASE)		 3ncy ADIC
(Salmonella
enterica) 		4 / 4 ASP A 307
GLY A  71
PRO A  70
GLN A 299
 None
 1.25A 4oltA-3ncyA:
undetectable		 4oltA-3ncyA:
20.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVQ_K_BO2K301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 3ncy ADIC
(Salmonella
enterica) 		5 / 9 ALA A 210
ALA A 213
ILE A 229
GLY A 231
ALA A 227
 None
 1.05A 4qvqK-3ncyA:
undetectable
4qvqL-3ncyA:
undetectable		 4qvqK-3ncyA:
20.14
4qvqL-3ncyA:
19.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVQ_Y_BO2Y301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 3ncy ADIC
(Salmonella
enterica) 		5 / 9 ALA A 210
ALA A 213
ILE A 229
GLY A 231
ALA A 227
 None
 1.05A 4qvqY-3ncyA:
undetectable
4qvqZ-3ncyA:
undetectable		 4qvqY-3ncyA:
20.14
4qvqZ-3ncyA:
19.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZE0_A_VORA602_1
(LANOSTEROL 14-ALPHA
DEMETHYLASE)		 3ncy ADIC
(Salmonella
enterica) 		5 / 9 THR A 228
ILE A 229
THR A 391
LEU A 372
LEU A  66
 None
 1.34A 4ze0A-3ncyA:
undetectable		 4ze0A-3ncyA:
21.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FA8_A_SAMA301_0
(RIBOSOMAL PROTEIN
L11
METHYLTRANSFERASE,
PUTATIVE)		 3ncy ADIC
(Salmonella
enterica) 		5 / 12 PRO A  14
GLY A 231
ILE A 226
ILE A  23
ASN A  22
 None
 1.08A 5fa8A-3ncyA:
undetectable		 5fa8A-3ncyA:
16.63
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5J4N_A_AG2A501_1
(ARGININE/AGMATINE
ANTIPORTER)		 3ncy ADIC
(Salmonella
enterica) 		5 / 6 GLY A 100
ASN A 101
MET A 104
ILE A 205
TRP A 293
 None
 0.70A 5j4nA-3ncyA:
56.6		 5j4nA-3ncyA:
94.16
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5J4N_B_AG2B501_1
(ARGININE/AGMATINE
ANTIPORTER)		 3ncy ADIC
(Salmonella
enterica) 		6 / 6 ILE A  23
GLY A 100
ASN A 101
MET A 104
ILE A 205
TRP A 293
 None
 0.65A 5j4nB-3ncyA:
56.8		 5j4nB-3ncyA:
94.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L5F_Y_BO2Y301_1
(PROTEASOME SUBUNIT
BETA
TYPE-8,PROTEASOME
SUBUNIT BETA TYPE-5
PROTEASOME SUBUNIT
BETA
TYPE-6,PROTEASOME
SUBUNIT BETA
TYPE-1,PROTEASOME
SUBUNIT BETA
TYPE-6,PROTEASOME
SUBUNIT BETA
TYPE-1,PROTEASOME
SUBUNIT BETA TYPE-6)		 3ncy ADIC
(Salmonella
enterica) 		4 / 8 THR A  89
ALA A  75
ASP A  67
SER A  69
 None
 1.09A 5l5fY-3ncyA:
undetectable
5l5fZ-3ncyA:
undetectable		 5l5fY-3ncyA:
17.50
5l5fZ-3ncyA:
19.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L66_K_BO2K301_1
(PROTEASOME SUBUNIT
BETA
TYPE-8,PROTEASOME
SUBUNIT BETA TYPE-5
PROTEASOME SUBUNIT
BETA
TYPE-6,PROTEASOME
SUBUNIT BETA
TYPE-1,PROTEASOME
SUBUNIT BETA
TYPE-6,PROTEASOME
SUBUNIT BETA
TYPE-1,PROTEASOME
SUBUNIT BETA TYPE-6)		 3ncy ADIC
(Salmonella
enterica) 		5 / 10 THR A  89
THR A 368
ALA A  75
ASP A  67
SER A  69
 None
 1.42A 5l66K-3ncyA:
undetectable
5l66L-3ncyA:
undetectable		 5l66K-3ncyA:
18.52
5l66L-3ncyA:
19.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L66_Y_BO2Y301_1
(PROTEASOME SUBUNIT
BETA
TYPE-8,PROTEASOME
SUBUNIT BETA TYPE-5
PROTEASOME SUBUNIT
BETA
TYPE-6,PROTEASOME
SUBUNIT BETA
TYPE-1,PROTEASOME
SUBUNIT BETA
TYPE-6,PROTEASOME
SUBUNIT BETA
TYPE-1,PROTEASOME
SUBUNIT BETA TYPE-6)		 3ncy ADIC
(Salmonella
enterica) 		5 / 10 THR A  89
THR A 368
ALA A  75
ASP A  67
SER A  69
 None
 1.42A 5l66Y-3ncyA:
undetectable
5l66Z-3ncyA:
undetectable		 5l66Y-3ncyA:
18.52
5l66Z-3ncyA:
19.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5SXQ_A_NIZA808_1
(CATALASE-PEROXIDASE)		 3ncy ADIC
(Salmonella
enterica) 		4 / 8 VAL A 217
GLN A 299
LEU A 296
THR A 300
 None
 0.99A 5sxqA-3ncyA:
0.5		 5sxqA-3ncyA:
22.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5SXT_A_NIZA807_1
(CATALASE-PEROXIDASE)		 3ncy ADIC
(Salmonella
enterica) 		4 / 8 VAL A 217
GLN A 299
LEU A 296
THR A 300
 None
 0.98A 5sxtA-3ncyA:
undetectable		 5sxtA-3ncyA:
22.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5SXT_B_NIZB808_1
(CATALASE-PEROXIDASE)		 3ncy ADIC
(Salmonella
enterica) 		4 / 8 VAL A 217
GLN A 299
LEU A 296
THR A 300
 None
 0.97A 5sxtB-3ncyA:
undetectable		 5sxtB-3ncyA:
22.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5YF0_A_SAMA505_0
(CARNOSINE
N-METHYLTRANSFERASE)		 3ncy ADIC
(Salmonella
enterica) 		5 / 12 GLY A 206
ASN A  22
THR A 361
TYR A  93
TYR A 397
 None
 1.19A 5yf0A-3ncyA:
undetectable		 5yf0A-3ncyA:
21.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5YF0_B_SAMB503_0
(CARNOSINE
N-METHYLTRANSFERASE)		 3ncy ADIC
(Salmonella
enterica) 		5 / 12 GLY A 206
ASN A  22
THR A 361
TYR A  93
TYR A 397
 None
 1.18A 5yf0B-3ncyA:
0.0		 5yf0B-3ncyA:
21.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AJI_A_AY6A1001_0
(DRUG EXPORTERS OF
THE RND
SUPERFAMILY-LIKE
PROTEIN,ENDOLYSIN)		 3ncy ADIC
(Salmonella
enterica) 		5 / 12 VAL A  28
ILE A 246
ILE A 162
LEU A  35
ALA A  33
 None
 1.20A 6ajiA-3ncyA:
undetectable		 6ajiA-3ncyA:
20.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6C2M_B_SUEB1202_1
(NS3 PROTEASE)		 3ncy ADIC
(Salmonella
enterica) 		5 / 9 VAL A 207
LEU A 201
ALA A 401
VAL A 402
SER A 405
 None
 1.35A 6c2mB-3ncyA:
undetectable		 6c2mB-3ncyA:
10.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HUP_B_DZPB502_0
(GAMMA-AMINOBUTYRIC
ACID RECEPTOR
SUBUNIT
ALPHA-1,GAMMA-AMINOB
UTYRIC ACID RECEPTOR
SUBUNIT ALPHA-1
GAMMA-AMINOBUTYRIC
ACID RECEPTOR
SUBUNIT BETA-3)		 3ncy ADIC
(Salmonella
enterica) 		5 / 11 ILE A 359
LEU A 362
THR A 368
THR A  89
LEU A 417
 None
 1.43A 6hupA-3ncyA:
undetectable
6hupB-3ncyA:
1.8		 6hupA-3ncyA:
10.11
6hupB-3ncyA:
11.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NKN_W_CHDW101_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 3ncy ADIC
(Salmonella
enterica) 		3 / 3 ARG A 384
LEU A 388
PHE A 392
 None
 0.61A 6nknP-3ncyA:
2.3		 6nknP-3ncyA:
20.93