SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3nfz'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BNN_A_FCNA1199_1
(EPOXIDASE)		 3nfz ASPARTOACYLASE-2
(Mus
musculus) 		5 / 9 TYR A 287
ASN A  70
HIS A  21
GLU A  24
HIS A 116
 3NF  A 322 (-4.4A)
3NF  A 322 (-3.9A)
ZN  A 319 ( 3.4A)
ZN  A 319 ( 2.1A)
ZN  A 319 (-3.4A)
 1.41A 2bnnA-3nfzA:
undetectable
2bnnB-3nfzA:
0.0		 2bnnA-3nfzA:
23.31
2bnnB-3nfzA:
23.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HLW_B_CE3B302_2
(CTX-M-9
EXTENDED-SPECTRUM
BETA-LACTAMASE)		 3nfz ASPARTOACYLASE-2
(Mus
musculus) 		3 / 3 CYH A  26
PRO A 182
ASP A 189
 None
 0.86A 3hlwB-3nfzA:
undetectable		 3hlwB-3nfzA:
23.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PM5_A_CE3A301_2
(BETA-LACTAMASE
CTX-M-14)		 3nfz ASPARTOACYLASE-2
(Mus
musculus) 		3 / 3 CYH A  26
PRO A 182
ASP A 189
 None
 0.87A 4pm5A-3nfzA:
undetectable		 4pm5A-3nfzA:
23.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YO9_B_ACTB401_0
(3C-LIKE PROTEINASE)		 3nfz ASPARTOACYLASE-2
(Mus
musculus) 		3 / 3 ARG A 232
ASP A 229
TYR A 288
 None
 0.89A 4yo9B-3nfzA:
undetectable		 4yo9B-3nfzA:
22.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DV4_A_NMYA601_1
(CCR4-NOT
TRANSCRIPTION
COMPLEX SUBUNIT
6-LIKE)		 3nfz ASPARTOACYLASE-2
(Mus
musculus) 		5 / 12 LEU A 100
HIS A 116
LEU A 138
PHE A 111
ILE A 174
 None
ZN  A 319 (-3.4A)
None
None
None
 1.11A 5dv4A-3nfzA:
undetectable		 5dv4A-3nfzA:
20.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HBS_A_RTLA201_1
(RETINOL-BINDING
PROTEIN 1)		 3nfz ASPARTOACYLASE-2
(Mus
musculus) 		4 / 8 LEU A 115
LEU A  52
TYR A  33
GLN A  42
 None
 1.19A 5hbsA-3nfzA:
undetectable		 5hbsA-3nfzA:
16.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IEP_A_VDYA201_1
(CDL2.3B)		 3nfz ASPARTOACYLASE-2
(Mus
musculus) 		5 / 12 PHE A 134
LEU A 142
LEU A 126
PHE A 111
LEU A 115
 None
 1.21A 5iepA-3nfzA:
undetectable		 5iepA-3nfzA:
16.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X23_A_LSNA504_1
(CYTOCHROME P450 2C9)		 3nfz ASPARTOACYLASE-2
(Mus
musculus) 		4 / 8 ILE A 127
PHE A 281
PRO A 150
PHE A 251
 3NF  A 322 (-4.0A)
None
None
None
 1.01A 5x23A-3nfzA:
undetectable		 5x23A-3nfzA:
21.49