SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3ndh'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1KIA_C_SAMC2293_1 (GLYCINE N-METHYLTRANSFERASE)	3ndh	RESTRICTION ENDONUCLEASE THAI (Thermoplasma acidophilum)	4 / 6	TRP A 107 ASP A 82 SER A 91 SER A 51	None NA A 217 ( 2.7A) NA A 217 ( 4.6A) None	0.95A	1kiaC-3ndhA: undetectable	1kiaC-3ndhA: 19.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4XZK_A_AG2A700_1 (PUTATIVE NAD(+)--ARGININE ADP-RIBOSYLTRANSFERA SE VIS)	3ndh	RESTRICTION ENDONUCLEASE THAI (Thermoplasma acidophilum)	4 / 7	TYR A 160 SER A 176 GLU A 182 GLU A 178	None	1.21A	4xzkA-3ndhA: undetectable	4xzkA-3ndhA: 24.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6CDU_I_EY4I500_0 (CHIMERIC ALPHA1GABAA RECEPTOR)	3ndh	RESTRICTION ENDONUCLEASE THAI (Thermoplasma acidophilum)	4 / 5	GLN A 149 VAL A 147 PRO A 123 THR A 185	None	1.47A	6cduI-3ndhA: undetectable 6cduJ-3ndhA: undetectable	6cduI-3ndhA: 22.39 6cduJ-3ndhA: 22.39