SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3ndn'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1AQB_A_RTLA185_0
(RETINOL-BINDING
PROTEIN)		 3ndn O-SUCCINYLHOMOSERINE
SULFHYDRYLASE
(Mycobacterium
tuberculosis) 		5 / 10 LEU A 301
VAL A 296
GLN A 281
HIS A 220
PHE A 197
 None
None
None
LLP  A 219 ( 4.8A)
None
 1.20A 1aqbA-3ndnA:
undetectable		 1aqbA-3ndnA:
19.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1S9Q_A_CHDA459_0
(ESTROGEN-RELATED
RECEPTOR GAMMA)		 3ndn O-SUCCINYLHOMOSERINE
SULFHYDRYLASE
(Mycobacterium
tuberculosis) 		4 / 6 ASP A 347
LEU A 358
VAL A 359
ILE A 387
 None
 0.90A 1s9qA-3ndnA:
undetectable		 1s9qA-3ndnA:
23.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SV9_A_DIFA701_1
(PHOSPHOLIPASE A2)		 3ndn O-SUCCINYLHOMOSERINE
SULFHYDRYLASE
(Mycobacterium
tuberculosis) 		4 / 8 ALA A 280
ILE A 283
GLY A 390
HIS A 220
 None
None
None
LLP  A 219 ( 4.8A)
 0.73A 1sv9A-3ndnA:
undetectable		 1sv9A-3ndnA:
14.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BR4_F_SAMF301_1
(CEPHALOSPORIN
HYDROXYLASE CMCI)		 3ndn O-SUCCINYLHOMOSERINE
SULFHYDRYLASE
(Mycobacterium
tuberculosis) 		3 / 3 LYS A 220
ASP A 194
CYH A 125
 LLP  A 219 ( 2.9A)
LLP  A 219 ( 3.1A)
LLP  A 219 ( 4.1A)
 1.40A 2br4F-3ndnA:
3.5		 2br4F-3ndnA:
20.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PYN_A_1UNA1001_3
(PROTEASE RETROPEPSIN)		 3ndn O-SUCCINYLHOMOSERINE
SULFHYDRYLASE
(Mycobacterium
tuberculosis) 		3 / 3 ASP A 354
THR A 199
PRO A 200
 None
 0.48A 2pynB-3ndnA:
undetectable		 2pynB-3ndnA:
12.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q64_B_1UNB1001_4
(PROTEASE RETROPEPSIN)		 3ndn O-SUCCINYLHOMOSERINE
SULFHYDRYLASE
(Mycobacterium
tuberculosis) 		3 / 3 ASP A 354
THR A 199
PRO A 200
 None
 0.52A 2q64B-3ndnA:
undetectable		 2q64B-3ndnA:
13.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QAK_A_1UNA1001_4
(PROTEASE RETROPEPSIN)		 3ndn O-SUCCINYLHOMOSERINE
SULFHYDRYLASE
(Mycobacterium
tuberculosis) 		3 / 3 ASP A 354
THR A 199
PRO A 200
 None
 0.46A 2qakB-3ndnA:
undetectable		 2qakB-3ndnA:
13.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XAT_A_CLMA301_0
(XENOBIOTIC
ACETYLTRANSFERASE)		 3ndn O-SUCCINYLHOMOSERINE
SULFHYDRYLASE
(Mycobacterium
tuberculosis) 		3 / 3 GLY A  45
TYR A  67
SER A  44
 None
 0.75A 2xatA-3ndnA:
undetectable		 2xatA-3ndnA:
20.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BWC_B_SAMB501_0
(SPERMIDINE SYNTHASE)		 3ndn O-SUCCINYLHOMOSERINE
SULFHYDRYLASE
(Mycobacterium
tuberculosis) 		5 / 12 LEU A 108
GLY A 234
ILE A 232
VAL A 192
ASP A 235
 None
 0.92A 3bwcB-3ndnA:
5.1		 3bwcB-3ndnA:
23.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EM0_B_CHDB151_0
(ILEAL BILE
ACID-BINDING PROTEIN)		 3ndn O-SUCCINYLHOMOSERINE
SULFHYDRYLASE
(Mycobacterium
tuberculosis) 		5 / 12 ILE A 346
ILE A 387
VAL A 321
LEU A 325
LEU A 340
 None
 1.07A 3em0B-3ndnA:
undetectable		 3em0B-3ndnA:
17.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IB0_A_DIFA701_1
(LACTOTRANSFERRIN)		 3ndn O-SUCCINYLHOMOSERINE
SULFHYDRYLASE
(Mycobacterium
tuberculosis) 		4 / 4 PRO A 299
TYR A 300
GLY A 318
THR A 319
 None
 1.49A 3ib0A-3ndnA:
undetectable		 3ib0A-3ndnA:
22.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TKG_C_ROCC901_3
(PROTEASE)		 3ndn O-SUCCINYLHOMOSERINE
SULFHYDRYLASE
(Mycobacterium
tuberculosis) 		3 / 3 ASP A 354
THR A 199
PRO A 200
 None
 0.55A 3tkgD-3ndnA:
undetectable		 3tkgD-3ndnA:
13.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C9N_B_CAMB1420_0
(CYTOCHROME P450)		 3ndn O-SUCCINYLHOMOSERINE
SULFHYDRYLASE
(Mycobacterium
tuberculosis) 		5 / 10 THR A 181
THR A 166
LEU A 193
GLY A 205
ASP A 176
 None
 1.13A 4c9nB-3ndnA:
undetectable		 4c9nB-3ndnA:
20.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C9P_B_CAMB423_0
(CYTOCHROME P450)		 3ndn O-SUCCINYLHOMOSERINE
SULFHYDRYLASE
(Mycobacterium
tuberculosis) 		5 / 10 THR A 181
THR A 166
LEU A 193
GLY A 205
ASP A 176
 None
 1.05A 4c9pB-3ndnA:
undetectable		 4c9pB-3ndnA:
20.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YHA_A_MZMA303_1
(ALPHA-CARBONIC
ANHYDRASE)		 3ndn O-SUCCINYLHOMOSERINE
SULFHYDRYLASE
(Mycobacterium
tuberculosis) 		5 / 12 ASP A 354
HIS A 275
VAL A 389
LEU A 397
THR A 394
 None
 1.30A 4yhaA-3ndnA:
undetectable		 4yhaA-3ndnA:
20.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YHA_B_MZMB303_1
(ALPHA-CARBONIC
ANHYDRASE)		 3ndn O-SUCCINYLHOMOSERINE
SULFHYDRYLASE
(Mycobacterium
tuberculosis) 		5 / 10 ASP A 354
HIS A 275
VAL A 389
LEU A 397
THR A 394
 None
 1.28A 4yhaB-3ndnA:
undetectable		 4yhaB-3ndnA:
20.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YHA_C_MZMC303_1
(ALPHA-CARBONIC
ANHYDRASE)		 3ndn O-SUCCINYLHOMOSERINE
SULFHYDRYLASE
(Mycobacterium
tuberculosis) 		5 / 11 ASP A 354
HIS A 275
VAL A 389
LEU A 397
THR A 394
 None
 1.28A 4yhaC-3ndnA:
undetectable		 4yhaC-3ndnA:
20.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KSG_B_NIZB809_1
(CATALASE-PEROXIDASE)		 3ndn O-SUCCINYLHOMOSERINE
SULFHYDRYLASE
(Mycobacterium
tuberculosis) 		5 / 9 GLU A  38
VAL A  77
GLY A 265
LEU A 266
THR A 268
 None
 1.27A 5ksgB-3ndnA:
undetectable		 5ksgB-3ndnA:
22.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KSN_A_NIZA809_1
(CATALASE-PEROXIDASE)		 3ndn O-SUCCINYLHOMOSERINE
SULFHYDRYLASE
(Mycobacterium
tuberculosis) 		5 / 9 GLU A  38
VAL A  77
GLY A 265
LEU A 266
THR A 268
 None
 1.33A 5ksnA-3ndnA:
undetectable		 5ksnA-3ndnA:
22.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KSN_B_NIZB809_1
(CATALASE-PEROXIDASE)		 3ndn O-SUCCINYLHOMOSERINE
SULFHYDRYLASE
(Mycobacterium
tuberculosis) 		5 / 9 GLU A  38
VAL A  77
GLY A 265
LEU A 266
THR A 268
 None
 1.30A 5ksnB-3ndnA:
undetectable		 5ksnB-3ndnA:
22.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KT8_B_NIZB809_1
(CATALASE-PEROXIDASE)		 3ndn O-SUCCINYLHOMOSERINE
SULFHYDRYLASE
(Mycobacterium
tuberculosis) 		5 / 9 GLU A  38
VAL A  77
GLY A 265
LEU A 266
THR A 268
 None
 1.27A 5kt8B-3ndnA:
undetectable		 5kt8B-3ndnA:
22.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LG3_F_Z80F401_1
(GAMMA-AMINOBUTYRIC-A
CID RECEPTOR SUBUNIT
BETA-1)		 3ndn O-SUCCINYLHOMOSERINE
SULFHYDRYLASE
(Mycobacterium
tuberculosis) 		5 / 10 ILE A 387
ILE A 401
PHE A 286
VAL A 389
ASP A 396
 None
 1.24A 5lg3F-3ndnA:
undetectable		 5lg3F-3ndnA:
20.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LG3_G_Z80G401_1
(GAMMA-AMINOBUTYRIC-A
CID RECEPTOR SUBUNIT
BETA-1)		 3ndn O-SUCCINYLHOMOSERINE
SULFHYDRYLASE
(Mycobacterium
tuberculosis) 		5 / 10 ILE A 387
ILE A 401
PHE A 286
VAL A 389
ASP A 396
 None
 1.25A 5lg3G-3ndnA:
undetectable		 5lg3G-3ndnA:
20.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LG3_H_Z80H401_1
(GAMMA-AMINOBUTYRIC-A
CID RECEPTOR SUBUNIT
BETA-1)		 3ndn O-SUCCINYLHOMOSERINE
SULFHYDRYLASE
(Mycobacterium
tuberculosis) 		5 / 10 ILE A 387
ILE A 401
PHE A 286
VAL A 389
ASP A 396
 None
 1.22A 5lg3H-3ndnA:
undetectable		 5lg3H-3ndnA:
20.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5SXQ_A_NIZA808_1
(CATALASE-PEROXIDASE)		 3ndn O-SUCCINYLHOMOSERINE
SULFHYDRYLASE
(Mycobacterium
tuberculosis) 		5 / 8 GLU A  38
VAL A  77
GLY A 265
LEU A 266
THR A 268
 None
 1.35A 5sxqA-3ndnA:
undetectable		 5sxqA-3ndnA:
22.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5SXS_B_NIZB806_1
(CATALASE-PEROXIDASE)		 3ndn O-SUCCINYLHOMOSERINE
SULFHYDRYLASE
(Mycobacterium
tuberculosis) 		5 / 9 GLU A  38
VAL A  77
GLY A 265
LEU A 266
THR A 268
 None
 1.30A 5sxsB-3ndnA:
undetectable		 5sxsB-3ndnA:
22.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5SXT_A_NIZA807_1
(CATALASE-PEROXIDASE)		 3ndn O-SUCCINYLHOMOSERINE
SULFHYDRYLASE
(Mycobacterium
tuberculosis) 		5 / 8 GLU A  38
VAL A  77
GLY A 265
LEU A 266
THR A 268
 None
 1.28A 5sxtA-3ndnA:
undetectable		 5sxtA-3ndnA:
21.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5SXT_B_NIZB808_1
(CATALASE-PEROXIDASE)		 3ndn O-SUCCINYLHOMOSERINE
SULFHYDRYLASE
(Mycobacterium
tuberculosis) 		5 / 8 GLU A  38
VAL A  77
GLY A 265
LEU A 266
THR A 268
 None
 1.27A 5sxtB-3ndnA:
undetectable		 5sxtB-3ndnA:
21.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5SYI_B_NIZB805_1
(CATALASE-PEROXIDASE)		 3ndn O-SUCCINYLHOMOSERINE
SULFHYDRYLASE
(Mycobacterium
tuberculosis) 		5 / 9 GLU A  38
VAL A  77
GLY A 265
LEU A 266
THR A 268
 None
 1.29A 5syiB-3ndnA:
undetectable		 5syiB-3ndnA:
22.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5SYJ_B_NIZB809_1
(CATALASE-PEROXIDASE)		 3ndn O-SUCCINYLHOMOSERINE
SULFHYDRYLASE
(Mycobacterium
tuberculosis) 		5 / 8 GLU A  38
VAL A  77
GLY A 265
LEU A 266
THR A 268
 None
 1.28A 5syjB-3ndnA:
undetectable		 5syjB-3ndnA:
22.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TZO_B_7V7B201_1
(ENDO-1,4-BETA-XYLANA
SE A)		 3ndn O-SUCCINYLHOMOSERINE
SULFHYDRYLASE
(Mycobacterium
tuberculosis) 		5 / 12 LEU A 105
VAL A 101
ALA A 231
ALA A 100
GLY A  97
 None
None
None
None
LLP  A 219 ( 3.2A)
 1.17A 5tzoB-3ndnA:
undetectable		 5tzoB-3ndnA:
17.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BRD_B_RFPB502_2
(RIFAMPIN
MONOOXYGENASE)		 3ndn O-SUCCINYLHOMOSERINE
SULFHYDRYLASE
(Mycobacterium
tuberculosis) 		4 / 6 GLN A 172
VAL A 384
LEU A 174
PRO A 305
 None
 1.26A 6brdB-3ndnA:
undetectable		 6brdB-3ndnA:
11.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CDQ_A_NIZA809_1
(CATALASE-PEROXIDASE)		 3ndn O-SUCCINYLHOMOSERINE
SULFHYDRYLASE
(Mycobacterium
tuberculosis) 		5 / 9 GLU A  38
VAL A  77
GLY A 265
LEU A 266
THR A 268
 None
 1.29A 6cdqA-3ndnA:
undetectable		 6cdqA-3ndnA:
10.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CDQ_B_NIZB808_1
(CATALASE-PEROXIDASE)		 3ndn O-SUCCINYLHOMOSERINE
SULFHYDRYLASE
(Mycobacterium
tuberculosis) 		5 / 9 GLU A  38
VAL A  77
GLY A 265
LEU A 266
THR A 268
 None
 1.26A 6cdqB-3ndnA:
undetectable		 6cdqB-3ndnA:
10.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CFQ_B_NIZB809_1
(CATALASE-PEROXIDASE)		 3ndn O-SUCCINYLHOMOSERINE
SULFHYDRYLASE
(Mycobacterium
tuberculosis) 		5 / 9 GLU A  38
VAL A  77
GLY A 265
LEU A 266
THR A 268
 None
 1.31A 6cfqB-3ndnA:
undetectable		 6cfqB-3ndnA:
10.68