SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3nfw'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1LQT_A_ACTA1871_0 (FPRA)	3nfw	FLAVIN REDUCTASE-LIKE, FMN-BINDING PROTEIN (Mycolicibacteriu m thermoresistibil e)	4 / 7	PRO A 33 ALA A 96 PHE A 95 TRP A 100	None	1.18A	1lqtA-3nfwA: undetectable	1lqtA-3nfwA: 20.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1LQU_A_ACTA1428_0 (FPRA)	3nfw	FLAVIN REDUCTASE-LIKE, FMN-BINDING PROTEIN (Mycolicibacteriu m thermoresistibil e)	4 / 7	PRO A 33 ALA A 96 PHE A 95 TRP A 100	None	1.18A	1lquA-3nfwA: undetectable	1lquA-3nfwA: 20.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2QD5_A_CHDA701_0 (FERROCHELATASE)	3nfw	FLAVIN REDUCTASE-LIKE, FMN-BINDING PROTEIN (Mycolicibacteriu m thermoresistibil e)	4 / 8	LEU A 105 PRO A 49 VAL A 51 GLY A 135	None	1.11A	2qd5A-3nfwA: undetectable	2qd5A-3nfwA: 18.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4WOZ_B_MN9B401_0 (N-ACETYLNEURAMINATE LYASE)	3nfw	FLAVIN REDUCTASE-LIKE, FMN-BINDING PROTEIN (Mycolicibacteriu m thermoresistibil e)	4 / 6	SER A 45 LEU A 46 ASP A 47 LEU A 179	None	0.96A	4wozA-3nfwA: undetectable 4wozB-3nfwA: undetectable	4wozA-3nfwA: 18.21 4wozB-3nfwA: 18.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6FGD_A_ACTA826_0 (GEPHYRIN)	3nfw	FLAVIN REDUCTASE-LIKE, FMN-BINDING PROTEIN (Mycolicibacteriu m thermoresistibil e)	3 / 3	HIS A 116 ARG A 101 ILE A 109	None	0.55A	6fgdA-3nfwA: undetectable	6fgdA-3nfwA: 18.91

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["1LQT_A_ACTA1871_0","FPRA","3nfw","FLAVIN REDUCTASE-LIKE, FMN-BINDING PROTEIN","Mycolicibacterium thermoresistibile",4,"PRO A  33;ALA A  96;PHE A  95;TRP A 100","None","1.18A","1lqtA-3nfwA:undetectable","1lqtA-3nfwA:20.43"],["1LQU_A_ACTA1428_0","FPRA","3nfw","FLAVIN REDUCTASE-LIKE, FMN-BINDING PROTEIN","Mycolicibacterium thermoresistibile",4,"PRO A  33;ALA A  96;PHE A  95;TRP A 100","None","1.18A","1lquA-3nfwA:undetectable","1lquA-3nfwA:20.43"],["2QD5_A_CHDA701_0","FERROCHELATASE","3nfw","FLAVIN REDUCTASE-LIKE, FMN-BINDING PROTEIN","Mycolicibacterium thermoresistibile",4,"LEU A 105;PRO A  49;VAL A  51;GLY A 135","None","1.11A","2qd5A-3nfwA:undetectable","2qd5A-3nfwA:18.21"],["4WOZ_B_MN9B401_0","N-ACETYLNEURAMINATE LYASE","3nfw","FLAVIN REDUCTASE-LIKE, FMN-BINDING PROTEIN","Mycolicibacterium thermoresistibile",4,"SER A  45;LEU A  46;ASP A  47;LEU A 179","None","0.96A","4wozA-3nfwA:undetectable;4wozB-3nfwA:undetectable","4wozA-3nfwA:18.21;4wozB-3nfwA:18.21"],["6FGD_A_ACTA826_0","GEPHYRIN","3nfw","FLAVIN REDUCTASE-LIKE, FMN-BINDING PROTEIN","Mycolicibacterium thermoresistibile",3,"HIS A 116;ARG A 101;ILE A 109","None","0.55A","6fgdA-3nfwA:undetectable","6fgdA-3nfwA:18.91"]]