SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3ne9'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KXH_A_ACRA598_2
(ALPHA-AMYLASE)		 3ne9 PHOSPHOPANTETHEINE
PROTEIN TRANSFERASE,
PPT1P
(Corynebacterium
ammoniagenes) 		3 / 3 TRP A  80
TYR A 151
LEU A 132
 None
 1.07A 1kxhA-3ne9A:
undetectable		 1kxhA-3ne9A:
15.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1WMQ_A_HISA2001_0
(HUT OPERON POSITIVE
REGULATORY PROTEIN)		 3ne9 PHOSPHOPANTETHEINE
PROTEIN TRANSFERASE,
PPT1P
(Corynebacterium
ammoniagenes) 		4 / 6 ARG A  69
ILE A 136
GLY A  68
ALA A  67
 None
 0.88A 1wmqA-3ne9A:
undetectable		 1wmqA-3ne9A:
24.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1WMQ_B_HISB1001_0
(HUT OPERON POSITIVE
REGULATORY PROTEIN)		 3ne9 PHOSPHOPANTETHEINE
PROTEIN TRANSFERASE,
PPT1P
(Corynebacterium
ammoniagenes) 		4 / 6 ARG A  69
ILE A 136
GLY A  68
ALA A  67
 None
 0.88A 1wmqB-3ne9A:
undetectable		 1wmqB-3ne9A:
24.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1WPU_A_HISA2001_0
(HUT OPERON POSITIVE
REGULATORY PROTEIN)		 3ne9 PHOSPHOPANTETHEINE
PROTEIN TRANSFERASE,
PPT1P
(Corynebacterium
ammoniagenes) 		4 / 6 ARG A  69
ILE A 136
GLY A  68
ALA A  67
 None
 0.86A 1wpuA-3ne9A:
undetectable		 1wpuA-3ne9A:
24.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1WPU_B_HISB1001_0
(HUT OPERON POSITIVE
REGULATORY PROTEIN)		 3ne9 PHOSPHOPANTETHEINE
PROTEIN TRANSFERASE,
PPT1P
(Corynebacterium
ammoniagenes) 		4 / 6 ARG A  69
ILE A 136
GLY A  68
ALA A  67
 None
 0.87A 1wpuB-3ne9A:
undetectable		 1wpuB-3ne9A:
24.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1WRQ_A_HISA2001_0
(HUT OPERON POSITIVE
REGULATORY PROTEIN)		 3ne9 PHOSPHOPANTETHEINE
PROTEIN TRANSFERASE,
PPT1P
(Corynebacterium
ammoniagenes) 		4 / 6 ARG A  69
ILE A 136
GLY A  68
ALA A  67
 None
 0.86A 1wrqA-3ne9A:
undetectable		 1wrqA-3ne9A:
24.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1WRQ_B_HISB1001_0
(HUT OPERON POSITIVE
REGULATORY PROTEIN)		 3ne9 PHOSPHOPANTETHEINE
PROTEIN TRANSFERASE,
PPT1P
(Corynebacterium
ammoniagenes) 		4 / 6 ARG A  69
ILE A 136
GLY A  68
ALA A  67
 None
 0.87A 1wrqB-3ne9A:
undetectable		 1wrqB-3ne9A:
24.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2RIW_A_T44A1395_1
(THYROXINE-BINDING
GLOBULIN)		 3ne9 PHOSPHOPANTETHEINE
PROTEIN TRANSFERASE,
PPT1P
(Corynebacterium
ammoniagenes) 		5 / 10 ALA A 145
LEU A 115
LEU A 132
LYS A  78
LEU A 113
 None
None
None
SO4  A 231 (-2.6A)
None
 1.12A 2riwA-3ne9A:
undetectable
2riwB-3ne9A:
undetectable		 2riwA-3ne9A:
19.12
2riwB-3ne9A:
20.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XN6_A_T44A1370_1
(THYROXINE-BINDING
GLOBULIN)		 3ne9 PHOSPHOPANTETHEINE
PROTEIN TRANSFERASE,
PPT1P
(Corynebacterium
ammoniagenes) 		5 / 10 ALA A 145
LEU A 115
LEU A 132
LYS A  78
LEU A 113
 None
None
None
SO4  A 231 (-2.6A)
None
 1.04A 2xn6A-3ne9A:
undetectable
2xn6B-3ne9A:
undetectable		 2xn6A-3ne9A:
17.87
2xn6B-3ne9A:
21.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3O1C_A_ADNA127_1
(HISTIDINE TRIAD
NUCLEOTIDE-BINDING
PROTEIN 1)		 3ne9 PHOSPHOPANTETHEINE
PROTEIN TRANSFERASE,
PPT1P
(Corynebacterium
ammoniagenes) 		5 / 10 ILE A  77
PHE A  76
ILE A 101
ILE A  91
LEU A 123
 None
 1.25A 3o1cA-3ne9A:
undetectable		 3o1cA-3ne9A:
22.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3O1X_A_ADNA1450_1
(HISTIDINE TRIAD
NUCLEOTIDE-BINDING
PROTEIN 1)		 3ne9 PHOSPHOPANTETHEINE
PROTEIN TRANSFERASE,
PPT1P
(Corynebacterium
ammoniagenes) 		5 / 10 ILE A  77
PHE A  76
ILE A 101
ILE A  91
LEU A 123
 None
 1.26A 3o1xA-3ne9A:
undetectable		 3o1xA-3ne9A:
24.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ONN_A_ACTA270_0
(PROTEIN SSM1)		 3ne9 PHOSPHOPANTETHEINE
PROTEIN TRANSFERASE,
PPT1P
(Corynebacterium
ammoniagenes) 		4 / 5 LEU A  38
SER A  36
LEU A 104
PRO A 105
 None
 1.26A 3onnA-3ne9A:
undetectable		 3onnA-3ne9A:
18.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QGZ_A_ADNA127_1
(HISTIDINE TRIAD
NUCLEOTIDE-BINDING
PROTEIN 1)		 3ne9 PHOSPHOPANTETHEINE
PROTEIN TRANSFERASE,
PPT1P
(Corynebacterium
ammoniagenes) 		5 / 10 ILE A  77
PHE A  76
ILE A 101
ILE A  91
LEU A 123
 None
 1.23A 3qgzA-3ne9A:
undetectable		 3qgzA-3ne9A:
22.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HYT_A_OBNA1104_1
(SODIUM/POTASSIUM-TRA
NSPORTING ATPASE
SUBUNIT ALPHA-1)		 3ne9 PHOSPHOPANTETHEINE
PROTEIN TRANSFERASE,
PPT1P
(Corynebacterium
ammoniagenes) 		5 / 12 GLU A  74
ALA A  43
PHE A  35
PHE A  31
LEU A  24
 None
 1.15A 4hytA-3ne9A:
undetectable		 4hytA-3ne9A:
9.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HYT_C_OBNC2004_1
(SODIUM/POTASSIUM-TRA
NSPORTING ATPASE
SUBUNIT ALPHA-1)		 3ne9 PHOSPHOPANTETHEINE
PROTEIN TRANSFERASE,
PPT1P
(Corynebacterium
ammoniagenes) 		5 / 12 GLU A  74
ALA A  43
PHE A  35
PHE A  31
LEU A  24
 None
 1.16A 4hytC-3ne9A:
undetectable		 4hytC-3ne9A:
9.52