SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3nd1'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1L7F_A_BCZA801_1
(NEURAMINIDASE)		 3nd1 PRECORRIN-6A
SYNTHASE/COBF
PROTEIN
(Rhodobacter
capsulatus) 		3 / 3 ARG A 172
ARG A 232
ARG A 169
 None
 1.10A 1l7fA-3nd1A:
undetectable		 1l7fA-3nd1A:
22.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1L7H_A_BCZA801_1
(NEURAMINIDASE)		 3nd1 PRECORRIN-6A
SYNTHASE/COBF
PROTEIN
(Rhodobacter
capsulatus) 		3 / 3 ARG A 172
ARG A 232
ARG A 169
 None
 1.10A 1l7hA-3nd1A:
undetectable		 1l7hA-3nd1A:
22.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JKJ_D_CLMD1142_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)		 3nd1 PRECORRIN-6A
SYNTHASE/COBF
PROTEIN
(Rhodobacter
capsulatus) 		4 / 5 PRO A 212
PRO A  14
ILE A  50
GLY A  12
 None
 0.89A 2jkjD-3nd1A:
undetectable		 2jkjD-3nd1A:
19.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JKJ_F_CLMF1143_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)		 3nd1 PRECORRIN-6A
SYNTHASE/COBF
PROTEIN
(Rhodobacter
capsulatus) 		4 / 5 PRO A 212
PRO A  14
ILE A  50
GLY A  12
 None
 0.89A 2jkjF-3nd1A:
undetectable		 2jkjF-3nd1A:
19.86
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2NPN_A_SAMA4633_0
(PUTATIVE COBALAMIN
SYNTHESIS RELATED
PROTEIN)		 3nd1 PRECORRIN-6A
SYNTHASE/COBF
PROTEIN
(Rhodobacter
capsulatus) 		6 / 9 LEU A 117
TYR A 118
THR A 143
ALA A 144
LEU A 187
LEU A 148
 SAH  A 300 (-3.9A)
None
ACT  A2384 (-3.9A)
SAH  A 300 (-3.3A)
SAH  A 300 (-4.6A)
None
 1.31A 2npnA-3nd1A:
27.5		 2npnA-3nd1A:
38.32
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2NPN_A_SAMA4633_0
(PUTATIVE COBALAMIN
SYNTHESIS RELATED
PROTEIN)		 3nd1 PRECORRIN-6A
SYNTHASE/COBF
PROTEIN
(Rhodobacter
capsulatus) 		7 / 9 THR A  11
GLY A 113
LEU A 117
TYR A 118
THR A 143
ALA A 144
LEU A 187
 SAH  A 300 (-4.4A)
SAH  A 300 (-3.4A)
SAH  A 300 (-3.9A)
None
ACT  A2384 (-3.9A)
SAH  A 300 (-3.3A)
SAH  A 300 (-4.6A)
 0.44A 2npnA-3nd1A:
27.5		 2npnA-3nd1A:
38.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P50_A_PFLA319_1
(GLR4197 PROTEIN)		 3nd1 PRECORRIN-6A
SYNTHASE/COBF
PROTEIN
(Rhodobacter
capsulatus) 		4 / 7 ILE A   7
LEU A 110
THR A  18
ILE A  17
 None
 0.75A 3p50A-3nd1A:
undetectable		 3p50A-3nd1A:
24.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P50_B_PFLB319_1
(GLR4197 PROTEIN)		 3nd1 PRECORRIN-6A
SYNTHASE/COBF
PROTEIN
(Rhodobacter
capsulatus) 		4 / 7 ILE A   7
LEU A 110
THR A  18
ILE A  17
 None
 0.75A 3p50B-3nd1A:
undetectable		 3p50B-3nd1A:
24.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P50_C_PFLC319_1
(GLR4197 PROTEIN)		 3nd1 PRECORRIN-6A
SYNTHASE/COBF
PROTEIN
(Rhodobacter
capsulatus) 		4 / 7 ILE A   7
LEU A 110
THR A  18
ILE A  17
 None
 0.74A 3p50C-3nd1A:
undetectable		 3p50C-3nd1A:
24.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P50_D_PFLD320_1
(GLR4197 PROTEIN)		 3nd1 PRECORRIN-6A
SYNTHASE/COBF
PROTEIN
(Rhodobacter
capsulatus) 		4 / 7 ILE A   7
LEU A 110
THR A  18
ILE A  17
 None
 0.74A 3p50D-3nd1A:
undetectable		 3p50D-3nd1A:
24.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P50_E_PFLE319_1
(GLR4197 PROTEIN)		 3nd1 PRECORRIN-6A
SYNTHASE/COBF
PROTEIN
(Rhodobacter
capsulatus) 		4 / 7 ILE A   7
LEU A 110
THR A  18
ILE A  17
 None
 0.74A 3p50E-3nd1A:
undetectable		 3p50E-3nd1A:
24.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3S54_B_017B201_1
(PROTEASE)		 3nd1 PRECORRIN-6A
SYNTHASE/COBF
PROTEIN
(Rhodobacter
capsulatus) 		5 / 12 LEU A 110
ALA A  24
GLY A  19
ILE A   9
ILE A   7
 None
 0.92A 3s54A-3nd1A:
undetectable		 3s54A-3nd1A:
15.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C9K_B_CAMB424_0
(CYTOCHROME P450)		 3nd1 PRECORRIN-6A
SYNTHASE/COBF
PROTEIN
(Rhodobacter
capsulatus) 		5 / 9 TYR A 246
THR A 166
LEU A 171
GLY A 175
VAL A 164
 None
 1.42A 4c9kB-3nd1A:
undetectable		 4c9kB-3nd1A:
21.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4H1N_A_CGEA505_1
(CYTOCHROME P450 2B4)		 3nd1 PRECORRIN-6A
SYNTHASE/COBF
PROTEIN
(Rhodobacter
capsulatus) 		5 / 11 ILE A   9
ILE A  17
ALA A  53
ALA A  52
ILE A  31
 None
 1.12A 4h1nA-3nd1A:
undetectable		 4h1nA-3nd1A:
21.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AXA_A_ADNA502_2
(ADENOSYLHOMOCYSTEINA
SE)		 3nd1 PRECORRIN-6A
SYNTHASE/COBF
PROTEIN
(Rhodobacter
capsulatus) 		4 / 5 GLU A  90
THR A  91
THR A 121
LEU A   4
 None
 1.26A 5axaA-3nd1A:
undetectable		 5axaA-3nd1A:
20.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AXA_C_ADNC502_2
(ADENOSYLHOMOCYSTEINA
SE)		 3nd1 PRECORRIN-6A
SYNTHASE/COBF
PROTEIN
(Rhodobacter
capsulatus) 		4 / 5 GLU A  90
THR A  91
THR A 121
LEU A   4
 None
 1.26A 5axaC-3nd1A:
undetectable		 5axaC-3nd1A:
20.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EB3_A_UEGA202_1
(YFIR)		 3nd1 PRECORRIN-6A
SYNTHASE/COBF
PROTEIN
(Rhodobacter
capsulatus) 		4 / 4 LEU A  93
ILE A  96
PRO A 133
LEU A 134
 None
 1.24A 5eb3A-3nd1A:
undetectable		 5eb3A-3nd1A:
21.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OG9_B_TESB502_1
(-)		 3nd1 PRECORRIN-6A
SYNTHASE/COBF
PROTEIN
(Rhodobacter
capsulatus) 		5 / 12 TRP A  84
ILE A 124
LEU A  67
PRO A 115
LEU A 109
 None
 1.07A 5og9B-3nd1A:
undetectable		 5og9B-3nd1A:
20.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5V96_A_ADNA502_2
(S-ADENOSYL-L-HOMOCYS
TEINE HYDROLASE)		 3nd1 PRECORRIN-6A
SYNTHASE/COBF
PROTEIN
(Rhodobacter
capsulatus) 		4 / 4 GLU A  90
THR A  91
THR A 121
LEU A   4
 None
 1.27A 5v96A-3nd1A:
undetectable		 5v96A-3nd1A:
21.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5V96_B_ADNB502_2
(S-ADENOSYL-L-HOMOCYS
TEINE HYDROLASE)		 3nd1 PRECORRIN-6A
SYNTHASE/COBF
PROTEIN
(Rhodobacter
capsulatus) 		4 / 4 GLU A  90
THR A  91
THR A 121
LEU A   4
 None
 1.31A 5v96B-3nd1A:
undetectable		 5v96B-3nd1A:
21.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5V96_C_ADNC502_2
(S-ADENOSYL-L-HOMOCYS
TEINE HYDROLASE)		 3nd1 PRECORRIN-6A
SYNTHASE/COBF
PROTEIN
(Rhodobacter
capsulatus) 		4 / 4 GLU A  90
THR A  91
THR A 121
LEU A   4
 None
 1.28A 5v96C-3nd1A:
undetectable		 5v96C-3nd1A:
21.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5V96_D_ADND502_2
(S-ADENOSYL-L-HOMOCYS
TEINE HYDROLASE)		 3nd1 PRECORRIN-6A
SYNTHASE/COBF
PROTEIN
(Rhodobacter
capsulatus) 		4 / 4 GLU A  90
THR A  91
THR A 121
LEU A   4
 None
 1.27A 5v96D-3nd1A:
undetectable		 5v96D-3nd1A:
21.59