SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3nfv'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1BU5_B_RBFB302_1
(PROTEIN (FLAVODOXIN))		 3nfv ALGINATE LYASE
(Bacteroides
ovatus) 		4 / 8 ASP A  54
GLY A 137
ASP A 138
TYR A 141
 None
 0.63A 1bu5B-3nfvA:
undetectable		 1bu5B-3nfvA:
18.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GMK_D_DVAD8_0
(GRAMICIDIN A)		 3nfv ALGINATE LYASE
(Bacteroides
ovatus) 		3 / 3 TRP A 216
VAL A 151
TRP A 152
 None
 1.32A 1gmkC-3nfvA:
undetectable
1gmkD-3nfvA:
undetectable		 1gmkC-3nfvA:
3.06
1gmkD-3nfvA:
3.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HO5_A_ADNA1604_1
(5'-NUCLEOTIDASE)		 3nfv ALGINATE LYASE
(Bacteroides
ovatus) 		5 / 11 ILE A 184
SER A  83
GLY A  85
ARG A 179
ASP A 185
 None
None
None
EDO  A 406 ( 2.9A)
None
 1.25A 1ho5A-3nfvA:
undetectable		 1ho5A-3nfvA:
23.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HO5_A_ADNA1604_1
(5'-NUCLEOTIDASE)		 3nfv ALGINATE LYASE
(Bacteroides
ovatus) 		5 / 11 ILE A 186
SER A  83
GLY A 167
GLY A 182
ASP A 185
 None
 1.34A 1ho5A-3nfvA:
undetectable		 1ho5A-3nfvA:
23.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2J0H_B_ACHB1289_0
(FICOLIN-2)		 3nfv ALGINATE LYASE
(Bacteroides
ovatus) 		4 / 4 ARG A  53
ASP A  54
THR A  50
LYS A  57
 None
 1.38A 2j0hB-3nfvA:
0.0		 2j0hB-3nfvA:
19.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2J0H_C_ACHC1289_0
(FICOLIN-2)		 3nfv ALGINATE LYASE
(Bacteroides
ovatus) 		4 / 4 ARG A  53
ASP A  54
THR A  50
LYS A  57
 None
 1.40A 2j0hC-3nfvA:
0.0		 2j0hC-3nfvA:
19.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2J0H_E_ACHE1289_0
(FICOLIN-2)		 3nfv ALGINATE LYASE
(Bacteroides
ovatus) 		4 / 4 ARG A  53
ASP A  54
THR A  50
LYS A  57
 None
 1.40A 2j0hE-3nfvA:
0.0		 2j0hE-3nfvA:
19.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2J0H_F_ACHF1289_0
(FICOLIN-2)		 3nfv ALGINATE LYASE
(Bacteroides
ovatus) 		4 / 4 ARG A  53
ASP A  54
THR A  50
LYS A  57
 None
 1.40A 2j0hF-3nfvA:
0.0		 2j0hF-3nfvA:
19.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2J2P_B_SC2B1289_1
(FICOLIN-2)		 3nfv ALGINATE LYASE
(Bacteroides
ovatus) 		4 / 4 ARG A  53
ASP A  54
THR A  50
LYS A  57
 None
 1.23A 2j2pB-3nfvA:
0.0		 2j2pB-3nfvA:
19.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2J2P_C_SC2C1290_1
(FICOLIN-2)		 3nfv ALGINATE LYASE
(Bacteroides
ovatus) 		4 / 4 ARG A  53
ASP A  54
THR A  50
LYS A  57
 None
 1.33A 2j2pC-3nfvA:
0.0		 2j2pC-3nfvA:
19.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2J2P_F_SC2F1290_1
(FICOLIN-2)		 3nfv ALGINATE LYASE
(Bacteroides
ovatus) 		4 / 4 ARG A  53
ASP A  54
THR A  50
LYS A  57
 None
 1.33A 2j2pF-3nfvA:
0.0		 2j2pF-3nfvA:
19.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A35_A_RBFA191_1
(LUMAZINE PROTEIN)		 3nfv ALGINATE LYASE
(Bacteroides
ovatus) 		5 / 12 ASP A 259
GLN A 258
ALA A 261
THR A 249
ILE A 309
 None
 1.13A 3a35A-3nfvA:
undetectable		 3a35A-3nfvA:
16.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CCF_B_BEZB261_0
(CYCLOPROPANE-FATTY-A
CYL-PHOSPHOLIPID
SYNTHASE)		 3nfv ALGINATE LYASE
(Bacteroides
ovatus) 		4 / 8 HIS A 240
ASN A 239
TYR A 295
ARG A 289
 None
None
EDO  A 407 (-4.1A)
EDO  A 406 (-3.3A)
 1.25A 3ccfB-3nfvA:
undetectable		 3ccfB-3nfvA:
21.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NS1_L_PM6L1_1
(XANTHINE
DEHYDROGENASE/OXIDAS
E)		 3nfv ALGINATE LYASE
(Bacteroides
ovatus) 		4 / 8 THR A 321
LEU A 273
ALA A 331
ALA A 330
 EDO  A 415 (-4.9A)
None
None
EDO  A 405 ( 3.7A)
 0.86A 3ns1L-3nfvA:
undetectable		 3ns1L-3nfvA:
19.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ZQ8_D_DVAD8_0
(VAL-GRAMICIDIN A)		 3nfv ALGINATE LYASE
(Bacteroides
ovatus) 		3 / 3 TRP A 216
VAL A 151
TRP A 152
 None
 1.21A 3zq8C-3nfvA:
undetectable
3zq8D-3nfvA:
undetectable		 3zq8C-3nfvA:
3.06
3zq8D-3nfvA:
3.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4J7X_B_SASB804_1
(SEPIAPTERIN
REDUCTASE)		 3nfv ALGINATE LYASE
(Bacteroides
ovatus) 		5 / 12 LEU A 293
GLN A 283
ALA A 331
GLY A 301
LEU A 300
 None
None
None
EDO  A 412 (-3.5A)
None
 1.26A 4j7xB-3nfvA:
undetectable		 4j7xB-3nfvA:
19.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M11_A_MXMA606_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 3nfv ALGINATE LYASE
(Bacteroides
ovatus) 		5 / 12 MET A 303
LEU A 300
ILE A 277
LEU A 273
LEU A 332
 None
 1.33A 4m11A-3nfvA:
undetectable		 4m11A-3nfvA:
21.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OKN_B_KANB403_1
(L-LACTATE
DEHYDROGENASE A
CHAIN)		 3nfv ALGINATE LYASE
(Bacteroides
ovatus) 		5 / 9 VAL A 246
ALA A 310
ILE A 265
PHE A 268
ILE A 317
 None
None
None
None
EDO  A 410 (-4.7A)
 1.49A 4oknB-3nfvA:
undetectable		 4oknB-3nfvA:
23.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4P65_I_IPHI101_0
(INSULIN)		 3nfv ALGINATE LYASE
(Bacteroides
ovatus) 		5 / 12 LEU A 304
ILE A 297
LEU A 332
LEU A 365
ALA A 368
 None
 1.01A 4p65B-3nfvA:
undetectable
4p65D-3nfvA:
undetectable
4p65I-3nfvA:
undetectable
4p65J-3nfvA:
undetectable		 4p65B-3nfvA:
9.38
4p65D-3nfvA:
9.38
4p65I-3nfvA:
4.03
4p65J-3nfvA:
9.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4P65_K_IPHK101_0
(INSULIN)		 3nfv ALGINATE LYASE
(Bacteroides
ovatus) 		5 / 12 LEU A 304
ILE A 297
LEU A 332
LEU A 365
ALA A 368
 None
 1.00A 4p65F-3nfvA:
undetectable
4p65H-3nfvA:
undetectable
4p65K-3nfvA:
undetectable
4p65L-3nfvA:
undetectable		 4p65F-3nfvA:
9.38
4p65H-3nfvA:
9.38
4p65K-3nfvA:
4.03
4p65L-3nfvA:
9.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V32_C_EF2C151_1
(CEREBLON ISOFORM 4)		 3nfv ALGINATE LYASE
(Bacteroides
ovatus) 		4 / 7 ASN A 161
TRP A 216
TRP A 152
PHE A 189
 None
 1.30A 4v32C-3nfvA:
undetectable		 4v32C-3nfvA:
15.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KMD_C_6UBC1304_1
(ION TRANSPORT
PROTEIN)		 3nfv ALGINATE LYASE
(Bacteroides
ovatus) 		4 / 5 TYR A 187
ILE A 184
LEU A 300
GLY A 301
 None
None
None
EDO  A 412 (-3.5A)
 0.91A 5kmdC-3nfvA:
undetectable
5kmdD-3nfvA:
undetectable		 5kmdC-3nfvA:
20.05
5kmdD-3nfvA:
20.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LJB_A_RTLA201_0
(RETINOL-BINDING
PROTEIN 1)		 3nfv ALGINATE LYASE
(Bacteroides
ovatus) 		5 / 12 ALA A 145
SER A 202
PHE A 205
TYR A 134
LEU A  52
 None
 1.36A 5ljbA-3nfvA:
undetectable		 5ljbA-3nfvA:
17.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MZR_E_PFLE409_1
(PROTON-GATED ION
CHANNEL)		 3nfv ALGINATE LYASE
(Bacteroides
ovatus) 		4 / 8 TYR A 187
ILE A 309
THR A 190
ILE A 193
 None
 0.93A 5mzrE-3nfvA:
undetectable		 5mzrE-3nfvA:
9.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5YJS_A_SALA603_0
(VICILIN-LIKE
ANTIMICROBIAL
PEPTIDES 2-2)		 3nfv ALGINATE LYASE
(Bacteroides
ovatus) 		5 / 11 GLY A 182
ASN A 174
ARG A 179
VAL A 229
GLY A 180
 None
EDO  A 409 (-3.2A)
EDO  A 406 ( 2.9A)
None
None
 1.48A 5yjsA-3nfvA:
undetectable		 5yjsA-3nfvA:
10.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DH0_A_017A101_2
(PROTEASE)		 3nfv ALGINATE LYASE
(Bacteroides
ovatus) 		3 / 3 LEU A 304
ASP A 245
ILE A 265
 None
 0.55A 6dh0B-3nfvA:
undetectable		 6dh0B-3nfvA:
11.29