SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3ne7'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BFP_A_H4BA1290_1
(PTERIDINE REDUCTASE
1)		 3ne7 ACETYLTRANSFERASE
(Thermoplasma
acidophilum) 		4 / 8 PHE A 143
LEU A 108
TYR A 138
LEU A  80
 None
None
BME  A 162 ( 4.9A)
BME  A 163 (-4.9A)
 1.05A 2bfpA-3ne7A:
undetectable		 2bfpA-3ne7A:
19.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EJT_A_SAMA501_0
(N(2),N(2)-DIMETHYLGU
ANOSINE TRNA
METHYLTRANSFERASE)		 3ne7 ACETYLTRANSFERASE
(Thermoplasma
acidophilum) 		5 / 12 LEU A  16
SER A  46
ALA A  20
ASP A  12
PHE A  77
 None
 1.19A 2ejtA-3ne7A:
undetectable		 2ejtA-3ne7A:
17.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DZK_Y_BEZY801_0
(ATP-DEPENDENT CLP
PROTEASE PROTEOLYTIC
SUBUNIT 1
ATP-DEPENDENT CLP
PROTEASE PROTEOLYTIC
SUBUNIT 2
BEZ-LEU-LEU)		 3ne7 ACETYLTRANSFERASE
(Thermoplasma
acidophilum) 		4 / 5 ILE A  75
GLY A  67
ILE A 103
LEU A  74
 None
None
COA  A 161 (-4.9A)
None
 0.91A 5dzkd-3ne7A:
undetectable
5dzkk-3ne7A:
undetectable
5dzky-3ne7A:
undetectable		 5dzkd-3ne7A:
19.72
5dzkk-3ne7A:
21.63
5dzky-3ne7A:
3.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DZK_Z_BEZZ801_0
(ATP-DEPENDENT CLP
PROTEASE PROTEOLYTIC
SUBUNIT 1
BEZ-LEU-LEU)		 3ne7 ACETYLTRANSFERASE
(Thermoplasma
acidophilum) 		4 / 4 ILE A  75
GLY A  67
ILE A 103
LEU A  74
 None
None
COA  A 161 (-4.9A)
None
 0.90A 5dzkl-3ne7A:
undetectable
5dzkz-3ne7A:
undetectable		 5dzkl-3ne7A:
21.63
5dzkz-3ne7A:
3.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IFU_B_GBMB801_1
(PROLINE--TRNA LIGASE)		 3ne7 ACETYLTRANSFERASE
(Thermoplasma
acidophilum) 		5 / 9 ILE A  17
LEU A  16
GLU A  53
ARG A  56
ILE A  54
 None
None
UNL  A 166 ( 3.6A)
UNL  A 166 ( 3.1A)
None
 1.45A 5ifuB-3ne7A:
undetectable		 5ifuB-3ne7A:
15.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KBW_B_RBFB201_1
(RIBOFLAVIN
TRANSPORTER RIBU)		 3ne7 ACETYLTRANSFERASE
(Thermoplasma
acidophilum) 		5 / 12 GLU A 112
LEU A 125
GLY A 142
ASN A 141
VAL A 145
 None
BME  A 162 ( 3.9A)
None
GOL  A 165 (-3.0A)
None
 1.20A 5kbwB-3ne7A:
undetectable		 5kbwB-3ne7A:
25.91