SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3nd0'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FE2_A_LAXA700_2
(PROSTAGLANDIN
ENDOPEROXIDE H
SYNTHASE-1)		 3nd0 SLL0855 PROTEIN
(Synechocystis
sp.
PCC
6803) 		5 / 12 LEU A 290
GLY A 138
ALA A 137
SER A 134
GLY A 131
 None
 0.94A 1fe2A-3nd0A:
undetectable		 1fe2A-3nd0A:
23.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1IGX_A_EPAA700_1
(PROSTAGLANDIN
ENDOPEROXIDE H
SYNTHASE-1)		 3nd0 SLL0855 PROTEIN
(Synechocystis
sp.
PCC
6803) 		5 / 12 LEU A 290
GLY A 138
ALA A 137
SER A 134
GLY A 131
 None
 0.93A 1igxA-3nd0A:
undetectable		 1igxA-3nd0A:
23.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MX1_D_THAD4_1
(LIVER
CARBOXYLESTERASE I)		 3nd0 SLL0855 PROTEIN
(Synechocystis
sp.
PCC
6803) 		6 / 12 LEU A  92
GLY A 130
GLY A 131
VAL A  53
LEU A 135
LEU A  88
 None
 1.45A 1mx1D-3nd0A:
undetectable		 1mx1D-3nd0A:
20.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1WSV_B_THHB4001_0
(AMINOMETHYLTRANSFERA
SE)		 3nd0 SLL0855 PROTEIN
(Synechocystis
sp.
PCC
6803) 		5 / 12 THR A 324
LEU A 325
ILE A 326
CYH A 330
TRP A 314
 None
 1.33A 1wsvB-3nd0A:
undetectable		 1wsvB-3nd0A:
23.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BDM_A_TMIA501_1
(CYTOCHROME P450 2B4)		 3nd0 SLL0855 PROTEIN
(Synechocystis
sp.
PCC
6803) 		4 / 7 MET A 407
LEU A 402
GLY A 191
ILE A 105
 None
 1.08A 2bdmA-3nd0A:
undetectable		 2bdmA-3nd0A:
23.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FXD_A_DR7A102_1
(POL PROTEIN)		 3nd0 SLL0855 PROTEIN
(Synechocystis
sp.
PCC
6803) 		5 / 11 LEU A 290
GLY A 138
ALA A 137
GLY A 131
PHE A  90
 None
 1.07A 2fxdA-3nd0A:
undetectable		 2fxdA-3nd0A:
15.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HS2_A_017A201_2
(PROTEASE)		 3nd0 SLL0855 PROTEIN
(Synechocystis
sp.
PCC
6803) 		5 / 12 ARG A 170
LEU A 112
GLY A 176
ALA A 177
ILE A 108
 None
 1.05A 2hs2B-3nd0A:
undetectable		 2hs2B-3nd0A:
15.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NPN_A_SAMA4633_0
(PUTATIVE COBALAMIN
SYNTHESIS RELATED
PROTEIN)		 3nd0 SLL0855 PROTEIN
(Synechocystis
sp.
PCC
6803) 		5 / 9 THR A 147
GLY A 180
THR A 183
ALA A 184
LEU A 403
 None
 1.31A 2npnA-3nd0A:
undetectable		 2npnA-3nd0A:
19.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VXA_G_RBFG200_1
(DODECIN)		 3nd0 SLL0855 PROTEIN
(Synechocystis
sp.
PCC
6803) 		4 / 8 HIS A  28
GLN A 206
ARG A  30
THR A 158
 None
 1.32A 2vxaF-3nd0A:
undetectable
2vxaG-3nd0A:
undetectable
2vxaI-3nd0A:
undetectable		 2vxaF-3nd0A:
10.86
2vxaG-3nd0A:
10.86
2vxaI-3nd0A:
10.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YVL_C_SAMC604_0
(HYPOTHETICAL PROTEIN)		 3nd0 SLL0855 PROTEIN
(Synechocystis
sp.
PCC
6803) 		5 / 12 ILE A 296
GLY A 291
SER A 292
ALA A  79
ALA A 344
 None
 1.26A 2yvlC-3nd0A:
undetectable		 2yvlC-3nd0A:
18.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AXZ_A_ADNA401_1
(TRNA
(GUANINE-N(1)-)-METH
YLTRANSFERASE)		 3nd0 SLL0855 PROTEIN
(Synechocystis
sp.
PCC
6803) 		5 / 12 GLY A 176
GLY A 152
LEU A 181
GLY A 180
GLY A 178
 None
 0.93A 3axzA-3nd0A:
undetectable		 3axzA-3nd0A:
21.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CKK_A_SAMA301_0
(TRNA
(GUANINE-N(7)-)-METH
YLTRANSFERASE)		 3nd0 SLL0855 PROTEIN
(Synechocystis
sp.
PCC
6803) 		5 / 12 GLY A 145
GLY A 104
ILE A 345
ALA A 141
LEU A 181
 CL  A 467 ( 4.8A)
None
None
None
None
 1.09A 3ckkA-3nd0A:
undetectable		 3ckkA-3nd0A:
19.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EM0_B_CHDB150_0
(ILEAL BILE
ACID-BINDING PROTEIN)		 3nd0 SLL0855 PROTEIN
(Synechocystis
sp.
PCC
6803) 		5 / 12 MET A 352
THR A 336
PHE A 264
VAL A 394
ILE A 436
 None
 1.20A 3em0B-3nd0A:
undetectable		 3em0B-3nd0A:
15.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FRQ_A_ERYA195_0
(REPRESSOR PROTEIN
MPHR(A))		 3nd0 SLL0855 PROTEIN
(Synechocystis
sp.
PCC
6803) 		5 / 12 THR A 393
SER A 357
MET A 386
ILE A 234
THR A 408
 None
 1.06A 3frqA-3nd0A:
undetectable		 3frqA-3nd0A:
17.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IJX_B_HCZB800_1
(GLUTAMATE RECEPTOR 2)		 3nd0 SLL0855 PROTEIN
(Synechocystis
sp.
PCC
6803) 		5 / 10 SER A 134
LEU A 297
SER A 298
ILE A 293
GLY A 291
 None
 1.38A 3ijxB-3nd0A:
undetectable
3ijxD-3nd0A:
undetectable		 3ijxB-3nd0A:
17.20
3ijxD-3nd0A:
17.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IK6_B_HCZB262_1
(GLUTAMATE RECEPTOR 2)		 3nd0 SLL0855 PROTEIN
(Synechocystis
sp.
PCC
6803) 		5 / 10 ILE A 293
GLY A 291
SER A 134
LEU A 297
SER A 298
 None
 1.32A 3ik6B-3nd0A:
undetectable
3ik6E-3nd0A:
undetectable		 3ik6B-3nd0A:
17.20
3ik6E-3nd0A:
17.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ILU_B_HFZB800_1
(GLUTAMATE RECEPTOR 2)		 3nd0 SLL0855 PROTEIN
(Synechocystis
sp.
PCC
6803) 		5 / 10 SER A 134
LEU A 297
SER A 298
ILE A 293
GLY A 291
 None
 1.31A 3iluB-3nd0A:
undetectable
3iluE-3nd0A:
undetectable		 3iluB-3nd0A:
17.20
3iluE-3nd0A:
17.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ILU_E_HFZE800_1
(GLUTAMATE RECEPTOR 2)		 3nd0 SLL0855 PROTEIN
(Synechocystis
sp.
PCC
6803) 		5 / 11 ILE A 293
GLY A 291
SER A 134
LEU A 297
SER A 298
 None
 1.32A 3iluB-3nd0A:
undetectable
3iluE-3nd0A:
undetectable		 3iluB-3nd0A:
17.20
3iluE-3nd0A:
17.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3L4D_A_TPFA490_1
(STEROL 14-ALPHA
DEMETHYLASE)		 3nd0 SLL0855 PROTEIN
(Synechocystis
sp.
PCC
6803) 		4 / 8 ALA A 396
ALA A 400
THR A 404
LEU A 353
 None
 0.94A 3l4dA-3nd0A:
undetectable		 3l4dA-3nd0A:
20.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3L4D_D_TPFD490_1
(STEROL 14-ALPHA
DEMETHYLASE)		 3nd0 SLL0855 PROTEIN
(Synechocystis
sp.
PCC
6803) 		4 / 8 ALA A 396
ALA A 400
THR A 404
LEU A 353
 None
 0.93A 3l4dD-3nd0A:
undetectable		 3l4dD-3nd0A:
20.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MDR_B_GJZB506_1
(CHOLESTEROL
24-HYDROXYLASE)		 3nd0 SLL0855 PROTEIN
(Synechocystis
sp.
PCC
6803) 		4 / 6 ILE A 148
THR A  42
ALA A 220
THR A 183
 None
 1.02A 3mdrB-3nd0A:
undetectable		 3mdrB-3nd0A:
24.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MWS_B_017B201_1
(HIV-1 PROTEASE)		 3nd0 SLL0855 PROTEIN
(Synechocystis
sp.
PCC
6803) 		5 / 12 ARG A 170
LEU A 112
GLY A 176
ALA A 177
ILE A 108
 None
 1.03A 3mwsA-3nd0A:
undetectable		 3mwsA-3nd0A:
15.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MWS_B_017B201_2
(HIV-1 PROTEASE)		 3nd0 SLL0855 PROTEIN
(Synechocystis
sp.
PCC
6803) 		5 / 12 LEU A  92
ALA A  97
ASP A  99
VAL A 129
ILE A 126
 None
 1.15A 3mwsB-3nd0A:
undetectable		 3mwsB-3nd0A:
15.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NU3_B_478B401_1
(PROTEASE)		 3nd0 SLL0855 PROTEIN
(Synechocystis
sp.
PCC
6803) 		5 / 12 ARG A 170
LEU A 112
GLY A 176
ALA A 177
ILE A 108
 None
 1.02A 3nu3A-3nd0A:
undetectable		 3nu3A-3nd0A:
15.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NU5_B_478B401_2
(PROTEASE)		 3nd0 SLL0855 PROTEIN
(Synechocystis
sp.
PCC
6803) 		5 / 12 ARG A 170
LEU A 112
GLY A 176
ALA A 177
ILE A 108
 None
 1.01A 3nu5B-3nd0A:
undetectable		 3nu5B-3nd0A:
14.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P2K_B_SAMB6735_0
(16S RRNA METHYLASE)		 3nd0 SLL0855 PROTEIN
(Synechocystis
sp.
PCC
6803) 		5 / 12 GLY A 110
GLY A 114
GLU A 198
THR A 438
LEU A 441
 None
 1.08A 3p2kB-3nd0A:
undetectable		 3p2kB-3nd0A:
18.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PWM_B_017B402_1
(PROTEASE)		 3nd0 SLL0855 PROTEIN
(Synechocystis
sp.
PCC
6803) 		5 / 12 ARG A 170
LEU A 112
GLY A 176
ALA A 177
ILE A 108
 None
 1.04A 3pwmA-3nd0A:
undetectable		 3pwmA-3nd0A:
15.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VYW_A_SAMA501_0
(MNMC2)		 3nd0 SLL0855 PROTEIN
(Synechocystis
sp.
PCC
6803) 		5 / 12 TYR A 437
TYR A 340
GLY A 142
GLY A 346
ALA A 184
 None
 1.09A 3vywA-3nd0A:
undetectable		 3vywA-3nd0A:
21.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VYW_D_SAMD401_0
(MNMC2)		 3nd0 SLL0855 PROTEIN
(Synechocystis
sp.
PCC
6803) 		5 / 12 TYR A 437
TYR A 340
GLY A 142
GLY A 346
ALA A 184
 None
 1.12A 3vywD-3nd0A:
undetectable		 3vywD-3nd0A:
21.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WSJ_A_MK1A201_2
(PROTEASE)		 3nd0 SLL0855 PROTEIN
(Synechocystis
sp.
PCC
6803) 		4 / 7 ARG A 170
LEU A 112
ALA A 177
ILE A 108
 None
 0.85A 3wsjB-3nd0A:
undetectable		 3wsjB-3nd0A:
12.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DT8_B_ADNB401_1
(APH(2'')-ID)		 3nd0 SLL0855 PROTEIN
(Synechocystis
sp.
PCC
6803) 		5 / 10 GLY A 151
ILE A 108
PRO A 201
LEU A 194
ILE A 195
 None
 1.10A 4dt8B-3nd0A:
undetectable		 4dt8B-3nd0A:
20.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HXY_B_ACAB502_1
(PLM1)		 3nd0 SLL0855 PROTEIN
(Synechocystis
sp.
PCC
6803) 		4 / 7 VAL A 394
SER A 103
TYR A 437
LEU A 194
 None
CL  A 467 (-2.7A)
None
None
 1.18A 4hxyB-3nd0A:
undetectable		 4hxyB-3nd0A:
25.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JEC_B_478B401_2
(HIV-1 PROTEASE)		 3nd0 SLL0855 PROTEIN
(Synechocystis
sp.
PCC
6803) 		5 / 12 ARG A 170
LEU A 112
GLY A 176
ALA A 177
ILE A 108
 None
 1.02A 4jecB-3nd0A:
undetectable		 4jecB-3nd0A:
15.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JLT_A_8PRA505_1
(CYTOCHROME P450 2B4)		 3nd0 SLL0855 PROTEIN
(Synechocystis
sp.
PCC
6803) 		4 / 8 ILE A 375
ALA A 384
VAL A 242
PRO A 243
 None
 0.82A 4jltA-3nd0A:
undetectable		 4jltA-3nd0A:
23.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KT0_A_PQNA2001_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1
PHOTOSYSTEM I
REACTION CENTER
SUBUNIT IX)		 3nd0 SLL0855 PROTEIN
(Synechocystis
sp.
PCC
6803) 		5 / 11 GLY A  43
ALA A 182
GLY A 151
ILE A 436
LEU A 268
 None
 1.11A 4kt0A-3nd0A:
undetectable
4kt0J-3nd0A:
undetectable		 4kt0A-3nd0A:
23.64
4kt0J-3nd0A:
6.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PD9_A_ADNA501_2
(NUPC FAMILY PROTEIN)		 3nd0 SLL0855 PROTEIN
(Synechocystis
sp.
PCC
6803) 		3 / 3 THR A 324
ASN A 317
PHE A 316
 None
 0.81A 4pd9A-3nd0A:
undetectable		 4pd9A-3nd0A:
25.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PTH_A_FOLA201_1
(DIHYDROFOLATE
REDUCTASE)		 3nd0 SLL0855 PROTEIN
(Synechocystis
sp.
PCC
6803) 		3 / 3 ASP A 273
LEU A 272
PHE A 269
 None
 0.71A 4pthA-3nd0A:
undetectable		 4pthA-3nd0A:
15.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R29_A_SAMA301_0
(UNCHARACTERIZED
PROTEIN)		 3nd0 SLL0855 PROTEIN
(Synechocystis
sp.
PCC
6803) 		5 / 12 SER A 103
GLY A 145
GLN A 149
ALA A 174
GLY A 178
 CL  A 467 (-2.7A)
CL  A 467 ( 4.8A)
None
None
None
 1.29A 4r29A-3nd0A:
undetectable		 4r29A-3nd0A:
17.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YDQ_B_HFGB802_0
(PROLINE--TRNA LIGASE)		 3nd0 SLL0855 PROTEIN
(Synechocystis
sp.
PCC
6803) 		5 / 12 PHE A 300
VAL A 328
THR A 305
SER A  82
GLY A 291
 None
 1.01A 4ydqB-3nd0A:
undetectable		 4ydqB-3nd0A:
21.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YPM_A_BO2A801_1
(LON PROTEASE)		 3nd0 SLL0855 PROTEIN
(Synechocystis
sp.
PCC
6803) 		5 / 12 ALA A 141
LEU A 135
THR A 147
GLY A 102
ALA A 344
 None
 1.07A 4ypmA-3nd0A:
undetectable		 4ypmA-3nd0A:
20.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZE0_A_VORA602_1
(LANOSTEROL 14-ALPHA
DEMETHYLASE)		 3nd0 SLL0855 PROTEIN
(Synechocystis
sp.
PCC
6803) 		5 / 9 THR A 147
ILE A 148
GLY A 191
LEU A 403
LEU A 353
 None
 1.43A 4ze0A-3nd0A:
0.3		 4ze0A-3nd0A:
22.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CDP_H_EVPH2101_1
(DNA GYRASE SUBUNIT A
DNA GYRASE SUBUNIT B)		 3nd0 SLL0855 PROTEIN
(Synechocystis
sp.
PCC
6803) 		4 / 6 SER A 342
GLY A 307
ASP A 306
GLY A 142
 None
 0.92A 5cdpA-3nd0A:
undetectable
5cdpB-3nd0A:
undetectable		 5cdpA-3nd0A:
22.95
5cdpB-3nd0A:
17.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HHJ_A_GLYA403_0
(RETRON-TYPE REVERSE
TRANSCRIPTASE)		 3nd0 SLL0855 PROTEIN
(Synechocystis
sp.
PCC
6803) 		4 / 4 LEU A 445
LEU A 116
GLY A 110
GLU A 113
 None
 1.12A 5hhjA-3nd0A:
undetectable		 5hhjA-3nd0A:
22.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N0X_A_SAMA501_0
(PEPTIDE
N-METHYLTRANSFERASE)		 3nd0 SLL0855 PROTEIN
(Synechocystis
sp.
PCC
6803) 		5 / 12 GLY A 151
PHE A  49
ILE A 223
ALA A 220
VAL A  44
 None
 1.13A 5n0xA-3nd0A:
undetectable		 5n0xA-3nd0A:
20.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VIM_B_SAMB301_0
(METHYLTRANSFERASE)		 3nd0 SLL0855 PROTEIN
(Synechocystis
sp.
PCC
6803) 		5 / 12 GLY A 295
GLY A 291
GLY A  84
PHE A 300
ILE A 296
 None
 0.95A 5vimB-3nd0A:
undetectable		 5vimB-3nd0A:
19.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Y2T_A_8LXA501_0
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 3nd0 SLL0855 PROTEIN
(Synechocystis
sp.
PCC
6803) 		5 / 12 LEU A 272
GLY A 102
GLN A 149
ILE A 348
LEU A 118
 None
None
None
CL  A 467 (-4.6A)
None
 1.24A 5y2tA-3nd0A:
undetectable		 5y2tA-3nd0A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DH3_A_017A101_1
(PROTEASE)		 3nd0 SLL0855 PROTEIN
(Synechocystis
sp.
PCC
6803) 		5 / 12 ARG A 170
LEU A 112
GLY A 176
ALA A 177
ILE A 108
 None
 1.04A 6dh3B-3nd0A:
undetectable		 6dh3B-3nd0A:
11.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EBP_D_DAHD123_0
(RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE,
BETA SUBUNIT)		 3nd0 SLL0855 PROTEIN
(Synechocystis
sp.
PCC
6803) 		5 / 10 THR A 399
GLY A 196
ILE A 195
ILE A 148
ILE A 105
 None
 1.13A 6ebpD-3nd0A:
undetectable		 6ebpD-3nd0A:
8.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EMU_A_SAMA501_0
(TRNA
(GUANINE(9)-/ADENINE
(9)-N1)-METHYLTRANSF
ERASE)		 3nd0 SLL0855 PROTEIN
(Synechocystis
sp.
PCC
6803) 		5 / 12 PRO A 106
GLY A 347
ILE A 348
ILE A 108
ILE A 148
 None
CL  A 467 ( 3.9A)
CL  A 467 (-4.6A)
None
None
 0.99A 6emuA-3nd0A:
undetectable		 6emuA-3nd0A:
16.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FGC_A_D95A816_0
(GEPHYRIN)		 3nd0 SLL0855 PROTEIN
(Synechocystis
sp.
PCC
6803) 		5 / 11 MET A 260
PHE A 257
LEU A 253
LEU A 389
ILE A 358
 None
 1.47A 6fgcA-3nd0A:
undetectable		 6fgcA-3nd0A:
11.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HU9_E_PCFE202_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 5A,
MITOCHONDRIAL
CYTOCHROME C OXIDASE
SUBUNIT 1)		 3nd0 SLL0855 PROTEIN
(Synechocystis
sp.
PCC
6803) 		4 / 8 GLN A  62
ALA A  52
VAL A  53
MET A  56
 None
 1.05A 6hu9a-3nd0A:
undetectable
6hu9e-3nd0A:
undetectable		 6hu9a-3nd0A:
26.22
6hu9e-3nd0A:
15.47