SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3nd6'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z95_A_198A501_2
(ANDROGEN RECEPTOR)		 3nd6 PHOSPHOPANTETHEINE
ADENYLYLTRANSFERASE
(Enterococcus
faecalis) 		4 / 6 LEU A 147
ASN A  16
LEU A  54
ILE A  22
 None
 1.00A 1z95A-3nd6A:
undetectable		 1z95A-3nd6A:
22.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EJT_A_SAMA501_0
(N(2),N(2)-DIMETHYLGU
ANOSINE TRNA
METHYLTRANSFERASE)		 3nd6 PHOSPHOPANTETHEINE
ADENYLYLTRANSFERASE
(Enterococcus
faecalis) 		5 / 12 LEU A  54
ALA A  58
ALA A 154
PHE A  11
PHE A  46
 None
 1.04A 2ejtA-3nd6A:
undetectable		 2ejtA-3nd6A:
19.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AZT_A_SAMA1472_0
(METHYLTRANSFERASE
WBDD)		 3nd6 PHOSPHOPANTETHEINE
ADENYLYLTRANSFERASE
(Enterococcus
faecalis) 		5 / 12 ALA A  26
ASN A  64
ILE A  34
LEU A  21
ILE A  55
 None
None
None
ATP  A 961 (-4.4A)
None
 1.14A 4aztA-3nd6A:
3.3		 4aztA-3nd6A:
15.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AZV_A_SAMA1474_0
(WBDD)		 3nd6 PHOSPHOPANTETHEINE
ADENYLYLTRANSFERASE
(Enterococcus
faecalis) 		6 / 12 ALA A  26
ILE A  33
ASN A  64
ILE A  34
LEU A  21
ILE A  55
 None
None
None
None
ATP  A 961 (-4.4A)
None
 1.18A 4azvA-3nd6A:
3.3		 4azvA-3nd6A:
15.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OKW_A_198A1001_2
(ANDROGEN RECEPTOR)		 3nd6 PHOSPHOPANTETHEINE
ADENYLYLTRANSFERASE
(Enterococcus
faecalis) 		4 / 7 LEU A 147
ASN A  16
LEU A  54
ILE A  22
 None
 0.97A 4okwA-3nd6A:
undetectable		 4okwA-3nd6A:
22.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZE0_A_VORA602_1
(LANOSTEROL 14-ALPHA
DEMETHYLASE)		 3nd6 PHOSPHOPANTETHEINE
ADENYLYLTRANSFERASE
(Enterococcus
faecalis) 		5 / 9 THR A  72
ILE A  38
GLY A   9
LEU A   6
LEU A  82
 None
None
ATP  A 961 ( 3.7A)
None
None
 1.36A 4ze0A-3nd6A:
undetectable		 4ze0A-3nd6A:
17.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HG0_B_SAMB301_0
(PANTOTHENATE
SYNTHETASE)		 3nd6 PHOSPHOPANTETHEINE
ADENYLYLTRANSFERASE
(Enterococcus
faecalis) 		5 / 12 GLY A  17
HIS A  18
LEU A  21
GLY A  90
ASP A  96
 ATP  A 961 (-3.4A)
ATP  A 961 (-4.3A)
ATP  A 961 (-4.4A)
ATP  A 961 (-3.7A)
ATP  A 961 ( 3.9A)
 1.05A 5hg0B-3nd6A:
8.8		 5hg0B-3nd6A:
23.70
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6JMJ_A_ASCA201_0
(PHOSPHOPANTETHEINE
ADENYLYLTRANSFERASE)		 3nd6 PHOSPHOPANTETHEINE
ADENYLYLTRANSFERASE
(Enterococcus
faecalis) 		4 / 5 GLY A   9
HIS A  18
SER A 129
SER A 130
 ATP  A 961 ( 3.7A)
ATP  A 961 (-4.3A)
ATP  A 961 (-3.4A)
ATP  A 961 (-3.6A)
 0.31A 6jmjA-3nd6A:
23.9		 6jmjA-3nd6A:
35.47
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6JNH_A_ASCA201_0
(PHOSPHOPANTETHEINE
ADENYLYLTRANSFERASE)		 3nd6 PHOSPHOPANTETHEINE
ADENYLYLTRANSFERASE
(Enterococcus
faecalis) 		5 / 7 GLY A   9
PHE A  11
HIS A  18
SER A 129
SER A 130
 ATP  A 961 ( 3.7A)
None
ATP  A 961 (-4.3A)
ATP  A 961 (-3.4A)
ATP  A 961 (-3.6A)
 0.29A 6jnhA-3nd6A:
24.0		 6jnhA-3nd6A:
35.47
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6JNH_A_ASCA201_0
(PHOSPHOPANTETHEINE
ADENYLYLTRANSFERASE)		 3nd6 PHOSPHOPANTETHEINE
ADENYLYLTRANSFERASE
(Enterococcus
faecalis) 		4 / 7 HIS A  18
ARG A  92
SER A 129
SER A 130
 ATP  A 961 (-4.3A)
ATP  A 961 (-3.5A)
ATP  A 961 (-3.4A)
ATP  A 961 (-3.6A)
 0.85A 6jnhA-3nd6A:
24.0		 6jnhA-3nd6A:
35.47
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6JOG_A_ASCA201_0
(PHOSPHOPANTETHEINE
ADENYLYLTRANSFERASE)		 3nd6 PHOSPHOPANTETHEINE
ADENYLYLTRANSFERASE
(Enterococcus
faecalis) 		4 / 6 GLY A   9
HIS A  18
SER A 129
SER A 130
 ATP  A 961 ( 3.7A)
ATP  A 961 (-4.3A)
ATP  A 961 (-3.4A)
ATP  A 961 (-3.6A)
 0.35A 6jogA-3nd6A:
23.9		 6jogA-3nd6A:
35.47
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6JOG_A_ASCA201_0
(PHOSPHOPANTETHEINE
ADENYLYLTRANSFERASE)		 3nd6 PHOSPHOPANTETHEINE
ADENYLYLTRANSFERASE
(Enterococcus
faecalis) 		4 / 6 HIS A  18
ARG A  92
SER A 129
SER A 130
 ATP  A 961 (-4.3A)
ATP  A 961 (-3.5A)
ATP  A 961 (-3.4A)
ATP  A 961 (-3.6A)
 0.86A 6jogA-3nd6A:
23.9		 6jogA-3nd6A:
35.47