SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3ng3'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JIP_A_KTNA801_1
(CYTOCHROME P450
107A1)		 3ng3 DEOXYRIBOSE-PHOSPHAT
E ALDOLASE
(Mycobacterium
avium) 		5 / 12 ALA A 207
LEU A 200
ALA A 197
THR A 159
LEU A 210
 None
None
CL  A 224 ( 3.8A)
None
None
 1.35A 1jipA-3ng3A:
undetectable		 1jipA-3ng3A:
23.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NBH_A_SAMA293_0
(GLYCINE
N-METHYLTRANSFERASE)		 3ng3 DEOXYRIBOSE-PHOSPHAT
E ALDOLASE
(Mycobacterium
avium) 		5 / 12 ILE A  95
VAL A 126
ALA A 207
MET A 177
SER A 190
 None
None
None
None
UNL  A 301 ( 3.6A)
 1.40A 1nbhA-3ng3A:
2.5		 1nbhA-3ng3A:
22.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NBH_D_SAMD3293_0
(GLYCINE
N-METHYLTRANSFERASE)		 3ng3 DEOXYRIBOSE-PHOSPHAT
E ALDOLASE
(Mycobacterium
avium) 		5 / 12 ILE A  95
VAL A 126
ALA A 207
MET A 177
SER A 190
 None
None
None
None
UNL  A 301 ( 3.6A)
 1.39A 1nbhD-3ng3A:
undetectable		 1nbhD-3ng3A:
22.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Q23_E_FUAE706_2
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 3ng3 DEOXYRIBOSE-PHOSPHAT
E ALDOLASE
(Mycobacterium
avium) 		4 / 4 ALA A  80
VAL A 115
ALA A  77
HIS A  78
 None
 1.24A 1q23F-3ng3A:
undetectable		 1q23F-3ng3A:
19.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A1M_A_CAMA1422_0
(CYTOCHROME P450-CAM)		 3ng3 DEOXYRIBOSE-PHOSPHAT
E ALDOLASE
(Mycobacterium
avium) 		4 / 7 PHE A  66
THR A  15
GLY A 191
THR A 159
 None
UNL  A 301 ( 3.3A)
UNL  A 301 ( 4.2A)
None
 0.94A 2a1mA-3ng3A:
undetectable		 2a1mA-3ng3A:
20.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2GEH_A_NHYA300_1
(CARBONIC ANHYDRASE 2)		 3ng3 DEOXYRIBOSE-PHOSPHAT
E ALDOLASE
(Mycobacterium
avium) 		4 / 8 HIS A  14
VAL A  12
VAL A  38
LEU A 219
 None
 0.85A 2gehA-3ng3A:
undetectable		 2gehA-3ng3A:
20.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HUO_B_PNNB301_0
(CTX-M-9
EXTENDED-SPECTRUM
BETA-LACTAMASE)		 3ng3 DEOXYRIBOSE-PHOSPHAT
E ALDOLASE
(Mycobacterium
avium) 		5 / 12 GLY A 162
GLY A 191
SER A 190
GLY A 211
ASP A  13
 UNL  A 301 ( 4.0A)
UNL  A 301 ( 4.2A)
UNL  A 301 ( 3.6A)
UNL  A 301 ( 4.6A)
None
 1.02A 3huoB-3ng3A:
undetectable		 3huoB-3ng3A:
22.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RFQ_A_SAMA401_1
(HISTIDINE PROTEIN
METHYLTRANSFERASE 1
HOMOLOG)		 3ng3 DEOXYRIBOSE-PHOSPHAT
E ALDOLASE
(Mycobacterium
avium) 		4 / 4 THR A 159
GLY A 192
ASP A 198
SER A 160
 None
None
CL  A 224 ( 4.7A)
None
 1.24A 4rfqA-3ng3A:
undetectable		 4rfqA-3ng3A:
22.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4TWD_A_377A402_1
(CYS-LOOP
LIGAND-GATED ION
CHANNEL)		 3ng3 DEOXYRIBOSE-PHOSPHAT
E ALDOLASE
(Mycobacterium
avium) 		5 / 9 ALA A 169
SER A 160
ALA A 173
SER A 130
ALA A 189
 None
 1.32A 4twdA-3ng3A:
undetectable
4twdB-3ng3A:
undetectable
4twdC-3ng3A:
undetectable
4twdD-3ng3A:
undetectable
4twdE-3ng3A:
undetectable		 4twdA-3ng3A:
20.38
4twdB-3ng3A:
20.38
4twdC-3ng3A:
20.38
4twdD-3ng3A:
20.38
4twdE-3ng3A:
20.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4TWD_A_377A402_1
(CYS-LOOP
LIGAND-GATED ION
CHANNEL)		 3ng3 DEOXYRIBOSE-PHOSPHAT
E ALDOLASE
(Mycobacterium
avium) 		5 / 9 ALA A 207
ALA A 189
ALA A 169
SER A 130
ALA A 205
 None
 1.27A 4twdA-3ng3A:
undetectable
4twdB-3ng3A:
undetectable
4twdC-3ng3A:
undetectable
4twdD-3ng3A:
undetectable
4twdE-3ng3A:
undetectable		 4twdA-3ng3A:
20.38
4twdB-3ng3A:
20.38
4twdC-3ng3A:
20.38
4twdD-3ng3A:
20.38
4twdE-3ng3A:
20.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JNC_D_ACTD305_0
(CARBONIC ANHYDRASE 4)		 3ng3 DEOXYRIBOSE-PHOSPHAT
E ALDOLASE
(Mycobacterium
avium) 		4 / 5 ALA A  64
ALA A  80
ILE A  91
LEU A 124
 None
 0.72A 5jncD-3ng3A:
undetectable		 5jncD-3ng3A:
20.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BXN_A_SAMA901_0
(DIPHTHAMIDE
BIOSYNTHESIS ENZYME
DPH2)		 3ng3 DEOXYRIBOSE-PHOSPHAT
E ALDOLASE
(Mycobacterium
avium) 		5 / 12 LEU A 136
VAL A 126
ILE A  95
ASP A  96
ASP A 111
 None
 1.43A 6bxnA-3ng3A:
undetectable		 6bxnA-3ng3A:
19.82